Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study.
Bmc Cancer
Huang, Qiang Q; Li, Feiran F; Ji, Mengyou M; Lin, Lan L; Hu, Chunyan C
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.
Cancer Research Communications
White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C
Publication Date: 2022-09
Variant appearance in text: TP53: 566C>T; A189V; rs121912665
Targeted next generation sequencing of circulating tumor DNA provides prognostic information for management in breast cancer patients.
Annals Of Translational Medicine
Shim, Hyoeun H; Kwon, Min Jeong MJ; Park, In Hae IH; Kim, Min Kyeong MK; Cho, Eun-Hae EH; Lee, Junnam J; Lee, Seung-Tae ST; Sim, Sung Hoon SH; Lee, Keun Seok KS; Kim, Yun-Hee YH; Kim, Seok-Ki SK; Lee, Eun Sook ES; Kong, Sun-Young SY
Implication and Influence of Multigene Panel Testing with Genetic Counseling in Korean Patients with BRCA1/2 Mutation-Negative Breast Cancer.
Cancer Research And Treatment
Park, Ji Soo JS; Shin, Saeam S; Lee, Yoon Jung YJ; Lee, Seung-Tae ST; Nam, Eun Ji EJ; Han, Jung Woo JW; Lee, Sun Hwa SH; Kim, Tae Il TI; Park, Hyung Seok HS
Publication Date: 2022-10
Variant appearance in text: TP53: 566C>T; Ala189Val; rs121912665
Clinical Features of Breast Cancer in South Korean Patients with Germline TP53 Gene Mutations.
Journal Of Breast Cancer
Alyami, Hassan H; Yoo, Tae Kyung TK; Cheun, Jong Ho JH; Lee, Han Byoel HB; Jung, Sung Mi SM; Ryu, Jai Min JM; Bae, Soong June SJ; Jeong, Joon J; Yoon, Chang Ik CI; Ahn, Juneyoung J; Paik, Pill Sun PS; Cho, Min Kyung MK; Park, Woo Chan WC
Whole Exome Sequencing Identifies Novel Genetic Alterations in Patients with Pheochromocytoma/Paraganglioma.
Endocrinology And Metabolism (Seoul, Korea)
Seo, Soo Hyun SH; Kim, Jung Hee JH; Kim, Man Jin MJ; Cho, Sung Im SI; Kim, Su Jin SJ; Kang, Hyein H; Shin, Chan Soo CS; Park, Sung Sup SS; Lee, Kyu Eun KE; Seong, Moon-Woo MW
Publication Date: 2020-12
Variant appearance in text: TP53: 566C>T; Ala189Val
Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.
Cell Death And Differentiation
Doffe, Flora F; Carbonnier, Vincent V; Tissier, Manon M; Leroy, Bernard B; Martins, Isabelle I; Mattsson, Johanna S M JSM; Micke, Patrick P; Pavlova, Sarka S; Pospisilova, Sarka S; Smardova, Jana J; Joerger, Andreas C AC; Wiman, Klas G KG; Kroemer, Guido G; Soussi, Thierry T
Publication Date: 2021-05
Variant appearance in text: TP53: 566C>T; rs121912665
Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.
Cell Death And Differentiation
Doffe, Flora F; Carbonnier, Vincent V; Tissier, Manon M; Leroy, Bernard B; Martins, Isabelle I; Mattsson, Johanna S M JSM; Micke, Patrick P; Pavlova, Sarka S; Pospisilova, Sarka S; Smardova, Jana J; Joerger, Andreas C AC; Wiman, Klas G KG; Kroemer, Guido G; Soussi, Thierry T
Publication Date: 2021-05
Variant appearance in text: TP53: 566C>T; rs121912665
Clinical Application of Targeted Deep Sequencing in Metastatic Colorectal Cancer Patients: Actionable Genomic Alteration in K-MASTER Project.
Cancer Research And Treatment
Lee, Youngwoo Y; Lee, Soohyeon S; Sung, Jae Sook JS; Chung, Hee-Joon HJ; Lim, Ah-Reum AR; Kim, Ju Won JW; Choi, Yoon Ji YJ; Park, Kyong Hwa KH; Kim, Yeul Hong YH
Criteria of the German Consortium for Hereditary Breast and Ovarian Cancer for the Classification of Germline Sequence Variants in Risk Genes for Hereditary Breast and Ovarian Cancer.
