Publications:

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Reducing MYC's transcriptional footprint unveils a good prognostic gene signature in melanoma.

Genes & Development

Zacarías-Fluck, Mariano F MF; Massó-Vallés, Daniel D; Giuntini, Fabio F; González-Larreategui, Íñigo Í; Kaur, Jastrinjan J; Casacuberta-Serra, Sílvia S; Jauset, Toni T; Martínez-Martín, Sandra S; Martín-Fernández, Génesis G; Serrano Del Pozo, Erika E; Foradada, Laia L; Grueso, Judit J; Nonell, Lara L; Beaulieu, Marie-Eve ME; Whitfield, Jonathan R JR; Soucek, Laura L

Publication Date: 2023-04-06

Variant appearance in text: TP53: L145R

PubMed Link: 37024284

Variant Present in the following documents:

• Main text
• 303.pdf

View BVdb publication page

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Efficacy and clinicogenomic correlates of response to immune checkpoint inhibitors alone or with chemotherapy in non-small cell lung cancer.

Nature Communications

Hong, Lingzhi L; Aminu, Muhammad M; Li, Shenduo S; Lu, Xuetao X; Petranovic, Milena M; Saad, Maliazurina B MB; Chen, Pingjun P; Qin, Kang K; Varghese, Susan S; Rinsurongkawong, Waree W; Rinsurongkawong, Vadeerat V; Spelman, Amy A; Elamin, Yasir Y YY; Negrao, Marcelo V MV; Skoulidis, Ferdinandos F; Gay, Carl M CM; Cascone, Tina T; Gandhi, Saumil J SJ; Lin, Steven H SH; Lee, Percy P PP; Carter, Brett W BW; Wu, Carol C CC; Antonoff, Mara B MB; Sepesi, Boris B; Lewis, Jeff J; Gibbons, Don L DL; Vaporciyan, Ara A AA; Le, Xiuning X; Jack Lee, J J; Roy-Chowdhuri, Sinchita S; Routbort, Mark J MJ; Gainor, Justin F JF; Heymach, John V JV; Lou, Yanyan Y; Wu, Jia J; Zhang, Jianjun J; Vokes, Natalie I NI

Publication Date: 2023-02-08

Variant appearance in text: TP53: 434T>G; L145R

PubMed Link: 36755027

Variant Present in the following documents:

• 41467_2023_36328_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Significance of logistic regression scoring model based on natural killer cell-mediated cytotoxic pathway in the diagnosis of colon cancer.

Frontiers In Immunology

Ye, Zhen Z; Zhang, Huanhuan H; Liang, Jianwei J; Yi, Shuying S; Zhan, Xianquan X

Publication Date: 2023

Variant appearance in text: TP53: L145R

PubMed Link: 36742322

Variant Present in the following documents:

• Table_8.xlsx, sheet 1

View BVdb publication page

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Exploring prognostic indicators in the pathological images of ovarian cancer based on a deep survival network.

Frontiers In Genetics

Wu, Meixuan M; Zhu, Chengguang C; Yang, Jiani J; Cheng, Shanshan S; Yang, Xiaokang X; Gu, Sijia S; Xu, Shilin S; Wu, Yongsong Y; Shen, Wei W; Huang, Shan S; Wang, Yu Y

Publication Date: 2022

Variant appearance in text: TP53: 434T>G; Leu145Arg

PubMed Link: 36685892

Variant Present in the following documents:

• Table3.xlsx, sheet 1

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: TP53: 434T>G; L145R

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 2

View BVdb publication page

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A sex-informed approach to improve the personalised decision making process in myelodysplastic syndromes: a multicentre, observational cohort study.

The Lancet. Haematology

,

Publication Date: 2022-11-24

Variant appearance in text: TP53: 434T>G

PubMed Link: 36436542

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: TP53: L145R

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: p53: 434T>G

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

View BVdb publication page

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Pepper Alkaloid Piperine Increases Radiation Sensitivity of Cancer Cells from Glioblastoma and Hypopharynx In Vitro.

