Publications:

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Targeting the p53 signaling pathway in cancers: Molecular mechanisms and clinical studies.

Medcomm

Shen, Jinze J; Wang, Qurui Q; Mao, Yunan Y; Gao, Wei W; Duan, Shiwei S

Publication Date: 2023-06

Variant appearance in text: p53: R249S

PubMed Link: 37256211

Variant Present in the following documents:

• Main text
• MCO2-4-e288.pdf

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Genetic mutations in HER2-positive breast cancer: possible association with response to trastuzumab therapy.

Human Genomics

Zakaria, Nermine H NH; Hashad, Doaa D; Saied, Marwa H MH; Hegazy, Neamat N; Elkayal, Alyaa A; Tayae, Eman E

Publication Date: 2023-05-18

Variant appearance in text: TP53: Arg249Ser

PubMed Link: 37202799

Variant Present in the following documents:

• Main text
• 40246_2023_Article_493.pdf

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Surveillance of cfDNA Hot Spot Mutations in NSCLC Patients during Disease Progression.

International Journal Of Molecular Sciences

Sestokaite, Agne A; Gedvilaite, Vaida V; Cicenas, Saulius S; Sabaliauskaite, Rasa R; Jarmalaite, Sonata S

Publication Date: 2023-04-09

Variant appearance in text: TP53: R249S

PubMed Link: 37108122

Variant Present in the following documents:

• Main text
• ijms-24-06958.pdf

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Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis.

Cell Death Discovery

Romanovsky, Eva E; Kluck, Klaus K; Ourailidis, Iordanis I; Menzel, Michael M; Beck, Susanne S; Ball, Markus M; Kazdal, Daniel D; Christopoulos, Petros P; Schirmacher, Peter P; Stiewe, Thorsten T; Stenzinger, Albrecht A; Budczies, Jan J

Publication Date: 2023-04-14

Variant appearance in text: TP53: R249S

PubMed Link: 37059713

Variant Present in the following documents:

• Main text
• 41420_2023_Article_1413.pdf

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Concomitant TP53 mutation in early-stage resected EGFR-mutated non-small cell lung cancer: a narrative approach in a genetically admixed Brazilian cohort.

Brazilian Journal Of Medical And Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas

Machado-Rugolo, J J; Baldavira, C M CM; Prieto, T G TG; Olivieri, E H R EHR; Fabro, A T AT; Rainho, C A CA; Castelli, E C EC; Ribolla, P E M PEM; Ab'Saber, A M AM; Takagaki, T T; Nagai, M A MA; Capelozzi, V L VL

Publication Date: 2023

Variant appearance in text: TP53: 747G>C; rs28934571

PubMed Link: 37042869

Variant Present in the following documents:

• Main text
• 1414-431X-bjmbr-56-e12488.pdf

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Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications

Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA

Publication Date: 2023-04-03

Variant appearance in text: TP53: R249S

PubMed Link: 37012232

Variant Present in the following documents:

• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 3
• 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2

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Precise pancreatic cancer therapy through targeted degradation of mutant p53 protein by cerium oxide nanoparticles.

Journal Of Nanobiotechnology

Zhang, Hao H; Zhang, Wang W; Hu, Bochuan B; Qin, Xiaohua X; Yi, Tianxiang T; Ye, Yayi Y; Huang, Xiaowan X; Song, Yang Y; Yang, Zhenyu Z; Qian, Jieying J; Zhang, Yunjiao Y

Publication Date: 2023-04-01

Variant appearance in text: p53: R249S

PubMed Link: 37005668

Variant Present in the following documents:

• Main text
• 12951_2023_Article_1867.pdf

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Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer

Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J

Publication Date: 2023-03-31

Variant appearance in text: TP53: Arg249Ser

PubMed Link: 37004022

Variant Present in the following documents:

• 12885_2023_10674_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Amino acid metabolic reprogramming in tumor metastatic colonization.

Frontiers In Oncology

Wang, Zihao Z; Wu, Xingyun X; Chen, Hai-Ning HN; Wang, Kui K

Publication Date: 2023

Variant appearance in text: TP53: R249S

PubMed Link: 36998464

Variant Present in the following documents:

• Main text
• fonc-13-1123192.pdf

View BVdb publication page

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Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation.

