Monitoring Treatment Response, Early Recurrence, and Survival in Uterine Serous Carcinoma and Carcinosarcoma Patients Using Personalized Circulating Tumor DNA Biomarkers.
International Journal Of Molecular Sciences
Bellone, Stefania S; McNamara, Blair B; Mutlu, Levent L; Demirkiran, Cem C; Hartwich, Tobias Max Philipp TMP; Harold, Justin J; Yang-Hartwich, Yang Y; Siegel, Eric R ER; Santin, Alessandro D AD
Venetoclax Use in Paediatric Haemato-Oncology Centres in Poland: A 2022 Survey.
Children (Basel, Switzerland)
Bobeff, Katarzyna K; Pastorczak, Agata A; Urbanska, Zuzanna Z; Balwierz, Walentyna W; Juraszewska, Edyta E; Wachowiak, Jacek J; Derwich, Katarzyna K; Samborska, Magdalena M; Kalwak, Krzysztof K; Dachowska-Kalwak, Iwona I; Laguna, Paweł P; Malinowska, Iwona I; Smalisz, Katarzyna K; Gozdzik, Jolanta J; Oszer, Aleksandra A; Urbanski, Bartosz B; Zdunek, Maciej M; Szczepanski, Tomasz T; Mlynarski, Wojciech W; Janczar, Szymon S
Publication Date: 2023-04-19
Variant appearance in text: TP53: 469G>T; Val157Phe
Effectiveness of tislelizumab when combined with etoposide and carboplatin in patients with SMARCA4-deficient undifferentiated thoracic tumor: a case report.
Translational Cancer Research
Yang, Pan P; Xiong, Fu F; Lin, Yong Y; Liang, Peiqiang P; Tang, Chunlan C
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis.
Cell Death Discovery
Romanovsky, Eva E; Kluck, Klaus K; Ourailidis, Iordanis I; Menzel, Michael M; Beck, Susanne S; Ball, Markus M; Kazdal, Daniel D; Christopoulos, Petros P; Schirmacher, Peter P; Stiewe, Thorsten T; Stenzinger, Albrecht A; Budczies, Jan J
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Circulating Tumor DNA Monitoring Reveals Molecular Progression before Radiologic Progression in a Real-life Cohort of Patients with Advanced Non-small Cell Lung Cancer.
Cancer Research Communications
Frank, Malene S MS; Andersen, Christina S A CSA; Ahlborn, Lise B LB; Pallisgaard, Niels N; Bodtger, Uffe U; Gehl, Julie J
Neoadjuvant chemotherapy plus nivolumab with or without ipilimumab in operable non-small cell lung cancer: the phase 2 platform NEOSTAR trial.
Nature Medicine
Cascone, Tina T; Leung, Cheuk H CH; Weissferdt, Annikka A; Pataer, Apar A; Carter, Brett W BW; Godoy, Myrna C B MCB; Feldman, Hope H; William, William N WN; Xi, Yuanxin Y; Basu, Sreyashi S; Sun, Jing Jing JJ; Yadav, Shalini S SS; Rojas Alvarez, Frank R FR; Lee, Younghee Y; Mishra, Aditya K AK; Chen, Lili L; Pradhan, Monika M; Guo, Haiping H; Sinjab, Ansam A; Zhou, Nicolas N; Negrao, Marcelo V MV; Le, Xiuning X; Gay, Carl M CM; Tsao, Anne S AS; Byers, Lauren Averett LA; Altan, Mehmet M; Glisson, Bonnie S BS; Fossella, Frank V FV; Elamin, Yasir Y YY; Blumenschein, George G; Zhang, Jianjun J; Skoulidis, Ferdinandos F; Wu, Jia J; Mehran, Reza J RJ; Rice, David C DC; Walsh, Garrett L GL; Hofstetter, Wayne L WL; Rajaram, Ravi R; Antonoff, Mara B MB; Fujimoto, Junya J; Solis, Luisa M LM; Parra, Edwin R ER; Haymaker, Cara C; Wistuba, Ignacio I II; Swisher, Stephen G SG; Vaporciyan, Ara A AA; Lin, Heather Y HY; Wang, Jing J; Gibbons, Don L DL; Jack Lee, J J; Ajami, Nadim J NJ; Wargo, Jennifer A JA; Allison, James P JP; Sharma, Padmanee P; Kadara, Humam H; Heymach, John V JV; Sepesi, Boris B
Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.