International Journal Of Molecular Sciences

Diehl, Sascha S; Hildebrandt, Guido G; Manda, Katrin K

Publication Date: 2022-08-01

Variant appearance in text: p53: L145R

PubMed Link: 35955682

Variant Present in the following documents:

• Main text
• ijms-23-08548.pdf

View BVdb publication page

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Landscape of somatic alterations in large-scale solid tumors from an Asian population.

Nature Communications

Wu, Liqun L; Yao, Herui H; Chen, Hui H; Wang, Aodi A; Guo, Kun K; Gou, Wenli W; Yu, Yanfei Y; Li, Xiang X; Yao, Ming M; Yuan, Shaohua S; Pang, Fei F; Hu, Jinwei J; Chen, Lijuan L; Liu, Wenjin W; Yao, Jicheng J; Zhang, Shuirong S; Dong, Xiaowei X; Wang, Weifeng W; Hu, Jing J; Ling, Qi Q; Ding, Songming S; Wei, Yan Y; Li, Qiang Q; Cao, Weichun W; Wang, Shuang S; Di, Yang Y; Feng, Feiling F; Zhao, Gang G; Zhang, Jian J; Huang, Ling L; Xu, Jia J; Yan, Wangjun W; Tong, Zhongsheng Z; Jiang, Da D; Ji, Tao T; Li, Qiao Q; Xu, Ling L; He, Huiying H; Shang, Liang L; Liu, Jin J; Wang, Kefeng K; Wu, Duoguang D; Shen, Jingnan J; Liu, Ye Y; Zhang, Ting T; Liang, Chaojie C; Wang, Yusheng Y; Shang, Yanhong Y; Guo, Jianji J; Liang, Guanbiao G; Xu, Shifeng S; Liu, Junfeng J; Wang, Kai K; Wang, Minghui M

Publication Date: 2022-07-23

Variant appearance in text: TP53: L145R

PubMed Link: 35871175

Variant Present in the following documents:

• 41467_2022_31780_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis.

Nature Genetics

Kar, Siddhartha P SP; Quiros, Pedro M PM; Gu, Muxin M; Jiang, Tao T; Mitchell, Jonathan J; Langdon, Ryan R; Iyer, Vivek V; Barcena, Clea C; Vijayabaskar, M S MS; Fabre, Margarete A MA; Carter, Paul P; Petrovski, Slavé S; Burgess, Stephen S; Vassiliou, George S GS

Publication Date: 2022-08

Variant appearance in text: TP53: L145R

PubMed Link: 35835912

Variant Present in the following documents:

• 41588_2022_1121_MOESM3_ESM.xlsx, sheet 3

View BVdb publication page

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Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications

Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A

Publication Date: 2022-07-13

Variant appearance in text: TP53: 434T>G

PubMed Link: 35831314

Variant Present in the following documents:

• 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: TP53: L145R

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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Pathophysiologic and clinical implications of molecular profiles resultant from deletion 5q.

Ebiomedicine

Adema, Vera V; Palomo, Laura L; Walter, Wencke W; Mallo, Mar M; Hutter, Stephan S; La Framboise, Thomas T; Arenillas, Leonor L; Meggendorfer, Manja M; Radivoyevitch, Tomas T; Xicoy, Blanca B; Pellagatti, Andrea A; Haferlach, Claudia C; Boultwood, Jacqueline J; Kern, Wolfgang W; Visconte, Valeria V; Sekeres, Mikkael M; Barnard, John J; Haferlach, Torsten T; Solé, Francesc F; Maciejewski, Jaroslaw P JP

Publication Date: 2022-06

Variant appearance in text: TP53: 434T>G; Leu145Arg

PubMed Link: 35617825

Variant Present in the following documents:

• mmc3.xlsx, sheet 1

View BVdb publication page

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Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways.

Nature Communications

Zhang, Yiqun Y; Chen, Fengju F; Chandrashekar, Darshan S DS; Varambally, Sooryanarayana S; Creighton, Chad J CJ

Publication Date: 2022-05-13

Variant appearance in text: p53: L145R

PubMed Link: 35562349

Variant Present in the following documents:

• 41467_2022_30342_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Pure erythroid leukemia is characterized by biallelic TP53 inactivation and abnormal p53 expression patterns in de novo and secondary cases.

