Publications:

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Mutant p53 in cancer: from molecular mechanism to therapeutic modulation.

Cell Death & Disease

Chen, Xiaohua X; Zhang, Taotao T; Su, Wei W; Dou, Zhihui Z; Zhao, Dapeng D; Jin, Xiaodong X; Lei, Huiwen H; Wang, Jing J; Xie, Xiaodong X; Cheng, Bo B; Li, Qiang Q; Zhang, Hong H; Di, Cuixia C

Publication Date: 2022-11-18

Variant appearance in text: p53: R175P

PubMed Link: 36400749

Variant Present in the following documents:

• Main text
• 41419_2022_Article_5408.pdf

View BVdb publication page

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: p53: 524G>C

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

View BVdb publication page

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When PIP2 Meets p53: Nuclear Phosphoinositide Signaling in the DNA Damage Response.

Frontiers In Cell And Developmental Biology

Wang, Yu-Hsiu YH; Sheetz, Michael P MP

Publication Date: 2022

Variant appearance in text: p53: R175P

PubMed Link: 35646908

Variant Present in the following documents:

• Main text
• fcell-10-903994.pdf

View BVdb publication page

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Prognostic Value of Postoperative Circulating Tumor DNA in Patients With Early- and Intermediate-Stage Hepatocellular Carcinoma.

Frontiers In Oncology

Ye, Ke K; Fan, Qinqiao Q; Yuan, Mingming M; Wang, Dong D; Xiao, Liang L; Long, Guo G; Chen, Rongrong R; Fang, Tongdi T; Li, Zengbo Z; Zhou, Ledu L

Publication Date: 2022

Variant appearance in text: TP53: 524G>C; R175P

PubMed Link: 35311090

Variant Present in the following documents:

• Table_1.xlsx, sheet 3

View BVdb publication page

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Characterization of disease-propagating stem cells responsible for myeloproliferative neoplasm-blast phase.

Jci Insight

Wang, Xiaoli X; Rampal, Raajit K RK; Hu, Cing Siang CS; Tripodi, Joseph J; Farnoud, Noushin N; Petersen, Bruce B; Rossi, Michael R MR; Patel, Minal M; McGovern, Erin E; Najfeld, Vesna V; Iancu-Rubin, Camelia C; Lu, Min M; Davis, Andrew A; Kremyanskaya, Marina M; Weinberg, Rona Singer RS; Mascarenhas, John J; Hoffman, Ronald R

Publication Date: 2022-04-22

Variant appearance in text: TP53: R175P

PubMed Link: 35259128

Variant Present in the following documents:

• jciinsight-7-156534-s067.xlsx, sheet 1

View BVdb publication page

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Rapid recruitment of p53 to DNA damage sites directs DNA repair choice and integrity.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Wang, Yu-Hsiu YH; Ho, Teresa L F TLF; Hariharan, Anushya A; Goh, Hui Chin HC; Wong, Yao Liang YL; Verkaik, Nicole S NS; Lee, May Yin MY; Tam, Wai Leong WL; van Gent, Dik C DC; Venkitaraman, Ashok R AR; Sheetz, Michael P MP; Lane, David P DP

Publication Date: 2022-03-08

Variant appearance in text: p53: R175P

PubMed Link: 35235448

Variant Present in the following documents:

• pnas.202113233.pdf

View BVdb publication page

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p53 partial loss-of-function mutations sensitize to chemotherapy.

Oncogene

Klimovich, Boris B; Merle, Nastasja N; Neumann, Michelle M; Elmshäuser, Sabrina S; Nist, Andrea A; Mernberger, Marco M; Kazdal, Daniel D; Stenzinger, Albrecht A; Timofeev, Oleg O; Stiewe, Thorsten T

Publication Date: 2022-02

Variant appearance in text: p53: R175P

PubMed Link: 34907344

Variant Present in the following documents:

• Main text
• 41388_2021_Article_2141.pdf

View BVdb publication page

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TP53 Mutation Is a Prognostic Factor in Lower Grade Glioma and May Influence Chemotherapy Efficacy.

