Publications:

---

A Simple and Affordable Method to Create Nonsense Mutation Clones of p53 for Studying the Premature Termination Codon Readthrough Activity of PTC124.

Biomedicines

Chen, Chia-Chi CC; Liao, Ruo-Yu RY; Yeh, Fang-Yu FY; Lin, Yu-Rou YR; Wu, Tze-You TY; Pastor, Alexa Escobar AE; Zul, Danny Danilo DD; Hsu, Yun-Chien YC; Wu, Kuan-Yo KY; Liu, Ke-Fang KF; Kannagi, Reiji R; Chen, Jang-Yi JY; Cai, Bi-He BH

Publication Date: 2023-04-28

Variant appearance in text: p53: W146X

PubMed Link: 37238980

Variant Present in the following documents:

• Main text
• biomedicines-11-01310.pdf

View BVdb publication page

---

Different impacts of TP53 mutations on cell cycle-related gene expression among cancer types.

Scientific Reports

Sasaki, Keiju K; Takahashi, Shin S; Ouchi, Kota K; Otsuki, Yasufumi Y; Wakayama, Shonosuke S; Ishioka, Chikashi C

Publication Date: 2023-03-24

Variant appearance in text: TP53: W146*

PubMed Link: 36964217

Variant Present in the following documents:

• 41598_2023_32092_MOESM1_ESM.xlsx, sheet 4

View BVdb publication page

---

A generalizable machine learning framework for classifying DNA repair defects using ctDNA exomes.

Npj Precision Oncology

Ritch, Elie J EJ; Herberts, Cameron C; Warner, Evan W EW; Ng, Sarah W S SWS; Kwan, Edmond M EM; Bacon, Jack V W JVW; Bernales, Cecily Q CQ; Schönlau, Elena E; Fonseca, Nicolette M NM; Giri, Veda N VN; Maurice-Dror, Corinne C; Vandekerkhove, Gillian G; Jones, Steven J M SJM; Chi, Kim N KN; Wyatt, Alexander W AW

Publication Date: 2023-03-13

Variant appearance in text: TP53: W146X

PubMed Link: 36914848

Variant Present in the following documents:

• 41698_2023_366_MOESM2_ESM.xlsx, sheet 4

View BVdb publication page

---

Discovering Synergistic Compounds with BYL-719 in PI3K Overactivated Basal-like PDXs.

Cancers

Boyd, David C DC; Zboril, Emily K EK; Olex, Amy L AL; Leftwich, Tess J TJ; Hairr, Nicole S NS; Byers, Holly A HA; Valentine, Aaron D AD; Altman, Julia E JE; Alzubi, Mohammad A MA; Grible, Jacqueline M JM; Turner, Scott A SA; Ferreira-Gonzalez, Andrea A; Dozmorov, Mikhail G MG; Harrell, J Chuck JC

Publication Date: 2023-03-03

Variant appearance in text: TP53: 438G>A

PubMed Link: 36900375

Variant Present in the following documents:

• cancers-15-01582.pdf

View BVdb publication page

---

Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics

Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P

Publication Date: 2023-02-23

Variant appearance in text: TP53: 438G>A; Trp146Ter

PubMed Link: 36823319

Variant Present in the following documents:

• 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

---

Tumor-informed or tumor-agnostic circulating tumor DNA as a biomarker for risk of recurrence in resected colorectal cancer patients.

Frontiers In Oncology

Chan, Hiu Ting HT; Nagayama, Satoshi S; Otaki, Masumi M; Chin, Yoon Ming YM; Fukunaga, Yosuke Y; Ueno, Masashi M; Nakamura, Yusuke Y; Low, Siew-Kee SK

Publication Date: 2022

Variant appearance in text: TP53: 438G>A; W146*

PubMed Link: 36776372

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 5
• DataSheet_1.xlsx, sheet 9
• DataSheet_1.xlsx, sheet 10

View BVdb publication page

---

Integrative proteomic characterization of adenocarcinoma of esophagogastric junction.

Nature Communications

Li, Shengli S; Yuan, Li L; Xu, Zhi-Yuan ZY; Xu, Jing-Li JL; Chen, Gui-Ping GP; Guan, Xiaoqing X; Pan, Guang-Zhao GZ; Hu, Can C; Dong, Jinyun J; Du, Yi-An YA; Yang, Li-Tao LT; Ni, Mao-Wei MW; Jiang, Rui-Bin RB; Zhu, Xiu X; Lv, Hang H; Xu, Han-Dong HD; Zhang, Sheng-Jie SJ; Qin, Jiang-Jiang JJ; Cheng, Xiang-Dong XD

Publication Date: 2023-02-11

Variant appearance in text: TP53: 438G>A; Trp146Ter; rs1131691026

PubMed Link: 36774361

Variant Present in the following documents:

• 41467_2023_36462_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

---

Exploring prognostic indicators in the pathological images of ovarian cancer based on a deep survival network.

Frontiers In Genetics

Wu, Meixuan M; Zhu, Chengguang C; Yang, Jiani J; Cheng, Shanshan S; Yang, Xiaokang X; Gu, Sijia S; Xu, Shilin S; Wu, Yongsong Y; Shen, Wei W; Huang, Shan S; Wang, Yu Y

Publication Date: 2022

Variant appearance in text: rs1131691026

PubMed Link: 36685892

Variant Present in the following documents:

• Table3.xlsx, sheet 1

View BVdb publication page

---

Germline and somatic variants in ovarian carcinoma: A next-generation sequencing (NGS) analysis.