Nature Medicine
Sturm, Dominik D; Capper, David D; Andreiuolo, Felipe F; Gessi, Marco M; Kölsche, Christian C; Reinhardt, Annekathrin A; Sievers, Philipp P; Wefers, Annika K AK; Ebrahimi, Azadeh A; Suwala, Abigail K AK; Gielen, Gerrit H GH; Sill, Martin M; Schrimpf, Daniel D; Stichel, Damian D; Hovestadt, Volker V; Daenekas, Bjarne B; Rode, Agata A; Hamelmann, Stefan S; Previti, Christopher C; Jäger, Natalie N; Buchhalter, Ivo I; Blattner-Johnson, Mirjam M; Jones, Barbara C BC; Warmuth-Metz, Monika M; Bison, Brigitte B; Grund, Kerstin K; Sutter, Christian C; Hirsch, Steffen S; Dikow, Nicola N; Hasselblatt, Martin M; Schüller, Ulrich U; Gerber, Nicolas U NU; White, Christine L CL; Buntine, Molly K MK; Kinross, Kathryn K; Algar, Elizabeth M EM; Hansford, Jordan R JR; Gottardo, Nicholas G NG; Hernáiz Driever, Pablo P; Gnekow, Astrid A; Witt, Olaf O; Müller, Hermann L HL; Calaminus, Gabriele G; Fleischhack, Gudrun G; Kordes, Uwe U; Mynarek, Martin M; Rutkowski, Stefan S; Frühwald, Michael C MC; Kramm, Christof M CM; von Deimling, Andreas A; Pietsch, Torsten T; Sahm, Felix F; Pfister, Stefan M SM; Jones, David T W DTW
Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.
Cancer Research Communications
White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C
Publication Date: 2022-09
Variant appearance in text: TP53: 469G>T; V157F; rs121912654
A generalizable machine learning framework for classifying DNA repair defects using ctDNA exomes.
Npj Precision Oncology
Ritch, Elie J EJ; Herberts, Cameron C; Warner, Evan W EW; Ng, Sarah W S SWS; Kwan, Edmond M EM; Bacon, Jack V W JVW; Bernales, Cecily Q CQ; Schönlau, Elena E; Fonseca, Nicolette M NM; Giri, Veda N VN; Maurice-Dror, Corinne C; Vandekerkhove, Gillian G; Jones, Steven J M SJM; Chi, Kim N KN; Wyatt, Alexander W AW
Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.
Nature Communications
Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI
C-Terminal p53 Palindromic Tetrapeptide Restores Full Apoptotic Function to Mutant p53 Cancer Cells In Vitro and In Vivo.
Biomedicines
Fine, Robert L RL; Mao, Yuehua Y; Dinnen, Richard R; Rosal, Ramon V RV; Raffo, Anthony A; Hochfeld, Uri U; Senatus, Patrick P; Bruce, Jeffrey N JN; Nichols, Gwen G; Wang, Hsin H; Li, Yongliang Y; Brandt-Rauf, Paul W PW
Clinical utility of liquid biopsy and integrative genomic profiling in early-stage and oligometastatic cancer patients treated with radiotherapy.
British Journal Of Cancer
Cifuentes, Guadalupe A GA; Santiago, Adrián A; Méndez Blanco, Lucía L; Fueyo, María M; López Martínez, Esther E; Soria, Raquel R; Martín López, Irene I; Cucarella Beltrán, Pepa P; Pardo-Coto, Pablo P; Rodriguez-Rubi, David D; Urquilla, Karla K; Durán, Noelia S NS; Álvarez, Rebeca R; Lago, Claudia G CG; Otero, Andrea A; Diñeiro, Marta M; Capín, Raquel R; Cadiñanos, Juan J; Cabanillas, Rubén R
Publication Date: 2022-12-22
Variant appearance in text: TP53: 469G>T; Val157Phe
Genomic heterogeneity as a barrier to precision oncology in urothelial cancer.