Cancers

Noor, Humaira H; Briggs, Nancy E NE; McDonald, Kerrie L KL; Holst, Jeff J; Vittorio, Orazio O

Publication Date: 2021-10-26

Variant appearance in text: TP53: 524G>C

PubMed Link: 34771529

Variant Present in the following documents:

• Main text
• cancers-13-05362.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: TP53: R175P

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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TP53 in Biology and Treatment of Osteosarcoma.

Cancers

Synoradzki, Kamil Jozef KJ; Bartnik, Ewa E; Czarnecka, Anna M AM; Fiedorowicz, Michał M; Firlej, Wiktoria W; Brodziak, Anna A; Stasinska, Agnieszka A; Rutkowski, Piotr P; Grieb, Paweł P

Publication Date: 2021-08-25

Variant appearance in text: p53: R175P

PubMed Link: 34503094

Variant Present in the following documents:

• Main text
• cancers-13-04284.pdf

View BVdb publication page

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Targeted Sequencing of Taiwanese Breast Cancer with Risk Stratification by the Concurrent Genes Signature: A Feasibility Study.

Journal Of Personalized Medicine

Huang, Ching-Shui CS; Liu, Chih-Yi CY; Lu, Tzu-Pin TP; Huang, Chi-Jung CJ; Chiu, Jen-Hwey JH; Tseng, Ling-Ming LM; Huang, Chi-Cheng CC

Publication Date: 2021-06-28

Variant appearance in text: TP53: R175P

PubMed Link: 34203389

Variant Present in the following documents:

• Main text
• jpm-11-00613.pdf

View BVdb publication page

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Rely on Each Other: DNA Binding Cooperativity Shapes p53 Functions in Tumor Suppression and Cancer Therapy.

Cancers

Timofeev, Oleg O; Stiewe, Thorsten T

Publication Date: 2021-05-17

Variant appearance in text: p53: R175P

PubMed Link: 34067731

Variant Present in the following documents:

• Main text
• cancers-13-02422.pdf

View BVdb publication page

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Identification of a targetable KRAS-mutant epithelial population in non-small cell lung cancer.

Communications Biology

Maroni, Giorgia G; Bassal, Mahmoud A MA; Krishnan, Indira I; Fhu, Chee Wai CW; Savova, Virginia V; Zilionis, Rapolas R; Maymi, Valerie A VA; Pandell, Nicole N; Csizmadia, Eva E; Zhang, Junyan J; Storti, Barbara B; Castaño, Julio J; Panella, Riccardo R; Li, Jia J; Gustafson, Corinne E CE; Fox, Sam S; Levy, Rachel D RD; Meyerovitz, Claire V CV; Tramontozzi, Peter J PJ; Vermilya, Kimberly K; De Rienzo, Assunta A; Crucitta, Stefania S; Bassères, Daniela S DS; Weetall, Marla M; Branstrom, Art A; Giorgetti, Alessandra A; Ciampi, Raffaele R; Del Re, Marzia M; Danesi, Romano R; Bizzarri, Ranieri R; Yang, Henry H; Kocher, Olivier O; Klein, Allon M AM; Welner, Robert S RS; Bueno, Raphael R; Magli, Maria Cristina MC; Clohessy, John G JG; Ali, Azhar A; Tenen, Daniel G DG; Levantini, Elena E

Publication Date: 2021-04-14

Variant appearance in text: TP53: Arg175Pro

PubMed Link: 33854168

Variant Present in the following documents:

• 42003_2021_1897_MOESM4_ESM.xlsx, sheet 2

View BVdb publication page

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: TP53: 524G>C; R175P

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Regulation of p53 by E3s.

Cancers

Pan, Mengwu M; Blattner, Christine C

Publication Date: 2021-02-11

Variant appearance in text: p53: R175P

PubMed Link: 33670160

Variant Present in the following documents:

• Main text

View BVdb publication page

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Assessment of Clinical Benefit of Integrative Genomic Profiling in Advanced Solid Tumors.

