Aberrant phase separation and nucleolar dysfunction in rare genetic diseases.
Nature
Mensah, Martin A MA; Niskanen, Henri H; Magalhaes, Alexandre P AP; Basu, Shaon S; Kircher, Martin M; Sczakiel, Henrike L HL; Reiter, Alisa M V AMV; Elsner, Jonas J; Meinecke, Peter P; Biskup, Saskia S; Chung, Brian H Y BHY; Dombrowsky, Gregor G; Eckmann-Scholz, Christel C; Hitz, Marc Phillip MP; Hoischen, Alexander A; Holterhus, Paul-Martin PM; Hülsemann, Wiebke W; Kahrizi, Kimia K; Kalscheuer, Vera M VM; Kan, Anita A; Krumbiegel, Mandy M; Kurth, Ingo I; Leubner, Jonas J; Longardt, Ann Carolin AC; Moritz, Jörg D JD; Najmabadi, Hossein H; Skipalova, Karolina K; Snijders Blok, Lot L; Tzschach, Andreas A; Wiedersberg, Eberhard E; Zenker, Martin M; Garcia-Cabau, Carla C; Buschow, René R; Salvatella, Xavier X; Kraushar, Matthew L ML; Mundlos, Stefan S; Caliebe, Almuth A; Spielmann, Malte M; Horn, Denise D; Hnisz, Denes D
Publication Date: 2023-02-08
Variant appearance in text: TP53: 1115A>G; Lys372Arg
Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.
Exosome-dependent immune surveillance at the metastatic niche requires BAG6 and CBP/p300-dependent acetylation of p53.
Theranostics
Schuldner, Maximiliane M; Dörsam, Bastian B; Shatnyeva, Olga O; Reiners, Katrin S KS; Kubarenko, Andriy A; Hansen, Hinrich P HP; Finkernagel, Florian F; Roth, Katrin K; Theurich, Sebastian S; Nist, Andrea A; Stiewe, Thorsten T; Paschen, Annette A; Knittel, Gero G; Reinhardt, Hans C HC; Müller, Rolf R; Hallek, Michael M; von Strandmann, Elke Pogge EP
From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.
Cold Spring Harbor Molecular Case Studies
Quinn, Emily A EA; Maciaszek, Jamie L JL; Pinto, Emilia M EM; Phillips, Aaron H AH; Berdy, David D; Khandwala, Mohammad M; Upadhyaya, Santhosh A SA; Zambetti, Gerard P GP; Kriwacki, Richard W RW; Ellison, David W DW; Nichols, Kim E KE; Kesserwan, Chimene C
Publication Date: 2019-08
Variant appearance in text: TP53: 1115A>G; Lys372Arg
appreci8: a pipeline for precise variant calling integrating 8 tools.
Bioinformatics (Oxford, England)
Sandmann, Sarah S; Karimi, Mohsen M; de Graaf, Aniek O AO; Rohde, Christian C; Göllner, Stefanie S; Varghese, Julian J; Ernsting, Jan J; Walldin, Gunilla G; van der Reijden, Bert A BA; Müller-Tidow, Carsten C; Malcovati, Luca L; Hellström-Lindberg, Eva E; Jansen, Joop H JH; Dugas, Martin M
Publication Date: 2018-12-15
Variant appearance in text: TP53: 1115A>G; Lys372Arg
USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells.
Nature Communications
Padmanabhan, Achuth A; Candelaria, Nicholes N; Wong, Kwong-Kwok KK; Nikolai, Bryan C BC; Lonard, David M DM; O'Malley, Bert W BW; Richards, JoAnne S JS
Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer.
Oncotarget
Alzoubi, Samer S; Brody, Leigh L; Rahman, Sunniyat S; Mahul-Mellier, Anne-Laure AL; Mercado, Nicolas N; Ito, Kazuhiro K; El-Bahrawy, Mona M; Silver, Andrew A; Boobis, Alan A; Bell, Jimmy D JD; Hajji, Nabil N
Adenovirus E1B 55-kilodalton protein is a p53-SUMO1 E3 ligase that represses p53 and stimulates its nuclear export through interactions with promyelocytic leukemia nuclear bodies.
Journal Of Virology
Pennella, Mario A MA; Liu, Yue Y; Woo, Jennifer L JL; Kim, Chongwoo A CA; Berk, Arnold J AJ
Methylation-acetylation interplay activates p53 in response to DNA damage.
Molecular And Cellular Biology
Ivanov, Gleb S GS; Ivanova, Tatyana T; Kurash, Julia J; Ivanov, Alexey A; Chuikov, Sergey S; Gizatullin, Farid F; Herrera-Medina, Enrique M EM; Rauscher, Frank F; Reinberg, Danny D; Barlev, Nickolai A NA