Nature Communications

Xu, An A; Liu, Mo M; Huang, Mo-Fan MF; Zhang, Yang Y; Hu, Ruifeng R; Gingold, Julian A JA; Liu, Ying Y; Zhu, Dandan D; Chien, Chian-Shiu CS; Wang, Wei-Chen WC; Liao, Zian Z; Yuan, Fei F; Hsu, Chih-Wei CW; Tu, Jian J; Yu, Yao Y; Rosen, Taylor T; Xiong, Feng F; Jia, Peilin P; Yang, Yi-Ping YP; Bazer, Danielle A DA; Chen, Ya-Wen YW; Li, Wenbo W; Huff, Chad D CD; Zhu, Jay-Jiguang JJ; Aguilo, Francesca F; Chiou, Shih-Hwa SH; Boles, Nathan C NC; Lai, Chien-Chen CC; Hung, Mien-Chie MC; Zhao, Zhongming Z; Van Nostrand, Eric L EL; Zhao, Ruiying R; Lee, Dung-Fang DF

Publication Date: 2023-03-27

Variant appearance in text: p53: R249S

PubMed Link: 36973285

Variant Present in the following documents:

• Main text
• 41467_2023_Article_37398.pdf

View BVdb publication page

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Characteristics and prognosis of rrDLBCL with TP53 mutations and a high-risk subgroup represented by the co-mutations of DDX3X-TP53.

Cancer Medicine

Gao, Fan F; Hu, Kai K; Zheng, Peihao P; Shi, Hui H; Ke, Xiaoyan X

Publication Date: 2023-03-27

Variant appearance in text: TP53: R249S; rs28934571

PubMed Link: 36971051

Variant Present in the following documents:

• CAM4-12-10267-s002.xlsx, sheet 1

View BVdb publication page

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Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types.

Scientific Reports

Sasaki, Keiju K; Takahashi, Shin S; Ouchi, Kota K; Otsuki, Yasufumi Y; Wakayama, Shonosuke S; Ishioka, Chikashi C

Publication Date: 2023-03-24

Variant appearance in text: p53: R249S

PubMed Link: 36964217

Variant Present in the following documents:

• 41598_2023_Article_32092.pdf
• 41598_2023_32092_MOESM1_ESM.xlsx, sheet 4

View BVdb publication page

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Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity.

Nature Genetics

Mangiante, Lise L; Alcala, Nicolas N; Sexton-Oates, Alexandra A; Di Genova, Alex A; Gonzalez-Perez, Abel A; Khandekar, Azhar A; Bergstrom, Erik N EN; Kim, Jaehee J; Liu, Xiran X; Blazquez-Encinas, Ricardo R; Giacobi, Colin C; Le Stang, Nolwenn N; Boyault, Sandrine S; Cuenin, Cyrille C; Tabone-Eglinger, Severine S; Damiola, Francesca F; Voegele, Catherine C; Ardin, Maude M; Michallet, Marie-Cecile MC; Soudade, Lorraine L; Delhomme, Tiffany M TM; Poret, Arnaud A; Brevet, Marie M; Copin, Marie-Christine MC; Giusiano-Courcambeck, Sophie S; Damotte, Diane D; Girard, Cecile C; Hofman, Veronique V; Hofman, Paul P; Mouroux, Jérôme J; Cohen, Charlotte C; Lacomme, Stephanie S; Mazieres, Julien J; de Montpreville, Vincent Thomas VT; Perrin, Corinne C; Planchard, Gaetane G; Rousseau, Nathalie N; Rouquette, Isabelle I; Sagan, Christine C; Scherpereel, Arnaud A; Thivolet, Francoise F; Vignaud, Jean-Michel JM; Jean, Didier D; Ilg, Anabelle Gilg Soit AGS; Olaso, Robert R; Meyer, Vincent V; Boland-Auge, Anne A; Deleuze, Jean-Francois JF; Altmuller, Janine J; Nuernberg, Peter P; Ibáñez-Costa, Alejandro A; Castaño, Justo P JP; Lantuejoul, Sylvie S; Ghantous, Akram A; Maussion, Charles C; Courtiol, Pierre P; Hernandez-Vargas, Hector H; Caux, Christophe C; Girard, Nicolas N; Lopez-Bigas, Nuria N; Alexandrov, Ludmil B LB; Galateau-Salle, Françoise F; Foll, Matthieu M; Fernandez-Cuesta, Lynnette L

Publication Date: 2023-03-16

Variant appearance in text: rs28934571

PubMed Link: 36928603

Variant Present in the following documents:

• 41588_2023_1321_MOESM4_ESM.xlsx, sheet 44

View BVdb publication page

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Role of p53 in breast cancer progression: An insight into p53 targeted therapy.