Haematologica

Fang, Hong H; Wang, Sa A SA; Khoury, Joseph D JD; El Hussein, Siba S; Kim, Do Hwan DH; Tashakori, Mehrnoosh M; Tang, Zhenya Z; Li, Shaoying S; Hu, Zhihong Z; Jelloul, Fatima Zahra FZ; Patel, Keyur P KP; McDonnell, Timothy J TJ; Kadia, Tapan T; Medeiros, L Jeffrey LJ; Wang, Wei W

Publication Date: 2022-09-01

Variant appearance in text: p53: 434T>G

PubMed Link: 35511670

Variant Present in the following documents:

• 1072232.pdf

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: TP53: 434T>G; L145R

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: TP53: 434T>G; Leu145Arg

PubMed Link: 35031014

Variant Present in the following documents:

• 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: TP53: 434T>G; Leu145Arg

PubMed Link: 35031014

Variant Present in the following documents:

• 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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eIF5A-Independent Role of DHPS in p21CIP1 and Cell Fate Regulation.

International Journal Of Molecular Sciences

Becker, Andrew E AE; Wu, Pui-Kei PK; Park, Jong-In JI

Publication Date: 2021-12-07

Variant appearance in text: TP53: L145R

PubMed Link: 34947982

Variant Present in the following documents:

• Main text

View BVdb publication page

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Altered Expression of Shorter p53 Family Isoforms Can Impact Melanoma Aggressiveness.

Cancers

Tadijan, Ana A; Precazzini, Francesca F; Hanžić, Nikolina N; Radić, Martina M; Gavioli, Nicolò N; Vlašić, Ignacija I; Ozretić, Petar P; Pinto, Lia L; Škreblin, Lidija L; Barban, Giulia G; Slade, Neda N; Ciribilli, Yari Y

Publication Date: 2021-10-18

Variant appearance in text: p53: L145R

PubMed Link: 34680379

Variant Present in the following documents:

• cancers-13-05231.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: TP53: L145R

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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IER2-induced senescence drives melanoma invasion through osteopontin.

Oncogene

Kyjacova, Lenka L; Saup, Rafael R; Rönsch, Kerstin K; Wallbaum, Sabine S; Dukowic-Schulze, Stefanie S; Foss, Amelia A; Scherer, Sandra D SD; Rothley, Melanie M; Neeb, Antje A; Grau, Nicole N; Thiele, Wilko W; Thaler, Sonja S; Cremers, Natascha N; Sticht, Carsten C; Gretz, Norbert N; Garvalov, Boyan K BK; Utikal, Jochen J; Sleeman, Jonathan P JP

Publication Date: 2021-11

Variant appearance in text: p53: L145R

PubMed Link: 34611309

Variant Present in the following documents:

• Main text

View BVdb publication page

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Acquisition of aneuploidy drives mutant p53-associated gain-of-function phenotypes.

Nature Communications

Redman-Rivera, Lindsay N LN; Shaver, Timothy M TM; Jin, Hailing H; Marshall, Clayton B CB; Schafer, Johanna M JM; Sheng, Quanhu Q; Hongo, Rachel A RA; Beckermann, Kathryn E KE; Wheeler, Ferrin C FC; Lehmann, Brian D BD; Pietenpol, Jennifer A JA

Publication Date: 2021-08-31

Variant appearance in text: TP53: L145R

PubMed Link: 34465782

Variant Present in the following documents:

• 41467_2021_25359_MOESM5_ESM.xlsx, sheet 33

View BVdb publication page

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The landscape of driver mutations in cutaneous squamous cell carcinoma.

Npj Genomic Medicine

Chang, Darwin D; Shain, A Hunter AH

Publication Date: 2021-07-16

Variant appearance in text: TP53: L145R

PubMed Link: 34272401

Variant Present in the following documents:

• 41525_2021_226_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports

Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM

Publication Date: 2021-07-12

Variant appearance in text: TP53: 434T>G; L145R

PubMed Link: 34253785

Variant Present in the following documents:

• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 10

View BVdb publication page

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Improvement of Neoantigen Identification Through Convolution Neural Network.