Frontiers In Oncology

Andrikopoulou, Angeliki A; Zografos, Eleni E; Apostolidou, Kleoniki K; Kyriazoglou, Anastasios A; Papatheodoridi, Alksistis-Maria AM; Kaparelou, Maria M; Koutsoukos, Konstantinos K; Liontos, Michalis M; Dimopoulos, Meletios-Athanasios MA; Zagouri, Flora F

Publication Date: 2022

Variant appearance in text: TP53: 438G>A; Trp146Ter

PubMed Link: 36531003

Variant Present in the following documents:

• Main text
• fonc-12-1030786.pdf

View BVdb publication page

---

Whole-Exome Sequencing Among Chinese Patients With Hereditary Diffuse Gastric Cancer.

Jama Network Open

Liu, Ze-Xian ZX; Zhang, Xiao-Long XL; Zhao, Qi Q; Chen, Yungchang Y; Sheng, Hui H; He, Cai-Yun CY; Sun, Yu-Ting YT; Lai, Ming-Yu MY; Wu, Min-Qing MQ; Zuo, Zhi-Xiang ZX; Wang, Wei W; Zhou, Zhi-Wei ZW; Wang, Feng-Hua FH; Li, Yu-Hong YH; Xu, Rui-Hua RH; Qiu, Miao-Zhen MZ

Publication Date: 2022-12-01

Variant appearance in text: TP53: W146X

PubMed Link: 36484990

Variant Present in the following documents:

• jamanetwopen-e2245836-s002.xlsx, sheet 3

View BVdb publication page

---

The Autologous Hematopoietic Stem Cells Transplantation Combination-Based Chimeric Antigen Receptor T-Cell Therapy Improves Outcomes of Relapsed/Refractory Central Nervous System B-Cell Lymphoma.

Journal Of Oncology

Xue, Fei F; Zheng, Peihao P; Liu, Rui R; Feng, Shaomei S; Guo, Yuelu Y; Shi, Hui H; Liu, Haidi H; Deng, Biping B; Xu, Teng T; Ke, Xiaoyan X; Hu, Kai K

Publication Date: 2022

Variant appearance in text: TP53: W146X

PubMed Link: 36483984

Variant Present in the following documents:

• JO2022-2900310.pdf

View BVdb publication page

---

Mitomycin C in Homologous Recombination Deficient Metastatic Pancreatic Cancer after Disease Progression on Platinum-Based Chemotherapy and Olaparib.

Biomedicines

Botrus, Gehan G; Roe, Denise D; Jameson, Gayle S GS; Junior, Pedro Luiz Serrano Uson PLSU; Korn, Ronald Lee RL; Caldwell, Lana L; Bargenquast, Taylor T; Miller, Max M; Borazanci, Erkut Hasan EH

Publication Date: 2022-10-26

Variant appearance in text: TP53: W146X

PubMed Link: 36359225

Variant Present in the following documents:

• Main text
• biomedicines-10-02705.pdf

View BVdb publication page

---

NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.

Cell Reports

Ramakrishnan, Gopalakrishnan G; Parajuli, Parash P; Singh, Pura P; Friend, Creighton C; Hurwitz, Eric E; Prunier, Celine C; Razzaque, Mohammed S MS; Xu, Keli K; Atfi, Azeddine A

Publication Date: 2022-11-08

Variant appearance in text: TP53: W146*

PubMed Link: 36351408

Variant Present in the following documents:

• NIHMS1848910-supplement-2.xlsx, sheet 3
• NIHMS1848910-supplement-2.xlsx, sheet 2

View BVdb publication page

---

Personalized ctDNA micro-panels can monitor and predict clinical outcomes for patients with triple-negative breast cancer.

Scientific Reports

Barnell, Erica K EK; Fisk, Bryan B; Skidmore, Zachary L ZL; Cotto, Kelsy C KC; Basu, Anamika A; Anand, Aparna A; Richters, Megan M MM; Luo, Jingqin J; Fronick, Catrina C; Anurag, Meenakshi M; Fulton, Robert R; Ellis, Matthew J MJ; Griffith, Obi L OL; Griffith, Malachi M; Ademuyiwa, Foluso O FO

Publication Date: 2022-10-22

Variant appearance in text: TP53: 438G>A; Trp146Ter; rs1131691026

PubMed Link: 36273232

Variant Present in the following documents:

• 41598_2022_20928_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Whole-genome analysis identifies novel drivers and high-risk double-hit events in relapsed/refractory myeloma.

Blood

Ansari-Pour, Naser N; Samur, Mehmet K MK; Flynt, Erin E; Gooding, Sarah S; Towfic, Fadi F; Stong, Nicholas N; Ortiz Estevez, Maria M; Mavrommatis, Konstantinos K; Walker, Brian A BA; Morgan, Gareth J GJ; Munshi, Nikhil C NC; Avet Loiseau, Herve H; Thakurta, Anjan A

Publication Date: 2022-10-12

Variant appearance in text: TP53: W146X

PubMed Link: 36223594

Variant Present in the following documents:

• BLOOD_BLD-2022-017010-mmc2.xlsx, sheet 1

View BVdb publication page

---

Integrated cohort of esophageal squamous cell cancer reveals genomic features underlying clinical characteristics.

