Publications:

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Genetic mutations in HER2-positive breast cancer: possible association with response to trastuzumab therapy.

Human Genomics

Zakaria, Nermine H NH; Hashad, Doaa D; Saied, Marwa H MH; Hegazy, Neamat N; Elkayal, Alyaa A; Tayae, Eman E

Publication Date: 2023-05-18

Variant appearance in text: TP53: Ser366Ala; rs17881470

PubMed Link: 37202799

Variant Present in the following documents:

• Main text
• 40246_2023_Article_493.pdf

View BVdb publication page

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Evaluation of AlphaFold structure-based protein stability prediction on missense variations in cancer.

Frontiers In Genetics

Keskin Karakoyun, Hilal H; Yüksel, Şirin K ŞK; Amanoglu, Ilayda I; Naserikhojasteh, Lara L; Yeşilyurt, Ahmet A; Yakıcıer, Cengiz C; Timuçin, Emel E; Akyerli, Cemaliye B CB

Publication Date: 2023

Variant appearance in text: TP53: S366A

PubMed Link: 36896237

Variant Present in the following documents:

• Table1.xlsx, sheet 1

View BVdb publication page

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Aberrant phase separation and nucleolar dysfunction in rare genetic diseases.

Nature

Mensah, Martin A MA; Niskanen, Henri H; Magalhaes, Alexandre P AP; Basu, Shaon S; Kircher, Martin M; Sczakiel, Henrike L HL; Reiter, Alisa M V AMV; Elsner, Jonas J; Meinecke, Peter P; Biskup, Saskia S; Chung, Brian H Y BHY; Dombrowsky, Gregor G; Eckmann-Scholz, Christel C; Hitz, Marc Phillip MP; Hoischen, Alexander A; Holterhus, Paul-Martin PM; Hülsemann, Wiebke W; Kahrizi, Kimia K; Kalscheuer, Vera M VM; Kan, Anita A; Krumbiegel, Mandy M; Kurth, Ingo I; Leubner, Jonas J; Longardt, Ann Carolin AC; Moritz, Jörg D JD; Najmabadi, Hossein H; Skipalova, Karolina K; Snijders Blok, Lot L; Tzschach, Andreas A; Wiedersberg, Eberhard E; Zenker, Martin M; Garcia-Cabau, Carla C; Buschow, René R; Salvatella, Xavier X; Kraushar, Matthew L ML; Mundlos, Stefan S; Caliebe, Almuth A; Spielmann, Malte M; Horn, Denise D; Hnisz, Denes D

Publication Date: 2023-02-08

Variant appearance in text: N/A

PubMed Link: 36755093

Variant Present in the following documents:

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: TP53: S366A

PubMed Link: 36561320

Variant Present in the following documents:

• Table3.xlsx, sheet 1
• Table2.xlsx, sheet 7

View BVdb publication page

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: p53: 1096T>G

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: TP53: S366A

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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TP53_PROF: a machine learning model to predict impact of missense mutations in TP53.

Briefings In Bioinformatics

Ben-Cohen, Gil G; Doffe, Flora F; Devir, Michal M; Leroy, Bernard B; Soussi, Thierry T; Rosenberg, Shai S

Publication Date: 2022-03-10

Variant appearance in text: TP53: 1096T>G; S366A; rs17881470

PubMed Link: 35043155

Variant Present in the following documents:

• Main text
• bbab524.pdf
• supplementary_table_s7_bbab524.xlsx, sheet 2
• supplementary_figure_s4a_and_b_bbab524.pdf

View BVdb publication page

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Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition.

Molecular & Cellular Proteomics : Mcp

Schmitt, Marisa M; Sinnberg, Tobias T; Bratl, Katrin K; Zittlau, Katharina K; Garbe, Claus C; Macek, Boris B; Nalpas, Nicolas C NC

Publication Date: 2021-10-19

Variant appearance in text: p53: S366A

PubMed Link: 34673281

Variant Present in the following documents:

• mmc2.xlsx, sheet 6

View BVdb publication page

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Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition.