Frontiers In Immunology

Hao, Qing Q; Wei, Ping P; Shu, Yang Y; Zhang, Yi-Guan YG; Xu, Heng H; Zhao, Jun-Ning JN

Publication Date: 2021

Variant appearance in text: TP53: L145R

PubMed Link: 34113354

Variant Present in the following documents:

• Table_1.xlsx, sheet 6
• Table_1.xlsx, sheet 20

View BVdb publication page

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Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications

Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L

Publication Date: 2021-04-19

Variant appearance in text: TP53: L145R

PubMed Link: 33875650

Variant Present in the following documents:

• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Melanoma subpopulations that rapidly escape MAPK pathway inhibition incur DNA damage and rely on stress signalling.

Nature Communications

Yang, Chen C; Tian, Chengzhe C; Hoffman, Timothy E TE; Jacobsen, Nicole K NK; Spencer, Sabrina L SL

Publication Date: 2021-03-19

Variant appearance in text: TP53: L145R

PubMed Link: 33741929

Variant Present in the following documents:

• 41467_2021_21549_MOESM1_ESM.pdf

View BVdb publication page

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MITF reprograms the extracellular matrix and focal adhesion in melanoma.

Elife

Dilshat, Ramile R; Fock, Valerie V; Kenny, Colin C; Gerritsen, Ilse I; Lasseur, Romain Maurice Jacques RMJ; Travnickova, Jana J; Eichhoff, Ossia M OM; Cerny, Philipp P; Möller, Katrin K; Sigurbjörnsdóttir, Sara S; Kirty, Kritika K; Einarsdottir, Berglind Ósk BÓ; Cheng, Phil F PF; Levesque, Mitchell M; Cornell, Robert A RA; Patton, E Elizabeth EE; Larue, Lionel L; de Tayrac, Marie M; Magnúsdóttir, Erna E; Ögmundsdóttir, Margrét Helga MH; Steingrimsson, Eirikur E

Publication Date: 2021-01-13

Variant appearance in text: p53: L145R

PubMed Link: 33438577

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: TP53: 434T>G; L145R

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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STAT3 and p53: Dual Target for Cancer Therapy.

Biomedicines

Pham, Thu-Huyen TH; Park, Hyo-Min HM; Kim, Jinju J; Hong, Jin Tae JT; Yoon, Do-Young DY

Publication Date: 2020-12-21

Variant appearance in text: p53: L145R

PubMed Link: 33371351

Variant Present in the following documents:

• Main text
• biomedicines-08-00637.pdf

View BVdb publication page

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Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine

Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS

Publication Date: 2021-01

Variant appearance in text: TP53: L145R

PubMed Link: 33314633

Variant Present in the following documents:

• CAM4-10-53-s003.xlsx, sheet 1

View BVdb publication page

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Clinical advantage of targeted sequencing for unbiased tumor mutational burden estimation in samples with low tumor purity.

Journal For Immunotherapy Of Cancer

Hong, Tae Hee TH; Cha, Hongui H; Shim, Joon Ho JH; Lee, Boram B; Chung, Jongsuk J; Lee, Chung C; Kim, Nayoung K D NKD; Choi, Yoon-La YL; Hwang, Soohyun S; Lee, Yoomi Y; Park, Sehhoon S; Jung, Hyun Ae HA; Kim, Ji-Yeon JY; Park, Yeon Hee YH; Sun, Jong-Mu JM; Ahn, Jin Seok JS; Ahn, Myung-Ju MJ; Park, Keunchil K; Lee, Se-Hoon SH; Park, Woong-Yang WY

Publication Date: 2020-10

Variant appearance in text: TP53: L145R

PubMed Link: 33077514

Variant Present in the following documents:

• jitc-2020-001199supp002.pdf

View BVdb publication page

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Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.

