TP53 c.668C>T ;(p.P223L)

Variant ID: 17-7578181-G-A

NM_000546.5(TP53):c.668C>T;(p.P223L)

This variant was identified in 102 publications

View GRCh38 version.




Publications:


Dexamethasone Selectively Inhibits Detachment of Metastatic Thyroid Cancer Cells during Random Positioning.

Cancers
Melnik, Daniela D; Cortés-Sánchez, José Luis JL; Sandt, Viviann V; Kahlert, Stefan S; Kopp, Sascha S; Grimm, Daniela D; Krüger, Marcus M
Publication Date: 2023-03-07

Variant appearance in text: TP53: P223L
PubMed Link: 36980530
Variant Present in the following documents:
  • cancers-15-01641.pdf
View BVdb publication page



Role of p53 in breast cancer progression: An insight into p53 targeted therapy.

Theranostics
Marvalim, Charlie C; Datta, Arpita A; Lee, Soo Chin SC
Publication Date: 2023

Variant appearance in text: p53: P223L
PubMed Link: 36923534
Variant Present in the following documents:
  • Main text
  • thnov13p1421.pdf
View BVdb publication page



Occurrence of variants of unknown clinical significance in genetic testing for hereditary breast and ovarian cancer syndrome and Lynch syndrome: a literature review and analytical observational retrospective cohort study.

Bmc Medical Genomics
Adam, Felicia F; Fluri, Muriel M; Scherz, Amina A; Rabaglio, Manuela M
Publication Date: 2023-01-16

Variant appearance in text: TP53: 668C>T
PubMed Link: 36647026
Variant Present in the following documents:
  • 12920_2023_1437_MOESM3_ESM.xlsx, sheet 1
  • 12920_2023_1437_MOESM2_ESM.xlsx, sheet 1
  • 12920_2023_1437_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: TP53: P223L
PubMed Link: 36561320
Variant Present in the following documents:
  • Table3.xlsx, sheet 1
  • Table2.xlsx, sheet 7
View BVdb publication page



Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics
Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q
Publication Date: 2022-11-04

Variant appearance in text: TP53: 668C>T; P223L
PubMed Link: 36333792
Variant Present in the following documents:
  • 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



Heterogeneity of the cancer cell line metabolic landscape.

Molecular Systems Biology
Shorthouse, David D; Bradley, Jenna J; Critchlow, Susan E SE; Bendtsen, Claus C; Hall, Benjamin A BA
Publication Date: 2022-11

Variant appearance in text: TP53: 668C>T
PubMed Link: 36321551
Variant Present in the following documents:
  • MSB-18-e11006-s010.xlsx, sheet 1
View BVdb publication page



Anticancer Therapeutic Strategies Targeting p53 Aggregation.

International Journal Of Molecular Sciences
Ferretti, Giulia D S GDS; Quarti, Julia J; Dos Santos, Gileno G; Rangel, Luciana P LP; Silva, Jerson L JL
Publication Date: 2022-09-20

Variant appearance in text: p53: P223L
PubMed Link: 36232329
Variant Present in the following documents:
  • Main text
  • ijms-23-11023.pdf
View BVdb publication page



CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience
Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X
Publication Date: 2022-09-16

Variant appearance in text: p53: 668C>T
PubMed Link: 36117989
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
  • mmc5.xlsx, sheet 1
View BVdb publication page



Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status.

Cancers
Mejía-Hernández, Javier Octavio JO; Raghu, Dinesh D; Caramia, Franco F; Clemons, Nicholas N; Fujihara, Kenji K; Riseborough, Thomas T; Teunisse, Amina A; Jochemsen, Aart G AG; Abrahmsén, Lars L; Blandino, Giovanni G; Russo, Andrea A; Gamell, Cristina C; Fox, Stephen B SB; Mitchell, Catherine C; Takano, Elena A EA; Byrne, David D; Miranda, Panimaya Jeffreena PJ; Saleh, Reem R; Thorne, Heather H; Sandhu, Shahneen S; Williams, Scott G SG; Keam, Simon P SP; Haupt, Ygal Y; Haupt, Sue S
Publication Date: 2022-08-16

Variant appearance in text: p53: p223L
PubMed Link: 36010941
Variant Present in the following documents:
  • Main text
  • cancers-14-03947.pdf
View BVdb publication page



Landscape of somatic alterations in large-scale solid tumors from an Asian population.

