Publications:

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Androgen Receptor Activation Induces Senescence in Thyroid Cancer Cells.

Cancers

Gupta, Anvita A; Carnazza, Michelle M; Jones, Melanie M; Darzynkiewicz, Zbigniew Z; Halicka, Dorota D; O'Connell, Timmy T; Zhao, Hong H; Dadafarin, Sina S; Shin, Edward E; Schwarcz, Monica D MD; Moscatello, Augustine A; Tiwari, Raj K RK; Geliebter, Jan J

Publication Date: 2023-04-07

Variant appearance in text: p53: Arg213Arg

PubMed Link: 37190127

Variant Present in the following documents:

• Main text
• cancers-15-02198.pdf

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Decellularized extracellular matrix as scaffold for cancer organoid cultures of colorectal peritoneal metastases.

Journal Of Molecular Cell Biology

Varinelli, Luca L; Guaglio, Marcello M; Brich, Silvia S; Zanutto, Susanna S; Belfiore, Antonino A; Zanardi, Federica F; Iannelli, Fabio F; Oldani, Amanda A; Costa, Elisa E; Chighizola, Matteo M; Lorenc, Ewelina E; Minardi, Simone P SP; Fortuzzi, Stefano S; Filugelli, Martina M; Garzone, Giovanna G; Pisati, Federica F; Vecchi, Manuela M; Pruneri, Giancarlo G; Kusamura, Shigeki S; Baratti, Dario D; Cattaneo, Laura L; Parazzoli, Dario D; Podestà, Alessandro A; Milione, Massimo M; Deraco, Marcello M; Pierotti, Marco A MA; Gariboldi, Manuela M

Publication Date: 2022-12-02

Variant appearance in text: TP53: R213R

PubMed Link: 36460033

Variant Present in the following documents:

• mjac064_supplemental_file.pdf

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Targeted genetic and epigenetic profiling of esophageal adenocarcinomas and non-dysplastic Barrett's esophagus.

Clinical Epigenetics

Pinto, Rita R; Hauge, Tobias T; Jeanmougin, Marine M; Pharo, Heidi D HD; Kresse, Stine H SH; Honne, Hilde H; Winge, Sara B SB; Five, May-Britt MB; Kumar, Theresa T; Mala, Tom T; Hauge, Truls T; Johnson, Egil E; Lind, Guro E GE

Publication Date: 2022-06-14

Variant appearance in text: TP53: R213R

PubMed Link: 35701814

Variant Present in the following documents:

• Main text
• 13148_2022_Article_1287.pdf

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Association between germline pathogenic variants and breast cancer risk in Japanese women: The HERPACC study.

Cancer Science

Kasugai, Yumiko Y; Kohmoto, Tomohiro T; Taniyama, Yukari Y; Koyanagi, Yuriko N YN; Usui, Yoshiaki Y; Iwase, Madoka M; Oze, Isao I; Yamaguchi, Rui R; Ito, Hidemi H; Imoto, Issei I; Matsuo, Keitaro K

Publication Date: 2022-04

Variant appearance in text: TP53: R213R

PubMed Link: 35218119

Variant Present in the following documents:

• CAS-113-1451-s002.xlsx, sheet 1

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Acquired somatic variants in inherited myeloid malignancies.

Leukemia

Armes, Hannah H; Rio-Machin, Ana A; Krizsán, Szilvia S; Bödör, Csaba C; Kaya, Fadimana F; Bewicke-Copley, Findlay F; Alnajar, Jenna J; Walne, Amanda A; Péterffy, Borbála B; Tummala, Hemanth H; Rouault-Pierre, Kevin K; Dokal, Inderjeet I; Vulliamy, Tom T; Fitzgibbon, Jude J

Publication Date: 2022-05

Variant appearance in text: TP53: R213R

PubMed Link: 35140362

Variant Present in the following documents:

• 41375_2022_1515_MOESM4_ESM.xlsx, sheet 1

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TP53 Mutation Is a Prognostic Factor in Lower Grade Glioma and May Influence Chemotherapy Efficacy.