Molecular & Cellular Proteomics : Mcp

Schmitt, Marisa M; Sinnberg, Tobias T; Bratl, Katrin K; Zittlau, Katharina K; Garbe, Claus C; Macek, Boris B; Nalpas, Nicolas C NC

Publication Date: 2021

Variant appearance in text: p53: S366A

PubMed Link: 34673281

Variant Present in the following documents:

• mmc2.xlsx, sheet 6

View BVdb publication page

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A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports

Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM

Publication Date: 2021-07-12

Variant appearance in text: TP53: 1096T>G; Ser366Ala; rs17881470

PubMed Link: 34253785

Variant Present in the following documents:

• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 4
• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 8
• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 6

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: TP53: 1096T>G; S366A

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Specifications of the ACMG/AMP variant interpretation guidelines for germline TP53 variants.

Human Mutation

Fortuno, Cristina C; Lee, Kristy K; Olivier, Magali M; Pesaran, Tina T; Mai, Phuong L PL; de Andrade, Kelvin C KC; Attardi, Laura D LD; Crowley, Stephanie S; Evans, D Gareth DG; Feng, Bing-Jian BJ; Foreman, Ann K M AKM; Frone, Megan N MN; Huether, Robert R; James, Paul A PA; McGoldrick, Kelly K; Mester, Jessica J; Seifert, Bryce A BA; Slavin, Thomas P TP; Witkowski, Leora L; Zhang, Liying L; Plon, Sharon E SE; Spurdle, Amanda B AB; Savage, Sharon A SA; ,

Publication Date: 2021-03

Variant appearance in text: TP53: 1096T>G

PubMed Link: 33300245

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.

Cell Death And Differentiation

Doffe, Flora F; Carbonnier, Vincent V; Tissier, Manon M; Leroy, Bernard B; Martins, Isabelle I; Mattsson, Johanna S M JSM; Micke, Patrick P; Pavlova, Sarka S; Pospisilova, Sarka S; Smardova, Jana J; Joerger, Andreas C AC; Wiman, Klas G KG; Kroemer, Guido G; Soussi, Thierry T

Publication Date: 2021-05

Variant appearance in text: p53: S366A

PubMed Link: 33257846

Variant Present in the following documents:

• Main text
• 41418_2020_Article_672.pdf
• 41418_2020_672_MOESM3_ESM.xlsx, sheet 4

View BVdb publication page

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Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.

Cell Death And Differentiation

Doffe, Flora F; Carbonnier, Vincent V; Tissier, Manon M; Leroy, Bernard B; Martins, Isabelle I; Mattsson, Johanna S M JSM; Micke, Patrick P; Pavlova, Sarka S; Pospisilova, Sarka S; Smardova, Jana J; Joerger, Andreas C AC; Wiman, Klas G KG; Kroemer, Guido G; Soussi, Thierry T

Publication Date: 2021-05

Variant appearance in text: p53: S366A

PubMed Link: 33257846

Variant Present in the following documents:

• Main text
• 41418_2020_Article_672.pdf
• 41418_2020_672_MOESM3_ESM.xlsx, sheet 4

View BVdb publication page

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Validation and clinical application of a targeted next-generation sequencing gene panel for solid and hematologic malignancies.

Peerj

Prieto-Potin, Iván I; Carvajal, Nerea N; Plaza-Sánchez, Jenifer J; Manso, Rebeca R; Aúz-Alexandre, Carmen Laura CL; Chamizo, Cristina C; Zazo, Sandra S; López-Sánchez, Almudena A; Rodríguez-Pinilla, Socorro María SM; Camacho, Laura L; Longarón, Raquel R; Bellosillo, Beatriz B; Somoza, Rosa R; Hernández-Losa, Javier J; Fernández-Soria, Víctor Manuel VM; Ramos-Ruiz, Ricardo R; Cristóbal, Ion I; García-Foncillas, Jesús J; Rojo, Federico F

Publication Date: 2020

Variant appearance in text: TP53: 1096T>G; Ser366Ala; rs17881470

PubMed Link: 33083132

Variant Present in the following documents:

• peerj-08-10069-s013.xlsx, sheet 1
• peerj-08-10069-s012.xlsx, sheet 1
• peerj-08-10069-s009.xlsx, sheet 1
• peerj-08-10069-s010.xlsx, sheet 1

View BVdb publication page

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Gene panel screening for insight towards breast cancer susceptibility in different ethnicities.

