Aberrant phase separation and nucleolar dysfunction in rare genetic diseases.
Nature
Mensah, Martin A MA; Niskanen, Henri H; Magalhaes, Alexandre P AP; Basu, Shaon S; Kircher, Martin M; Sczakiel, Henrike L HL; Reiter, Alisa M V AMV; Elsner, Jonas J; Meinecke, Peter P; Biskup, Saskia S; Chung, Brian H Y BHY; Dombrowsky, Gregor G; Eckmann-Scholz, Christel C; Hitz, Marc Phillip MP; Hoischen, Alexander A; Holterhus, Paul-Martin PM; Hülsemann, Wiebke W; Kahrizi, Kimia K; Kalscheuer, Vera M VM; Kan, Anita A; Krumbiegel, Mandy M; Kurth, Ingo I; Leubner, Jonas J; Longardt, Ann Carolin AC; Moritz, Jörg D JD; Najmabadi, Hossein H; Skipalova, Karolina K; Snijders Blok, Lot L; Tzschach, Andreas A; Wiedersberg, Eberhard E; Zenker, Martin M; Garcia-Cabau, Carla C; Buschow, René R; Salvatella, Xavier X; Kraushar, Matthew L ML; Mundlos, Stefan S; Caliebe, Almuth A; Spielmann, Malte M; Horn, Denise D; Hnisz, Denes D
Publication Date: 2023-02-08
Variant appearance in text: TP53: 925C>T; Pro309Ser
Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRα1, in intestinal lesions.
Molecular Oncology
Giolito, Maria Virginia MV; La Rosa, Théo T; Farhat, Diana D; Bodoirat, Serguei S; Guardia, Gabriela D A GDA; Domon-Dell, Claire C; Galante, Pedro A F PAF; Freund, Jean-Noel JN; Plateroti, Michelina M
p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis.
Nature Communications
Solé, Laura L; Lobo-Jarne, Teresa T; Álvarez-Villanueva, Daniel D; Alonso-Marañón, Josune J; Guillén, Yolanda Y; Guix, Marta M; Sangrador, Irene I; Rozalén, Catalina C; Vert, Anna A; Barbachano, Antonio A; Lop, Joan J; Salido, Marta M; Bellosillo, Beatriz B; García-Romero, Raquel R; Garrido, Marta M; González, Jessica J; Martínez-Iniesta, María M; López-Arribillaga, Erika E; Salazar, Ramón R; Montagut, Clara C; Torres, Ferrán F; Iglesias, Mar M; Celià-Terrassa, Toni T; Muñoz, Alberto A; Villanueva, Alberto A; Bigas, Anna A; Espinosa, Lluís L
Suppressive effect of α-mangostin for cancer stem cells in colorectal cancer via the Notch pathway.
Bmc Cancer
Jo, Min Kyoung MK; Moon, Chang Mo CM; Kim, Eun Ju EJ; Kwon, Ji-Hee JH; Fei, Xiang X; Kim, Seong-Eun SE; Jung, Sung-Ae SA; Kim, Minsuk M; Mun, Yeung-Chul YC; Ahn, Young-Ho YH; Seo, Seung-Yong SY; Kim, Tae Il TI
Regulation of miRNAs Expression by Mutant p53 Gain of Function in Cancer.
Frontiers In Cell And Developmental Biology
Madrigal, Tzitzijanik T; Hernández-Monge, Jesús J; Herrera, Luis A LA; González-De la Rosa, Claudia Haydée CH; Domínguez-Gómez, Guadalupe G; Candelaria, Myrna M; Luna-Maldonado, Fernando F; Calderón González, Karla G KG; Díaz-Chávez, José J
Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells.