Nature Communications
Wu, Liqun L; Yao, Herui H; Chen, Hui H; Wang, Aodi A; Guo, Kun K; Gou, Wenli W; Yu, Yanfei Y; Li, Xiang X; Yao, Ming M; Yuan, Shaohua S; Pang, Fei F; Hu, Jinwei J; Chen, Lijuan L; Liu, Wenjin W; Yao, Jicheng J; Zhang, Shuirong S; Dong, Xiaowei X; Wang, Weifeng W; Hu, Jing J; Ling, Qi Q; Ding, Songming S; Wei, Yan Y; Li, Qiang Q; Cao, Weichun W; Wang, Shuang S; Di, Yang Y; Feng, Feiling F; Zhao, Gang G; Zhang, Jian J; Huang, Ling L; Xu, Jia J; Yan, Wangjun W; Tong, Zhongsheng Z; Jiang, Da D; Ji, Tao T; Li, Qiao Q; Xu, Ling L; He, Huiying H; Shang, Liang L; Liu, Jin J; Wang, Kefeng K; Wu, Duoguang D; Shen, Jingnan J; Liu, Ye Y; Zhang, Ting T; Liang, Chaojie C; Wang, Yusheng Y; Shang, Yanhong Y; Guo, Jianji J; Liang, Guanbiao G; Xu, Shifeng S; Liu, Junfeng J; Wang, Kai K; Wang, Minghui M
Publication Date: 2022-07-23

Variant appearance in text: TP53: P223L
PubMed Link: 35871175
Variant Present in the following documents:
  • 41467_2022_31780_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: TP53: 668C>T; A223V
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology
Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J
Publication Date: 2022

Variant appearance in text: TP53: 668C>T; P223L
PubMed Link: 35814426
Variant Present in the following documents:
  • DataSheet_1.xlsx, sheet 2
View BVdb publication page



Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications
Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX
Publication Date: 2022-06-15

Variant appearance in text: TP53: P223L
PubMed Link: 35705558
Variant Present in the following documents:
  • 41467_2022_30496_MOESM2_ESM.xls, sheet 1
View BVdb publication page



p53 and Zinc: A Malleable Relationship.

Frontiers In Molecular Biosciences
Ha, Jeung-Hoi JH; Prela, Orjola O; Carpizo, Darren R DR; Loh, Stewart N SN
Publication Date: 2022

Variant appearance in text: p53: P223L
PubMed Link: 35495631
Variant Present in the following documents:
  • Main text
  • fmolb-09-895887.pdf
View BVdb publication page



Identifying Phased Mutations and Complex Rearrangements in Human Prostate Cancer Cell Lines through Linked-Read Whole-Genome Sequencing.

Molecular Cancer Research : Mcr
Pham, Minh-Tam MT; Gupta, Anuj A; Gupta, Harshath H; Vaghasia, Ajay A; Skaist, Alyza A; Garrison, McKinzie A MA; Coulter, Jonathan B JB; Haffner, Michael C MC; Zheng, S Lilly SL; Xu, Jianfeng J; DeStefano Shields, Christina C; Isaacs, William B WB; Wheelan, Sarah J SJ; Nelson, William G WG; Yegnasubramanian, Srinivasan S
Publication Date: 2022-07-06

Variant appearance in text: TP53: 668C>T; P223L
PubMed Link: 35452513
Variant Present in the following documents:
  • mcr-21-0683_supplementary_tables_1-13_suppst1-13.xlsx, sheet 7
View BVdb publication page



Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.