Plos One

Bishop, Madison R MR; Omeler-Fenaud, Sophonie M SM; Huskey, Anna L W ALW; Merner, Nancy D ND

Publication Date: 2020

Variant appearance in text: TP53: S366A

PubMed Link: 32866190

Variant Present in the following documents:

• pone.0238295.s002.xlsx, sheet 1

View BVdb publication page

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Monitoring of clonal evolution of acute myeloid leukemia identifies the leukemia subtype, clinical outcome and potential new drug targets for post-remission strategies or relapse.

Haematologica

Onecha, Esther E; Rapado, Inmaculada I; Luz Morales, María M; Carreño-Tarragona, Gonzalo G; Martinez-Sanchez, Pilar P; Gutierrez, Xabier X; Sáchez Pina, José María JM; Linares, María M; Gallardo, Miguel M; Martinez-López, Joaquín J; Ayala, Rosa R

Publication Date: 2021-09-01

Variant appearance in text: TP53: 1096T>G; Ser366Ala

PubMed Link: 32732356

Variant Present in the following documents:

• 2020_254623_ONECHA_SUPPL.pdf

View BVdb publication page

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Defining relative mutational difficulty to understand cancer formation.

Cell Discovery

Shan, Lin L; Yu, Jiao J; He, Zhengjin Z; Chen, Shishuang S; Liu, Mingxian M; Ding, Hongyu H; Xu, Liang L; Zhao, Jie J; Yang, Ailing A; Jiang, Hai H

Publication Date: 2020

Variant appearance in text: p53: S366A

PubMed Link: 32704382

Variant Present in the following documents:

• 41421_2020_177_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Role of the RNA-binding protein La in cancer pathobiology.

Rna Biology

Sommer, Gunhild G; Heise, Tilman T

Publication Date: 2021-02

Variant appearance in text: p53: S366A

PubMed Link: 32687431

Variant Present in the following documents:

• Main text

View BVdb publication page

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A step towards personalizing next line therapy for resected pancreatic and related cancer patients: A single institution's experience.

Surgical Oncology

Lowder, Cinthya Y CY; Dhir, Teena T; Goetz, Austin B AB; Thomsett, Henry L HL; Bender, Joseph J; Tatarian, Talar T; Madhavan, Subha S; Petricoin, Emanuel F EF; Blais, Edik E; Lavu, Harish H; Winter, Jordan M JM; Posey, James J; Brody, Jonathan R JR; Pishvaian, Michael J MJ; Yeo, Charles J CJ

Publication Date: 2020-06

Variant appearance in text: p53: S366A

PubMed Link: 32561076

Variant Present in the following documents:

• Main text
• nihms-1621334.pdf

View BVdb publication page

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Targeted next-generation sequencing of 565 neuro-oncology patients at UCLA: A single-institution experience.

Neuro-Oncology Advances

Ji, Matthew S MS; Eldred, Blaine S C BSC; Liu, Regina R; Pianka, Sean T ST; Molaie, Donna D; Kevan, Bryan B; Pan, Stephanie S; Lai, Thomas J TJ; Nguyen, Nhung T NT; Chow, Frances E FE; Yong, William H WH; Cox, Christopher D CD; Reeh, Devin N DN; Li, Tie T; Liau, Linda M LM; Nghiemphu, Phioanh L PL; Cloughesy, Timothy F TF; Li, Gang G; Lai, Albert A

Publication Date: 2020

Variant appearance in text: TP53: S366A

PubMed Link: 32118206

Variant Present in the following documents:

• Main text

View BVdb publication page

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A research-based gene panel to investigate breast, ovarian and prostate cancer genetic risk.

Plos One

Bishop, Madison R MR; Huskey, Anna L W ALW; Hetzel, John J; Merner, Nancy D ND

Publication Date: 2019

Variant appearance in text: TP53: 1096T>G; S366A

PubMed Link: 31415627

Variant Present in the following documents:

• Main text

View BVdb publication page

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Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint.

Elife

Bigot, Nicolas N; Day, Matthew M; Baldock, Robert A RA; Watts, Felicity Z FZ; Oliver, Antony W AW; Pearl, Laurence H LH

Publication Date: 2019-05-28

Variant appearance in text: TP53: S366A

PubMed Link: 31135337

Variant Present in the following documents:

• elife-44353.pdf

View BVdb publication page

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: TP53: S366A

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

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From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.