Nature Communications

Li, Minghao M; Zhang, Zicheng Z; Wang, Qianrong Q; Yi, Yan Y; Li, Baosheng B

Publication Date: 2022-09-07

Variant appearance in text: TP53: W146X

PubMed Link: 36071046

Variant Present in the following documents:

• 41467_2022_32962_MOESM15_ESM.xlsx, sheet 22

View BVdb publication page

---

Exploiting gene dependency to inform drug development for multiple myeloma.

Scientific Reports

Went, Molly M; Hoang, Phuc H PH; Law, Philip J PJ; Kaiser, Martin F MF; Houlston, Richard S RS

Publication Date: 2022-07-26

Variant appearance in text: TP53: W146X

PubMed Link: 35882937

Variant Present in the following documents:

• 41598_2022_16940_MOESM2_ESM.xlsx, sheet 8

View BVdb publication page

---

Landscape of somatic alterations in large-scale solid tumors from an Asian population.

Nature Communications

Wu, Liqun L; Yao, Herui H; Chen, Hui H; Wang, Aodi A; Guo, Kun K; Gou, Wenli W; Yu, Yanfei Y; Li, Xiang X; Yao, Ming M; Yuan, Shaohua S; Pang, Fei F; Hu, Jinwei J; Chen, Lijuan L; Liu, Wenjin W; Yao, Jicheng J; Zhang, Shuirong S; Dong, Xiaowei X; Wang, Weifeng W; Hu, Jing J; Ling, Qi Q; Ding, Songming S; Wei, Yan Y; Li, Qiang Q; Cao, Weichun W; Wang, Shuang S; Di, Yang Y; Feng, Feiling F; Zhao, Gang G; Zhang, Jian J; Huang, Ling L; Xu, Jia J; Yan, Wangjun W; Tong, Zhongsheng Z; Jiang, Da D; Ji, Tao T; Li, Qiao Q; Xu, Ling L; He, Huiying H; Shang, Liang L; Liu, Jin J; Wang, Kefeng K; Wu, Duoguang D; Shen, Jingnan J; Liu, Ye Y; Zhang, Ting T; Liang, Chaojie C; Wang, Yusheng Y; Shang, Yanhong Y; Guo, Jianji J; Liang, Guanbiao G; Xu, Shifeng S; Liu, Junfeng J; Wang, Kai K; Wang, Minghui M

Publication Date: 2022-07-23

Variant appearance in text: TP53: W146*

PubMed Link: 35871175

Variant Present in the following documents:

• 41467_2022_31780_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

---

Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: TP53: 438G>A; W146*

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

---

The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma.

Nature Communications

Vo, Josh N JN; Wu, Yi-Mi YM; Mishler, Jeanmarie J; Hall, Sarah S; Mannan, Rahul R; Wang, Lisha L; Ning, Yu Y; Zhou, Jin J; Hopkins, Alexander C AC; Estill, James C JC; Chan, Wallace K B WKB; Yesil, Jennifer J; Cao, Xuhong X; Rao, Arvind A; Tsodikov, Alexander A; Talpaz, Moshe M; Cole, Craig E CE; Ye, Jing C JC; , ; Bergsagel, P Leif PL; Auclair, Daniel D; Cho, Hearn Jay HJ; Robinson, Dan R DR; Chinnaiyan, Arul M AM

Publication Date: 2022-06-29

Variant appearance in text: TP53: 438G>A; Trp146*

PubMed Link: 35768438

Variant Present in the following documents:

• 41467_2022_31430_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

---

Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: TP53: W146*

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

---

The longitudinal dynamics and natural history of clonal haematopoiesis.

Nature

Fabre, Margarete A MA; de Almeida, José Guilherme JG; Fiorillo, Edoardo E; Mitchell, Emily E; Damaskou, Aristi A; Rak, Justyna J; Orrù, Valeria V; Marongiu, Michele M; Chapman, Michael Spencer MS; Vijayabaskar, M S MS; Baxter, Joanna J; Hardy, Claire C; Abascal, Federico F; Williams, Nicholas N; Nangalia, Jyoti J; Martincorena, Iñigo I; Campbell, Peter J PJ; McKinney, Eoin F EF; Cucca, Francesco F; Gerstung, Moritz M; Vassiliou, George S GS

Publication Date: 2022-06

Variant appearance in text: TP53: W146X

PubMed Link: 35650444

Variant Present in the following documents:

• 41586_2022_4785_MOESM13_ESM.xlsx, sheet 3
• 41586_2022_4785_MOESM11_ESM.xlsx, sheet 1
• 41586_2022_4785_MOESM9_ESM.xlsx, sheet 1

View BVdb publication page

---

Clinical and molecular validation of BAP1, MTAP, P53, and Merlin immunohistochemistry in diagnosis of pleural mesothelioma.

Modern Pathology : An Official Journal Of The United States And Canadian Academy Of Pathology, Inc

Chapel, David B DB; Hornick, Jason L JL; Barlow, Julianne J; Bueno, Raphael R; Sholl, Lynette M LM

Publication Date: 2022-10

Variant appearance in text: TP53: W146*

PubMed Link: 35459788

Variant Present in the following documents:

• nihms-1793523.pdf

View BVdb publication page

---

Culture and multiomic analysis of lung cancer patient-derived pleural effusions revealed distinct druggable molecular types.