Nature Communications

Pandey, Akhilesh A; Stawiski, Eric W EW; Durinck, Steffen S; Gowda, Harsha H; Goldstein, Leonard D LD; Barbhuiya, Mustafa A MA; Schröder, Markus S MS; Sreenivasamurthy, Sreelakshmi K SK; Kim, Sun-Whe SW; Phalke, Sameer S; Suryamohan, Kushal K; Lee, Kayla K; Chakraborty, Papia P; Kode, Vasumathi V; Shi, Xiaoshan X; Chatterjee, Aditi A; Datta, Keshava K; Khan, Aafaque A AA; Subbannayya, Tejaswini T; Wang, Jing J; Chaudhuri, Subhra S; Gupta, Sanjiv S; Shrivastav, Braj Raj BR; Jaiswal, Bijay S BS; Poojary, Satish S SS; Bhunia, Shushruta S; Garcia, Patricia P; Bizama, Carolina C; Rosa, Lorena L; Kwon, Wooil W; Kim, Hongbeom H; Han, Youngmin Y; Yadav, Thakur Deen TD; Ramprasad, Vedam L VL; Chaudhuri, Amitabha A; Modrusan, Zora Z; Roa, Juan Carlos JC; Tiwari, Pramod Kumar PK; Jang, Jin-Young JY; Seshagiri, Somasekar S

Publication Date: 2020-08-24

Variant appearance in text: TP53: L145R

PubMed Link: 32839463

Variant Present in the following documents:

• 41467_2020_17880_MOESM5_ESM.xlsx, sheet 1
• 41467_2020_17880_MOESM13_ESM.xlsx, sheet 1

View BVdb publication page

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mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.

Cell Reports

Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM

Publication Date: 2020-06-23

Variant appearance in text: TP53: L145R

PubMed Link: 32579932

Variant Present in the following documents:

• mmc5.xlsx, sheet 3

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: TP53: L145R

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: TP53: 434T>G; L145R

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution.

Journal For Immunotherapy Of Cancer

Florou, Vaia V; Rosenberg, Andrew E AE; Wieder, Eric E; Komanduri, Krishna V KV; Kolonias, Despina D; Uduman, Mohamed M; Castle, John C JC; Buell, Jennifer S JS; Trent, Jonathan C JC; Wilky, Breelyn A BA

Publication Date: 2019-08-08

Variant appearance in text: TP53: L145R

PubMed Link: 31395100

Variant Present in the following documents:

• Main text
• 40425_2019_Article_689.pdf

View BVdb publication page

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Integrated multi-omics analysis of genomics, epigenomics, and transcriptomics in ovarian carcinoma.

Aging

Zheng, Mingjun M; Hu, Yuexin Y; Gou, Rui R; Wang, Jing J; Nie, Xin X; Li, Xiao X; Liu, Qing Q; Liu, Juanjuan J; Lin, Bei B

Publication Date: 2019-06-29

Variant appearance in text: TP53: 434T>G

PubMed Link: 31257224

Variant Present in the following documents:

• aging-11-102047-s002.xlsx, sheet 13
• aging-11-102047-s002.xlsx, sheet 11
• aging-11-102047-s002.xlsx, sheet 12

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The lncRNA SLNCR Recruits the Androgen Receptor to EGR1-Bound Genes in Melanoma and Inhibits Expression of Tumor Suppressor p21.

Cell Reports

Schmidt, Karyn K; Carroll, Johanna S JS; Yee, Elaine E; Thomas, Dolly D DD; Wert-Lamas, Leon L; Neier, Steven C SC; Sheynkman, Gloria G; Ritz, Justin J; Novina, Carl D CD

Publication Date: 2019-05-21

Variant appearance in text: p53: L145R

PubMed Link: 31116991

Variant Present in the following documents:

• Main text

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: TP53: L145R

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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Thymine DNA glycosylase as a novel target for melanoma.

Oncogene

Mancuso, Pietro P; Tricarico, Rossella R; Bhattacharjee, Vikram V; Cosentino, Laura L; Kadariya, Yuwaraj Y; Jelinek, Jaroslav J; Nicolas, Emmanuelle E; Einarson, Margret M; Beeharry, Neil N; Devarajan, Karthik K; Katz, Richard A RA; Dorjsuren, Dorjbal G DG; Sun, Hongmao H; Simeonov, Anton A; Giordano, Antonio A; Testa, Joseph R JR; Davidson, Guillaume G; Davidson, Irwin I; Larue, Lionel L; Sobol, Robert W RW; Yen, Timothy J TJ; Bellacosa, Alfonso A

Publication Date: 2019-05

Variant appearance in text: TP53: L145R

PubMed Link: 30674989

Variant Present in the following documents:

• Main text
• 41388_2018_Article_640.pdf

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Erythropoietin inhibits chemotherapy-induced cell death and promotes a senescence-like state in leukemia cells.

