TP53 c.486C>T ;(p.I162=)

Variant ID: 17-7578444-G-A

NM_000546.5(TP53):c.486C>T;(p.I162=)

This variant was identified in 11 publications

View GRCh38 version.




Publications:


Evaluating the prognostic significance of p53 and TP53 mutations in HPV-negative hypopharyngeal carcinoma patients: a 5-year follow-up retrospective study.

Bmc Cancer
Huang, Qiang Q; Li, Feiran F; Ji, Mengyou M; Lin, Lan L; Hu, Chunyan C
Publication Date: 2023-04-06

Variant appearance in text: TP53: I162I
PubMed Link: 37024846
Variant Present in the following documents:
  • Main text
  • 12885_2023_Article_10775.pdf
View BVdb publication page



TP53 Targeted Deep Sequencing of Cell-Free DNA in Esophageal Squamous Cell Carcinoma Using Low-Quality Serum: Concordance with Tumor Mutation.

International Journal Of Molecular Sciences
Nasrollahzadeh, Dariush D; Roshandel, Gholamreza G; Delhomme, Tiffany Myriam TM; Avogbe, Patrice Hodonou PH; Foll, Matthieu M; Saidi, Farrokh F; Poustchi, Hossein H; Sotoudeh, Masoud M; Malekzadeh, Reza R; Brennan, Paul P; Mckay, James J; Hainaut, Pierre P; Abedi-Ardekani, Behnoush B
Publication Date: 2021-05-26

Variant appearance in text: TP53: I162I
PubMed Link: 34073316
Variant Present in the following documents:
  • Main text
View BVdb publication page



Synonymous variants that disrupt messenger RNA structure are significantly constrained in the human population.

Gigascience
Gaither, Jeffrey B S JBS; Lammi, Grant E GE; Li, James L JL; Gordon, David M DM; Kuck, Harkness C HC; Kelly, Benjamin J BJ; Fitch, James R JR; White, Peter P
Publication Date: 2021-04-05

Variant appearance in text: TP53: 486C>T
PubMed Link: 33822938
Variant Present in the following documents:
  • giab023_giga-d-20-00178_revision_1.pdf
  • giab023_giga-d-20-00178_revision_2.pdf
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: TP53: 486C>T; I162I
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.

Nature Communications
Su, Dan D; Zhang, Dadong D; Jin, Jiaoyue J; Ying, Lisha L; Han, Miao M; Chen, Kaiyan K; Li, Bin B; Wu, Junzhou J; Xie, Zhenghua Z; Zhang, Fanrong F; Lin, Yihui Y; Cheng, Guoping G; Li, Jing-Yu JY; Huang, Minran M; Wang, Jinchao J; Wang, Kailai K; Zhang, Jianjun J; Li, Fugen F; Xiong, Lei L; Futreal, Andrew A; Mao, Weimin W
Publication Date: 2019-11-07

Variant appearance in text: TP53: 486C>T
PubMed Link: 31700061
Variant Present in the following documents:
  • 41467_2019_12846_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Genome-wide DNA methylation profiling shows molecular heterogeneity of anaplastic pleomorphic xanthoastrocytoma.

Cancer Science
Nakamura, Taishi T; Fukuoka, Kohei K; Nakano, Yoshiko Y; Yamasaki, Kai K; Matsushita, Yuko Y; Yamashita, Satoshi S; Ikeda, Junji J; Udaka, Naoko N; Tanoshima, Reo R; Shiba, Norio N; Tateishi, Kensuke K; Yamanaka, Shoji S; Yamamoto, Tetsuya T; Hirato, Junko J; Ichimura, Koichi K
Publication Date: 2019-02

Variant appearance in text: TP53: 486C>T
PubMed Link: 30609203
Variant Present in the following documents:
  • CAS-110-828-s011.xlsx, sheet 1
View BVdb publication page



Mutation of TP53, translocation analysis and immunohistochemical expression of MYC, BCL-2 and BCL-6 in patients with DLBCL treated with R-CHOP.

Scientific Reports
Peroja, Pekka P; Pedersen, Mette M; Mantere, Tuomo T; Nørgaard, Peter P; Peltonen, Jenni J; Haapasaari, Kirsi-Maria KM; Böhm, Jan J; Jantunen, Esa E; Turpeenniemi-Hujanen, Taina T; Rapakko, Katrin K; Karihtala, Peeter P; Soini, Ylermi Y; Vasala, Kaija K; Kuittinen, Outi O
Publication Date: 2018-10-04

Variant appearance in text: TP53: 486C>T; I162I
PubMed Link: 30287880
Variant Present in the following documents:
  • Main text
  • 41598_2018_Article_33230.pdf
View BVdb publication page



Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model.

Oncotarget
Zhang, Zhuo Z; Shiratsuchi, Hiroe H; Lin, Jules J; Chen, Guoan G; Reddy, Rishindra M RM; Azizi, Ebrahim E; Fouladdel, Shamileh S; Chang, Andrew C AC; Lin, Lin L; Jiang, Hui H; Waghray, Meghna M; Luker, Gary G; Simeone, Diane M DM; Wicha, Max S MS; Beer, David G DG; Ramnath, Nithya N; Nagrath, Sunitha S
Publication Date: 2014-12-15

Variant appearance in text: TP53: I162I
PubMed Link: 25474037
Variant Present in the following documents:
  • oncotarget-05-12383-s001.pdf
View BVdb publication page



TP53 and PIK3CA gene mutations in adenocarcinoma, squamous cell carcinoma and high-grade intraepithelial neoplasia of the cervix.

Journal Of Translational Medicine
Tornesello, Maria Lina ML; Annunziata, Clorinda C; Buonaguro, Luigi L; Losito, Simona S; Greggi, Stefano S; Buonaguro, Franco M FM
Publication Date: 2014-09-16

Variant appearance in text: TP53: I162I
PubMed Link: 25220666
Variant Present in the following documents:
  • Main text
  • 12967_2014_Article_255.pdf
View BVdb publication page



TP53 genetic alterations in Arab breast cancer patients: Novel mutations, pattern and distribution.

Oncology Letters
Al-Qasem, Abeer J AJ; Toulimat, Mohamed M; Eldali, Abdelmoneim M AM; Tulbah, Asma A; Al-Yousef, Nujoud N; Al-Daihan, Sooad K SK; Al-Tassan, Nada N; Al-Tweigeri, Taher T; Aboussekhra, Abdelilah A
Publication Date: 2011-03

Variant appearance in text: TP53: I162I
PubMed Link: 22866089
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evidence that p53-mediated cell-cycle-arrest inhibits chemotherapeutic treatment of ovarian carcinomas.

Plos One
Moreno, Carlos S CS; Matyunina, Lilya L; Dickerson, Erin B EB; Schubert, Nina N; Bowen, Nathan J NJ; Logani, Sanjay S; Benigno, Benedict B BB; McDonald, John F JF
Publication Date: 2007-05-16

Variant appearance in text: p53: I162I
PubMed Link: 17505532
Variant Present in the following documents:
  • Main text
  • pone.0000441.pdf
View BVdb publication page