Scientific Reports

Seo, Ha-Young HY; Kim, Soon-Chan SC; Roh, Woo-Lee WL; Shin, Young-Kyoung YK; Kim, Soyeon S; Kim, Dong-Wan DW; Kim, Tae Min TM; Ku, Ja-Lok JL

Publication Date: 2022-04-15

Variant appearance in text: TP53: W146*

PubMed Link: 35428753

Variant Present in the following documents:

• Main text
• 41598_2022_Article_10318.pdf

View BVdb publication page

---

Molecular landscape of TP53 mutations in breast cancer and their utility for predicting the response to HER-targeted therapy in HER2 amplification-positive and HER2 mutation-positive amplification-negative patients.

Cancer Medicine

Liu, Binliang B; Yi, Zongbi Z; Guan, Yanfang Y; Ouyang, Quchang Q; Li, Chunxiao C; Guan, Xiuwen X; Lv, Dan D; Li, Lixi L; Zhai, Jingtong J; Qian, Haili H; Xu, Binghe B; Ma, Fei F; Zeng, Yixin Y

Publication Date: 2022-07

Variant appearance in text: TP53: 438G>A; W146*

PubMed Link: 35393784

Variant Present in the following documents:

• CAM4-11-2767-s001.xlsx, sheet 1

View BVdb publication page

---

A Custom DNA-Based NGS Panel for the Molecular Characterization of Patients With Diffuse Gliomas: Diagnostic and Therapeutic Applications.

Frontiers In Oncology

Tirrò, Elena E; Massimino, Michele M; Broggi, Giuseppe G; Romano, Chiara C; Minasi, Simone S; Gianno, Francesca F; Antonelli, Manila M; Motta, Gianmarco G; Certo, Francesco F; Altieri, Roberto R; Manzella, Livia L; Caltabiano, Rosario R; Barbagallo, Giuseppe Maria Vincenzo GMV; Buttarelli, Francesca Romana FR; Magro, Gaetano G; Giangaspero, Felice F; Vigneri, Paolo P

Publication Date: 2022

Variant appearance in text: TP53: Trp146Ter

PubMed Link: 35372034

Variant Present in the following documents:

• Main text
• fonc-12-861078.pdf

View BVdb publication page

---

Clinical utility of comprehensive genomic profiling in Japan: Result of PROFILE-F study.

Plos One

Aoyagi, Yasuko Y; Kano, Yoshihito Y; Tohyama, Kohki K; Matsudera, Shotaro S; Kumaki, Yuichi Y; Takahashi, Kenta K; Mitsumura, Takahiro T; Harada, Yohei Y; Sato, Akemi A; Nakamura, Hideaki H; Sueoka, Eisaburo E; Aragane, Naoko N; Kimura, Koichiro K; Onishi, Iichiro I; Takemoto, Akira A; Akahoshi, Keiichi K; Ono, Hiroaki H; Ishikawa, Toshiaki T; Tokunaga, Masanori M; Nakagawa, Tsuyoshi T; Oshima, Noriko N; Nakamura, Reiko R; Takagi, Masatoshi M; Asakage, Takahiro T; Uetake, Hiroyuki H; Tanabe, Minoru M; Miyake, Satoshi S; Kinugasa, Yusuke Y; Ikeda, Sadakatsu S

Publication Date: 2022

Variant appearance in text: TP53: W146*

PubMed Link: 35358259

Variant Present in the following documents:

• pone.0266112.s001.xlsx, sheet 1

View BVdb publication page

---

The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification.

Bmc Cancer

Yang, Yefan Y; Ding, Ying Y; Gong, Yuxi Y; Zhao, Sha S; Li, Mingna M; Li, Xiao X; Song, Guoxin G; Zhai, Boya B; Liu, Jin J; Shao, Yang Y; Zhu, Liuqing L; Pang, Jiaohui J; Ma, Yutong Y; Ou, Qiuxiang Q; Wu, Xue X; Zhang, Zhihong Z

Publication Date: 2022-02-18

Variant appearance in text: TP53: 438G>A; W146*

PubMed Link: 35180847

Variant Present in the following documents:

• 12885_2022_9279_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

---

Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.

Nature Biotechnology

Sánchez-Rivera, Francisco J FJ; Diaz, Bianca J BJ; Kastenhuber, Edward R ER; Schmidt, Henri H; Katti, Alyna A; Kennedy, Margaret M; Tem, Vincent V; Ho, Yu-Jui YJ; Leibold, Josef J; Paffenholz, Stella V SV; Barriga, Francisco M FM; Chu, Kevan K; Goswami, Sukanya S; Wuest, Alexandra N AN; Simon, Janelle M JM; Tsanov, Kaloyan M KM; Chakravarty, Debyani D; Zhang, Hongxin H; Leslie, Christina S CS; Lowe, Scott W SW; Dow, Lukas E LE

Publication Date: 2022-06

Variant appearance in text: TP53: W146*

PubMed Link: 35165384

Variant Present in the following documents:

• NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 4
• NIHMS1760571-supplement-Supplementary_Table_S2.xlsx, sheet 6
• NIHMS1760571-supplement-Supplementary_Table_S7.xlsx, sheet 5

View BVdb publication page

---

Comparison of acute myeloid leukemia and myelodysplastic syndromes with TP53 aberrations.

Annals Of Hematology

Dutta, Sayantanee S; Moritz, Jennifer J; Pregartner, Gudrun G; Thallinger, Gerhard G GG; Brandstätter, Ilona I; Lind, Karin K; Rezania, Simin S; Lyssy, Freya F; Reinisch, Andreas A; Zebisch, Armin A; Berghold, Andrea A; Wölfler, Albert A; Sill, Heinz H

Publication Date: 2022-04

Variant appearance in text: TP53: W146*

PubMed Link: 35083527

Variant Present in the following documents:

• 277_2022_4766_MOESM1_ESM.pdf

View BVdb publication page

---

The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma.