Cell Death & Disease

Pham, Thuc-Nghi Duc TD; Ma, Weili W; Miller, David D; Kazakova, Lidia L; Benchimol, Samuel S

Publication Date: 2019-01-08

Variant appearance in text: p53: L145R

PubMed Link: 30622244

Variant Present in the following documents:

• Main text

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TNF-alpha and metalloproteases as key players in melanoma cells aggressiveness.

Journal Of Experimental & Clinical Cancer Research : Cr

Rossi, Stefania S; Cordella, Martina M; Tabolacci, Claudio C; Nassa, Giovanni G; D'Arcangelo, Daniela D; Senatore, Cinzia C; Pagnotto, Paolo P; Magliozzi, Roberta R; Salvati, Annamaria A; Weisz, Alessandro A; Facchiano, Antonio A; Facchiano, Francesco F

Publication Date: 2018-12-28

Variant appearance in text: TP53: L145R

PubMed Link: 30591049

Variant Present in the following documents:

• Main text
• 13046_2018_Article_982.pdf

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Melanoma cells resistant towards MAPK inhibitors exhibit reduced TAp73 expression mediating enhanced sensitivity to platinum-based drugs.

Cell Death & Disease

Makino, Elena E; Gutmann, Vanessa V; Kosnopfel, Corinna C; Niessner, Heike H; Forschner, Andrea A; Garbe, Claus C; Sinnberg, Tobias T; Schittek, Birgit B

Publication Date: 2018-09-11

Variant appearance in text: TP53: L145R

PubMed Link: 30206212

Variant Present in the following documents:

• Main text
• 41419_2018_Article_952.pdf

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The prognostic effects of somatic mutations in ER-positive breast cancer.

Nature Communications

Griffith, Obi L OL; Spies, Nicholas C NC; Anurag, Meenakshi M; Griffith, Malachi M; Luo, Jingqin J; Tu, Dongsheng D; Yeo, Belinda B; Kunisaki, Jason J; Miller, Christopher A CA; Krysiak, Kilannin K; Hundal, Jasreet J; Ainscough, Benjamin J BJ; Skidmore, Zachary L ZL; Campbell, Katie K; Kumar, Runjun R; Fronick, Catrina C; Cook, Lisa L; Snider, Jacqueline E JE; Davies, Sherri S; Kavuri, Shyam M SM; Chang, Eric C EC; Magrini, Vincent V; Larson, David E DE; Fulton, Robert S RS; Liu, Shuzhen S; Leung, Samuel S; Voduc, David D; Bose, Ron R; Dowsett, Mitch M; Wilson, Richard K RK; Nielsen, Torsten O TO; Mardis, Elaine R ER; Ellis, Matthew J MJ

Publication Date: 2018-09-04

Variant appearance in text: TP53: L145R

PubMed Link: 30181556

Variant Present in the following documents:

• 41467_2018_5914_MOESM6_ESM.xlsx, sheet 5
• 41467_2018_5914_MOESM6_ESM.xlsx, sheet 6
• 41467_2018_5914_MOESM6_ESM.xlsx, sheet 12
• 41467_2018_5914_MOESM6_ESM.xlsx, sheet 9
• 41467_2018_5914_MOESM6_ESM.xlsx, sheet 10

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Coupling of the polyamine and iron metabolism pathways in the regulation of proliferation: Mechanistic links to alterations in key polyamine biosynthetic and catabolic enzymes.