Ebiomedicine
Le, Hillary H HH; Cinaroglu, Suleyman S SS; Manalo, Elise C EC; Ors, Aysegul A; Gomes, Michelle M MM; Duan Sahbaz, Burcin B; Bonic, Karla K; Origel Marmolejo, Carlos A CA; Quentel, Arnaud A; Plaut, Justin S JS; Kawashima, Taryn E TE; Ozdemir, E Sila ES; Malhotra, Sanjay V SV; Ahiska, Yavuz Y; Sezerman, Ugur U; Bayram Akcapinar, Gunseli G; Saldivar, Joshua C JC; Timucin, Emel E; Fischer, Jared M JM
Protein mimetic amyloid inhibitor potently abrogates cancer-associated mutant p53 aggregation and restores tumor suppressor function.
Nature Communications
Palanikumar, L L; Karpauskaite, Laura L; Al-Sayegh, Mohamed M; Chehade, Ibrahim I; Alam, Maheen M; Hassan, Sarah S; Maity, Debabrata D; Ali, Liaqat L; Kalmouni, Mona M; Hunashal, Yamanappa Y; Ahmed, Jemil J; Houhou, Tatiana T; Karapetyan, Shake S; Falls, Zackary Z; Samudrala, Ram R; Pasricha, Renu R; Esposito, Gennaro G; Afzal, Ahmed J AJ; Hamilton, Andrew D AD; Kumar, Sunil S; Magzoub, Mazin M
Thomson, Jason J; Bewicke-Copley, Findlay F; Anene, Chinedu Anthony CA; Gulati, Abha A; Nagano, Ai A; Purdie, Karin K; Inman, Gareth J GJ; Proby, Charlotte M CM; Leigh, Irene M IM; Harwood, Catherine A CA; Wang, Jun J
TP53 Mutation Analysis in Gastric Cancer and Clinical Outcomes of Patients with Metastatic Disease Treated with Ramucirumab/Paclitaxel or Standard Chemotherapy.
Cancers
Graziano, Francesco F; Fischer, Nicholas W NW; Bagaloni, Irene I; Di Bartolomeo, Maria M; Lonardi, Sara S; Vincenzi, Bruno B; Perrone, Giuseppe G; Fornaro, Lorenzo L; Ongaro, Elena E; Aprile, Giuseppe G; Bisonni, Renato R; Prisciandaro, Michele M; Malkin, David D; Gariépy, Jean J; Fassan, Matteo M; Loupakis, Fotios F; Sarti, Donatella D; Del Prete, Michela M; Catalano, Vincenzo V; Alessandroni, Paolo P; Magnani, Mauro M; Ruzzo, Annamaria A
Differences in the molecular profile of endometrial cancers from British White and British South Asian women.
Plos One
Polymeros, Konstantinos K; Guttery, David S DS; Hew, Roger R; Bishop, Rachael R; Stannard, Elizabeth E; Macip, Salvador S; Symonds, Paul P; Moss, Esther L EL
Proteomic Characterization of Colorectal Cancer Cells versus Normal-Derived Colon Mucosa Cells: Approaching Identification of Novel Diagnostic Protein Biomarkers in Colorectal Cancer.
International Journal Of Molecular Sciences
Ludvigsen, Maja M; Thorlacius-Ussing, Louise L; Vorum, Henrik H; Moyer, Mary Pat MP; Stender, Mogens Tornby MT; Thorlacius-Ussing, Ole O; Honoré, Bent B
Xanthohumol, a Prenylated Flavonoid from Hops, Induces DNA Damages in Colorectal Cancer Cells and Sensitizes SW480 Cells to the SN38 Chemotherapeutic Agent.
Sourcing the immune system to induce immunogenic cell death in Kras-colorectal cancer cells.
British Journal Of Cancer
Cirone, Mara M; Lotti, Lavinia Vittoria LV; Granato, Marisa M; Renzo, Livia Di LD; Biunno, Ida I; Cattaneo, Monica M; Verginelli, Fabio F; Vespa, Simone S; Davies, Derek D; Wells, Valerie V; Mariani-Costantini, Renato R; Mallucci, Livio L
False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases.
Plos One
Kim, Young-Ho YH; Song, Yura Y; Kim, Jong-Kwang JK; Kim, Tae-Min TM; Sim, Hye Won HW; Kim, Hyung-Lae HL; Jang, Hyonchol H; Kim, Young-Woo YW; Hong, Kyeong-Man KM