Bmc Cancer

Karachaliou, Georgia Sofia GS; Alkallas, Rached R; Carroll, Sarah B SB; Caressi, Chongshan C; Zakria, Danny D; Patel, Nirali M NM; Trembath, Dimitri G DG; Ezzell, Jennifer A JA; Pegna, Guillaume J GJ; Googe, Paul B PB; Galeotti, Jonathan P JP; Ayvali, Fatih F; Collichio, Frances A FA; Lee, Carrie B CB; Ollila, David W DW; Gulley, Margaret L ML; Johnson, Douglas B DB; Kim, Kevin B KB; Watson, Ian R IR; Moschos, Stergios J SJ

Publication Date: 2022-01-05

Variant appearance in text: TP53: W146*

PubMed Link: 34986841

Variant Present in the following documents:

• 12885_2021_8908_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

The clinical significance of adenomatous polyposis coli (APC) and catenin Beta 1 (CTNNB1) genetic aberrations in patients with melanoma.

Bmc Cancer

Karachaliou, Georgia Sofia GS; Alkallas, Rached R; Carroll, Sarah B SB; Caressi, Chongshan C; Zakria, Danny D; Patel, Nirali M NM; Trembath, Dimitri G DG; Ezzell, Jennifer A JA; Pegna, Guillaume J GJ; Googe, Paul B PB; Galeotti, Jonathan P JP; Ayvali, Fatih F; Collichio, Frances A FA; Lee, Carrie B CB; Ollila, David W DW; Gulley, Margaret L ML; Johnson, Douglas B DB; Kim, Kevin B KB; Watson, Ian R IR; Moschos, Stergios J SJ

Publication Date: 2022-01-05

Variant appearance in text: TP53: W146*

PubMed Link: 34986841

Variant Present in the following documents:

• 12885_2021_8908_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples.

Communications Biology

Ikegami, Masachika M; Kohsaka, Shinji S; Hirose, Takeshi T; Ueno, Toshihide T; Inoue, Satoshi S; Kanomata, Naoki N; Yamauchi, Hideko H; Mori, Taisuke T; Sekine, Shigeki S; Inamoto, Yoshihiro Y; Yatabe, Yasushi Y; Kobayashi, Hiroshi H; Tanaka, Sakae S; Mano, Hiroyuki H

Publication Date: 2021-12-15

Variant appearance in text: TP53: 438G>A; Trp146*

PubMed Link: 34912045

Variant Present in the following documents:

• 42003_2021_2930_MOESM4_ESM.xlsx, sheet 6
• 42003_2021_2930_MOESM4_ESM.xlsx, sheet 7

View BVdb publication page

---

MicroSEC filters sequence errors for formalin-fixed and paraffin-embedded samples.

Communications Biology

Ikegami, Masachika M; Kohsaka, Shinji S; Hirose, Takeshi T; Ueno, Toshihide T; Inoue, Satoshi S; Kanomata, Naoki N; Yamauchi, Hideko H; Mori, Taisuke T; Sekine, Shigeki S; Inamoto, Yoshihiro Y; Yatabe, Yasushi Y; Kobayashi, Hiroshi H; Tanaka, Sakae S; Mano, Hiroyuki H

Publication Date: 2021-12-15

Variant appearance in text: TP53: 438G>A; Trp146*

PubMed Link: 34912045

Variant Present in the following documents:

• 42003_2021_2930_MOESM4_ESM.xlsx, sheet 7
• 42003_2021_2930_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

---

Circulating Tumor DNA as a Predictive Marker of Recurrence for Patients With Stage II-III Breast Cancer Treated With Neoadjuvant Therapy.

Frontiers In Oncology

Lin, Po-Han PH; Wang, Ming-Yang MY; Lo, Chiao C; Tsai, Li-Wei LW; Yen, Tzu-Chun TC; Huang, Thomas Yoyan TY; Huang, Wei-Chih WC; Yang, Karen K; Chen, Chih-Kai CK; Fan, Sheng-Chih SC; Kuo, Sung-Hsin SH; Huang, Chiun-Sheng CS

Publication Date: 2021

Variant appearance in text: TP53: W146X

PubMed Link: 34868925

Variant Present in the following documents:

• DataSheet_1.pdf

View BVdb publication page

---

Genomic Landscape in Neoplasm-Like Stroma Reveals Distinct Prognostic Subtypes of Pancreatic Ductal Adenocarcinoma.

Frontiers In Oncology

Jiang, Jiahong J; Xu, Yaping Y; Chang, Lianpeng L; Ru, Guoqing G; Xia, Xuefeng X; Yang, Ling L; Yi, Xin X; Chen, Zheling Z; Huang, Dong-Sheng DS; Yang, Liu L

Publication Date: 2021

Variant appearance in text: TP53: 438G>A; W146*

PubMed Link: 34733795

Variant Present in the following documents:

• Table_1.xlsx, sheet 1

View BVdb publication page

---

CDKN2A loss-of-function predicts immunotherapy resistance in non-small cell lung cancer.

