TP53 c.839G>C ;(p.R280T)

Variant ID: 17-7577099-C-G

NM_000546.5(TP53):c.839G>C;(p.R280T)

This variant was identified in 247 publications

View GRCh38 version.




Publications:


The Competition of Yin and Yang: Exploring the Role of Wild-Type and Mutant p53 in Tumor Progression.

Biomedicines
Cai, Bi-He BH; Sung, Yu-Te YT; Chen, Chia-Chi CC; Shaw, Jei-Fu JF; Hsin, I-Lun IL
Publication Date: 2023-04-17

Variant appearance in text: p53: R280T
PubMed Link: 37189810
Variant Present in the following documents:
  • biomedicines-11-01192.pdf
View BVdb publication page



Surveillance of cfDNA Hot Spot Mutations in NSCLC Patients during Disease Progression.

International Journal Of Molecular Sciences
Sestokaite, Agne A; Gedvilaite, Vaida V; Cicenas, Saulius S; Sabaliauskaite, Rasa R; Jarmalaite, Sonata S
Publication Date: 2023-04-09

Variant appearance in text: TP53: R280T
PubMed Link: 37108122
Variant Present in the following documents:
  • Main text
  • ijms-24-06958.pdf
View BVdb publication page



Utilizing cell-free DNA to predict risk of developing brain metastases in patients with metastatic breast cancer.

Npj Breast Cancer
Vidula, Neelima N; Niemierko, Andrzej A; Hesler, Katherine K; Ryan, Lianne L; Moy, Beverly B; Isakoff, Steven S; Ellisen, Leif L; Juric, Dejan D; Bardia, Aditya A
Publication Date: 2023-04-19

Variant appearance in text: TP53: R280T
PubMed Link: 37076495
Variant Present in the following documents:
  • 41523_2023_528_MOESM1_ESM.pdf
View BVdb publication page



Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: TP53: R280T
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
View BVdb publication page



Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation.

Nature Communications
Xu, An A; Liu, Mo M; Huang, Mo-Fan MF; Zhang, Yang Y; Hu, Ruifeng R; Gingold, Julian A JA; Liu, Ying Y; Zhu, Dandan D; Chien, Chian-Shiu CS; Wang, Wei-Chen WC; Liao, Zian Z; Yuan, Fei F; Hsu, Chih-Wei CW; Tu, Jian J; Yu, Yao Y; Rosen, Taylor T; Xiong, Feng F; Jia, Peilin P; Yang, Yi-Ping YP; Bazer, Danielle A DA; Chen, Ya-Wen YW; Li, Wenbo W; Huff, Chad D CD; Zhu, Jay-Jiguang JJ; Aguilo, Francesca F; Chiou, Shih-Hwa SH; Boles, Nathan C NC; Lai, Chien-Chen CC; Hung, Mien-Chie MC; Zhao, Zhongming Z; Van Nostrand, Eric L EL; Zhao, Ruiying R; Lee, Dung-Fang DF
Publication Date: 2023-03-27

Variant appearance in text: p53: R280T
PubMed Link: 36973285
Variant Present in the following documents:
  • Main text
  • 41467_2023_Article_37398.pdf
  • 41467_2023_37398_MOESM1_ESM.pdf
View BVdb publication page



Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types.

Scientific Reports
Sasaki, Keiju K; Takahashi, Shin S; Ouchi, Kota K; Otsuki, Yasufumi Y; Wakayama, Shonosuke S; Ishioka, Chikashi C
Publication Date: 2023-03-24

Variant appearance in text: TP53: R280T
PubMed Link: 36964217
Variant Present in the following documents:
  • 41598_2023_32092_MOESM1_ESM.xlsx, sheet 4
View BVdb publication page



A Phase II Trial of Guadecitabine plus Atezolizumab in Metastatic Urothelial Carcinoma Progressing after Initial Immune Checkpoint Inhibitor Therapy.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Jang, H Josh HJ; Hostetter, Galen G; MacFarlane, Alexander W AW; Madaj, Zachary Z; Ross, Eric A EA; Hinoue, Toshinori T; Kulchycki, Justin R JR; Burgos, Ryan S RS; Tafseer, Mahvish M; Alpaugh, R Katherine RK; Schwebel, Candice L CL; Kokate, Rutika R; Geynisman, Daniel M DM; Zibelman, Matthew R MR; Ghatalia, Pooja P; Nichols, Peter W PW; Chung, Woonbok W; Madzo, Jozef J; Hahn, Noah M NM; Quinn, David I DI; Issa, Jean-Pierre J JJ; Topper, Michael J MJ; Baylin, Stephen B SB; Shen, Hui H; Campbell, Kerry S KS; Jones, Peter A PA; Plimack, Elizabeth R ER
Publication Date: 2023-03-16

Variant appearance in text: TP53: R280T
PubMed Link: 36928921
Variant Present in the following documents:
  • ccr-22-3642_supplementary_tables_1_suppts1.xlsx, sheet 3
View BVdb publication page



Pan-cancer clinical impact of latent drivers from double mutations.

