TP53 c.398T>C ;(p.M133T)

Variant ID: 17-7578532-A-G

NM_000546.5(TP53):c.398T>C;(p.M133T)

This variant was identified in 56 publications

View GRCh38 version.




Publications:


Rewired m6A epitranscriptomic networks link mutant p53 to neoplastic transformation.

Nature Communications
Xu, An A; Liu, Mo M; Huang, Mo-Fan MF; Zhang, Yang Y; Hu, Ruifeng R; Gingold, Julian A JA; Liu, Ying Y; Zhu, Dandan D; Chien, Chian-Shiu CS; Wang, Wei-Chen WC; Liao, Zian Z; Yuan, Fei F; Hsu, Chih-Wei CW; Tu, Jian J; Yu, Yao Y; Rosen, Taylor T; Xiong, Feng F; Jia, Peilin P; Yang, Yi-Ping YP; Bazer, Danielle A DA; Chen, Ya-Wen YW; Li, Wenbo W; Huff, Chad D CD; Zhu, Jay-Jiguang JJ; Aguilo, Francesca F; Chiou, Shih-Hwa SH; Boles, Nathan C NC; Lai, Chien-Chen CC; Hung, Mien-Chie MC; Zhao, Zhongming Z; Van Nostrand, Eric L EL; Zhao, Ruiying R; Lee, Dung-Fang DF
Publication Date: 2023-03-27

Variant appearance in text: p53: M133T
PubMed Link: 36973285
Variant Present in the following documents:
  • Main text
  • 41467_2023_Article_37398.pdf
View BVdb publication page



Evaluation of AlphaFold structure-based protein stability prediction on missense variations in cancer.

Frontiers In Genetics
Keskin Karakoyun, Hilal H; Yüksel, Şirin K ŞK; Amanoglu, Ilayda I; Naserikhojasteh, Lara L; Yeşilyurt, Ahmet A; Yakıcıer, Cengiz C; Timuçin, Emel E; Akyerli, Cemaliye B CB
Publication Date: 2023

Variant appearance in text: TP53: M133T
PubMed Link: 36896237
Variant Present in the following documents:
  • Table1.xlsx, sheet 1
View BVdb publication page



Integration of deep learning with Ramachandran plot molecular dynamics simulation for genetic variant classification.

Iscience
Tam, Benjamin B; Qin, Zixin Z; Zhao, Bojin B; Wang, San Ming SM; Lei, Chon Lok CL
Publication Date: 2023-03-17

Variant appearance in text: TP53: 398T>C; M133T
PubMed Link: 36879825
Variant Present in the following documents:
  • mmc2.xlsx, sheet 1
  • mmc3.xlsx, sheet 1
  • mmc4.xlsx, sheet 1
View BVdb publication page



Network expansion of genetic associations defines a pleiotropy map of human cell biology.

Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Publication Date: 2023-02-23

Variant appearance in text: TP53: 398T>C; Met133Thr
PubMed Link: 36823319
Variant Present in the following documents:
  • 41588_2023_1327_MOESM4_ESM.xlsx, sheet 6
View BVdb publication page



Application of Genomic Sequencing to Refine Patient Stratification for Adjuvant Therapy in Renal Cell Carcinoma.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Vasudev, Naveen S NS; Scelo, Ghislaine G; Glennon, Kate I KI; Wilson, Michelle M; Letourneau, Louis L; Eveleigh, Robert R; Nourbehesht, Nazanin N; Arseneault, Madeleine M; Paccard, Antoine A; Egevad, Lars L; Viksna, Juris J; Celms, Edgars E; Jackson, Sharon M SM; Abedi-Ardekani, Behnoush B; Warren, Anne Y AY; Selby, Peter J PJ; Trainor, Sebastian S; Kimuli, Michael M; Cartledge, Jon J; Soomro, Naeem N; Adeyoju, Adebanji A; Patel, Poulam M PM; Wozniak, Magdalena B MB; Holcatova, Ivana I; Brisuda, Antonin A; Janout, Vladimir V; Chanudet, Estelle E; Zaridze, David D; Moukeria, Anush A; Shangina, Oxana O; Foretova, Lenka L; Navratilova, Marie M; Mates, Dana D; Jinga, Viorel V; Bogdanovic, Ljiljana L; Kovacevic, Bozidar B; Cambon-Thomsen, Anne A; Bourque, Guillaume G; Brazma, Alvis A; Tost, Jörg J; Brennan, Paul P; Lathrop, Mark M; Riazalhosseini, Yasser Y; Banks, Rosamonde E RE
Publication Date: 2023-02-23