Scientific Reports

Gutiontov, Stanley I SI; Turchan, William Tyler WT; Spurr, Liam F LF; Rouhani, Sherin J SJ; Chervin, Carolina Soto CS; Steinhardt, George G; Lager, Angela M AM; Wanjari, Pankhuri P; Malik, Renuka R; Connell, Philip P PP; Chmura, Steven J SJ; Juloori, Aditya A; Hoffman, Philip C PC; Ferguson, Mark K MK; Donington, Jessica S JS; Patel, Jyoti D JD; Vokes, Everett E EE; Weichselbaum, Ralph R RR; Bestvina, Christine M CM; Segal, Jeremy P JP; Pitroda, Sean P SP

Publication Date: 2021-10-08

Variant appearance in text: TP53: 438G>A; W146*

PubMed Link: 34625620

Variant Present in the following documents:

• 41598_2021_99524_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

---

Acquisition of aneuploidy drives mutant p53-associated gain-of-function phenotypes.

Nature Communications

Redman-Rivera, Lindsay N LN; Shaver, Timothy M TM; Jin, Hailing H; Marshall, Clayton B CB; Schafer, Johanna M JM; Sheng, Quanhu Q; Hongo, Rachel A RA; Beckermann, Kathryn E KE; Wheeler, Ferrin C FC; Lehmann, Brian D BD; Pietenpol, Jennifer A JA

Publication Date: 2021-08-31

Variant appearance in text: TP53: W146*

PubMed Link: 34465782

Variant Present in the following documents:

• 41467_2021_25359_MOESM5_ESM.xlsx, sheet 30

View BVdb publication page

---

Comparative analysis of nuclear and mitochondrial DNA from tissue and liquid biopsies of colorectal cancer patients.

Scientific Reports

Haupts, Anna A; Vogel, Anne A; Foersch, Sebastian S; Hartmann, Monika M; Maderer, Annett A; Wachter, Nicolas N; Huber, Tobias T; Kneist, Werner W; Roth, Wilfried W; Lang, Hauke H; Moehler, Markus M; Hartmann, Nils N

Publication Date: 2021-08-18

Variant appearance in text: TP53: 438G>A; Trp146*; rs1131691026

PubMed Link: 34408162

Variant Present in the following documents:

• Main text
• 41598_2021_95006_MOESM1_ESM.xlsx, sheet 2
• 41598_2021_95006_MOESM1_ESM.xlsx, sheet 1
• 41598_2021_Article_95006.pdf

View BVdb publication page

---

Incidental findings from cancer next generation sequencing panels.

Npj Genomic Medicine

Maani, Nika N; Panabaker, Karen K; McCuaig, Jeanna M JM; Buckley, Kathleen K; Semotiuk, Kara K; Farncombe, Kirsten M KM; Ainsworth, Peter P; Panchal, Seema S; Sadikovic, Bekim B; Armel, Susan Randall SR; Lin, Hanxin H; Kim, Raymond H RH

Publication Date: 2021-07-19

Variant appearance in text: TP53: Trp146*

PubMed Link: 34282142

Variant Present in the following documents:

• Main text
• 41525_2021_Article_224.pdf

View BVdb publication page

---

A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports

Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM

Publication Date: 2021-07-12

Variant appearance in text: TP53: 438G>A; W146*

PubMed Link: 34253785

Variant Present in the following documents:

• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 7
• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 9
• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 10

View BVdb publication page

---

Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.

Nature Communications

He, Chen C; Xu, Ke K; Zhu, Xiaoyan X; Dunphy, Paige S PS; Gudenas, Brian B; Lin, Wenwei W; Twarog, Nathaniel N; Hover, Laura D LD; Kwon, Chang-Hyuk CH; Kasper, Lawryn H LH; Zhang, Junyuan J; Li, Xiaoyu X; Dalton, James J; Jonchere, Barbara B; Mercer, Kimberly S KS; Currier, Duane G DG; Caufield, William W; Wang, Yingzhe Y; Xie, Jia J; Broniscer, Alberto A; Wetmore, Cynthia C; Upadhyaya, Santhosh A SA; Qaddoumi, Ibrahim I; Klimo, Paul P; Boop, Frederick F; Gajjar, Amar A; Zhang, Jinghui J; Orr, Brent A BA; Robinson, Giles W GW; Monje, Michelle M; Freeman Iii, Burgess B BB; Roussel, Martine F MF; Northcott, Paul A PA; Chen, Taosheng T; Rankovic, Zoran Z; Wu, Gang G; Chiang, Jason J; Tinkle, Christopher L CL; Shelat, Anang A AA; Baker, Suzanne J SJ

Publication Date: 2021-07-02

Variant appearance in text: TP53: W146*

PubMed Link: 34215733

Variant Present in the following documents:

• 41467_2021_24168_MOESM5_ESM.xlsx, sheet 3

View BVdb publication page

---

Comparison of two targeted ultra-deep sequencing technologies for analysis of plasma circulating tumour DNA in endocrine-therapy-resistant breast cancer patients.

Breast Cancer Research And Treatment

Nteliopoulos, Georgios G; Page, Karen K; Hills, Allison A; Howarth, Karen K; Emmett, Warren W; Green, Emma E; Martinson, Luke J LJ; Fernadez-Garcia, Daniel D; Hastings, Robert R; Guttery, David S DS; Kenny, Laura L; Stebbing, Justin J; Cleator, Susan S; Rehman, Farah F; Gleason, Kelly L T KLT; Sanela, Andrijac A; Ion, Charlotte C; Rushton, Amelia J AJ; Rosenfeld, Nitzan N; Coombes, R Charles RC; Shaw, Jacqueline A JA

Publication Date: 2021-07

Variant appearance in text: TP53: W146*

PubMed Link: 34097174

Variant Present in the following documents:

• 10549_2021_6220_MOESM2_ESM.xlsx, sheet 1
• 10549_2021_6220_MOESM2_ESM.xlsx, sheet 2

View BVdb publication page

---

Plasma Circulating Tumor DNA Sequencing Predicts Minimal Residual Disease in Resectable Esophageal Squamous Cell Carcinoma.

