TP53 c.913_914delinsGC ;(p.K305A)

Variant ID: 17-7577024-TT-GC

NM_000546.5(TP53):c.913_914delinsGC;(p.K305A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNAInduced Silencing of NF-κB-Inducing Kinase.

Molecules And Cells
Jang, Hanbit H; Park, Seulki S; Kim, Jaehoon J; Kim, Jong Hwan JH; Kim, Seon-Young SY; Cho, Sayeon S; Park, Sung Goo SG; Park, Byoung Chul BC; Kim, Sunhong S; Kim, Jeong-Hoon JH
Publication Date: 2020-01-31

Variant appearance in text: p53: K305A
PubMed Link: 31870133
Variant Present in the following documents:
  • Main text
  • molce-43-023.pdf
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p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance.

Oncogene
Zhang, Jixiang J; Tan, Peng P; Guo, Lei L; Gong, Jing J; Ma, Jingjing J; Li, Jia J; Lee, Minjung M; Fang, Shaohai S; Jing, Ji J; Johnson, Gavin G; Sun, Deqiang D; Cao, Wen-Ming WM; Dashwood, Roderick R; Han, Leng L; Zhou, Yubin Y; Dong, Wei-Guo WG; Huang, Yun Y
Publication Date: 2019-03

Variant appearance in text: p53: K305A
PubMed Link: 30390073
Variant Present in the following documents:
  • Main text
  • nihms-1501648.pdf
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Wild-type p53 oligomerizes more efficiently than p53 hot-spot mutants and overcomes mutant p53 gain-of-function via a "dominant-positive" mechanism.

Oncotarget
Walerych, Dawid D; Pruszko, Magdalena M; Zyla, Lukasz L; Wezyk, Michalina M; Gaweda-Walerych, Katarzyna K; Zylicz, Alicja A
Publication Date: 2018-08-10

Variant appearance in text: p53: K305A
PubMed Link: 30174797
Variant Present in the following documents:
  • Main text
  • oncotarget-09-32063.pdf
View BVdb publication page



p53-mediated activation of the mitochondrial protease HtrA2/Omi prevents cell invasion.

The Journal Of Cell Biology
Yamauchi, Shota S; Hou, Yan Yan YY; Guo, Alvin Kunyao AK; Hirata, Hiroaki H; Nakajima, Wataru W; Yip, Ai Kia AK; Yu, Cheng-han CH; Harada, Ichiro I; Chiam, Keng-Hwee KH; Sawada, Yasuhiro Y; Tanaka, Nobuyuki N; Kawauchi, Keiko K
Publication Date: 2014-03-31

Variant appearance in text: p53: K305A
PubMed Link: 24662565
Variant Present in the following documents:
  • Main text
  • JCB_201309107.pdf
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High mitochondrial priming sensitizes hESCs to DNA-damage-induced apoptosis.

Cell Stem Cell
Liu, Julia C JC; Guan, Xiao X; Ryan, Jeremy A JA; Rivera, Ana G AG; Mock, Caroline C; Agrawal, Vishesh V; Agarwal, Vishesh V; Letai, Anthony A; Lerou, Paul H PH; Lahav, Galit G
Publication Date: 2013-10-03

Variant appearance in text: p53: K305A
PubMed Link: 23954752
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mechanistic studies of MDM2-mediated ubiquitination in p53 regulation.

The Journal Of Biological Chemistry
Brooks, Christopher L CL; Li, Muyang M; Gu, Wei W
Publication Date: 2007-08-03

Variant appearance in text: p53: K305A
PubMed Link: 17500067
Variant Present in the following documents:
  • Main text
View BVdb publication page