Communications Biology
Yavuz, Bengi Ruken BR; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Tuncbag, Nurcan N
Publication Date: 2023-02-20

Variant appearance in text: TP53: R280T
PubMed Link: 36808143
Variant Present in the following documents:
  • 42003_2023_4519_MOESM3_ESM.xlsx, sheet 3
View BVdb publication page



Clinical impact of TP53 disruption in chronic lymphocytic leukemia patients treated with ibrutinib: a campus CLL study.

Leukemia
Bomben, Riccardo R; Rossi, Francesca Maria FM; Vit, Filippo F; Bittolo, Tamara T; Zucchetto, Antonella A; Papotti, Robel R; Tissino, Erika E; Pozzo, Federico F; Degan, Massimo M; Polesel, Jerry J; Bulian, Pietro P; Marasca, Roberto R; Reda, Gianluigi G; Laurenti, Luca L; Olivieri, Jacopo J; Chiarenza, Annalisa A; Laureana, Roberta R; Postorino, Massimiliano M; Del Principe, Maria Ilaria MI; Cuneo, Antonio A; Gentile, Massimo M; Morabito, Fortunato F; Fronza, Gilberto G; Tafuri, Agostino A; Zaja, Francesco F; Foà, Robin R; Di Raimondo, Francesco F; Del Poeta, Giovanni G; Gattei, Valter V
Publication Date: 2023-02-18

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 36807650
Variant Present in the following documents:
  • 41375_2023_1845_MOESM1_ESM.pdf
View BVdb publication page



Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications
Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI
Publication Date: 2023-02-08

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 36755027
Variant Present in the following documents:
  • 41467_2023_36328_MOESM7_ESM.xlsx, sheet 1
  • 41467_2023_36328_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Genomic complexity predicts resistance to endocrine therapy and CDK4/6 inhibition in hormone receptor-positive (HR+)/HER2-negative metastatic breast cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Davis, Andrew A AA; Luo, Jingqin J; Zheng, Tiantian T; Dai, Chao C; Dong, Xiaoxi X; Tan, Lu L; Suresh, Rama R; Ademuyiwa, Foluso O FO; Rigden, Caron C; Rearden, Timothy P TP; Clifton, Katherine K; Weilbaecher, Katherine K; Frith, Ashley A; Tandra, Pavankumar K PK; Summa, Tracy T; Haas, Brittney B; Thomas, Shana S; Hernandez-Aya, Leonel F LF; Peterson, Lindsay L LL; Wang, Xiaohong X; Luo, Shujun J SJ; Zhou, Kemin K; Du, Pan P; Jia, Shidong S; King, Bonnie L BL; Krishnamurthy, Jairam J; Ma, Cynthia X CX
Publication Date: 2023-01-24

Variant appearance in text: TP53: 839G>C; Arg280Thr
PubMed Link: 36693175
Variant Present in the following documents:
  • ccr-22-2177_supplementary_data_s1_suppds1.xlsx, sheet 3
View BVdb publication page



Clinical sequencing identifies potential actionable alterations in a high rate of urachal and primary bladder adenocarcinomas.

Cancer Medicine
Varadi, Melinda M; Nagy, Nikolett N; Reis, Henning H; Hadaschik, Boris B; Niedworok, Christian C; Modos, Orsolya O; Szendroi, Attila A; Ablat, Jason J; Black, Peter C PC; Keresztes, David D; Csizmarik, Anita A; Olah, Csilla C; Gaisa, Nadine T NT; Kiss, Andras A; Timar, Jozsef J; Toth, Erika E; Csernak, Erzsebet E; Gerstner, Arpad A; Mittal, Vinay V; Karkampouna, Sofia S; Kruithof de Julio, Marianna M; Gyorffy, Balazs B; Bedics, Gabor G; Rink, Michael M; Fisch, Margit M; Nyirady, Peter P; Szarvas, Tibor T
Publication Date: 2023-01-20

Variant appearance in text: TP53: Arg280Thr
PubMed Link: 36670542
Variant Present in the following documents:
  • CAM4-12-9041-s001.xlsx, sheet 2
  • CAM4-12-9041-s001.xlsx, sheet 1
View BVdb publication page



Immunogenomic analysis of human brain metastases reveals diverse immune landscapes across genetically distinct tumors.

Cell Reports. Medicine
Álvarez-Prado, Ángel F ÁF; Maas, Roeltje R RR; Soukup, Klara K; Klemm, Florian F; Kornete, Mara M; Krebs, Fanny S FS; Zoete, Vincent V; Berezowska, Sabina S; Brouland, Jean-Philippe JP; Hottinger, Andreas F AF; Daniel, Roy T RT; Hegi, Monika E ME; Joyce, Johanna A JA
Publication Date: 2023-01-17

Variant appearance in text: TP53: R280T
PubMed Link: 36652909
Variant Present in the following documents:
  • mmc3.xlsx, sheet 31
View BVdb publication page



Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: TP53: R280T
PubMed Link: 36561320
Variant Present in the following documents:
  • Main text
  • Table3.xlsx, sheet 1
  • Table2.xlsx, sheet 7
  • fgene-13-1071352.pdf
View BVdb publication page



An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology
Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y
Publication Date: 2022

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 36505399
Variant Present in the following documents:
  • Table_2.xlsx, sheet 3
  • Table_2.xlsx, sheet 2
View BVdb publication page



Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications
Boström, Martin M; Larsson, Erik E
Publication Date: 2022-11-17

Variant appearance in text: TP53: R280T
PubMed Link: 36396655
Variant Present in the following documents:
  • 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Comprehensive clinicopathological and genomic profiling of gallbladder cancer reveals actionable targets in half of patients.