Frontiers In Oncology

Liu, Tao T; Yao, Qianqian Q; Jin, Hai H

Publication Date: 2021

Variant appearance in text: TP53: 438G>A

PubMed Link: 34094900

Variant Present in the following documents:

• Main text
• DataSheet_1.xlsx, sheet 3
• DataSheet_1.xlsx, sheet 6
• fonc-11-616209.pdf

View BVdb publication page

---

Whole-exome sequencing in eccrine porocarcinoma indicates promising therapeutic strategies.

Cancer Gene Therapy

Denisova, Evgeniya E; Westphal, Dana D; Surowy, Harald M HM; Meier, Friedegund F; Hutter, Barbara B; Reifenberger, Julia J; Rütten, Arno A; Schulz, Alexander A; Sergon, Mildred M; Ziemer, Mirjana M; Brors, Benedikt B; Betz, Regina C RC; Redler, Silke S

Publication Date: 2022-06

Variant appearance in text: TP53: 438G>A; W146X

PubMed Link: 34045664

Variant Present in the following documents:

• 41417_2021_347_MOESM4_ESM.xls, sheet 6

View BVdb publication page

---

A case report of microsatellite instability (MSI)-high, HER2 amplified pancreatic adenocarcinoma with central nervous system metastasis.

Ame Case Reports

DeVito, Nicholas C NC; Kelleher, Colm C; Strickland, Kyle C KC; Abbruzzese, James J; Anders, Carey C; Hanks, Brent A BA; Jia, Jingquan J; Mettu, Niharika B NB; Morse, Michael A MA; O'Neill, Margot M; Uronis, Hope H; Zafar, Yousuf Y; Strickler, John H JH

Publication Date: 2021

Variant appearance in text: TP53: W146*

PubMed Link: 33912803

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A genetically defined signature of responsiveness to erlotinib in early-stage pancreatic cancer patients: Results from the CONKO-005 trial.

Ebiomedicine

Hoyer, K K; Hablesreiter, R R; Inoue, Y Y; Yoshida, K K; Briest, F F; Christen, F F; Kakiuchi, N N; Yoshizato, T T; Shiozawa, Y Y; Shiraishi, Y Y; Striefler, J K JK; Bischoff, S S; Lohneis, P P; Putter, H H; Blau, O O; Keilholz, U U; Bullinger, L L; Pelzer, U U; Hummel, M M; Riess, H H; Ogawa, S S; Sinn, M M; Damm, F F

Publication Date: 2021-04

Variant appearance in text: TP53: W146X

PubMed Link: 33862582

Variant Present in the following documents:

• mmc3.xlsx, sheet 2

View BVdb publication page

---

Comprehensive omic characterization of breast cancer in Mexican-Hispanic women.

Nature Communications

Romero-Cordoba, Sandra L SL; Salido-Guadarrama, Ivan I; Rebollar-Vega, Rosa R; Bautista-Piña, Veronica V; Dominguez-Reyes, Carlos C; Tenorio-Torres, Alberto A; Villegas-Carlos, Felipe F; Fernández-López, Juan C JC; Uribe-Figueroa, Laura L; Alfaro-Ruiz, Luis L; Hidalgo-Miranda, Alfredo A

Publication Date: 2021-04-14

Variant appearance in text: TP53: W146*

PubMed Link: 33854067

Variant Present in the following documents:

• 41467_2021_22478_MOESM8_ESM.xlsx, sheet 9
• 41467_2021_22478_MOESM8_ESM.xlsx, sheet 11

View BVdb publication page

---

Profiling of circulating tumor DNA and tumor tissue for treatment selection in patients with advanced and refractory carcinoma: a prospective, two-stage phase II Individualized Cancer Treatment trial.

Therapeutic Advances In Medical Oncology

Riedl, Jakob M JM; Hasenleithner, Samantha O SO; Pregartner, Gudrun G; Scheipner, Lukas L; Posch, Florian F; Groller, Karin K; Kashofer, Karl K; Jahn, Stephan W SW; Bauernhofer, Thomas T; Pichler, Martin M; Stöger, Herbert H; Berghold, Andrea A; Hoefler, Gerald G; Speicher, Michael R MR; Heitzer, Ellen E; Gerger, Armin A

Publication Date: 2021

Variant appearance in text: TP53: Trp146*

PubMed Link: 33717225

Variant Present in the following documents:

• sj-pdf-1-tam-10.1177_1758835920987658.pdf

View BVdb publication page

---

BRAF AMP Frequently Co-occurs With IDH1/2, TP53, and ATRX Mutations in Adult Patients With Gliomas and Is Associated With Poorer Survival Than That of Patients Harboring BRAF V600E.

Frontiers In Oncology

Da, Rong R; Wang, Maode M; Jiang, Haitao H; Wang, Tuo T; Wang, Wei W

Publication Date: 2020

Variant appearance in text: TP53: W146*

PubMed Link: 33489866

Variant Present in the following documents:

• Table_1.xlsx, sheet 1

View BVdb publication page

---

The Genomic Landscape of Actinic Keratosis.