Theranostics

Marvalim, Charlie C; Datta, Arpita A; Lee, Soo Chin SC

Publication Date: 2023

Variant appearance in text: p53: R249S

PubMed Link: 36923534

Variant Present in the following documents:

• Main text
• thnov13p1421.pdf

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p53 mutation and deletion contribute to tumor immune evasion.

Frontiers In Genetics

Liu, Siyang S; Liu, Tianyao T; Jiang, Jiaxuan J; Guo, Hongqian H; Yang, Rong R

Publication Date: 2023

Variant appearance in text: p53: R249S

PubMed Link: 36891151

Variant Present in the following documents:

• Main text
• fgene-14-1088455.pdf

View BVdb publication page

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OPUS-Mut: Studying the Effect of Protein Mutation through Side-Chain Modeling.

Journal Of Chemical Theory And Computation

Xu, Gang G; Wang, Qinghua Q; Ma, Jianpeng J

Publication Date: 2023-02-22

Variant appearance in text: p53: R249S

PubMed Link: 36813264

Variant Present in the following documents:

• Main text
• ct2c00847.pdf

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Clinical impact of TP53 disruption in chronic lymphocytic leukemia patients treated with ibrutinib: a campus CLL study.

Leukemia

Bomben, Riccardo R; Rossi, Francesca Maria FM; Vit, Filippo F; Bittolo, Tamara T; Zucchetto, Antonella A; Papotti, Robel R; Tissino, Erika E; Pozzo, Federico F; Degan, Massimo M; Polesel, Jerry J; Bulian, Pietro P; Marasca, Roberto R; Reda, Gianluigi G; Laurenti, Luca L; Olivieri, Jacopo J; Chiarenza, Annalisa A; Laureana, Roberta R; Postorino, Massimiliano M; Del Principe, Maria Ilaria MI; Cuneo, Antonio A; Gentile, Massimo M; Morabito, Fortunato F; Fronza, Gilberto G; Tafuri, Agostino A; Zaja, Francesco F; Foà, Robin R; Di Raimondo, Francesco F; Del Poeta, Giovanni G; Gattei, Valter V

Publication Date: 2023-02-18

Variant appearance in text: TP53: 747G>C; R249S

PubMed Link: 36807650

Variant Present in the following documents:

• 41375_2023_1845_MOESM1_ESM.pdf

View BVdb publication page

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Dynamics of age- versus therapy-related clonal hematopoiesis in long-term survivors of pediatric cancer.

Cancer Discovery

Hagiwara, Kohei K; Natarajan, Sivaraman S; Wang, Zhaoming Z; Zubair, Haseeb H; Mulder, Heather L HL; Dong, Li L; Plyler, Emily M EM; Thimmaiah, Padma P; Ma, Xiaotu X; Ness, Kirsten K KK; Li, Zhenghong Z; Mulrooney, Daniel A DA; Wilson, Carmen L CL; Yasui, Yutaka Y; Hudson, Melissa M MM; Easton, John J; Robison, Leslie L LL; Zhang, Jinghui J

Publication Date: 2023-02-08

Variant appearance in text: TP53: R249S

PubMed Link: 36751942

Variant Present in the following documents:

• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 4
• cd-22-0956_tables_s2_s7_s8_s9_suppst1.xlsx, sheet 1

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FGF19 promotes cell autophagy and cisplatin chemoresistance by activating MAPK signaling in ovarian cancer.

Peerj

Zhu, Wei W; Huang, Meiyuan M; Thakur, Abhimanyu A; Yan, Yuanliang Y; Wu, Xiaoying X

Publication Date: 2023

Variant appearance in text: TP53: 747G>C; R249S; rs28934571

PubMed Link: 36751636

Variant Present in the following documents:

• peerj-11-14827-s010.xlsx, sheet 1

View BVdb publication page

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Genetic testing and prognosis of sarcomatoid hepatocellular carcinoma patients.

