TP53 c.808_809delinsGC ;(p.F270A)

Variant ID: 17-7577129-AA-GC

NM_000546.5(TP53):c.808_809delinsGC;(p.F270A)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


TP53 variants in p53 signatures and the clonality of STICs in RRSO samples.

Journal Of Gynecologic Oncology
Akahane, Tomoko T; Masuda, Kenta K; Hirasawa, Akira A; Kobayashi, Yusuke Y; Ueki, Arisa A; Kawaida, Miho M; Misu, Kumiko K; Nakamura, Kohei K; Nagai, Shimpei S; Chiyoda, Tatsuyuki T; Yamagami, Wataru W; Hayashi, Shigenori S; Kataoka, Fumio F; Banno, Kouji K; Sugano, Kokichi K; Okita, Hajime H; Kosaki, Kenjiro K; Nishihara, Hiroshi H; Aoki, Daisuke D
Publication Date: 2022-07

Variant appearance in text: TP53: F270A
PubMed Link: 35557033
Variant Present in the following documents:
  • jgo-33-e50-s005.xls, sheet 1
  • jgo-33-e50-s002.xls, sheet 1
View BVdb publication page



Controlled access of p53 to the nucleus regulates its proteasomal degradation by MDM2.

Molecular Pharmaceutics
Davis, James R JR; Mossalam, Mohanad M; Lim, Carol S CS
Publication Date: 2013-04-01

Variant appearance in text: p53: F270A
PubMed Link: 23398638
Variant Present in the following documents:
  • Main text
View BVdb publication page



Inhibition of p53 by adenovirus type 12 E1B-55K deregulates cell cycle control and sensitizes tumor cells to genotoxic agents.

Journal Of Virology
Li, Qiang Q; Zhao, Lisa Y LY; Zheng, Zhi Z; Yang, Heng H; Santiago, Aleixo A; Liao, Daiqing D
Publication Date: 2011-08

Variant appearance in text: p53: F270A
PubMed Link: 21680522
Variant Present in the following documents:
  • Main text
View BVdb publication page



A novel p53 phosphorylation site within the MDM2 ubiquitination signal: II. a model in which phosphorylation at SER269 induces a mutant conformation to p53.

The Journal Of Biological Chemistry
Fraser, Jennifer A JA; Madhumalar, Arumugam A; Blackburn, Elizabeth E; Bramham, Janice J; Walkinshaw, Malcolm D MD; Verma, Chandra C; Hupp, Ted R TR
Publication Date: 2010-11-26

Variant appearance in text: p53: F270A
PubMed Link: 20847049
Variant Present in the following documents:
  • Main text
View BVdb publication page



Destabilizing missense mutations in the tumour suppressor protein p53 enhance its ubiquitination in vitro and in vivo.

The Biochemical Journal
Shimizu, Harumi H; Saliba, David D; Wallace, Maura M; Finlan, Lee L; Langridge-Smith, Patrick R R PR; Hupp, Ted R TR
Publication Date: 2006-07-15

Variant appearance in text: p53: F270A
PubMed Link: 16579792
Variant Present in the following documents:
  • Main text
View BVdb publication page