The Journal Of Investigative Dermatology

Thomson, Jason J; Bewicke-Copley, Findlay F; Anene, Chinedu Anthony CA; Gulati, Abha A; Nagano, Ai A; Purdie, Karin K; Inman, Gareth J GJ; Proby, Charlotte M CM; Leigh, Irene M IM; Harwood, Catherine A CA; Wang, Jun J

Publication Date: 2021-07

Variant appearance in text: TP53: 438G>A; W146*

PubMed Link: 33482222

Variant Present in the following documents:

• mmc1.xlsx, sheet 4

View BVdb publication page

---

Topsentinol L Trisulfate, a Marine Natural Product That Targets Basal-like and Claudin-Low Breast Cancers.

Marine Drugs

El-Chaar, Nader N NN; Smith, Thomas E TE; Shrestha, Gajendra G; Piccolo, Stephen R SR; Harper, Mary Kay MK; Van Wagoner, Ryan M RM; Lu, Zhenyu Z; Venancio, Ashlee R AR; Ireland, Chris M CM; Bild, Andrea H AH; Moos, Philip J PJ

Publication Date: 2021-01-18

Variant appearance in text: p53: W146*

PubMed Link: 33477536

Variant Present in the following documents:

• marinedrugs-19-00041-s001.pdf

View BVdb publication page

---

Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories.

Open Biology

Hynds, Robert E RE; Frese, Kristopher K KK; Pearce, David R DR; Grönroos, Eva E; Dive, Caroline C; Swanton, Charles C

Publication Date: 2021-01

Variant appearance in text: TP53: Trp146Ter

PubMed Link: 33435818

Variant Present in the following documents:

• Main text

View BVdb publication page

---

A comprehensive analysis of somatic alterations in Chinese ovarian cancer patients.

Scientific Reports

Zhang, Yingli Y; Shi, Xiaoliang X; Zhang, Jiejie J; Chen, Xi X; Zhang, Peng P; Liu, Angen A; Zhu, Tao T

Publication Date: 2021-01-11

Variant appearance in text: TP53: 438G>A; W146*

PubMed Link: 33432021

Variant Present in the following documents:

• 41598_2020_79694_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

---

Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer.

Nature Communications

Vandekerkhove, Gillian G; Lavoie, Jean-Michel JM; Annala, Matti M; Murtha, Andrew J AJ; Sundahl, Nora N; Walz, Simon S; Sano, Takeshi T; Taavitsainen, Sinja S; Ritch, Elie E; Fazli, Ladan L; Hurtado-Coll, Antonio A; Wang, Gang G; Nykter, Matti M; Black, Peter C PC; Todenhöfer, Tilman T; Ost, Piet P; Gibb, Ewan A EA; Chi, Kim N KN; Eigl, Bernhard J BJ; Wyatt, Alexander W AW

Publication Date: 2021-01-08

Variant appearance in text: TP53: W146X

PubMed Link: 33420073

Variant Present in the following documents:

• 41467_2020_20493_MOESM3_ESM.xlsx, sheet 4
• 41467_2020_20493_MOESM3_ESM.xlsx, sheet 7

View BVdb publication page

---

Mutation profile of non-small cell lung cancer revealed by next generation sequencing.

Respiratory Research

Chang, Ya-Sian YS; Tu, Siang-Jyun SJ; Chen, Yu-Chia YC; Liu, Ting-Yuan TY; Lee, Ya-Ting YT; Yen, Ju-Chen JC; Fang, Hsin-Yuan HY; Chang, Jan-Gowth JG

Publication Date: 2021-01-06

Variant appearance in text: TP53: W146X

PubMed Link: 33407425

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: TP53: 438G>A; W146*

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

---

Chromosome 2q gain and epigenetic silencing of GATA3 in microglandular adenosis of the breast.

The Journal Of Pathology. Clinical Research

Radner, Martin M; van Luttikhuizen, Jana Lisa JL; Bartels, Stephan S; Bublitz, Janin J; Grote, Isabel I; Rieger, Luisa L; Christgen, Henriette H; Stark, Helge H; Werlein, Christopher C; Lafos, Marcel M; Steinemann, Doris D; Lehmann, Ulrich U; Christgen, Matthias M; Kreipe, Hans H

Publication Date: 2021-05

Variant appearance in text: TP53: W146*

PubMed Link: 33382535

Variant Present in the following documents:

• Main text
• CJP2-7-220.pdf
• CJP2-7-220-s002.xlsx, sheet 9

View BVdb publication page

---

Chromosome 2q gain and epigenetic silencing of GATA3 in microglandular adenosis of the breast.

The Journal Of Pathology. Clinical Research

Radner, Martin M; van Luttikhuizen, Jana Lisa JL; Bartels, Stephan S; Bublitz, Janin J; Grote, Isabel I; Rieger, Luisa L; Christgen, Henriette H; Stark, Helge H; Werlein, Christopher C; Lafos, Marcel M; Steinemann, Doris D; Lehmann, Ulrich U; Christgen, Matthias M; Kreipe, Hans H

Publication Date: 2021-05

Variant appearance in text: TP53: W146*

PubMed Link: 33382535

Variant Present in the following documents:

• Main text
• CJP2-7-220.pdf
• CJP2-7-220-s002.xlsx, sheet 9

View BVdb publication page

---