Geburtshilfe Und Frauenheilkunde
Wappenschmidt, Barbara B; Hauke, Jan J; Faust, Ulrike U; Niederacher, Dieter D; Wiesmüller, Lisa L; Schmidt, Gunnar G; Groß, Evi E; Gehrig, Andrea A; Sutter, Christian C; Ramser, Juliane J; Rump, Andreas A; Arnold, Norbert N; Meindl, Alfons A
Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer.
Cell Reports
Lee, Sanghoon S; Zhao, Li L; Rojas, Christine C; Bateman, Nicholas W NW; Yao, Hui H; Lara, Olivia D OD; Celestino, Joseph J; Morgan, Margaret B MB; Nguyen, Tri V TV; Conrads, Kelly A KA; Rangel, Kelly M KM; Dood, Robert L RL; Hajek, Richard A RA; Fawcett, Gloria L GL; Chu, Randy A RA; Wilson, Katlin K; Loffredo, Jeremy L JL; Viollet, Coralie C; Jazaeri, Amir A AA; Dalgard, Clifton L CL; Mao, Xizeng X; Song, Xingzhi X; Zhou, Ming M; Hood, Brian L BL; Banskota, Nirad N; Wilkerson, Matthew D MD; Te, Jerez J; Soltis, Anthony R AR; Roman, Kristin K; Dunn, Andrew A; Cordover, David D; Eterovic, Agda Karina AK; Liu, Jinsong J; Burks, Jared K JK; Baggerly, Keith A KA; Fleming, Nicole D ND; Lu, Karen H KH; Westin, Shannon N SN; Coleman, Robert L RL; Mills, Gordon B GB; Casablanca, Yovanni Y; Zhang, Jianhua J; Conrads, Thomas P TP; Maxwell, George L GL; Futreal, P Andrew PA; Sood, Anil K AK
Comprehensive pharmacogenomic characterization of gastric cancer.
Genome Medicine
Sa, Jason K JK; Hong, Jung Yong JY; Lee, In-Kyoung IK; Kim, Ju-Sun JS; Sim, Moon-Hee MH; Kim, Ha Jung HJ; An, Ji Yeong JY; Sohn, Tae Sung TS; Lee, Joon Ho JH; Bae, Jae Moon JM; Kim, Sung S; Kim, Kyoung-Mee KM; Kim, Seung Tae ST; Park, Se Hoon SH; Park, Joon Oh JO; Lim, Ho Yeong HY; Kang, Won Ki WK; Her, Nam-Gu NG; Lee, Yeri Y; Cho, Hee Jin HJ; Shin, Yong Jae YJ; Kim, Misuk M; Koo, Harim H; Kim, Mirinae M; Seo, Yun Jee YJ; Kim, Ja Yeon JY; Choi, Min-Gew MG; Nam, Do-Hyun DH; Lee, Jeeyun J
From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.
Cold Spring Harbor Molecular Case Studies
Quinn, Emily A EA; Maciaszek, Jamie L JL; Pinto, Emilia M EM; Phillips, Aaron H AH; Berdy, David D; Khandwala, Mohammad M; Upadhyaya, Santhosh A SA; Zambetti, Gerard P GP; Kriwacki, Richard W RW; Ellison, David W DW; Nichols, Kim E KE; Kesserwan, Chimene C
Publication Date: 2019-08
Variant appearance in text: TP53: 566C>T; Ala189Val
Integrative molecular profiling identifies a novel cluster of estrogen receptor-positive breast cancer in very young women.
Cancer Science
Park, Charny C; Yoon, Kyong-Ah KA; Kim, Jihyun J; Park, In Hae IH; Park, Soo Jin SJ; Kim, Min Kyeong MK; Jang, Wooyeong W; Cho, Soo Young SY; Park, Boyoung B; Kong, Sun-Young SY; Lee, Eun Sook ES
Publication Date: 2019-05
Variant appearance in text: TP53: 566C>T; A189V; rs121912665
Assessing the Pathogenicity, Penetrance, and Expressivity of Putative Disease-Causing Variants in a Population Setting.