Jama Oncology

Cobain, Erin F EF; Wu, Yi-Mi YM; Vats, Pankaj P; Chugh, Rashmi R; Worden, Francis F; Smith, David C DC; Schuetze, Scott M SM; Zalupski, Mark M MM; Sahai, Vaibhav V; Alva, Ajjai A; Schott, Anne F AF; Caram, Megan E V MEV; Hayes, Daniel F DF; Stoffel, Elena M EM; Jacobs, Michelle F MF; Kumar-Sinha, Chandan C; Cao, Xuhong X; Wang, Rui R; Lucas, David D; Ning, Yu Y; Rabban, Erica E; Bell, Janice J; Camelo-Piragua, Sandra S; Udager, Aaron M AM; Cieslik, Marcin M; Lonigro, Robert J RJ; Kunju, Lakshmi P LP; Robinson, Dan R DR; Talpaz, Moshe M; Chinnaiyan, Arul M AM

Publication Date: 2021-04-01

Variant appearance in text: TP53: R175P

PubMed Link: 33630025

Variant Present in the following documents:

• jamaoncol-e207987-s004.xlsx, sheet 2

View BVdb publication page

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Mutant p53 as a Regulator and Target of Autophagy.

Frontiers In Oncology

Shi, Yong Y; Norberg, Erik E; Vakifahmetoglu-Norberg, Helin H

Publication Date: 2020

Variant appearance in text: p53: R175P

PubMed Link: 33614491

Variant Present in the following documents:

• Main text

View BVdb publication page

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Utility of a custom designed next generation DNA sequencing gene panel to molecularly classify endometrial cancers according to The Cancer Genome Atlas subgroups.

Bmc Medical Genomics

Miller, Eirwen M EM; Patterson, Nicole E NE; Gressel, Gregory M GM; Karabakhtsian, Rouzan G RG; Bejerano-Sagie, Michal M; Ravi, Nivedita N; Maslov, Alexander A; Quispe-Tintaya, Wilber W; Wang, Tao T; Lin, Juan J; Smith, Harriet O HO; Goldberg, Gary L GL; Kuo, Dennis Y S DYS; Montagna, Cristina C

Publication Date: 2020-11-30

Variant appearance in text: TP53: R175P

PubMed Link: 33256706

Variant Present in the following documents:

• 12920_2020_824_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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Heterogeneity of TP53 Mutations and P53 Protein Residual Function in Cancer: Does It Matter?

Frontiers In Oncology

Monti, Paola P; Menichini, Paola P; Speciale, Andrea A; Cutrona, Giovanna G; Fais, Franco F; Taiana, Elisa E; Neri, Antonino A; Bomben, Riccardo R; Gentile, Massimo M; Gattei, Valter V; Ferrarini, Manlio M; Morabito, Fortunato F; Fronza, Gilberto G

Publication Date: 2020

Variant appearance in text: TP53: R175P

PubMed Link: 33194757

Variant Present in the following documents:

• Main text
• fonc-10-593383.pdf

View BVdb publication page

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Spectrum of TP53 Mutations in BRCA1/2 Associated High-Grade Serous Ovarian Cancer.

Frontiers In Oncology

Boyarskikh, Ulyana A UA; Gulyaeva, L F LF; Avdalyan, A M AM; Kechin, A A AA; Khrapov, E A EA; Lazareva, D G DG; Kushlinskii, N E NE; Melkonyan, A A; Arakelyan, A A; Filipenko, Maxim Leonidovich ML

Publication Date: 2020

Variant appearance in text: p53: R175P

PubMed Link: 32766142

Variant Present in the following documents:

• Main text
• fonc-10-01103.pdf

View BVdb publication page

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Defining relative mutational difficulty to understand cancer formation.