Npj Precision Oncology
de Bitter, Tessa J J TJJ; de Reuver, Philip R PR; de Savornin Lohman, Elise A J EAJ; Kroeze, Leonie I LI; Vink-Börger, Marianne E ME; van Vliet, Shannon S; Simmer, Femke F; von Rhein, Daniel D; Jansen, Erik A M EAM; Verheij, Joanne J; van Herpen, Carla M L CML; Nagtegaal, Iris D ID; Ligtenberg, Marjolijn J L MJL; van der Post, Rachel S RS
Publication Date: 2022-11-05

Variant appearance in text: TP53: 839G>C; Arg280Thr
PubMed Link: 36335173
Variant Present in the following documents:
  • 41698_2022_327_MOESM2_ESM.xlsx, sheet 3
View BVdb publication page



Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics
Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q
Publication Date: 2022-11-04

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 36333792
Variant Present in the following documents:
  • 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Omics analyses of a somatic <i>Trp53<sup>R245W/+</sup></i> breast cancer model identify cooperating driver events activating PI3K/AKT/mTOR signaling.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Yu, Xiaojie X; Zhang, Yun Y; Xiong, Shunbin S; McDaniel, Joy M JM; Sun, Chang C; Chau, Gilda P GP; Gencel-Augusto, Jovanka J; Chachad, Dhruv D; Morrissey, Rhiannon L RL; Rao, Xiayu X; Wang, Jing J; Lozano, Guillermina G
Publication Date: 2022-11-08

Variant appearance in text: p53: R280T
PubMed Link: 36322759
Variant Present in the following documents:
  • pnas.2210618119.sapp.pdf
View BVdb publication page



Heterogeneity of the cancer cell line metabolic landscape.

Molecular Systems Biology
Shorthouse, David D; Bradley, Jenna J; Critchlow, Susan E SE; Bendtsen, Claus C; Hall, Benjamin A BA
Publication Date: 2022-11

Variant appearance in text: TP53: 839G>C; Arg280Thr
PubMed Link: 36321551
Variant Present in the following documents:
  • MSB-18-e11006-s010.xlsx, sheet 1
View BVdb publication page



The synthetic lethality of targeting cell cycle checkpoints and PARPs in cancer treatment.

Journal Of Hematology & Oncology
Li, Shuangying S; Wang, Liangliang L; Wang, Yuanyuan Y; Zhang, Changyi C; Hong, Zhenya Z; Han, Zhiqiang Z
Publication Date: 2022-10-17

Variant appearance in text: TP53: R280T
PubMed Link: 36253861
Variant Present in the following documents:
  • Main text
  • 13045_2022_Article_1360.pdf
View BVdb publication page



Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms.

Frontiers In Immunology
Liu, Zhichao Z; Lin, Guo G; Yan, Zeping Z; Li, Linduo L; Wu, Xingchen X; Shi, Jingrong J; He, Jianxing J; Zhao, Lei L; Liang, Hengrui H; Wang, Wei W
Publication Date: 2022

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 36238300
Variant Present in the following documents:
  • Table_1.xlsx, sheet 4
View BVdb publication page



A transcriptional network of cell cycle dysregulation in noninvasive papillary urothelial carcinoma.

Scientific Reports
Warrick, Joshua I JI; Knowles, Margaret A MA; Hurst, Carolyn D CD; Shuman, Lauren L; Raman, Jay D JD; Walter, Vonn V; Putt, Jeffrey J; Dyrskjøt, Lars L; Groeneveld, Clarice C; Castro, Mauro A A MAA; Robertson, A Gordon AG; DeGraff, David J DJ
Publication Date: 2022-10-03

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 36192513
Variant Present in the following documents:
  • 41598_2022_20927_MOESM14_ESM.xlsx, sheet 1
View BVdb publication page



New methodology of TMB assessment from tissue and liquid biopsy in NSCLC.

Plos One
Křížová, Ľudmila Ľ; Šafaříková, Markéta M; Kalousová, Marta M; Pfeiferová, Lucie L; Kuběna, Aleš Antonín AA; Vočka, Michal M; Ulrych, Jan J; Franková, Věra V; Petruželka, Luboš L; Zima, Tomáš T; Feltl, David D
Publication Date: 2022

Variant appearance in text: TP53: 782+400G>C; Arg280Thr; rs121912660
PubMed Link: 36155654
Variant Present in the following documents:
  • pone.0275121.s002.xlsx, sheet 3
  • pone.0275121.s001.xlsx, sheet 3
View BVdb publication page



EPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers.

