TP53 c.544_545delinsGC ;(p.C182A)

Variant ID: 17-7578385-CA-GC

NM_000546.5(TP53):c.544_545delinsGC;(p.C182A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


The real-world performance of ThyroSeqV.2 to diagnose thyroid "neoplasm requiring surgery".

American Journal Of Cancer Research
Guan, Haixia H; Toraldo, Gianluca G; Godley, Frederick A FA; Rao, Sowmya R SR; Cerda, Sandra S; McAneny, David D; Doherty, Gerard G; Lee, Stephanie L SL
Publication Date: 2020

Variant appearance in text: TP53: c182A
PubMed Link: 33294271
Variant Present in the following documents:
  • Main text
View BVdb publication page



SAAMBE-3D: Predicting Effect of Mutations on Protein-Protein Interactions.

International Journal Of Molecular Sciences
Pahari, Swagata S; Li, Gen G; Murthy, Adithya Krishna AK; Liang, Siqi S; Fragoza, Robert R; Yu, Haiyuan H; Alexov, Emil E
Publication Date: 2020-04-07

Variant appearance in text: TP53: C182A
PubMed Link: 32272725
Variant Present in the following documents:
  • ijms-21-02563.pdf
View BVdb publication page



Patterns of germline and somatic mutations in 16 genes associated with mismatch repair function or containing tandem repeat sequences.

Cancer Medicine
Chang, Shih-Ching SC; Lan, Yuan-Tzu YT; Lin, Pei-Ching PC; Yang, Shung-Haur SH; Lin, Chien-Hsing CH; Liang, Wen-Yi WY; Chen, Wei-Shone WS; Jiang, Jeng-Kai JK; Lin, Jen-Kou JK
Publication Date: 2020-01

Variant appearance in text: TP53: c182A
PubMed Link: 31769227
Variant Present in the following documents:
  • CAM4-9-476-s002.pdf
View BVdb publication page



APR-246 reactivates mutant p53 by targeting cysteines 124 and 277.

Cell Death & Disease
Zhang, Qiang Q; Bykov, Vladimir J N VJN; Wiman, Klas G KG; Zawacka-Pankau, Joanna J
Publication Date: 2018-05-01

Variant appearance in text: p53: C182A
PubMed Link: 29670092
Variant Present in the following documents:
  • Main text
  • 41419_2018_Article_463.pdf
View BVdb publication page



Multiple conformations of full-length p53 detected with single-molecule fluorescence resonance energy transfer.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Huang, Fang F; Rajagopalan, Sridharan S; Settanni, Giovanni G; Marsh, Richard J RJ; Armoogum, Daven A DA; Nicolaou, Nick N; Bain, Angus J AJ; Lerner, Eitan E; Haas, Elisha E; Ying, Liming L; Fersht, Alan R AR
Publication Date: 2009-12-08

Variant appearance in text: p53: C182A
PubMed Link: 19933326
Variant Present in the following documents:
  • Main text
View BVdb publication page



Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress.

Biochemistry
Velu, Chinavenmeni S CS; Niture, Suryakant K SK; Doneanu, Catalin E CE; Pattabiraman, Nagarajan N; Srivenugopal, Kalkunte S KS
Publication Date: 2007-07-03

Variant appearance in text: p53: C182A
PubMed Link: 17555331
Variant Present in the following documents:
  • Main text
View BVdb publication page