Nature Biotechnology
Sánchez-Rivera, Francisco J FJ; Diaz, Bianca J BJ; Kastenhuber, Edward R ER; Schmidt, Henri H; Katti, Alyna A; Kennedy, Margaret M; Tem, Vincent V; Ho, Yu-Jui YJ; Leibold, Josef J; Paffenholz, Stella V SV; Barriga, Francisco M FM; Chu, Kevan K; Goswami, Sukanya S; Wuest, Alexandra N AN; Simon, Janelle M JM; Tsanov, Kaloyan M KM; Chakravarty, Debyani D; Zhang, Hongxin H; Leslie, Christina S CS; Lowe, Scott W SW; Dow, Lukas E LE
Publication Date: 2022-06

Variant appearance in text: TP53: P223L
PubMed Link: 35165384
Variant Present in the following documents:
  • NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 4
View BVdb publication page



Redox Sensitive Cysteine Residues as Crucial Regulators of Wild-Type and Mutant p53 Isoforms.

Cells
Butturini, Elena E; Butera, Giovanna G; Pacchiana, Raffaella R; Carcereri de Prati, Alessandra A; Mariotto, Sofia S; Donadelli, Massimo M
Publication Date: 2021-11-12

Variant appearance in text: p53: P223L
PubMed Link: 34831372
Variant Present in the following documents:
  • Main text
  • cells-10-03149.pdf
View BVdb publication page



Structural and Drug Targeting Insights on Mutant p53.

Cancers
Gomes, Ana Sara AS; Ramos, Helena H; Inga, Alberto A; Sousa, Emília E; Saraiva, Lucília L
Publication Date: 2021-07-03

Variant appearance in text: p53: P223L
PubMed Link: 34283062
Variant Present in the following documents:
  • Main text
  • cancers-13-03344.pdf
View BVdb publication page



A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports
Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM
Publication Date: 2021-07-12

Variant appearance in text: TP53: P223L; rs138983188
PubMed Link: 34253785
Variant Present in the following documents:
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 4
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 5
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 6
  • 41598_2021_93715_MOESM2_ESM.xlsx, sheet 10
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 2
  • 41598_2021_93715_MOESM2_ESM.xlsx, sheet 8
View BVdb publication page



Hypothermia Effectively Treats Tumors with Temperature-Sensitive p53 Mutations.

Cancer Research
Lu, Junhao J; Chen, Lihong L; Song, Zheng Z; Das, Mousumi M; Chen, Jiandong J
Publication Date: 2021-07-15

Variant appearance in text: p53: P223L
PubMed Link: 33687951
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gain-of-function p53 protein transferred via small extracellular vesicles promotes conversion of fibroblasts to a cancer-associated phenotype.

Cell Reports
Ma, Shaolin S; McGuire, Michael H MH; Mangala, Lingegowda S LS; Lee, Sanghoon S; Stur, Elaine E; Hu, Wen W; Bayraktar, Emine E; Villar-Prados, Alejandro A; Ivan, Cristina C; Wu, Sherry Y SY; Yokoi, Akira A; Dasari, Santosh K SK; Jennings, Nicholas B NB; Liu, Jinsong J; Lopez-Berestein, Gabriel G; Ram, Prahlad P; Sood, Anil K AK
Publication Date: 2021-02-09

Variant appearance in text: TP53: P223L
PubMed Link: 33567287
Variant Present in the following documents:
  • Main text
View BVdb publication page



Suberoylanilide hydroxamic acid enhances the radiosensitivity of lung cancer cells through acetylated wild-type and mutant p53-dependent modulation of mitochondrial apoptosis.

The Journal Of International Medical Research
Wu, Kan K; Chen, Xueqin X; Chen, Xufeng X; Zhang, Shirong S; Xu, Yasi Y; Xia, Bing B; Ma, Shenglin S
Publication Date: 2021-02

Variant appearance in text: p53: P223L
PubMed Link: 33557658
Variant Present in the following documents:
  • Main text
  • 10.1177_0300060520981545.pdf
View BVdb publication page



Development and validation of a multigene variant profiling assay to guide targeted and immuno therapy selection in solid tumors.