Bmc Pulmonary Medicine
Li, Zhenxiang Z; Zhou, Qing Q; Wang, Qi Q; Wang, Haiyong H; Yue, Weiming W
Publication Date: 2022-09-19

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 36123678
Variant Present in the following documents:
  • 12890_2022_2161_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience
Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X
Publication Date: 2022-09-16

Variant appearance in text: p53: 839G>C
PubMed Link: 36117989
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page



Shallow WGS of individual CTCs identifies actionable targets for informing treatment decisions in metastatic breast cancer.

British Journal Of Cancer
Fernandez-Garcia, Daniel D; Nteliopoulos, Georgios G; Hastings, Robert K RK; Rushton, Amelia A; Page, Karen K; Allsopp, Rebecca C RC; Ambasager, Bana B; Gleason, Kelly K; Guttery, David S DS; Ali, Simak S; Charles Coombes, R R; Shaw, Jacqueline A JA
Publication Date: 2022-11

Variant appearance in text: TP53: R280T
PubMed Link: 36088510
Variant Present in the following documents:
  • 41416_2022_1962_MOESM2_ESM.xlsx, sheet 4
  • 41416_2022_1962_MOESM2_ESM.xlsx, sheet 5
View BVdb publication page



Integrated cohort of esophageal squamous cell cancer reveals genomic features underlying clinical characteristics.

Nature Communications
Li, Minghao M; Zhang, Zicheng Z; Wang, Qianrong Q; Yi, Yan Y; Li, Baosheng B
Publication Date: 2022-09-07

Variant appearance in text: TP53: R280T
PubMed Link: 36071046
Variant Present in the following documents:
  • 41467_2022_32962_MOESM15_ESM.xlsx, sheet 22
View BVdb publication page



High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer.

Nature Communications
Palafox, Marta M; Monserrat, Laia L; Bellet, Meritxell M; Villacampa, Guillermo G; Gonzalez-Perez, Abel A; Oliveira, Mafalda M; Brasó-Maristany, Fara F; Ibrahimi, Nusaibah N; Kannan, Srinivasaraghavan S; Mina, Leonardo L; Herrera-Abreu, Maria Teresa MT; Òdena, Andreu A; Sánchez-Guixé, Mònica M; Capelán, Marta M; Azaro, Analía A; Bruna, Alejandra A; Rodríguez, Olga O; Guzmán, Marta M; Grueso, Judit J; Viaplana, Cristina C; Hernández, Javier J; Su, Faye F; Lin, Kui K; Clarke, Robert B RB; Caldas, Carlos C; Arribas, Joaquín J; Michiels, Stefan S; García-Sanz, Alicia A; Turner, Nicholas C NC; Prat, Aleix A; Nuciforo, Paolo P; Dienstmann, Rodrigo R; Verma, Chandra S CS; Lopez-Bigas, Nuria N; Scaltriti, Maurizio M; Arnedos, Monica M; Saura, Cristina C; Serra, Violeta V
Publication Date: 2022-09-07

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 36071033
Variant Present in the following documents:
  • 41467_2022_32828_MOESM4_ESM.xlsx, sheet 3
View BVdb publication page



Prognostic value of baseline genetic features and newly identified TP53 mutations in advanced breast cancer.

Molecular Oncology
Zhang, Lanxin L; Sun, Siwen S; Zhao, Xiaotian X; Liu, Jingwen J; Xu, Yang Y; Xu, Lingzhi L; Song, Chen C; Li, Na N; Yu, Jing J; Zhao, Shanshan S; Yu, Peiyao P; Fang, Fengqi F; Xie, Jiping J; Ji, Xuening X; Yu, Ruoying R; Ou, Qiuxiang Q; Zhao, Zuowei Z; Li, Man M
Publication Date: 2022-10

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 35971249
Variant Present in the following documents:
  • MOL2-16-3689-s005.xlsx, sheet 1
View BVdb publication page



Landscape of somatic alterations in large-scale solid tumors from an Asian population.

Nature Communications
Wu, Liqun L; Yao, Herui H; Chen, Hui H; Wang, Aodi A; Guo, Kun K; Gou, Wenli W; Yu, Yanfei Y; Li, Xiang X; Yao, Ming M; Yuan, Shaohua S; Pang, Fei F; Hu, Jinwei J; Chen, Lijuan L; Liu, Wenjin W; Yao, Jicheng J; Zhang, Shuirong S; Dong, Xiaowei X; Wang, Weifeng W; Hu, Jing J; Ling, Qi Q; Ding, Songming S; Wei, Yan Y; Li, Qiang Q; Cao, Weichun W; Wang, Shuang S; Di, Yang Y; Feng, Feiling F; Zhao, Gang G; Zhang, Jian J; Huang, Ling L; Xu, Jia J; Yan, Wangjun W; Tong, Zhongsheng Z; Jiang, Da D; Ji, Tao T; Li, Qiao Q; Xu, Ling L; He, Huiying H; Shang, Liang L; Liu, Jin J; Wang, Kefeng K; Wu, Duoguang D; Shen, Jingnan J; Liu, Ye Y; Zhang, Ting T; Liang, Chaojie C; Wang, Yusheng Y; Shang, Yanhong Y; Guo, Jianji J; Liang, Guanbiao G; Xu, Shifeng S; Liu, Junfeng J; Wang, Kai K; Wang, Minghui M
Publication Date: 2022-07-23