Cancers

Noor, Humaira H; Briggs, Nancy E NE; McDonald, Kerrie L KL; Holst, Jeff J; Vittorio, Orazio O

Publication Date: 2021-10-26

Variant appearance in text: TP53: R213R

PubMed Link: 34771529

Variant Present in the following documents:

• Main text

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Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients.

Scientific Reports

Muendlein, Axel A; Geiger, Kathrin K; Gaenger, Stella S; Dechow, Tobias T; Nonnenbroich, Christoph C; Leiherer, Andreas A; Drexel, Heinz H; Gaumann, Andreas A; Jagla, Wolfgang W; Winder, Thomas T; Mayer, Frank F; Decker, Thomas T

Publication Date: 2021-03-24

Variant appearance in text: TP53: Arg213Arg

PubMed Link: 33762647

Variant Present in the following documents:

• Main text
• 41598_2021_Article_86238.pdf

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The mutational load and a T-cell inflamed tumour phenotype identify ovarian cancer patients rendering tumour-reactive T cells from PD-1+ tumour-infiltrating lymphocytes.

British Journal Of Cancer

Salas-Benito, Diego D; Conde, Enrique E; Tamayo-Uria, Ibon I; Mancheño, Uxua U; Elizalde, Edurne E; Garcia-Ros, David D; Aramendia, Jose M JM; Muruzabal, Juan C JC; Alcaide, Julia J; Guillen-Grima, Francisco F; Minguez, Jose A JA; Amores-Tirado, Jose J; Gonzalez-Martin, Antonio A; Sarobe, Pablo P; Lasarte, Juan J JJ; Ponz-Sarvise, Mariano M; De Andrea, Carlos E CE; Hervas-Stubbs, Sandra S

Publication Date: 2021-03

Variant appearance in text: TP53: Arg213Arg

PubMed Link: 33402737

Variant Present in the following documents:

• 41416_2020_1218_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Impact of genetic alterations on outcomes of patients with stage I nonsmall cell lung cancer: An analysis of the cancer genome atlas data.

Cancer Medicine

Xu, Song S; Wang, Yanye Y; Ren, Fan F; Li, Xiongfei X; Ren, Dian D; Dong, Ming M; Chen, Gang G; Song, Zuoqing Z; Chen, Jun J

Publication Date: 2020-10

Variant appearance in text: TP53: R213R

PubMed Link: 32857918

Variant Present in the following documents:

• Main text
• CAM4-9-7686.pdf

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Genomic characterization of malignant progression in neoplastic pancreatic cysts.

Nature Communications

Noë, Michaël M; Niknafs, Noushin N; Fischer, Catherine G CG; Hackeng, Wenzel M WM; Beleva Guthrie, Violeta V; Hosoda, Waki W; Debeljak, Marija M; Papp, Eniko E; Adleff, Vilmos V; White, James R JR; Luchini, Claudio C; Pea, Antonio A; Scarpa, Aldo A; Butturini, Giovanni G; Zamboni, Giuseppe G; Castelli, Paola P; Hong, Seung-Mo SM; Yachida, Shinichi S; Hiraoka, Nobuyoshi N; Gill, Anthony J AJ; Samra, Jaswinder S JS; Offerhaus, G Johan A GJA; Hoorens, Anne A; Verheij, Joanne J; Jansen, Casper C; Adsay, N Volkan NV; Jiang, Wei W; Winter, Jordan J; Albores-Saavedra, Jorge J; Terris, Benoit B; Thompson, Elizabeth D ED; Roberts, Nicholas J NJ; Hruban, Ralph H RH; Karchin, Rachel R; Scharpf, Robert B RB; Brosens, Lodewijk A A LAA; Velculescu, Victor E VE; Wood, Laura D LD

Publication Date: 2020-08-14

Variant appearance in text: TP53: R213R

PubMed Link: 32796935

Variant Present in the following documents:

• 41467_2020_17917_MOESM7_ESM.xlsx, sheet 1

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Associations among smoking, MGMT hypermethylation, TP53-mutations, and relapse in head and neck squamous cell carcinoma.