Plos One
Akolkar, Dadasaheb D; Patil, Darshana D; Srivastava, Navin N; Patil, Revati R; Datta, Vineet V; Apurwa, Sachin S; Yashwante, Nitin N; Dhasarathan, Raja R; Gosavi, Rahul R; John, Jinumary J; Khan, Shabishta S; Jadhav, Ninad N; Mene, Priti P; Ahire, Dhanashri D; Pawar, Sushant S; Bodke, Harshal H; Sahoo, Subhraline S; Nile, Arun A; Saindane, Dinesh D; Darokar, Harshal H; Devhare, Pradip P; Srinivasan, Ajay A; Datar, Rajan R
Publication Date: 2021

Variant appearance in text: TP53: P223L
PubMed Link: 33556149
Variant Present in the following documents:
  • pone.0246048.s008.xlsx, sheet 1
View BVdb publication page



STAT3 and p53: Dual Target for Cancer Therapy.

Biomedicines
Pham, Thu-Huyen TH; Park, Hyo-Min HM; Kim, Jinju J; Hong, Jin Tae JT; Yoon, Do-Young DY
Publication Date: 2020-12-21

Variant appearance in text: p53: P223L
PubMed Link: 33371351
Variant Present in the following documents:
  • Main text
  • biomedicines-08-00637.pdf
View BVdb publication page



Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.

Cell Death And Differentiation
Doffe, Flora F; Carbonnier, Vincent V; Tissier, Manon M; Leroy, Bernard B; Martins, Isabelle I; Mattsson, Johanna S M JSM; Micke, Patrick P; Pavlova, Sarka S; Pospisilova, Sarka S; Smardova, Jana J; Joerger, Andreas C AC; Wiman, Klas G KG; Kroemer, Guido G; Soussi, Thierry T
Publication Date: 2021-05

Variant appearance in text: rs138983188
PubMed Link: 33257846
Variant Present in the following documents:
  • 41418_2020_672_MOESM3_ESM.xlsx, sheet 4
View BVdb publication page



Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.

Cell Death And Differentiation
Doffe, Flora F; Carbonnier, Vincent V; Tissier, Manon M; Leroy, Bernard B; Martins, Isabelle I; Mattsson, Johanna S M JSM; Micke, Patrick P; Pavlova, Sarka S; Pospisilova, Sarka S; Smardova, Jana J; Joerger, Andreas C AC; Wiman, Klas G KG; Kroemer, Guido G; Soussi, Thierry T
Publication Date: 2021-05

Variant appearance in text: rs138983188
PubMed Link: 33257846
Variant Present in the following documents:
  • 41418_2020_672_MOESM3_ESM.xlsx, sheet 4
View BVdb publication page



LIMD2 Regulates Key Steps of Metastasis Cascade in Papillary Thyroid Cancer Cells via MAPK Crosstalk.

Cells
Araldi, Rodrigo Pinheiro RP; de Melo, Thatiana Correa TC; Levy, Débora D; de Souza, Dener Madeiro DM; Maurício, Beatriz B; Colozza-Gama, Gabriel Avelar GA; Bydlowski, Sergio Paulo SP; Peng, Hongzhuang H; Rauscher, Frank J FJ; Cerutti, Janete Maria JM
Publication Date: 2020-11-23

Variant appearance in text: TP53: P223L
PubMed Link: 33238381
Variant Present in the following documents:
  • Main text
  • cells-09-02522.pdf
View BVdb publication page



Anticancer Imidazoacridinone C-1311 is Effective in Androgen-Dependent and Androgen-Independent Prostate Cancer Cells.

Biomedicines
Niemira, Magdalena M; Borowa-Mazgaj, Barbara B; Bader, Samuel B SB; Moszyńska, Adrianna A; Ratajewski, Marcin M; Karaś, Kaja K; Kwaśniewski, Mirosław M; Krętowski, Adam A; Mazerska, Zofia Z; Hammond, Ester M EM; Skwarska, Anna A
Publication Date: 2020-08-19

Variant appearance in text: p53: P223L
PubMed Link: 32825120
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutant p53 induces Golgi tubulo-vesiculation driving a prometastatic secretome.