American Journal Of Human Genetics
Wright, Caroline F CF; West, Ben B; Tuke, Marcus M; Jones, Samuel E SE; Patel, Kashyap K; Laver, Thomas W TW; Beaumont, Robin N RN; Tyrrell, Jessica J; Wood, Andrew R AR; Frayling, Timothy M TM; Hattersley, Andrew T AT; Weedon, Michael N MN
Publication Date: 2019-02-07
Variant appearance in text: TP53: A189V; rs121912665
Variable population prevalence estimates of germline TP53 variants: A gnomAD-based analysis.
Human Mutation
de Andrade, Kelvin C KC; Frone, Megan N MN; Wegman-Ostrosky, Talia T; Khincha, Payal P PP; Kim, Jung J; Amadou, Amina A; Santiago, Karina M KM; Fortes, Fernanda P FP; Lemonnier, Nathanaël N; Mirabello, Lisa L; Stewart, Douglas R DR; Hainaut, Pierre P; Kowalski, Luiz P LP; Savage, Sharon A SA; Achatz, Maria I MI
Erratum: Prevalence of germline BRCA mutations among women with carcinoma of the peritoneum or fallopian tube.
Journal Of Gynecologic Oncology
Choi, Min Chul MC; Bae, Jin Sik JS; Jung, Sang Geun SG; Park, Hyun H; Joo, Won Duk WD; Song, Seung Hun SH; Lee, Chan C; Kim, Ji Ho JH; Lee, Ki Chan KC; Lee, Sunghoon S; Lee, Je Ho JH
Publication Date: 2018-09
Variant appearance in text: TP53: 566C>T; Ala189Val
Prevalence of germline BRCA mutations among women with carcinoma of the peritoneum or fallopian tube.
Journal Of Gynecologic Oncology
Choi, Min Chul MC; Bae, Jin Sik JS; Jung, Sang Geun SG; Park, Hyun H; Joo, Won Duk WD; Song, Seung Hun SH; Lee, Chan C; Kim, Ji Ho JH; Lee, Ki Chan KC; Lee, Sunghoon S; Lee, Je Ho JH
Publication Date: 2018-07
Variant appearance in text: TP53: 566C>T; Ala189Val
Mutational profiling can identify laryngeal dysplasia at risk of progression to invasive carcinoma.
Scientific Reports
Manterola, Lorea L; Aguirre, Pablo P; Larrea, Erika E; Arestín, María M; Gaafar, Ayman A; Elorriaga, Kepa K; Goicoechea, Ibai I; Armesto, María M; Fernández-Mercado, Marta M; Zabalza, Ignacio I; López-Duque, Juan Carlos JC; Larruskain, Ekhiñe E; Sistiaga, Jon Alexander JA; Landa, Mikel M; Zabala, Aitor A; Santaolalla, Francisco F; Municio, José Antonio JA; Ispizua, Ángel Á; García-Pedrero, Juana María JM; Rodrigo, Juan Pablo JP; Lawrie, Charles Henderson CH
Selective identification of somatic mutations in pancreatic cancer cells through a combination of next-generation sequencing of plasma DNA using molecular barcodes and a bioinformatic variant filter.
Profiling tumour heterogeneity through circulating tumour DNA in patients with pancreatic cancer.
Oncotarget
Adamo, Patricia P; Cowley, Caroline M CM; Neal, Christopher P CP; Mistry, Vilas V; Page, Karen K; Dennison, Ashley R AR; Isherwood, John J; Hastings, Robert R; Luo, JinLi J; Moore, David A DA; Howard, Pringle J PJ; Miguel, Martins L ML; Pritchard, Catrin C; Manson, Margaret M; Shaw, Jacqui A JA
Application of a multi-gene next-generation sequencing panel to a non-invasive oesophageal cell-sampling device to diagnose dysplastic Barrett's oesophagus.
The Journal Of Pathology. Clinical Research
Katz-Summercorn, Annalise A; Anand, Shubha S; Ingledew, Sophie S; Huang, Yuanxue Y; Roberts, Thomas T; Galeano-Dalmau, Nuria N; O'Donovan, Maria M; Liu, Hongxiang H; Fitzgerald, Rebecca C RC
Pan-urologic cancer genomic subtypes that transcend tissue of origin.
Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Computational screening and molecular dynamic simulation of breast cancer associated deleterious non-synonymous single nucleotide polymorphisms in TP53 gene.
Plos One
Chitrala, Kumaraswamy Naidu KN; Yeguvapalli, Suneetha S
Publication Date: 2014
Variant appearance in text: TP53: A189V; rs121912665