TP53 c.1034A>G ;(p.N345S)

Variant ID: 17-7573993-T-C

NM_000546.5(TP53):c.1034A>G;(p.N345S)

This variant was identified in 10 publications

View GRCh38 version.




Publications:


Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis.

Clinical And Translational Gastroenterology
Cowan, Robert W RW; Pratt, Erica D ED; Kang, Jin Muk JM; Zhao, Jun J; Wilhelm, Joshua J JJ; Abdulla, Muhamad M; Qiao, Edmund M EM; Brennan, Luke P LP; Ulintz, Peter J PJ; Bellin, Melena D MD; Rhim, Andrew D AD
Publication Date: 2021-11-18

Variant appearance in text: TP53: 1034A>G; Asn345Ser
PubMed Link: 34797250
Variant Present in the following documents:
  • ct9-12-e00431-s006.xlsx, sheet 1
  • ct9-12-e00431-s005.xlsx, sheet 1
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: TP53: N345S
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



appreci8: a pipeline for precise variant calling integrating 8 tools.

Bioinformatics (Oxford, England)
Sandmann, Sarah S; Karimi, Mohsen M; de Graaf, Aniek O AO; Rohde, Christian C; Göllner, Stefanie S; Varghese, Julian J; Ernsting, Jan J; Walldin, Gunilla G; van der Reijden, Bert A BA; Müller-Tidow, Carsten C; Malcovati, Luca L; Hellström-Lindberg, Eva E; Jansen, Joop H JH; Dugas, Martin M
Publication Date: 2018-12-15

Variant appearance in text: TP53: 1034A>G; Asn345Ser
PubMed Link: 29945233
Variant Present in the following documents:
  • bty518_supplementary_data_s6.xlsx, sheet 8
View BVdb publication page



Germ-line and somatic EPHA2 coding variants in lens aging and cataract.

Plos One
Bennett, Thomas M TM; M'Hamdi, Oussama O; Hejtmancik, J Fielding JF; Shiels, Alan A
Publication Date: 2017

Variant appearance in text: TP53: N345S
PubMed Link: 29267365
Variant Present in the following documents:
  • pone.0189881.s008.xlsx, sheet 1
View BVdb publication page



Synergistic activity and heterogeneous acquired resistance of combined MDM2 and MEK inhibition in KRAS mutant cancers.

Oncogene
Hata, A N AN; Rowley, S S; Archibald, H L HL; Gomez-Caraballo, M M; Siddiqui, F M FM; Ji, F F; Jung, J J; Light, M M; Lee, J S JS; Debussche, L L; Sidhu, S S; Sadreyev, R I RI; Watters, J J; Engelman, J A JA
Publication Date: 2017-11-23

Variant appearance in text: TP53: N345S
PubMed Link: 28783173
Variant Present in the following documents:
  • Main text
  • nihms888473.pdf
  • NIHMS888473-supplement-1.pdf
View BVdb publication page



Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells.

Oncotarget
Menendez, Daniel D; Lowe, Julie M JM; Snipe, Joyce J; Resnick, Michael A MA
Publication Date: 2016-09-20

Variant appearance in text: p53: N345S
PubMed Link: 27533082
Variant Present in the following documents:
  • oncotarget-07-61630-s001.pdf
View BVdb publication page



iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: N345S
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
View BVdb publication page



Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: TP53: N345S
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Menendez, Daniel D; Inga, Alberto A; Resnick, Michael A MA
Publication Date: 2010-01-26

Variant appearance in text: p53: N345S
PubMed Link: 20080630
Variant Present in the following documents:
  • Main text
View BVdb publication page



Noncanonical DNA motifs as transactivation targets by wild type and mutant p53.

Plos Genetics
Jordan, Jennifer J JJ; Menendez, Daniel D; Inga, Alberto A; Noureddine, Maher M; Nourredine, Maher M; Bell, Douglas A DA; Bell, Douglas D; Resnick, Michael A MA
Publication Date: 2008-06-27

Variant appearance in text: p53: N345S
PubMed Link: 18714371
Variant Present in the following documents:
  • Main text
View BVdb publication page