Variant appearance in text: TP53: R280T
PubMed Link: 35871175
Variant Present in the following documents:
  • 41467_2022_31780_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Spatiotemporal assessment of immunogenomic heterogeneity in multiple myeloma.

Blood Advances
Merz, Maximilian M; Hu, Qiang Q; Merz, Almuth Maria Anni AMA; Wang, Jie J; Hutson, Nicholas N; Rondeau, Cherie C; Celotto, Kimberly K; Belal, Ahmed A; Alberico, Ronald R; Block, AnneMarie A; Mohammadpour, Hemn H; Wallace, Paul K PK; Tario, Joseph D JD; Luce, Jesse J; Glenn, Sean T ST; Singh, Prashant K PK; Samur, Mehmet Kemal MK; Munshi, Nikhil C NC; Liu, Song S; McCarthy, Philip L PL; Wei, Lei L; Hillengass, Jens J
Publication Date: 2022-07-22

Variant appearance in text: TP53: R280T
PubMed Link: 35868022
Variant Present in the following documents:
  • BLOODA_ADV-2022-007457-mmc2.xlsx, sheet 1
  • main.pdf
View BVdb publication page



Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics
Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS
Publication Date: 2022-08

Variant appearance in text: TP53: R280T
PubMed Link: 35835912
Variant Present in the following documents:
  • 41588_2022_1121_MOESM3_ESM.xlsx, sheet 3
View BVdb publication page



Statins inhibit proliferation and induce apoptosis in triple-negative breast cancer cells.

Medical Oncology (Northwood, London, England)
O'Grady, Shane S; Crown, John J; Duffy, Michael J MJ
Publication Date: 2022-07-14

Variant appearance in text: p53: R280T
PubMed Link: 35834073
Variant Present in the following documents:
  • Main text
  • 12032_2022_Article_1733.pdf
View BVdb publication page



Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: TP53: 782+400G>C; R280T; rs121912660
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology
Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J
Publication Date: 2022

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 35814426
Variant Present in the following documents:
  • DataSheet_1.xlsx, sheet 2
View BVdb publication page



Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma.

The Journal Of Clinical Investigation
Lee, Patrick C PC; Klaeger, Susan S; Le, Phuong M PM; Korthauer, Keegan K; Cheng, Jingwei J; Ananthapadmanabhan, Varsha V; Frost, Thomas C TC; Stevens, Jonathan D JD; Wong, Alan Yl AY; Iorgulescu, J Bryan JB; Tarren, Anna Y AY; Chea, Vipheaviny A VA; Carulli, Isabel P IP; Lemvigh, Camilla K CK; Pedersen, Christina B CB; Gartin, Ashley K AK; Sarkizova, Siranush S; Wright, Kyle T KT; Li, Letitia W LW; Nomburg, Jason J; Li, Shuqiang S; Huang, Teddy T; Liu, Xiaoxi X; Pomerance, Lucas L; Doherty, Laura M LM; Apffel, Annie M AM; Wallace, Luke J LJ; Rachimi, Suzanna S; Felt, Kristen D KD; Wolff, Jacquelyn O JO; Witten, Elizabeth E; Zhang, Wandi W; Neuberg, Donna D; Lane, William J WJ; Zhang, Guanglan G; Olsen, Lars R LR; Thakuria, Manisha M; Rodig, Scott J SJ; Clauser, Karl R KR; Starrett, Gabriel J GJ; Doench, John G JG; Buhrlage, Sara J SJ; Carr, Steven A SA; DeCaprio, James A JA; Wu, Catherine J CJ; Keskin, Derin B DB
Publication Date: 2022-07-01

Variant appearance in text: TP53: R280T
PubMed Link: 35775490
Variant Present in the following documents:
  • jci-132-151666-s199.xlsx, sheet 1
View BVdb publication page



Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Publication Date: 2022-06-15

Variant appearance in text: TP53: R280T
PubMed Link: 35705558
Variant Present in the following documents:
  • 41467_2022_30496_MOESM2_ESM.xls, sheet 1
View BVdb publication page



Prolonged remission with pembrolizumab and radiation therapy in a patient with multisystem Langerhans cell sarcoma.