Cold Spring Harbor Molecular Case Studies

Quinn, Emily A EA; Maciaszek, Jamie L JL; Pinto, Emilia M EM; Phillips, Aaron H AH; Berdy, David D; Khandwala, Mohammad M; Upadhyaya, Santhosh A SA; Zambetti, Gerard P GP; Kriwacki, Richard W RW; Ellison, David W DW; Nichols, Kim E KE; Kesserwan, Chimene C

Publication Date: 2019-08

Variant appearance in text: TP53: 1096T>G; Ser366Ala

PubMed Link: 30886117

Variant Present in the following documents:

• supp_mcs.a003921_Supplemental_Table_2.xlsx, sheet 1
• supp_mcs.a003921_Supplemental_Table_1a.xlsx, sheet 1

View BVdb publication page

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Targeted mutation detection in breast cancer using MammaSeq™.

Breast Cancer Research : Bcr

Smith, Nicholas G NG; Gyanchandani, Rekha R; Shah, Osama S OS; Gurda, Grzegorz T GT; Lucas, Peter C PC; Hartmaier, Ryan J RJ; Brufsky, Adam M AM; Puhalla, Shannon S; Bahreini, Amir A; Kota, Karthik K; Wald, Abigail I AI; Nikiforov, Yuri E YE; Nikiforova, Marina N MN; Oesterreich, Steffi S; Lee, Adrian V AV

Publication Date: 2019-02-08

Variant appearance in text: TP53: S366A

PubMed Link: 30736836

Variant Present in the following documents:

• 13058_2019_1102_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Mechanism of IRSp53 inhibition by 14-3-3.

Nature Communications

Kast, David J DJ; Dominguez, Roberto R

Publication Date: 2019-01-29

Variant appearance in text: p53: S366A

PubMed Link: 30696821

Variant Present in the following documents:

• Main text
• 41467_2019_Article_8317.pdf

View BVdb publication page

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Variable population prevalence estimates of germline TP53 variants: A gnomAD-based analysis.

Human Mutation

de Andrade, Kelvin C KC; Frone, Megan N MN; Wegman-Ostrosky, Talia T; Khincha, Payal P PP; Kim, Jung J; Amadou, Amina A; Santiago, Karina M KM; Fortes, Fernanda P FP; Lemonnier, Nathanaël N; Mirabello, Lisa L; Stewart, Douglas R DR; Hainaut, Pierre P; Kowalski, Luiz P LP; Savage, Sharon A SA; Achatz, Maria I MI

Publication Date: 2019-01

Variant appearance in text: TP53: 1096T>G; S366A

PubMed Link: 30352134

Variant Present in the following documents:

• Main text

View BVdb publication page

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Combined assessment of the TNM stage and BRAF mutational status at diagnosis in sporadic colorectal cancer patients.

Oncotarget

Sayagués, José María JM; Del Carmen, Sofía S; Del Mar Abad, María M; Corchete, Luís Antonio LA; Bengoechea, Oscar O; Anduaga, María Fernanda MF; Baldeón, María Jesús MJ; Cruz, Juan Jesús JJ; Alcazar, Jose Antonio JA; Angoso, María M; González, Marcos M; García, Jacinto J; Muñoz-Bellvis, Luís L; Orfao, Alberto A; Sarasquete, María Eugenia ME

Publication Date: 2018-05-08

Variant appearance in text: TP53: S366A

PubMed Link: 29844874

Variant Present in the following documents:

• Main text
• oncotarget-09-24081.pdf

View BVdb publication page

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ERIC recommendations for TP53 mutation analysis in chronic lymphocytic leukemia-update on methodological approaches and results interpretation.

Leukemia

Malcikova, J J; Tausch, E E; Rossi, D D; Sutton, L A LA; Soussi, T T; Zenz, T T; Kater, A P AP; Niemann, C U CU; Gonzalez, D D; Davi, F F; Gonzalez Diaz, M M; Moreno, C C; Gaidano, G G; Stamatopoulos, K K; Rosenquist, R R; Stilgenbauer, S S; Ghia, P P; Pospisilova, S S; ,

Publication Date: 2018-05

Variant appearance in text: TP53: 1096T>G

PubMed Link: 29467486

Variant Present in the following documents:

• Main text
• 41375_2017_Article_7.pdf

View BVdb publication page

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Sources of discordance among germ-line variant classifications in ClinVar.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Yang, Shan S; Lincoln, Stephen E SE; Kobayashi, Yuya Y; Nykamp, Keith K; Nussbaum, Robert L RL; Topper, Scott S

Publication Date: 2017-10

Variant appearance in text: TP53: 1096T>G; Ser366Ala

PubMed Link: 28569743

Variant Present in the following documents:

• gim201760x7.xlsx, sheet 2

View BVdb publication page

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K63-polyubiquitinated HAUSP deubiquitinates HIF-1α and dictates H3K56 acetylation promoting hypoxia-induced tumour progression.

