TP53 c.838_839delinsGC ;(p.R280A)

Variant ID: 17-7577099-CT-GC

NM_000546.5(TP53):c.838_839delinsGC;(p.R280A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: TP53: R280A
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Mutagenicity of acrylamide and glycidamide in human TP53 knock-in (Hupki) mouse embryo fibroblasts.

Archives Of Toxicology
Hölzl-Armstrong, Lisa L; Kucab, Jill E JE; Moody, Sarah S; Zwart, Edwin P EP; Loutkotová, Lucie L; Duffy, Veronica V; Luijten, Mirjam M; Gamboa da Costa, Gonçalo G; Stratton, Michael R MR; Phillips, David H DH; Arlt, Volker M VM
Publication Date: 2020-12

Variant appearance in text: TP53: R280a
PubMed Link: 32886187
Variant Present in the following documents:
  • 204_2020_Article_2878.pdf
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: TP53: R280A
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Chen, Shuo S; Wu, Jiale J; Zhong, Shan S; Li, Yuntong Y; Zhang, Ping P; Ma, Jingyi J; Ren, Jingshan J; Tan, Yun Y; Wang, Yunhao Y; Au, Kin Fai KF; Siebold, Christian C; Bond, Gareth L GL; Chen, Zhu Z; Lu, Min M; Jones, E Yvonne EY; Lu, Xin X
Publication Date: 2019-08-27

Variant appearance in text: p53: R280A
PubMed Link: 31395738
Variant Present in the following documents:
  • pnas.201909393.pdf
View BVdb publication page



Delivery of a monomeric p53 subdomain with mitochondrial targeting signals from pro-apoptotic Bak or Bax.

Pharmaceutical Research
Matissek, Karina J KJ; Okal, Abood A; Mossalam, Mohanad M; Lim, Carol S CS
Publication Date: 2014-09

Variant appearance in text: p53: R280A
PubMed Link: 24633417
Variant Present in the following documents:
  • Main text
View BVdb publication page



Oligomerization of BAK by p53 utilizes conserved residues of the p53 DNA binding domain.

The Journal Of Biological Chemistry
Pietsch, E Christine EC; Perchiniak, Erin E; Canutescu, Adrian A AA; Wang, Guoli G; Dunbrack, Roland L RL; Murphy, Maureen E ME
Publication Date: 2008-07-25

Variant appearance in text: p53: R280A
PubMed Link: 18524770
Variant Present in the following documents:
  • Main text
View BVdb publication page