Frontiers In Oncology

Jia, Bin B; Xia, Peiyi P; Dong, Junqiang J; Feng, Wenhao W; Wang, Wenjia W; Liu, Enjie E; Jiang, Guozhong G; Qin, Yanru Y

Publication Date: 2022

Variant appearance in text: TP53: R249S

PubMed Link: 36741696

Variant Present in the following documents:

• Main text
• fonc-12-1086908.pdf

View BVdb publication page

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NF-YAl drives EMT in Claudinlow tumours.

Cell Death & Disease

Londero, Michela M; Gallo, Alberto A; Cattaneo, Camilla C; Ghilardi, Anna A; Ronzio, Mirko M; Del Giacco, Luca L; Mantovani, Roberto R; Dolfini, Diletta D

Publication Date: 2023-01-28

Variant appearance in text: p53: R249S

PubMed Link: 36707502

Variant Present in the following documents:

• Main text
• 41419_2023_Article_5591.pdf

View BVdb publication page

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Whole-genome characterization of large-cell lung carcinoma: A comparative analysis based on the histological classification.

Frontiers In Genetics

Wu, Xiaowei X; Yin, Jin J; Deng, Yu Y; Zu, Yukun Y

Publication Date: 2022

Variant appearance in text: TP53: R249S

PubMed Link: 36685819

Variant Present in the following documents:

• Main text
• fgene-13-1070048.pdf

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C-Terminal p53 Palindromic Tetrapeptide Restores Full Apoptotic Function to Mutant p53 Cancer Cells In Vitro and In Vivo.

Biomedicines

Fine, Robert L RL; Mao, Yuehua Y; Dinnen, Richard R; Rosal, Ramon V RV; Raffo, Anthony A; Hochfeld, Uri U; Senatus, Patrick P; Bruce, Jeffrey N JN; Nichols, Gwen G; Wang, Hsin H; Li, Yongliang Y; Brandt-Rauf, Paul W PW

Publication Date: 2023-01-05

Variant appearance in text: p53: R249S

PubMed Link: 36672645

Variant Present in the following documents:

• Main text
• biomedicines-11-00137.pdf

View BVdb publication page

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The High Expression of p53 Is Predictive of Poor Survival Rather TP53 Mutation in Esophageal Squamous Cell Carcinoma.

Journal Of Oncology

Jin, Yan Y; Zhao, Xueke X; Song, Xin X; Wang, Ran R; Fan, Zongmin Z; Wang, Panpan P; Yang, Miaomiao M; Zhou, Fuyou F; Bao, Qide Q; Wang, Lidong L

Publication Date: 2023

Variant appearance in text: TP53: R249S

PubMed Link: 36660245

Variant Present in the following documents:

• JO2023-3801526.pdf

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Characterization of driver mutations in Chinese non-small cell lung cancer patients using a novel targeted sequencing panel.

Journal Of Thoracic Disease

Zhao, Jing J; Wu, Yang Y; Chen, Min-Jiang MJ; Xu, Yan Y; Zhong, Wei W; Wang, Meng-Zhao MZ

Publication Date: 2022-12

Variant appearance in text: TP53: R249S

PubMed Link: 36647494

Variant Present in the following documents:

• Main text
• jtd-14-12-4669.pdf

View BVdb publication page

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Health inequalities in the management of chronic hepatitis B virus infection in patients from sub-Saharan Africa in high-income countries.

Jhep Reports : Innovation In Hepatology

Mitchell, Tim T; Nayagam, Jeremy S JS; Dusheiko, Geoffrey G; Agarwal, Kosh K

Publication Date: 2023-02

Variant appearance in text: TP53: R249S

PubMed Link: 36636709

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Hepatocellular Carcinoma: Current Therapeutic Algorithm for Localized and Advanced Disease.