Nature Communications

Wu, Han-Tsang HT; Kuo, Yi-Chih YC; Hung, Jung-Jyh JJ; Huang, Chi-Hung CH; Chen, Wei-Yi WY; Chou, Teh-Ying TY; Chen, Yeh Y; Chen, Yi-Ju YJ; Chen, Yu-Ju YJ; Cheng, Wei-Chung WC; Teng, Shu-Chun SC; Wu, Kou-Juey KJ

Publication Date: 2016-12-09

Variant appearance in text: p53: S366A

PubMed Link: 27934968

Variant Present in the following documents:

• Main text
• ncomms13644.pdf

View BVdb publication page

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Proteome-wide Structural Analysis of PTM Hotspots Reveals Regulatory Elements Predicted to Impact Biological Function and Disease.

Molecular & Cellular Proteomics : Mcp

Torres, Matthew P MP; Dewhurst, Henry H; Sundararaman, Niveda N

Publication Date: 2016-11

Variant appearance in text: TP53: 1096T>G

PubMed Link: 27697855

Variant Present in the following documents:

• 10.1074_M116.062331_mcp.M116.062331-3.xlsx, sheet 5

View BVdb publication page

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Targeting survivin as a potential new treatment for chondrosarcoma of bone.

Oncogenesis

de Jong, Y Y; van Oosterwijk, J G JG; Kruisselbrink, A B AB; Briaire-de Bruijn, I H IH; Agrogiannis, G G; Baranski, Z Z; Cleven, A H G AH; Cleton-Jansen, A-M AM; van de Water, B B; Danen, E H J EH; Bovée, J V M G JV

Publication Date: 2016-05-09

Variant appearance in text: TP53: Ser366Ala

PubMed Link: 27159675

Variant Present in the following documents:

• oncsis201633x7.pdf

View BVdb publication page

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Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One

Holehouse, Alex S AS; Naegle, Kristen M KM

Publication Date: 2015

Variant appearance in text: rs17881470

PubMed Link: 26659599

Variant Present in the following documents:

• pone.0144692.s002.xlsx, sheet 1

View BVdb publication page

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: TP53: S366A

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 1

View BVdb publication page

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Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1/2-negative patients with early-onset breast cancer.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Maxwell, Kara N KN; Wubbenhorst, Bradley B; D'Andrea, Kurt K; Garman, Bradley B; Long, Jessica M JM; Powers, Jacquelyn J; Rathbun, Katherine K; Stopfer, Jill E JE; Zhu, Jiajun J; Bradbury, Angela R AR; Simon, Michael S MS; DeMichele, Angela A; Domchek, Susan M SM; Nathanson, Katherine L KL

Publication Date: 2015-08

Variant appearance in text: TP53: S366A; rs17881470

PubMed Link: 25503501

Variant Present in the following documents:

• NIHMS641969-supplement-Supplementary_Table_1.xls, sheet 1

View BVdb publication page

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: S366A

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Computational screening and molecular dynamic simulation of breast cancer associated deleterious non-synonymous single nucleotide polymorphisms in TP53 gene.

Plos One

Chitrala, Kumaraswamy Naidu KN; Yeguvapalli, Suneetha S

Publication Date: 2014

Variant appearance in text: TP53: S366A; rs17881470

PubMed Link: 25105660

Variant Present in the following documents:

• Main text
• pone.0104242.pdf

View BVdb publication page

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Germline variation in cancer-susceptibility genes in a healthy, ancestrally diverse cohort: implications for individual genome sequencing.