Haematologica
Zanwar, Saurabh S; Ravindran, Aishwarya A; Abeykoon, Jithma P JP; Young, Jason R JR; Kozelsky, Timothy F TF; Rech, Karen L KL; Goyal, Gaurav G; Go, Ronald S RS
Publication Date: 2022-09-01

Variant appearance in text: TP53: R280T
PubMed Link: 35615932
Variant Present in the following documents:
  • Main text
  • 1072276.pdf
View BVdb publication page



Feasibility and clinical utility of comprehensive genomic profiling of hematological malignancies.

Cancer Science
Fukuhara, Suguru S; Oshikawa-Kumade, Yuji Y; Kogure, Yasunori Y; Shingaki, Sumito S; Kariyazono, Hirokazu H; Kikukawa, Yoshiya Y; Koya, Junji J; Saito, Yuki Y; Tabata, Mariko M; Yoshifuji, Kota K; Mizuno, Kota K; Miyagi-Maeshima, Akiko A; Matsushita, Hiromichi H; Sugiyama, Masanaka M; Ogawa, Chitose C; Inamoto, Yoshihiro Y; Fukuda, Takahiro T; Sugano, Masato M; Yamauchi, Nobuhiko N; Minami, Yosuke Y; Hirata, Makoto M; Yoshida, Teruhiko T; Kohno, Takashi T; Kohsaka, Shinji S; Mano, Hiroyuki H; Shiraishi, Yuichi Y; Ogawa, Seishi S; Izutsu, Koji K; Kataoka, Keisuke K
Publication Date: 2022-08

Variant appearance in text: TP53: R280T
PubMed Link: 35579198
Variant Present in the following documents:
  • CAS-113-2763-s003.xlsx, sheet 10
View BVdb publication page



Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.

Nature Communications
Zhang, Yiqun Y; Chen, Fengju F; Chandrashekar, Darshan S DS; Varambally, Sooryanarayana S; Creighton, Chad J CJ
Publication Date: 2022-05-13

Variant appearance in text: p53: R280T
PubMed Link: 35562349
Variant Present in the following documents:
  • 41467_2022_30342_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine
Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y
Publication Date: 2022-07

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 35393784
Variant Present in the following documents:
  • CAM4-11-2767-s001.xlsx, sheet 1
View BVdb publication page



Analysis of the genomic landscapes of Barbadian and Nigerian women with triple negative breast cancer.

Cancer Causes & Control : Ccc
Hercules, Shawn M SM; Liu, Xiyu X; Bassey-Archibong, Blessing B I BBI; Skeete, Desiree H A DHA; Smith Connell, Suzanne S; Daramola, Adetola A; Banjo, Adekunbiola A AA; Ebughe, Godwin G; Agan, Thomas T; Ekanem, Ima-Obong IO; Udosen, Joe J; Obiorah, Christopher C; Ojule, Aaron C AC; Misauno, Michael A MA; Dauda, Ayuba M AM; Egbujo, Ejike C EC; Hercules, Jevon C JC; Ansari, Amna A; Brain, Ian I; MacColl, Christine C; Xu, Yili Y; Jin, Yuxin Y; Chang, Sharon S; Carpten, John D JD; Bédard, André A; Pond, Greg R GR; Blenman, Kim R M KRM; Manojlovic, Zarko Z; Daniel, Juliet M JM
Publication Date: 2022-06

Variant appearance in text: TP53: 839G>C; Arg280Thr; rs121912660
PubMed Link: 35384527
Variant Present in the following documents:
  • 10552_2022_1574_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Evaluation of the Clinical Utility of Genomic Profiling to Inform Selection of Clinical Trial Therapy in Salivary Gland Cancer.

Cancers
Rack, Samuel S; Feeney, Laura L; Hapuarachi, Brindley B; Adderley, Helen H; Woodhouse, Laura L; Betts, Guy G; Burghel, George J GJ; Harrington, Kevin J KJ; Metcalf, Robert R
Publication Date: 2022-02-23

Variant appearance in text: TP53: 839G>C; Arg280Thr
PubMed Link: 35267442
Variant Present in the following documents:
  • cancers-14-01133.pdf
View BVdb publication page



Real-world circulating tumor DNA analysis depicts resistance mechanism and clonal evolution in ALK inhibitor-treated lung adenocarcinoma patients.

Esmo Open
Hua, G G; Zhang, X X; Zhang, M M; Wang, Q Q; Chen, X X; Yu, R R; Bao, H H; Liu, J J; Wu, X X; Shao, Y Y; Liang, B B; Lu, K K
Publication Date: 2022-02

Variant appearance in text: TP53: R280T
PubMed Link: 35123209
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Real-world circulating tumor DNA analysis depicts resistance mechanism and clonal evolution in ALK inhibitor-treated lung adenocarcinoma patients.