Journal Of Oncology

Jose, Anju A; Bavetta, Maria Grazia MG; Martinelli, Erika E; Bronte, Fabrizio F; Giunta, Emilio Francesco EF; Manu, Kanjoormana Aryan KA

Publication Date: 2022

Variant appearance in text: TP53: R249S

PubMed Link: 36624801

Variant Present in the following documents:

• JO2022-3817724.pdf

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Non-CpG sites preference in G:C > A:T transition of TP53 in gastric cancer of Eastern Europe (Poland, Romania and Hungary) compared to East Asian countries (China and Japan).

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society

Natsume, Hiroko H; Szczepaniak, Kinga K; Yamada, Hidetaka H; Iwashita, Yuji Y; Gędek, Marta M; Šuto, Jelena J; Ishino, Keiko K; Kasajima, Rika R; Matsuda, Tomonari T; Manirakiza, Felix F; Nzitakera, Augustin A; Wu, Yijia Y; Xiao, Nong N; He, Qiong Q; Guo, Wenwen W; Cai, Zhenming Z; Ohta, Tsutomu T; Szekely, Tıberiu T; Kadar, Zoltan Z; Sekiyama, Akiko A; Oshima, Takashi T; Yoshikawa, Takaki T; Tsuburaya, Akira A; Kurono, Nobuhito N; Wang, Yaping Y; Miyagi, Yohei Y; Gurzu, Simona S; Sugimura, Haruhiko H

Publication Date: 2023-01-04

Variant appearance in text: TP53: Arg249Ser

PubMed Link: 36600315

Variant Present in the following documents:

• Main text
• 41021_2022_Article_257.pdf

View BVdb publication page

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BAG2 drives chemoresistance of breast cancer by exacerbating mutant p53 aggregate.

Theranostics

Huang, Xinjian X; Shi, Dongni D; Zou, Xuxiazi X; Wu, Xuxia X; Huang, Shumei S; Kong, Lingzhi L; Yang, Muwen M; Xiao, Yunyun Y; Chen, Boyu B; Chen, Xiangfu X; Ouyang, Ying Y; Song, Libing L; Jian, Yunting Y; Lin, Chuyong C

Publication Date: 2023

Variant appearance in text: p53: R249S

PubMed Link: 36593950

Variant Present in the following documents:

• thnov13p0339s1.pdf
• thnov13p0339.pdf

View BVdb publication page

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Transition of amyloid/mutant p53 from tumor suppressor to an oncogene and therapeutic approaches to ameliorate metastasis and cancer stemness.

Cancer Cell International

Sengupta, Shinjinee S; Ghufran, Shaikh Maryam SM; Khan, Aqsa A; Biswas, Subhrajit S; Roychoudhury, Susanta S

Publication Date: 2022-12-26

Variant appearance in text: p53: R249S

PubMed Link: 36567312

Variant Present in the following documents:

• Main text
• 12935_2022_Article_2831.pdf

View BVdb publication page

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs28934571

PubMed Link: 36561320

Variant Present in the following documents:

• Table3.xlsx, sheet 1
• Table2.xlsx, sheet 7

View BVdb publication page

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Unraveling the Structural Changes in the DNA-Binding Region of Tumor Protein p53 (TP53) upon Hotspot Mutation p53 Arg248 by Comparative Computational Approach.

International Journal Of Molecular Sciences

Balasundaram, Ambritha A; Doss, C George Priya CGP

Publication Date: 2022-12-07

Variant appearance in text: p53: R249S

PubMed Link: 36555140

Variant Present in the following documents:

• Main text
• ijms-23-15499.pdf

View BVdb publication page

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Clinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy.

British Journal Of Cancer

Cifuentes, Guadalupe A GA; Santiago, Adrián A; Méndez Blanco, Lucía L; Fueyo, María M; López Martínez, Esther E; Soria, Raquel R; Martín López, Irene I; Cucarella Beltrán, Pepa P; Pardo-Coto, Pablo P; Rodriguez-Rubi, David D; Urquilla, Karla K; Durán, Noelia S NS; Álvarez, Rebeca R; Lago, Claudia G CG; Otero, Andrea A; Diñeiro, Marta M; Capín, Raquel R; Cadiñanos, Juan J; Cabanillas, Rubén R

Publication Date: 2022-12-22

Variant appearance in text: TP53: Arg249Ser

PubMed Link: 36550207

Variant Present in the following documents:

• 41416_2022_Article_2102.pdf

View BVdb publication page

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