Cell Discovery

Shan, Lin L; Yu, Jiao J; He, Zhengjin Z; Chen, Shishuang S; Liu, Mingxian M; Ding, Hongyu H; Xu, Liang L; Zhao, Jie J; Yang, Ailing A; Jiang, Hai H

Publication Date: 2020

Variant appearance in text: p53: R175P

PubMed Link: 32704382

Variant Present in the following documents:

• 41421_2020_177_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Sphingolipids and the link between alcohol and cancer.

Chemico-Biological Interactions

Barron, Keri A KA; Jeffries, Kristen A KA; Krupenko, Natalia I NI

Publication Date: 2020-05-01

Variant appearance in text: p53: R175P

PubMed Link: 32171848

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: TP53: R175P

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer.

Nature Communications

Leal, Alessandro A; van Grieken, Nicole C T NCT; Palsgrove, Doreen N DN; Phallen, Jillian J; Medina, Jamie E JE; Hruban, Carolyn C; Broeckaert, Mark A M MAM; Anagnostou, Valsamo V; Adleff, Vilmos V; Bruhm, Daniel C DC; Canzoniero, Jenna V JV; Fiksel, Jacob J; Nordsmark, Marianne M; Warmerdam, Fabienne A R M FARM; Verheul, Henk M W HMW; van Spronsen, Dick Johan DJ; Beerepoot, Laurens V LV; Geenen, Maud M MM; Portielje, Johanneke E A JEA; Jansen, Edwin P M EPM; van Sandick, Johanna J; Meershoek-Klein Kranenbarg, Elma E; van Laarhoven, Hanneke W M HWM; van der Peet, Donald L DL; van de Velde, Cornelis J H CJH; Verheij, Marcel M; Fijneman, Remond R; Scharpf, Robert B RB; Meijer, Gerrit A GA; Cats, Annemieke A; Velculescu, Victor E VE

Publication Date: 2020-01-27

Variant appearance in text: TP53: R175P

PubMed Link: 31988276

Variant Present in the following documents:

• 41467_2020_14310_MOESM11_ESM.xlsx, sheet 1
• 41467_2020_14310_MOESM8_ESM.xlsx, sheet 1
• 41467_2020_14310_MOESM6_ESM.xlsx, sheet 8
• 41467_2020_14310_MOESM6_ESM.xlsx, sheet 9
• 41467_2020_14310_MOESM10_ESM.xlsx, sheet 1
• 41467_2020_14310_MOESM6_ESM.xlsx, sheet 6

View BVdb publication page

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Sox2+ cells in Sonic Hedgehog-subtype medulloblastoma resist p53-mediated cell-cycle arrest response and drive therapy-induced recurrence.

Neuro-Oncology Advances

Treisman, Daniel M DM; Li, Yinghua Y; Pierce, Brianna R BR; Li, Chaoyang C; Chervenak, Andrew P AP; Tomasek, Gerald J GJ; Lozano, Guillermina G; Zheng, Xiaoyan X; Kool, Marcel M; Zhu, Yuan Y

Publication Date: 2019

Variant appearance in text: TP53: R175P

PubMed Link: 31763624

Variant Present in the following documents:

• Main text

View BVdb publication page

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Inactivation of Mdm2 restores apoptosis proficiency of cooperativity mutant p53 in vivo.

Cell Cycle (Georgetown, Tex.)

Klimovich, Boris B; Stiewe, Thorsten T; Timofeev, Oleg O

Publication Date: 2020-01

Variant appearance in text: p53: R175P

PubMed Link: 31749402

Variant Present in the following documents:

• Main text

View BVdb publication page

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Rapid generation and selection of Cas9-engineering TRP53 R172P mice that do not have off-target effects.

Bmc Biotechnology

Zheng, Guoxing G; Zhu, Qingqing Q; Dong, Junchao J; Lin, Xin X; Zhu, Chengming C

Publication Date: 2019-11-08

Variant appearance in text: TP53: Arg175Pro

PubMed Link: 31703569

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pan-cancer whole-genome analyses of metastatic solid tumours.