Nature Communications
Capaci, Valeria V; Bascetta, Lorenzo L; Fantuz, Marco M; Beznoussenko, Galina V GV; Sommaggio, Roberta R; Cancila, Valeria V; Bisso, Andrea A; Campaner, Elena E; Mironov, Alexander A AA; Wiśniewski, Jacek R JR; Ulloa Severino, Luisa L; Scaini, Denis D; Bossi, Fleur F; Lees, Jodi J; Alon, Noa N; Brunga, Ledia L; Malkin, David D; Piazza, Silvano S; Collavin, Licio L; Rosato, Antonio A; Bicciato, Silvio S; Tripodo, Claudio C; Mantovani, Fiamma F; Del Sal, Giannino G
Publication Date: 2020-08-07

Variant appearance in text: p53: P223L
PubMed Link: 32770028
Variant Present in the following documents:
  • Main text
View BVdb publication page



Gain-of-function mutant p53 in cancer progression and therapy.

Journal Of Molecular Cell Biology
Zhang, Cen C; Liu, Juan J; Xu, Dandan D; Zhang, Tianliang T; Hu, Wenwei W; Feng, Zhaohui Z
Publication Date: 2020-09-01

Variant appearance in text: p53: P223L
PubMed Link: 32722796
Variant Present in the following documents:
  • Main text
  • mjaa040.pdf
View BVdb publication page



Defining relative mutational difficulty to understand cancer formation.

Cell Discovery
Shan, Lin L; Yu, Jiao J; He, Zhengjin Z; Chen, Shishuang S; Liu, Mingxian M; Ding, Hongyu H; Xu, Liang L; Zhao, Jie J; Yang, Ailing A; Jiang, Hai H
Publication Date: 2020

Variant appearance in text: p53: P223L
PubMed Link: 32704382
Variant Present in the following documents:
  • 41421_2020_177_MOESM5_ESM.xlsx, sheet 1
  • 41421_2020_177_MOESM4_ESM.xlsx, sheet 1
  • 41421_2020_177_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Influences of TP53 and the anti-aging DDR1 receptor in controlling Raf/MEK/ERK and PI3K/Akt expression and chemotherapeutic drug sensitivity in prostate cancer cell lines.

Aging
Chappell, William H WH; Candido, Saverio S; Abrams, Stephen L SL; Akula, Shaw M SM; Steelman, Linda S LS; Martelli, Alberto M AM; Ratti, Stefano S; Cocco, Lucio L; Cervello, Melchiorre M; Montalto, Giuseppe G; Nicoletti, Ferdinando F; Libra, Massimo M; McCubrey, James A JA
Publication Date: 2020-06-03

Variant appearance in text: TP53: P223L
PubMed Link: 32492656
Variant Present in the following documents:
  • Main text
  • aging-12-103377.pdf
View BVdb publication page



Study of Caspase 8 mutation in oral cancer and adjacent precancer tissues and implication in progression.

Plos One
Singh, Richa R; Das, Shreya S; Datta, Sila S; Mazumdar, Anjana A; Biswas, Nidhan K NK; Maitra, Arindam A; Majumder, Partha P PP; Ghose, Sandip S; Roy, Bidyut B
Publication Date: 2020

Variant appearance in text: TP53: P223L
PubMed Link: 32492030
Variant Present in the following documents:
  • pone.0233058.s001.xlsx, sheet 21
View BVdb publication page



Phase and context shape the function of composite oncogenic mutations.

Nature
Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS
Publication Date: 2020-06

Variant appearance in text: TP53: P223L
PubMed Link: 32461694
Variant Present in the following documents:
  • NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2
View BVdb publication page



Coding and noncoding somatic mutations in candidate genes in basal cell carcinoma.