Biochimica Et Biophysica Acta. Molecular Basis Of Disease

Lane, Darius J R DJR; Bae, Dong-Hun DH; Siafakas, Aritee R AR; Suryo Rahmanto, Yohan Y; Al-Akra, Lina L; Jansson, Patric J PJ; Casero, Robert A RA; Richardson, Des R DR

Publication Date: 2018-09

Variant appearance in text: p53: L145R

PubMed Link: 29777905

Variant Present in the following documents:

• Main text

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Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.

The Journal Of Pathology

Temko, Daniel D; Van Gool, Inge C IC; Rayner, Emily E; Glaire, Mark M; Makino, Seiko S; Brown, Matthew M; Chegwidden, Laura L; Palles, Claire C; Depreeuw, Jeroen J; Beggs, Andrew A; Stathopoulou, Chaido C; Mason, John J; Baker, Ann-Marie AM; Williams, Marc M; Cerundolo, Vincenzo V; Rei, Margarida M; Taylor, Jenny C JC; Schuh, Anna A; Ahmed, Ahmed A; Amant, Frédéric F; Lambrechts, Diether D; Smit, Vincent Thbm VT; Bosse, Tjalling T; Graham, Trevor A TA; Church, David N DN; Tomlinson, Ian I

Publication Date: 2018-07

Variant appearance in text: TP53: 434T>G; L145R

PubMed Link: 29604063

Variant Present in the following documents:

• PATH-245-283-s022.xlsx, sheet 1

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Methotrexate sensitizes drug-resistant metastatic melanoma cells to BRAF V600E inhibitors dabrafenib and encorafenib.

Oncotarget

Ross, Kayleigh C KC; Chin, Kevin F KF; Kim, Daehwan D; Marion, Christopher D CD; Yen, Timothy J TJ; Bhattacharjee, Vikram V

Publication Date: 2018-03-02

Variant appearance in text: TP53: L145R

PubMed Link: 29568360

Variant Present in the following documents:

• Main text
• oncotarget-09-13324.pdf

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Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential.

Nature Communications

Wong, Terrence N TN; Miller, Christopher A CA; Jotte, Matthew R M MRM; Bagegni, Nusayba N; Baty, Jack D JD; Schmidt, Amy P AP; Cashen, Amanda F AF; Duncavage, Eric J EJ; Helton, Nichole M NM; Fiala, Mark M; Fulton, Robert S RS; Heath, Sharon E SE; Janke, Megan M; Luber, Kierstin K; Westervelt, Peter P; Vij, Ravi R; DiPersio, John F JF; Welch, John S JS; Graubert, Timothy A TA; Walter, Matthew J MJ; Ley, Timothy J TJ; Link, Daniel C DC

Publication Date: 2018-01-31

Variant appearance in text: TP53: L145R

PubMed Link: 29386642

Variant Present in the following documents:

• 41467_2018_2858_MOESM5_ESM.xlsx, sheet 1

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Mutations in the DNA methylation pathway and number of driver mutations predict response to azacitidine in myelodysplastic syndromes.

Oncotarget

Cedena, M Teresa MT; Rapado, Inmaculada I; Santos-Lozano, Alejandro A; Ayala, Rosa R; Onecha, Esther E; Abaigar, María M; Such, Esperanza E; Ramos, Fernando F; Cervera, José J; Díez-Campelo, María M; Sanz, Guillermo G; Rivas, Jesús Hernández JH; Lucía, Alejandro A; Martínez-López, Joaquin J

Publication Date: 2017-12-05

Variant appearance in text: TP53: 434T>G; Leu145Arg

PubMed Link: 29291002

Variant Present in the following documents:

• oncotarget-08-106948-s002.xls, sheet 1

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Cell Dispersal Influences Tumor Heterogeneity and Introduces a Bias in NGS Data Interpretation.

Scientific Reports

Pongor, Lőrinc L; Harami-Papp, Hajnalka H; Méhes, Előd E; Czirók, András A; Győrffy, Balázs B

Publication Date: 2017-08-04

Variant appearance in text: TP53: 434T>G

PubMed Link: 28779157

Variant Present in the following documents:

• 41598_2017_7487_MOESM5_ESM.xls, sheet 5
• 41598_2017_7487_MOESM5_ESM.xls, sheet 4
• 41598_2017_7487_MOESM6_ESM.xls, sheet 2

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