Nature

Priestley, Peter P; Baber, Jonathan J; Lolkema, Martijn P MP; Steeghs, Neeltje N; de Bruijn, Ewart E; Shale, Charles C; Duyvesteyn, Korneel K; Haidari, Susan S; van Hoeck, Arne A; Onstenk, Wendy W; Roepman, Paul P; Voda, Mircea M; Bloemendal, Haiko J HJ; Tjan-Heijnen, Vivianne C G VCG; van Herpen, Carla M L CML; Labots, Mariette M; Witteveen, Petronella O PO; Smit, Egbert F EF; Sleijfer, Stefan S; Voest, Emile E EE; Cuppen, Edwin E

Publication Date: 2019-11

Variant appearance in text: TP53: Arg175Pro

PubMed Link: 31645765

Variant Present in the following documents:

• 41586_2019_1689_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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Residual apoptotic activity of a tumorigenic p53 mutant improves cancer therapy responses.

The Embo Journal

Timofeev, Oleg O; Klimovich, Boris B; Schneikert, Jean J; Wanzel, Michael M; Pavlakis, Evangelos E; Noll, Julia J; Mutlu, Samet S; Elmshäuser, Sabrina S; Nist, Andrea A; Mernberger, Marco M; Lamp, Boris B; Wenig, Ulrich U; Brobeil, Alexander A; Gattenlöhner, Stefan S; Köhler, Kernt K; Stiewe, Thorsten T

Publication Date: 2019-10-15

Variant appearance in text: p53: R175P

PubMed Link: 31483066

Variant Present in the following documents:

• Main text
• EMBJ-38-e102096.pdf

View BVdb publication page

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Molecular and in-silico analysis of single nucleotide polymorphism targeting human TP53 gene exon 5-8 in Sudanese esophageal cancer patients.

F1000Research

Elfaki, Rihab M RM; Abdelaziz, Mohammed S MS; Altayb, Hisham N HN; Munsoor, Munsoor M MM; Gameel, Ahmed A AA

Publication Date: 2018

Variant appearance in text: TP53: R175P

PubMed Link: 31316750

Variant Present in the following documents:

• Main text
• f1000research-7-16944.pdf

View BVdb publication page

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: TP53: R175P

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

View BVdb publication page

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Integrative molecular profiling identifies a novel cluster of estrogen receptor-positive breast cancer in very young women.

Cancer Science

Park, Charny C; Yoon, Kyong-Ah KA; Kim, Jihyun J; Park, In Hae IH; Park, Soo Jin SJ; Kim, Min Kyeong MK; Jang, Wooyeong W; Cho, Soo Young SY; Park, Boyoung B; Kong, Sun-Young SY; Lee, Eun Sook ES

Publication Date: 2019-05

Variant appearance in text: p53: R175P

PubMed Link: 30811755

Variant Present in the following documents:

• CAS-110-1760-s002.xlsx, sheet 2

View BVdb publication page

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Functional relationship between p53 and RUNX proteins.

Journal Of Molecular Cell Biology

Bae, Suk-Chul SC; Kolinjivadi, Arun Mouli AM; Ito, Yoshiaki Y

Publication Date: 2019-03-01

Variant appearance in text: p53: R175P

PubMed Link: 30535344

Variant Present in the following documents:

• Main text
• mjy076.pdf

View BVdb publication page

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HPV positive, wild type TP53, and p16 overexpression correlate with the absence of residual tumors after chemoradiotherapy in anal squamous cell carcinoma.

Bmc Gastroenterology

Soares, Paulo C PC; Abdelhay, Eliana S ES; Thuler, Luiz Claudio S LCS; Soares, Bruno Moreira BM; Demachki, Samia S; Ferro, Gessica Valéria Rocha GVR; Assumpção, Paulo P PP; Lamarão, Leticia Martins LM; Ribeiro Pinto, Luis Felipe LF; Burbano, Rommel Mario Rodríguez RMR

Publication Date: 2018-02-21

Variant appearance in text: TP53: R175P

PubMed Link: 29466950

Variant Present in the following documents:

• Main text

View BVdb publication page

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p53 orchestrates DNA replication restart homeostasis by suppressing mutagenic RAD52 and POLθ pathways.

