TP53 c.1009_1010delinsGC ;(p.R337A)

Variant ID: 17-7574017-CG-GC

NM_000546.5(TP53):c.1009_1010delinsGC;(p.R337A)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Interactions of p53 with poly(ADP-ribose) and DNA induce distinct changes in protein structure as revealed by ATR-FTIR spectroscopy.

Nucleic Acids Research
Krüger, Annika A; Stier, Anna A; Fischbach, Arthur A; Bürkle, Alexander A; Hauser, Karin K; Mangerich, Aswin A
Publication Date: 2019-05-21

Variant appearance in text: p53: R337A
PubMed Link: 30892621
Variant Present in the following documents:
  • Main text
  • gkz175.pdf
View BVdb publication page



Nitration of the tumor suppressor protein p53 at tyrosine 327 promotes p53 oligomerization and activation.

Biochemistry
Yakovlev, Vasily A VA; Bayden, Alexander S AS; Graves, Paul R PR; Kellogg, Glen E GE; Mikkelsen, Ross B RB
Publication Date: 2010-06-29

Variant appearance in text: p53: Arg337Ala
PubMed Link: 20499882
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Cdc14B-Cdh1-Plk1 axis controls the G2 DNA-damage-response checkpoint.

Cell
Bassermann, Florian F; Frescas, David D; Guardavaccaro, Daniele D; Busino, Luca L; Peschiaroli, Angelo A; Pagano, Michele M
Publication Date: 2008-07-25

Variant appearance in text: p53: R337A
PubMed Link: 18662541
Variant Present in the following documents:
  • Main text
View BVdb publication page



Disruption of an intermonomer salt bridge in the p53 tetramerization domain results in an increased propensity to form amyloid fibrils.

Protein Science : A Publication Of The Protein Society
Galea, Charles C; Bowman, Prentice P; Kriwacki, Richard W RW
Publication Date: 2005-12

Variant appearance in text: p53: R337A
PubMed Link: 16260757
Variant Present in the following documents:
  • Main text
View BVdb publication page