Publications:

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Paclitaxel and cisplatin with or without cetuximab in metastatic esophageal squamous cell carcinoma: a randomized, multicenter phase II trial.

Innovation (Cambridge (Mass.))

Lu, Zhihao Z; Zhang, Yanqiao Y; Fan, Qingxia Q; Pan, Yueyin Y; Jiang, Da D; Lu, Ping P; Zhang, Jingdong J; Yuan, Xianglin X; Feng, Jifeng J; Yang, Shujun S; Yue, Wenbin W; Zhao, Lin L; Xu, Yunhua Y; Luo, Jinhua J; Shen, Lin L

Publication Date: 2022-05-10

Variant appearance in text: TP53: 851C>G; T284R

PubMed Link: 35509869

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

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Distinct mechanisms control genome recognition by p53 at its target genes linked to different cell fates.

Nature Communications

Farkas, Marina M; Hashimoto, Hideharu H; Bi, Yingtao Y; Davuluri, Ramana V RV; Resnick-Silverman, Lois L; Manfredi, James J JJ; Debler, Erik W EW; McMahon, Steven B SB

Publication Date: 2021-01-20

Variant appearance in text: p53: T284R

PubMed Link: 33473123

Variant Present in the following documents:

• 41467_2020_20783_MOESM1_ESM.pdf

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: TP53: T284R

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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Roles of computational modelling in understanding p53 structure, biology, and its therapeutic targeting.

Journal Of Molecular Cell Biology

Tan, Yaw Sing YS; Mhoumadi, Yasmina Y; Verma, Chandra S CS

Publication Date: 2019-04-01

Variant appearance in text: p53: T284R

PubMed Link: 30726928

Variant Present in the following documents:

• mjz009.pdf

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In silico identification of rescue sites by double force scanning.

Bioinformatics (Oxford, England)

Tiberti, Matteo M; Pandini, Alessandro A; Fraternali, Franca F; Fornili, Arianna A

Publication Date: 2018-01-15

Variant appearance in text: p53: T284R

PubMed Link: 28961796

Variant Present in the following documents:

• Main text
• btx515.pdf

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: T284R

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

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Structure and Function of p53-DNA Complexes with Inactivation and Rescue Mutations: A Molecular Dynamics Simulation Study.

Plos One

Kamaraj, Balu B; Bogaerts, Annemie A

Publication Date: 2015

Variant appearance in text: p53: T284R

PubMed Link: 26244575

Variant Present in the following documents:

• Main text
• pone.0134638.pdf

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: T284R

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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Structures of oncogenic, suppressor and rescued p53 core-domain variants: mechanisms of mutant p53 rescue.

Acta Crystallographica. Section D, Biological Crystallography

Wallentine, Brad D BD; Wang, Ying Y; Tretyachenko-Ladokhina, Vira V; Tan, Martha M; Senear, Donald F DF; Luecke, Hartmut H

Publication Date: 2013-10

Variant appearance in text: p53: T284R

PubMed Link: 24100332

Variant Present in the following documents:

• Main text

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Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions.

Nucleic Acids Research

Eldar, Amir A; Rozenberg, Haim H; Diskin-Posner, Yael Y; Rohs, Remo R; Shakked, Zippora Z

Publication Date: 2013-10

Variant appearance in text: p53: T284R

PubMed Link: 23863845

Variant Present in the following documents:

• Main text
• gkt630.pdf
• supp_gkt630_gkt630_suppl_data_July14.pdf

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Molecular mechanisms of functional rescue mediated by P53 tumor suppressor mutations.

Biophysical Chemistry

Tan, Yu-Hong YH; Chen, Y Morris YM; Ye, Xiang X; Lu, Qiang Q; Tretyachenko-Ladokhina, Vira V; Yang, Wei W; Senear, Donald F DF; Luo, Ray R

Publication Date: 2009-11

Variant appearance in text: p53: T284R

PubMed Link: 19748724

Variant Present in the following documents:

• Main text

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