Scientific Reports
Maturo, Maria Giovanna MG; Rachakonda, Sivaramakrishna S; Heidenreich, Barbara B; Pellegrini, Cristina C; Srinivas, Nalini N; Requena, Celia C; Serra-Guillen, Carlos C; Llombart, Beatriz B; Sanmartin, Onofre O; Guillen, Carlos C; Di Nardo, Lucia L; Peris, Ketty K; Fargnoli, Maria Concetta MC; Nagore, Eduardo E; Kumar, Rajiv R
Publication Date: 2020-05-14

Variant appearance in text: TP53: 668C>T; P223L
PubMed Link: 32409749
Variant Present in the following documents:
  • 41598_2020_65057_MOESM2_ESM.xlsx, sheet 3
View BVdb publication page



Combinatorial Therapies in Thyroid Cancer: An Overview of Preclinical and Clinical Progresses.

Cells
Laetitia, Gheysen G; Sven, Saussez S; Fabrice, Journe J
Publication Date: 2020-03-30

Variant appearance in text: TP53: 668C>T
PubMed Link: 32235612
Variant Present in the following documents:
  • Main text
  • cells-09-00830.pdf
View BVdb publication page



The Quantitative-Phase Dynamics of Apoptosis and Lytic Cell Death.

Scientific Reports
Vicar, Tomas T; Raudenska, Martina M; Gumulec, Jaromir J; Balvan, Jan J
Publication Date: 2020-01-31

Variant appearance in text: p53: P223L
PubMed Link: 32005874
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_58474.pdf
View BVdb publication page



False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases.

Plos One
Kim, Young-Ho YH; Song, Yura Y; Kim, Jong-Kwang JK; Kim, Tae-Min TM; Sim, Hye Won HW; Kim, Hyung-Lae HL; Jang, Hyonchol H; Kim, Young-Woo YW; Hong, Kyeong-Man KM
Publication Date: 2019

Variant appearance in text: TP53: 668C>T; P223L
PubMed Link: 31513681
Variant Present in the following documents:
  • pone.0222535.s006.xlsx, sheet 1
View BVdb publication page



The Δ133p53β isoform promotes an immunosuppressive environment leading to aggressive prostate cancer.

Cell Death & Disease
Kazantseva, Marina M; Mehta, Sunali S; Eiholzer, Ramona A RA; Gimenez, Gregory G; Bowie, Sara S; Campbell, Hamish H; Reily-Bell, Ashley L AL; Roth, Imogen I; Ray, Sankalita S; Drummond, Catherine J CJ; Reid, Glen G; Joruiz, Sebastien M SM; Wiles, Anna A; Morrin, Helen R HR; Reader, Karen L KL; Hung, Noelyn A NA; Baird, Margaret A MA; Slatter, Tania L TL; Braithwaite, Antony W AW
Publication Date: 2019-08-20

Variant appearance in text: TP53: P223L
PubMed Link: 31431617
Variant Present in the following documents:
  • Main text
  • 41419_2019_Article_1861.pdf
View BVdb publication page



p53 mutant-type in human prostate cancer cells determines the sensitivity to phenethyl isothiocyanate induced growth inhibition.

Journal Of Experimental & Clinical Cancer Research : Cr
Aggarwal, Monika M; Saxena, Rahul R; Asif, Nasir N; Sinclair, Elizabeth E; Tan, Judy J; Cruz, Idalia I; Berry, Deborah D; Kallakury, Bhaskar B; Pham, Quynhchi Q; Wang, Thomas T Y TTY; Chung, Fung-Lung FL
Publication Date: 2019-07-15

Variant appearance in text: p53: P223L
PubMed Link: 31307507
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutant p53 amplifies a dynamin-1/APPL1 endosome feedback loop that regulates recycling and migration.

The Journal Of Cell Biology
Lakoduk, Ashley M AM; Roudot, Philippe P; Mettlen, Marcel M; Grossman, Heather M HM; Schmid, Sandra L SL; Chen, Ping-Hung PH
Publication Date: 2019-06-03

Variant appearance in text: p53: P223L
PubMed Link: 31043431
Variant Present in the following documents:
  • Main text
  • JCB_201810183_sm.pdf
  • JCB_201810183.pdf
View BVdb publication page



Comprehensive genomic and immunological characterization of Chinese non-small cell lung cancer patients.