Elife

Roy, Sunetra S; Tomaszowski, Karl-Heinz KH; Luzwick, Jessica W JW; Park, Soyoung S; Li, Jun J; Murphy, Maureen M; Schlacher, Katharina K

Publication Date: 2018-01-15

Variant appearance in text: p53: R175P

PubMed Link: 29334356

Variant Present in the following documents:

• Main text
• elife-31723.pdf

View BVdb publication page

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Control of Nucleotide Metabolism Enables Mutant p53's Oncogenic Gain-of-Function Activity.

International Journal Of Molecular Sciences

Schmidt, Valentina V; Nagar, Rachana R; Martinez, Luis A LA

Publication Date: 2017-12-19

Variant appearance in text: p53: R175P

PubMed Link: 29257071

Variant Present in the following documents:

• Main text
• ijms-18-02759.pdf

View BVdb publication page

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Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas.

Acta Neuropathologica Communications

Salloum, Ralph R; McConechy, Melissa K MK; Mikael, Leonie G LG; Fuller, Christine C; Drissi, Rachid R; DeWire, Mariko M; Nikbakht, Hamid H; De Jay, Nicolas N; Yang, Xiaodan X; Boue, Daniel D; Chow, Lionel M L LML; Finlay, Jonathan L JL; Gayden, Tenzin T; Karamchandani, Jason J; Hummel, Trent R TR; Olshefski, Randal R; Osorio, Diana S DS; Stevenson, Charles C; Kleinman, Claudia L CL; Majewski, Jacek J; Fouladi, Maryam M; Jabado, Nada N

Publication Date: 2017-10-30

Variant appearance in text: p53: R175P

PubMed Link: 29084603

Variant Present in the following documents:

• 40478_2017_479_MOESM2_ESM.xlsx, sheet 10

View BVdb publication page

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Cancer gene profiling in non-small cell lung cancers reveals activating mutations in JAK2 and JAK3 with therapeutic implications.

Genome Medicine

Li, Shuyu D SD; Ma, Meng M; Li, Hui H; Waluszko, Aneta A; Sidorenko, Tatyana T; Schadt, Eric E EE; Zhang, David Y DY; Chen, Rong R; Ye, Fei F

Publication Date: 2017-10-30

Variant appearance in text: TP53: 524G>C; R175P

PubMed Link: 29082853

Variant Present in the following documents:

• 13073_2017_478_MOESM1_ESM.xlsx, sheet 2

View BVdb publication page

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Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia.

Leukemia

Nadeu, F F; Clot, G G; Delgado, J J; Martín-García, D D; Baumann, T T; Salaverria, I I; Beà, S S; Pinyol, M M; Jares, P P; Navarro, A A; Suárez-Cisneros, H H; Aymerich, M M; Rozman, M M; Villamor, N N; Colomer, D D; González, M M; Alcoceba, M M; Terol, M J MJ; Navarro, B B; Colado, E E; Payer, Á R ÁR; Puente, X S XS; López-Otín, C C; López-Guillermo, A A; Enjuanes, A A; Campo, E E

Publication Date: 2018-03

Variant appearance in text: TP53: R175P

PubMed Link: 28924241

Variant Present in the following documents:

• leu2017291x4.xlsx, sheet 1

View BVdb publication page

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p53, p63 and p73 in the wonderland of S. cerevisiae.

Oncotarget

Billant, Olivier O; Blondel, Marc M; Voisset, Cécile C

Publication Date: 2017-08-22

Variant appearance in text: p53: R175P

PubMed Link: 28915717

Variant Present in the following documents:

• Main text

View BVdb publication page

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Putting p53 in Context.

