Publications:

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: p53: 532C>T

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

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Integrated cohort of esophageal squamous cell cancer reveals genomic features underlying clinical characteristics.

Nature Communications

Li, Minghao M; Zhang, Zicheng Z; Wang, Qianrong Q; Yi, Yan Y; Li, Baosheng B

Publication Date: 2022-09-07

Variant appearance in text: TP53: H178Y

PubMed Link: 36071046

Variant Present in the following documents:

• 41467_2022_32962_MOESM15_ESM.xlsx, sheet 22

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Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications

Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A

Publication Date: 2022-07-13

Variant appearance in text: TP53: 532C>T; H178Y

PubMed Link: 35831314

Variant Present in the following documents:

• 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3

View BVdb publication page

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Characterization of disease-propagating stem cells responsible for myeloproliferative neoplasm-blast phase.

Jci Insight

Wang, Xiaoli X; Rampal, Raajit K RK; Hu, Cing Siang CS; Tripodi, Joseph J; Farnoud, Noushin N; Petersen, Bruce B; Rossi, Michael R MR; Patel, Minal M; McGovern, Erin E; Najfeld, Vesna V; Iancu-Rubin, Camelia C; Lu, Min M; Davis, Andrew A; Kremyanskaya, Marina M; Weinberg, Rona Singer RS; Mascarenhas, John J; Hoffman, Ronald R

Publication Date: 2022-04-22

Variant appearance in text: TP53: H178Y

PubMed Link: 35259128

Variant Present in the following documents:

• jciinsight-7-156534-s067.xlsx, sheet 1

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: TP53: H178Y

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: TP53: 532C>T; H178Y

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Coding and noncoding somatic mutations in candidate genes in basal cell carcinoma.

Scientific Reports

Maturo, Maria Giovanna MG; Rachakonda, Sivaramakrishna S; Heidenreich, Barbara B; Pellegrini, Cristina C; Srinivas, Nalini N; Requena, Celia C; Serra-Guillen, Carlos C; Llombart, Beatriz B; Sanmartin, Onofre O; Guillen, Carlos C; Di Nardo, Lucia L; Peris, Ketty K; Fargnoli, Maria Concetta MC; Nagore, Eduardo E; Kumar, Rajiv R

Publication Date: 2020-05-14

Variant appearance in text: TP53: 532C>T; H178Y

PubMed Link: 32409749

Variant Present in the following documents:

• 41598_2020_65057_MOESM1_ESM.pdf
• 41598_2020_65057_MOESM2_ESM.xlsx, sheet 3

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: TP53: H178Y

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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p53-responsive TLR8 SNP enhances human innate immune response to respiratory syncytial virus.

The Journal Of Clinical Investigation

Menendez, Daniel D; Snipe, Joyce J; Marzec, Jacqui J; Innes, Cynthia L CL; Polack, Fernando P FP; Caballero, Mauricio T MT; Schurman, Shepherd H SH; Kleeberger, Steven R SR; Resnick, Michael A MA

Publication Date: 2019-11-01

Variant appearance in text: p53: H178Y

PubMed Link: 31430261

Variant Present in the following documents:

• Main text

View BVdb publication page

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Decoding Somatic Driver Gene Mutations and Affected Signaling Pathways in Human Medulloblastoma Subgroups.

Journal Of Cancer

Robbins, Charles J CJ; Bou-Dargham, Mayassa J MJ; Sanchez, Kevin K; Rosen, Matthew C MC; Sang, Qing-Xiang Amy QA

Publication Date: 2018

Variant appearance in text: TP53: 532C>T

PubMed Link: 30588243

Variant Present in the following documents:

• jcav09p4596s2.xlsx, sheet 1

View BVdb publication page

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appreci8: a pipeline for precise variant calling integrating 8 tools.

Bioinformatics (Oxford, England)

Sandmann, Sarah S; Karimi, Mohsen M; de Graaf, Aniek O AO; Rohde, Christian C; Göllner, Stefanie S; Varghese, Julian J; Ernsting, Jan J; Walldin, Gunilla G; van der Reijden, Bert A BA; Müller-Tidow, Carsten C; Malcovati, Luca L; Hellström-Lindberg, Eva E; Jansen, Joop H JH; Dugas, Martin M

Publication Date: 2018-12-15

Variant appearance in text: TP53: 532C>T; His178Tyr

PubMed Link: 29945233

Variant Present in the following documents:

• bty518_supplementary_data_s2.xlsx, sheet 8

View BVdb publication page

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Germ-line and somatic EPHA2 coding variants in lens aging and cataract.

Plos One

Bennett, Thomas M TM; M'Hamdi, Oussama O; Hejtmancik, J Fielding JF; Shiels, Alan A

Publication Date: 2017

Variant appearance in text: TP53: H178Y

PubMed Link: 29267365

Variant Present in the following documents:

• pone.0189881.s008.xlsx, sheet 1
• pone.0189881.s007.xlsx, sheet 1

View BVdb publication page

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Targeted next-generation sequencing of cancer genes in poorly differentiated thyroid cancer.

Endocrine Connections

Gerber, Tiemo S TS; Schad, Arno A; Hartmann, Nils N; Springer, Erik E; Zechner, Ulrich U; Musholt, Thomas J TJ

Publication Date: 2018-01

Variant appearance in text: TP53: 532C>T

PubMed Link: 29133385

Variant Present in the following documents:

• ec-7-47-t001.pdf

View BVdb publication page

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In silico identification of rescue sites by double force scanning.