Esmo Open
Hua, G G; Zhang, X X; Zhang, M M; Wang, Q Q; Chen, X X; Yu, R R; Bao, H H; Liu, J J; Wu, X X; Shao, Y Y; Liang, B B; Lu, K K
Publication Date: 2022-02-02

Variant appearance in text: TP53: R280T
PubMed Link: 35123209
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Somatic and Germline Genomic Alterations in Very Young Women with Breast Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Waks, Adrienne G AG; Kim, Dewey D; Jain, Esha E; Snow, Craig C; Kirkner, Gregory J GJ; Rosenberg, Shoshana M SM; Oh, Coyin C; Poorvu, Philip D PD; Ruddy, Kathryn J KJ; Tamimi, Rulla M RM; Peppercorn, Jeffrey J; Schapira, Lidia L; Borges, Virginia F VF; Come, Steven E SE; Brachtel, Elena F EF; Warner, Ellen E; Collins, Laura C LC; Partridge, Ann H AH; Wagle, Nikhil N
Publication Date: 2022-06-01

Variant appearance in text: rs121912660
PubMed Link: 35101884
Variant Present in the following documents:
  • ccr-21-2572_supplementary_table_s1_supps1.xlsx, sheet 2
View BVdb publication page



Investigation of PALB2 Mutation and Correlation With Immunotherapy Biomarker in Chinese Non-Small Cell Lung Cancer Patients.

Frontiers In Oncology
Zhang, Jiexia J; Tang, Shuangfeng S; Zhang, Chunning C; Li, Mingyao M; Zheng, Yating Y; Hu, Xue X; Huang, Mengli M; Cheng, Xiangyang X
Publication Date: 2021

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 35087742
Variant Present in the following documents:
  • Table_2.xlsx, sheet 1
View BVdb publication page



Therapeutic targeting of ARID1A and PI3K/AKT pathway alterations in cholangiocarcinoma.

Peerj
Tessiri, Supharada S; Techasen, Anchalee A; Kongpetch, Sarinya S; Namjan, Achira A; Loilome, Watcharin W; Chan-On, Waraporn W; Thanan, Raynoo R; Jusakul, Apinya A
Publication Date: 2022

Variant appearance in text: TP53: R280T
PubMed Link: 35070505
Variant Present in the following documents:
  • peerj-10-12750-s003.xlsx, sheet 1
View BVdb publication page



The dominant TP53 hotspot mutation in -mutant astrocytoma, R273C, has distinctive pathologic features and sex-specific prognostic implications.

Neuro-Oncology Advances
Marker, Daniel F DF; Agnihotri, Sameer S; Amankulor, Nduka N; Murdoch, Geoffrey H GH; Pearce, Thomas M TM
Publication Date: 2022

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 35047821
Variant Present in the following documents:
  • vdab182_suppl_supplementary_table_s1.xlsx, sheet 1
  • vdab182_suppl_supplementary_table_s1.xlsx, sheet 3
View BVdb publication page



A Quantitative Systems Approach to Define Novel Effects of Tumour p53 Mutations on Binding Oncoprotein MDM2.

International Journal Of Molecular Sciences
Fuentes, Manuel M; Srivastava, Sanjeeva S; Gronenborn, Angela M AM; LaBaer, Joshua J
Publication Date: 2021-12-21

Variant appearance in text: p53: Arg280Thr
PubMed Link: 35008477
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Quantitative Systems Approach to Define Novel Effects of Tumour p53 Mutations on Binding Oncoprotein MDM2.

International Journal Of Molecular Sciences
Fuentes, Manuel M; Srivastava, Sanjeeva S; Gronenborn, Angela M AM; LaBaer, Joshua J
Publication Date: 2021-12-21

Variant appearance in text: p53: Arg280Thr
PubMed Link: 35008477
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular Characterization, Via Next-Generation Sequencing, of Refractory or Resistant Invasive Breast Carcinoma.

Cureus
Pose Lapausa, Patricia P; Soria Comes, Teresa T; Calabria, Inés I; Maestu Maiques, Inmaculada I
Publication Date: 2021-11

Variant appearance in text: TP53: 839G>C; Arg280Thr
PubMed Link: 34934548
Variant Present in the following documents:
  • Main text
  • cureus-0013-00000019528.pdf
View BVdb publication page



ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide.

Oncotarget
El Touny, Lara H LH; Hose, Curtis C; Connelly, John J; Harris, Erik E; Monks, Anne A; Dull, Angie B AB; Wilsker, Deborah F DF; Hollingshead, Melinda G MG; Gottholm-Ahalt, Michelle M; Alcoser, Sergio Y SY; Mullendore, Michael E ME; Parchment, Ralph E RE; Doroshow, James H JH; Teicher, Beverly A BA; Rapisarda, Annamaria A
Publication Date: 2021-10-12

Variant appearance in text: p53: R280T
PubMed Link: 34676045
Variant Present in the following documents:
  • oncotarget-12-2114-s001.pdf
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: TP53: R280T
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Molecular profiling of advanced malignancies guides first-line N-of-1 treatments in the I-PREDICT treatment-naïve study.