Plos One

Matsuda, Shinichi S; Mafune, Aki A; Kohda, Nagisa N; Hama, Takanori T; Urashima, Mitsuyoshi M

Publication Date: 2020

Variant appearance in text: TP53: R213R

PubMed Link: 32324779

Variant Present in the following documents:

• Main text
• pone.0231932.pdf

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Molecular characterization of low grade and high grade bladder cancer.

Plos One

Apollo, Alessandro A; Ortenzi, Valerio V; Scatena, Cristian C; Zavaglia, Katia K; Aretini, Paolo P; Lessi, Francesca F; Franceschi, Sara S; Tomei, Sara S; Sepich, Carlo Alberto CA; Viacava, Paolo P; Mazzanti, Chiara Maria CM; Naccarato, Antonio Giuseppe AG

Publication Date: 2019

Variant appearance in text: TP53: R213R

PubMed Link: 30650148

Variant Present in the following documents:

• pone.0210635.s002.xlsx, sheet 3

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Prognostic effect of whole chromosomal aberration signatures in standard-risk, non-WNT/non-SHH medulloblastoma: a retrospective, molecular analysis of the HIT-SIOP PNET 4 trial.

The Lancet. Oncology

Goschzik, Tobias T; Schwalbe, Edward C EC; Hicks, Debbie D; Smith, Amanda A; Zur Muehlen, Anja A; Figarella-Branger, Dominique D; Doz, François F; Rutkowski, Stefan S; Lannering, Birgitta B; Pietsch, Torsten T; Clifford, Steven C SC

Publication Date: 2018-12

Variant appearance in text: TP53: R213R

PubMed Link: 30392813

Variant Present in the following documents:

• mmc1.pdf

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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: TP53: R213R; rs397516436

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

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Sources of discordance among germ-line variant classifications in ClinVar.

Genetics In Medicine : Official Journal Of The American College Of Medical Genetics

Yang, Shan S; Lincoln, Stephen E SE; Kobayashi, Yuya Y; Nykamp, Keith K; Nussbaum, Robert L RL; Topper, Scott S

Publication Date: 2017-10

Variant appearance in text: N/A

PubMed Link: 28569743

Variant Present in the following documents:

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Targeted exome sequencing reveals distinct pathogenic variants in Iranians with colorectal cancer.

Oncotarget

Ashktorab, Hassan H; Mokarram, Pooneh P; Azimi, Hamed H; Olumi, Hasti H; Varma, Sudhir S; Nickerson, Michael L ML; Brim, Hassan H

Publication Date: 2017-01-31

Variant appearance in text: TP53: R213R

PubMed Link: 28002797

Variant Present in the following documents:

• oncotarget-08-7852-s002.xlsx, sheet 1

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Expression profiling of cutaneous squamous cell carcinoma with perineural invasion implicates the p53 pathway in the process.

Scientific Reports

Warren, Timothy A TA; Broit, Natasa N; Simmons, Jacinta L JL; Pierce, Carly J CJ; Chawla, Sharad S; Lambie, Duncan L J DL; Quagliotto, Gary G; Brown, Ian S IS; Parsons, Peter G PG; Panizza, Benedict J BJ; Boyle, Glen M GM

Publication Date: 2016-09-26

Variant appearance in text: TP53: R213R

PubMed Link: 27665737

Variant Present in the following documents:

• srep34081-s1.pdf

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Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases.