Nature Communications
Zhang, Xu-Chao XC; Wang, Jun J; Shao, Guo-Guang GG; Wang, Qun Q; Qu, Xiaotao X; Wang, Bo B; Moy, Christopher C; Fan, Yue Y; Albertyn, Zayed Z; Huang, Xiayu X; Zhang, Jingyu J; Qiu, Yang Y; Platero, Suso S; Lorenzi, Matthew V MV; Zudaire, Enrique E; Yang, Jennifer J; Cheng, Ying Y; Xu, Lin L; Wu, Yi-Long YL
Publication Date: 2019-04-16

Variant appearance in text: rs138983188
PubMed Link: 30992440
Variant Present in the following documents:
  • 41467_2019_9762_MOESM13_ESM.xlsx, sheet 1
View BVdb publication page



From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.

Cold Spring Harbor Molecular Case Studies
Quinn, Emily A EA; Maciaszek, Jamie L JL; Pinto, Emilia M EM; Phillips, Aaron H AH; Berdy, David D; Khandwala, Mohammad M; Upadhyaya, Santhosh A SA; Zambetti, Gerard P GP; Kriwacki, Richard W RW; Ellison, David W DW; Nichols, Kim E KE; Kesserwan, Chimene C
Publication Date: 2019-08

Variant appearance in text: TP53: 668C>T; Pro223Leu
PubMed Link: 30886117
Variant Present in the following documents:
  • supp_mcs.a003921_Supplemental_Table_1a.xlsx, sheet 1
View BVdb publication page



EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis.

The Embo Journal
Zhao, Yu Y; Ding, Liya L; Wang, Dejie D; Ye, Zhenqing Z; He, Yundong Y; Ma, Linlin L; Zhu, Runzhi R; Pan, Yunqian Y; Wu, Qiang Q; Pang, Kun K; Hou, Xiaonan X; Weroha, Saravut J SJ; Han, Conghui C; Coleman, Roger R; Coleman, Ilsa I; Karnes, R Jeffery RJ; Zhang, Jun J; Nelson, Peter S PS; Wang, Liguo L; Huang, Haojie H
Publication Date: 2019-03-01

Variant appearance in text: p53: P223L
PubMed Link: 30723117
Variant Present in the following documents:
  • Main text
View BVdb publication page



Salvation of the fallen angel: Reactivating mutant p53.

British Journal Of Pharmacology
Li, Yang Y; Wang, Zhuoyi Z; Chen, Yuchen Y; Petersen, Robert B RB; Zheng, Ling L; Huang, Kun K
Publication Date: 2019-04

Variant appearance in text: p53: P223L
PubMed Link: 30632144
Variant Present in the following documents:
  • Main text
View BVdb publication page



Potent Anti-Cancer Properties of Phthalimide-Based Curcumin Derivatives on Prostate Tumor Cells.

International Journal Of Molecular Sciences
Belluti, Silvia S; Orteca, Giulia G; Semeghini, Valentina V; Rigillo, Giovanna G; Parenti, Francesca F; Ferrari, Erika E; Imbriano, Carol C
Publication Date: 2018-12-21

Variant appearance in text: p53: P223L
PubMed Link: 30577600
Variant Present in the following documents:
  • Main text
View BVdb publication page



Regulators of Oncogenic Mutant TP53 Gain of Function.

Cancers
Yamamoto, Satomi S; Iwakuma, Tomoo T
Publication Date: 2018-12-20

Variant appearance in text: p53: P223L
PubMed Link: 30577483
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutant p53 in cancer therapy-the barrier or the path.

Journal Of Molecular Cell Biology
Zhou, Xiang X; Hao, Qian Q; Lu, Hua H
Publication Date: 2019-04-01

Variant appearance in text: p53: P223L
PubMed Link: 30508182
Variant Present in the following documents:
  • Main text
  • mjy072.pdf
View BVdb publication page