Genome Medicine
Sicklick, Jason K JK; Kato, Shumei S; Okamura, Ryosuke R; Patel, Hitendra H; Nikanjam, Mina M; Fanta, Paul T PT; Hahn, Michael E ME; De, Pradip P; Williams, Casey C; Guido, Jessica J; Solomon, Benjamin M BM; McKay, Rana R RR; Krie, Amy A; Boles, Sarah G SG; Ross, Jeffrey S JS; Lee, J Jack JJ; Leyland-Jones, Brian B; Lippman, Scott M SM; Kurzrock, Razelle R
Publication Date: 2021-10-04

Variant appearance in text: TP53: R280T
PubMed Link: 34607609
Variant Present in the following documents:
  • 13073_2021_969_MOESM1_ESM.xlsx, sheet 2
View BVdb publication page



FDG positron emission tomography imaging and ctDNA detection as an early dynamic biomarker of everolimus efficacy in advanced luminal breast cancer.

Npj Breast Cancer
Gombos, Andrea A; Venet, David D; Ameye, Lieveke L; Vuylsteke, Peter P; Neven, Patrick P; Richard, Vincent V; Duhoux, Francois P FP; Laes, Jean-Francois JF; Rothe, Françoise F; Sotiriou, Christos C; Paesmans, Marianne M; Awada, Ahmad A; Guiot, Thomas T; Flamen, Patrick P; Piccart-Gebhart, Martine M; Ignatiadis, Michail M; Gebhart, Géraldine G
Publication Date: 2021-09-21

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 34548493
Variant Present in the following documents:
  • 41523_2021_331_MOESM1_ESM.pdf
View BVdb publication page



Genetic profiles of Barrett's esophagus and esophageal adenocarcinoma in Japanese patients.

Scientific Reports
Tokunaga, Mamoru M; Okimoto, Kenichiro K; Akizue, Naoki N; Ishikawa, Kentaro K; Hirotsu, Yosuke Y; Amemiya, Kenji K; Ota, Masayuki M; Matsusaka, Keisuke K; Nishimura, Motoi M; Matsushita, Kazuyuki K; Ishikawa, Tsubasa T; Nagashima, Ariki A; Shiratori, Wataru W; Kaneko, Tatsuya T; Oura, Hirotaka H; Kanayama, Kengo K; Ohta, Yuki Y; Taida, Takashi T; Saito, Keiko K; Matsumura, Tomoaki T; Chiba, Tetsuhiro T; Mochizuki, Hitoshi H; Arai, Makoto M; Kato, Jun J; Ikeda, Jun-Ichiro JI; Omata, Masao M; Kato, Naoya N
Publication Date: 2021-09-03

Variant appearance in text: TP53: R280T
PubMed Link: 34480065
Variant Present in the following documents:
  • Main text
  • 41598_2021_Article_97249.pdf
View BVdb publication page



TP53 isoform junction reads based analysis in malignant and normal contexts.

Scientific Reports
Vural, Suleyman S; Chang, Lun-Ching LC; Yee, Laura M LM; Sonkin, Dmitriy D
Publication Date: 2021-08-26

Variant appearance in text: TP53: R280T
PubMed Link: 34446762
Variant Present in the following documents:
  • 41598_2021_96700_MOESM1_ESM.xlsx, sheet 2
View BVdb publication page



Loss of Smad4 promotes aggressive lung cancer metastasis by de-repression of PAK3 via miRNA regulation.

Nature Communications
Tan, Xiaohong X; Tong, Lu L; Li, Lin L; Xu, Jinjin J; Xie, Shaofang S; Ji, Lei L; Fu, Junjiang J; Liu, Qingwu Q; Shen, Shihui S; Liu, Yun Y; Xiao, Yanhui Y; Gao, Feiran F; Moses, Robb E RE; Bardeesy, Nabeel N; Wang, Yanxiao Y; Zhang, Jishuai J; Tang, Longying L; Li, Lei L; Wong, Kwok-Kin KK; Song, Dianwen D; Yang, Xiao X; Liu, Jian J; Li, Xiaotao X
Publication Date: 2021-08-11

Variant appearance in text: TP53: R280T
PubMed Link: 34381046
Variant Present in the following documents:
  • 41467_2021_24898_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Metastatic pediatric sclerosing epithelioid fibrosarcoma.

Cold Spring Harbor Molecular Case Studies
Woods, Andrew D AD; Purohit, Reshma R; Mitchell, Laura Crocker LC; Collier, John R JR; Collier, Katherine A KA; Lathara, Melvin M; Learned, Katrina K; Vaske, Olena O; Geiger, Heather H; Wrzeszczynski, Kazimierz O KO; Jobanputra, Vaidehi V; Srinivasa, Ganapati G; Rudzinski, Erin R ER; Whelan, Kimberly K; Beierle, Elizabeth E; Spunt, Sheri L SL; Keller, Charles C; Wadhwa, Aman A
Publication Date: 2021-10

Variant appearance in text: p53: R280T
PubMed Link: 34362827
Variant Present in the following documents:
  • Main text
View BVdb publication page



A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports
Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM
Publication Date: 2021-07-12

Variant appearance in text: TP53: 839G>C; R280T
PubMed Link: 34253785
Variant Present in the following documents:
  • 41598_2021_93715_MOESM2_ESM.xlsx, sheet 10
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 5
View BVdb publication page