International Journal Of Cancer

Løes, Inger Marie IM; Immervoll, Heike H; Sorbye, Halfdan H; Angelsen, Jon-Helge JH; Horn, Arild A; Knappskog, Stian S; Lønning, Per Eystein PE

Publication Date: 2016-08-01

Variant appearance in text: TP53: R213R

PubMed Link: 26991344

Variant Present in the following documents:

• IJC-139-647-s003.xls, sheet 1

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Distinct effects of alcohol consumption and smoking on genetic alterations in head and neck carcinoma.

Plos One

Urashima, Mitsuyoshi M; Hama, Takanori T; Suda, Toshihito T; Suzuki, Yutaka Y; Ikegami, Masahiro M; Sakanashi, Chikako C; Akutsu, Taisuke T; Amagaya, Suguru S; Horiuchi, Kazuhumi K; Imai, Yu Y; Mezawa, Hidetoshi H; Noya, Miki M; Nakashima, Akio A; Mafune, Aki A; Kato, Takakuni T; Kojima, Hiromi H

Publication Date: 2013

Variant appearance in text: TP53: R213R

PubMed Link: 24278325

Variant Present in the following documents:

• Main text
• pone.0080828.pdf

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Clonal analysis in recurrent astrocytic, oligoastrocytic and oligodendroglial tumors implicates IDH1- mutation as common tumor initiating event.

Plos One

Lass, Ulrike U; Nümann, Astrid A; von Eckardstein, Kajetan K; Kiwit, Jürgen J; Stockhammer, Florian F; Horaczek, Jörn A JA; Veelken, Julian J; Herold-Mende, Christel C; Jeuken, Judith J; von Deimling, Andreas A; Mueller, Wolf W

Publication Date: 2012

Variant appearance in text: TP53: R213R

PubMed Link: 22844452

Variant Present in the following documents:

• pone.0041298.s001.xls, sheet 1

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Multiplex amplification coupled with COLD-PCR and high resolution melting enables identification of low-abundance mutations in cancer samples with low DNA content.

The Journal Of Molecular Diagnostics : Jmd

Milbury, Coren A CA; Chen, Clark C CC; Mamon, Harvey H; Liu, Pingfang P; Santagata, Sandro S; Makrigiorgos, G Mike GM

Publication Date: 2011-03

Variant appearance in text: TP53: R213R

PubMed Link: 21354058

Variant Present in the following documents:

• Main text

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Analysis of R213R and 13494 g-->a polymorphisms of the p53 gene in individuals with esophagitis, intestinal metaplasia of the cardia and Barrett's Esophagus compared with a control group.

Genomic Medicine

Pilger, Diogo André DA; Lopez, Patrícia Luciana da Costa PL; Segal, Fábio F; Leistner-Segal, Sandra S

Publication Date: 2007

Variant appearance in text: TP53: R213R

PubMed Link: 18923929

Variant Present in the following documents:

• Main text

View BVdb publication page

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p16INK4a is a prognostic marker in resected ductal pancreatic cancer: an analysis of p16INK4a, p53, MDM2, an Rb.

Annals Of Surgery

Gerdes, Berthold B; Ramaswamy, Annette A; Ziegler, Andreas A; Lang, Sven A SA; Kersting, Michael M; Baumann, Renate R; Wild, Anja A; Moll, Roland R; Rothmund, Matthias M; Bartsch, Detlef K DK

Publication Date: 2002-01

Variant appearance in text: p53: R213R

PubMed Link: 11753042

Variant Present in the following documents:

• Main text

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Germline TP53 alterations in Finnish breast cancer families are rare and occur at conserved mutation-prone sites.

British Journal Of Cancer

Rapakko, K K; Allinen, M M; Syrjäkoski, K K; Vahteristo, P P; Huusko, P P; Vähäkangas, K K; Eerola, H H; Kainu, T T; Kallioniemi, O P OP; Nevanlinna, H H; Winqvist, R R

Publication Date: 2001-01-05

Variant appearance in text: TP53: Arg213Arg

PubMed Link: 11139324

Variant Present in the following documents:

• 84-6691530a.pdf

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