TP53 c.481_482delinsTT ;(p.A161F)

Variant ID: 17-7578448-GC-AA

NM_000546.5(TP53):c.481_482delinsTT;(p.A161F)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience
Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X
Publication Date: 2022-09-16

Variant appearance in text: p53: A161F
PubMed Link: 36117989
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page



Outcomes in oncogenic-addicted advanced NSCLC patients with actionable mutations identified by liquid biopsy genomic profiling using a tagged amplicon-based NGS assay.

Plos One
Remon, Jordi J; Swalduz, Aurelie A; Planchard, David D; Ortiz-Cuaran, Sandra S; Mezquita, Laura L; Lacroix, Ludovic L; Jovelet, Cecile C; Rouleau, Etienne E; Leonce, Camille C; De Kievit, Frank F; Morris, Clive C; Jones, Greg G; Mercier, Kelly K; Howarth, Karen K; Green, Emma E; Pérol, Maurice M; Saintigny, Pierre P; Besse, Benjamin B
Publication Date: 2020

Variant appearance in text: TP53: A161F
PubMed Link: 32525942
Variant Present in the following documents:
  • pone.0234302.s001.xlsx, sheet 1
View BVdb publication page



Chemopreventive targeted treatment of head and neck precancer by Wee1 inhibition.

Scientific Reports
van Harten, Anne M AM; de Boer, D Vicky DV; Martens-de Kemp, Sanne R SR; Buijze, Marijke M; Ganzevles, Sonja H SH; Hunter, Keith D KD; Leemans, C René CR; van Beusechem, Victor W VW; Wolthuis, Rob M F RMF; de Menezes, Renée X RX; Brakenhoff, Ruud H RH
Publication Date: 2020-02-11

Variant appearance in text: TP53: A161F
PubMed Link: 32047167
Variant Present in the following documents:
  • 41598_2020_58509_MOESM1_ESM.pdf
View BVdb publication page



GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics
Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J
Publication Date: 2015-07-25

Variant appearance in text: TP53: A161F
PubMed Link: 26206375
Variant Present in the following documents:
  • 12859_2015_673_MOESM1_ESM.xls, sheet 1
View BVdb publication page



Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: TP53: A161F
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



DNA-bound platinum is the major determinant of cisplatin sensitivity in head and neck squamous carcinoma cells.

Plos One
Martens-de Kemp, Sanne R SR; Dalm, Simone U SU; Wijnolts, Fiona M J FM; Brink, Arjen A; Honeywell, Richard J RJ; Peters, Godefridus J GJ; Braakhuis, Boudewijn J M BJ; Brakenhoff, Ruud H RH
Publication Date: 2013

Variant appearance in text: TP53: A161F
PubMed Link: 23613873
Variant Present in the following documents:
View BVdb publication page