Bioinformatics (Oxford, England)

Tiberti, Matteo M; Pandini, Alessandro A; Fraternali, Franca F; Fornili, Arianna A

Publication Date: 2018-01-15

Variant appearance in text: p53: H178Y

PubMed Link: 28961796

Variant Present in the following documents:

• Main text
• btx515.pdf

View BVdb publication page

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p53, p63 and p73 in the wonderland of S. cerevisiae.

Oncotarget

Billant, Olivier O; Blondel, Marc M; Voisset, Cécile C

Publication Date: 2017-08-22

Variant appearance in text: p53: H178Y

PubMed Link: 28915717

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: TP53: 532C>T; H178Y

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Molecularly targeted therapies for p53-mutant cancers.

Cellular And Molecular Life Sciences : Cmls

Zhao, Dekuang D; Tahaney, William M WM; Mazumdar, Abhijit A; Savage, Michelle I MI; Brown, Powel H PH

Publication Date: 2017-11

Variant appearance in text: p53: H178Y

PubMed Link: 28643165

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Cytidine Deaminase APOBEC3 Family Is Subject to Transcriptional Regulation by p53.

Molecular Cancer Research : Mcr

Menendez, Daniel D; Nguyen, Thuy-Ai TA; Snipe, Joyce J; Resnick, Michael A MA

Publication Date: 2017-06

Variant appearance in text: p53: H178Y

PubMed Link: 28232385

Variant Present in the following documents:

• Main text

View BVdb publication page

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Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells.

Oncotarget

Menendez, Daniel D; Lowe, Julie M JM; Snipe, Joyce J; Resnick, Michael A MA

Publication Date: 2016-09-20

Variant appearance in text: p53: H178Y

PubMed Link: 27533082

Variant Present in the following documents:

• Main text
• oncotarget-07-61630.pdf
• oncotarget-07-61630-s002.xlsx, sheet 1
• oncotarget-07-61630-s001.pdf

View BVdb publication page

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VarDict: a novel and versatile variant caller for next-generation sequencing in cancer research.

Nucleic Acids Research

Lai, Zhongwu Z; Markovets, Aleksandra A; Ahdesmaki, Miika M; Chapman, Brad B; Hofmann, Oliver O; McEwen, Robert R; Johnson, Justin J; Dougherty, Brian B; Barrett, J Carl JC; Dry, Jonathan R JR

Publication Date: 2016-06-20

Variant appearance in text: TP53: 532C>T

PubMed Link: 27060149

Variant Present in the following documents:

• supp_gkw227_nar-03544-met-k-2015-File003.xls, sheet 2

View BVdb publication page

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Recurrent inactivating RASA2 mutations in melanoma.

Nature Genetics

Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y

Publication Date: 2015-12

Variant appearance in text: p53: H178Y

PubMed Link: 26502337

Variant Present in the following documents:

• NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 1

View BVdb publication page

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: TP53: H178Y

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 1

View BVdb publication page

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: H178Y

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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Correlation of transcription of MALAT-1, a novel noncoding RNA, with deregulated expression of tumor suppressor p53 in small DNA tumor virus models.

Journal Of Cancer Therapy

Jeffers, Liesl K LK; Duan, Kaiwen K; Ellies, Lesley G LG; Seaman, William T WT; Burger-Calderon, Raquel A RA; Diatchenko, Luda B LB; Webster-Cyriaque, Jennifer J

Publication Date: 2013-05

Variant appearance in text: p53: H178Y

PubMed Link: 24163781

Variant Present in the following documents:

• Main text

View BVdb publication page

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Structural studies of p53 inactivation by DNA-contact mutations and its rescue by suppressor mutations via alternative protein-DNA interactions.

Nucleic Acids Research

Eldar, Amir A; Rozenberg, Haim H; Diskin-Posner, Yael Y; Rohs, Remo R; Shakked, Zippora Z

Publication Date: 2013-10

Variant appearance in text: p53: H178Y

PubMed Link: 23863845

Variant Present in the following documents:

• Main text
• gkt630.pdf

View BVdb publication page

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High frequency of complex TP53 mutations in CNS metastases from breast cancer.

British Journal Of Cancer

Lo Nigro, C C; Vivenza, D D; Monteverde, M M; Lattanzio, L L; Gojis, O O; Garrone, O O; Comino, A A; Merlano, M M; Quinlan, P R PR; Syed, N N; Purdie, C A CA; Thompson, A A; Palmieri, C C; Crook, T T

Publication Date: 2012-01-17

Variant appearance in text: TP53: His178Tyr

PubMed Link: 22187033

Variant Present in the following documents:

• Main text
• bjc2011464a.pdf

View BVdb publication page

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: TP53: H178Y

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

View BVdb publication page

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p53 binds to and is required for the repression of Arf tumor suppressor by HDAC and polycomb.

Cancer Research

Zeng, Yaxue Y; Kotake, Yojiro Y; Pei, Xin-Hai XH; Smith, Matthew D MD; Xiong, Yue Y

Publication Date: 2011-04-01

Variant appearance in text: p53: H178Y

PubMed Link: 21447739

Variant Present in the following documents:

• Main text

View BVdb publication page

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The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes.

Molecular And Cellular Biology

Menendez, Daniel D; Inga, Alberto A; Resnick, Michael A MA

Publication Date: 2006-03

Variant appearance in text: p53: H178Y

PubMed Link: 16508005

Variant Present in the following documents:

• Main text

View BVdb publication page

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