Cell Reports
Clinton, Timothy N TN; Chen, Ziyu Z; Wise, Hannah H; Lenis, Andrew T AT; Chavan, Shweta S; Donoghue, Mark T A MTA; Almassi, Nima N; Chu, Carissa E CE; Dason, Shawn S; Rao, Pavitra P; Rodrigues, James A JA; Vasani, Naresh B NB; Ridouani, Fourat F; Rosenberg, Jonathan E JE; Bajorin, Dean F DF; Teo, Min Yuen MY; Bochner, Bernard H BH; Berger, Michael F MF; Ostrovnaya, Irina I; Pietzak, Eugene J EJ; Iyer, Gopa G; Gao, Sizhi Paul SP; Hu, Wenhuo W; Al-Ahmadie, Hikmat A HA; Solit, David B DB
Metastatic colorectal cancer treatment response evaluation by ultra-deep sequencing of cell-free DNA and matched white blood cells.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
van 't Erve, Iris I; Medina, Jamie E JE; Leal, Alessandro A; Papp, Eniko E; Phallen, Jillian J; Adleff, Vilmos V; Chiao, Elaine Jiayuee EJ; Arun, Adith S AS; Bolhuis, Karen K; Simmons, John K JK; Karandikar, Aanavi A; Valkenburg, Kenneth C KC; Sausen, Mark M; Angiuoli, Samuel V SV; Scharpf, Robert B RB; Punt, Cornelis J A CJA; Meijer, Gerrit A GA; Velculescu, Victor E VE; Fijneman, Remond J A RJA
Remarkable Intracranial Response to Sotorasib in a Patient With KRAS G12C-Mutated Lung Adenocarcinoma and Untreated Brain Metastases: A Case Report.
Jto Clinical And Research Reports
Yeh, Justin J; Marks, Jennifer A JA; Alzeer, Ali H AH; Sloan, Emily A EA; Varghese, Reshma R; Paudel, Nitika N; Reuss, Joshua E JE; Bergquist, Peter J PJ; Liu, Stephen V SV; Kim, Chul C
Uterine lavage identifies cancer mutations and increased TP53 somatic mutation burden in individuals with ovarian cancer.
Cancer Research Communications
Ghezelayagh, Talayeh S TS; Kohrn, Brendan F BF; Fredrickson, Jeanne J; Manhardt, Enna E; Radke, Marc R MR; Katz, Ronit R; Gray, Heidi J HJ; Urban, Renata R RR; Pennington, Kathryn P KP; Liao, John B JB; Doll, Kemi M KM; Simons, Elise J EJ; Burzawa, Jennifer K JK; Goff, Barbara A BA; Speiser, Paul P; Swisher, Elizabeth M EM; Norquist, Barbara M BM; Risques, Rosa Ana RA
Challenges and opportunities associated with the MD Anderson IMPACT2 randomized study in precision oncology.
Npj Precision Oncology
Vo, Henry Hiep HH; Fu, Siqing S; Hong, David S DS; Karp, Daniel D DD; Piha-Paul, Sarina S; Subbiah, Vivek V; Janku, Filip F; Naing, Aung A; Yap, Timothy A TA; Rodon, Jordi J; Ajani, Jaffer A JA; Cartwright, Carrie C; Johnson, Amber A; Song, I-Wen IW; Beck, Jennifer J; Kahle, Michael M; Nogueras-Gonzalez, Graciela M GM; Miller, Vincent V; Chao, Calvin C; Vining, David J DJ; Berry, Donald A DA; Meric-Bernstam, Funda F; Tsimberidou, Apostolia-Maria AM
bMSAF is a prognostic predictor for advanced hepatocellular carcinoma patients treated with immune checkpoint inhibitor camrelizumab and anti-angiogenic agent apatinib combination therapy.