Plos One

Bodian, Dale L DL; McCutcheon, Justine N JN; Kothiyal, Prachi P; Huddleston, Kathi C KC; Iyer, Ramaswamy K RK; Vockley, Joseph G JG; Niederhuber, John E JE

Publication Date: 2014

Variant appearance in text: TP53: S366A; rs17881470

PubMed Link: 24728327

Variant Present in the following documents:

• pone.0094554.s002.xlsx, sheet 1

View BVdb publication page

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Identification of new p53 target microRNAs by bioinformatics and functional analysis.

Bmc Cancer

Bisio, Alessandra A; De Sanctis, Veronica V; Del Vescovo, Valerio V; Denti, Michela A MA; Jegga, Anil G AG; Inga, Alberto A; Ciribilli, Yari Y

Publication Date: 2013-11-21

Variant appearance in text: p53: S366A

PubMed Link: 24256616

Variant Present in the following documents:

• Main text

View BVdb publication page

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P53 and expression of immunological markers may identify early stage thyroid tumors.

Clinical & Developmental Immunology

Marcello, Marjory Alana MA; Morari, Elaine Cristina EC; Cunha, Lucas Leite LL; De Nadai Silva, Aline Carolina AC; Carraro, Dirce Maria DM; Carvalho, André Lopes AL; Soares, Fernando Augusto FA; Vassallo, José J; Ward, Laura Sterian LS

Publication Date: 2013

Variant appearance in text: TP53: S366A; rs17881470

PubMed Link: 24171036

Variant Present in the following documents:

• Main text
• CDI2013-846584.pdf

View BVdb publication page

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Mapping the p53 transcriptome universe using p53 natural polymorphs.

Cell Death And Differentiation

Wang, B B; Niu, D D; Lam, T H TH; Xiao, Z Z; Ren, E C EC

Publication Date: 2014-04

Variant appearance in text: p53: S366A

PubMed Link: 24076587

Variant Present in the following documents:

• Main text

View BVdb publication page

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: TP53: S366A

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

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Mechanistic differences in the transcriptional activation of p53 by 14-3-3 isoforms.

Nucleic Acids Research

Rajagopalan, Sridharan S; Sade, Robert S RS; Townsley, Fiona M FM; Fersht, Alan R AR

Publication Date: 2010-01

Variant appearance in text: p53: S366A

PubMed Link: 19933256

Variant Present in the following documents:

• Main text

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Degradation of phosphorylated p53 by viral protein-ECS E3 ligase complex.

Plos Pathogens

Sato, Yoshitaka Y; Kamura, Takumi T; Shirata, Noriko N; Murata, Takayuki T; Kudoh, Ayumi A; Iwahori, Satoko S; Nakayama, Sanae S; Isomura, Hiroki H; Nishiyama, Yukihiro Y; Tsurumi, Tatsuya T

Publication Date: 2009-07

Variant appearance in text: p53: S366A

PubMed Link: 19649319

Variant Present in the following documents:

• Main text

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Genome-wide analysis to predict protein sequence variations that change phosphorylation sites or their corresponding kinases.

Nucleic Acids Research

Ryu, Gil-Mi GM; Song, Pamela P; Kim, Kyu-Won KW; Oh, Kyung-Soo KS; Park, Keun-Joon KJ; Kim, Jong Hun JH

Publication Date: 2009-03

Variant appearance in text: TP53: S366A

PubMed Link: 19139070

Variant Present in the following documents:

• Main text
• gkn1008_nar-01723-s-2008-File011.xls, sheet 3
• gkn1008_nar-01723-s-2008-File011.xls, sheet 1
• gkn1008.pdf
• gkn1008_nar-01723-s-2008-File006.xls, sheet 1
• gkn1008_nar-01723-s-2008-File008.xls, sheet 1
• gkn1008_nar-01723-s-2008-File009.xls, sheet 1

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p53 C-terminal phosphorylation by CHK1 and CHK2 participates in the regulation of DNA-damage-induced C-terminal acetylation.

Molecular Biology Of The Cell

Ou, Yi-Hung YH; Chung, Pei-Han PH; Sun, Te-Ping TP; Shieh, Sheau-Yann SY

Publication Date: 2005-04

Variant appearance in text: p53: S366A

PubMed Link: 15659650

Variant Present in the following documents:

• Main text

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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1.

Molecular And Cellular Biology

Zhao, H H; Piwnica-Worms, H H

Publication Date: 2001-07

Variant appearance in text: p53: S366A

PubMed Link: 11390642

Variant Present in the following documents:

• Main text

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