Cell

Kastenhuber, Edward R ER; Lowe, Scott W SW

Publication Date: 2017-09-07

Variant appearance in text: p53: R175P

PubMed Link: 28886379

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications

Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ

Publication Date: 2017-08-04

Variant appearance in text: TP53: 524G>C; R175P

PubMed Link: 28775315

Variant Present in the following documents:

• 41467_2017_289_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Inherited TP53 Mutations and the Li-Fraumeni Syndrome.

Cold Spring Harbor Perspectives In Medicine

Guha, Tanya T; Malkin, David D

Publication Date: 2017-04-03

Variant appearance in text: TP53: R175P

PubMed Link: 28270529

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Role of Aneuploidy in Cancer Evolution.

Cold Spring Harbor Perspectives In Medicine

Sansregret, Laurent L; Swanton, Charles C

Publication Date: 2017-01-03

Variant appearance in text: p53: R175P

PubMed Link: 28049655

Variant Present in the following documents:

• Main text

View BVdb publication page

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: R175P

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

View BVdb publication page

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A new function for p53 tetramerization domain in cell fate control.

Cell Cycle (Georgetown, Tex.)

Zhang, Jin J; Lucchesi, Christopher C; Chen, Xinbin X

Publication Date: 2016-11

Variant appearance in text: p53: R175P

PubMed Link: 27355441

Variant Present in the following documents:

• Main text

View BVdb publication page

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Lysines in the tetramerization domain of p53 selectively modulate G1 arrest.

Cell Cycle (Georgetown, Tex.)

Beckerman, Rachel R; Yoh, Kathryn K; Mattia-Sansobrino, Melissa M; Zupnick, Andrew A; Laptenko, Oleg O; Karni-Schmidt, Orit O; Ahn, Jinwoo J; Byeon, In-Ja IJ; Keezer, Susan S; Prives, Carol C

Publication Date: 2016-06-02

Variant appearance in text: p53: R175P

PubMed Link: 27210019

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Cerebellum Development and Tumorigenesis: A p53-Centric Perspective.

Trends In Molecular Medicine

Barthelery, Nicolas J NJ; Manfredi, James J JJ

Publication Date: 2016-05

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PubMed Link: 27085812

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The Cell-Cycle Arrest and Apoptotic Functions of p53 in Tumor Initiation and Progression.

Cold Spring Harbor Perspectives In Medicine

Chen, Jiandong J

Publication Date: 2016-03-01

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PubMed Link: 26931810

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Specific TP53 Mutants Overrepresented in Ovarian Cancer Impact CNV, TP53 Activity, Responses to Nutlin-3a, and Cell Survival.

Neoplasia (New York, N.Y.)

Mullany, Lisa K LK; Wong, Kwong-Kwok KK; Marciano, David C DC; Katsonis, Panagiotis P; King-Crane, Erin R ER; Ren, Yi Athena YA; Lichtarge, Olivier O; Richards, JoAnne S JS

Publication Date: 2015-10

Variant appearance in text: p53: R175P

PubMed Link: 26585234

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: TP53: R175P

PubMed Link: 26206375

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• 12859_2015_673_MOESM1_ESM.xls, sheet 1

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TP53: an oncogene in disguise.

Cell Death And Differentiation

Soussi, T T; Wiman, K G KG

Publication Date: 2015-08

Variant appearance in text: p53: R175P

PubMed Link: 26024390

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• cdd201553a.pdf

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Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets.

Nature Communications

Witkiewicz, Agnieszka K AK; McMillan, Elizabeth A EA; Balaji, Uthra U; Baek, GuemHee G; Lin, Wan-Chi WC; Mansour, John J; Mollaee, Mehri M; Wagner, Kay-Uwe KU; Koduru, Prasad P; Yopp, Adam A; Choti, Michael A MA; Yeo, Charles J CJ; McCue, Peter P; White, Michael A MA; Knudsen, Erik S ES

Publication Date: 2015-04-09

Variant appearance in text: p53: R175P

PubMed Link: 25855536

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• ncomms7744-s2.xlsx, sheet 1

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: R175P

PubMed Link: 25348012

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• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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