Variant appearance in text: TP53: 398T>C; Met133Thr; rs28934873
PubMed Link: 36815791
Variant Present in the following documents:
  • ccr-22-1936_supplementary_table_s2_suppts2.xlsx, sheet 1
View BVdb publication page



ESR1 gene amplification and MAP3K mutations are selected during adjuvant endocrine therapies in relapsing Hormone Receptor-positive, HER2-negative breast cancer (HR+ HER2- BC).

Plos Genetics
Ferrando, Lorenzo L; Vingiani, Andrea A; Garuti, Anna A; Vernieri, Claudio C; Belfiore, Antonino A; Agnelli, Luca L; Dagrada, Gianpaolo G; Ivanoiu, Diana D; Bonizzi, Giuseppina G; Munzone, Elisabetta E; Lippolis, Luana L; Dameri, Martina M; Ravera, Francesco F; Colleoni, Marco M; Viale, Giuseppe G; Magnani, Luca L; Ballestrero, Alberto A; Zoppoli, Gabriele G; Pruneri, Giancarlo G
Publication Date: 2023-01-03

Variant appearance in text: rs28934873
PubMed Link: 36595552
Variant Present in the following documents:
  • pgen.1010563.s004.xlsx, sheet 1
View BVdb publication page



Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: TP53: M133T
PubMed Link: 36561320
Variant Present in the following documents:
  • Table3.xlsx, sheet 1
  • Table2.xlsx, sheet 7
View BVdb publication page



Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics
Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q
Publication Date: 2022-11-04

Variant appearance in text: TP53: 398T>C; M133T
PubMed Link: 36333792
Variant Present in the following documents:
  • 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience
Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X
Publication Date: 2022-09-16

Variant appearance in text: p53: 398T>C
PubMed Link: 36117989
Variant Present in the following documents:
  • mmc4.xlsx, sheet 1
View BVdb publication page



Landscape of somatic alterations in large-scale solid tumors from an Asian population.

Nature Communications
Wu, Liqun L; Yao, Herui H; Chen, Hui H; Wang, Aodi A; Guo, Kun K; Gou, Wenli W; Yu, Yanfei Y; Li, Xiang X; Yao, Ming M; Yuan, Shaohua S; Pang, Fei F; Hu, Jinwei J; Chen, Lijuan L; Liu, Wenjin W; Yao, Jicheng J; Zhang, Shuirong S; Dong, Xiaowei X; Wang, Weifeng W; Hu, Jing J; Ling, Qi Q; Ding, Songming S; Wei, Yan Y; Li, Qiang Q; Cao, Weichun W; Wang, Shuang S; Di, Yang Y; Feng, Feiling F; Zhao, Gang G; Zhang, Jian J; Huang, Ling L; Xu, Jia J; Yan, Wangjun W; Tong, Zhongsheng Z; Jiang, Da D; Ji, Tao T; Li, Qiao Q; Xu, Ling L; He, Huiying H; Shang, Liang L; Liu, Jin J; Wang, Kefeng K; Wu, Duoguang D; Shen, Jingnan J; Liu, Ye Y; Zhang, Ting T; Liang, Chaojie C; Wang, Yusheng Y; Shang, Yanhong Y; Guo, Jianji J; Liang, Guanbiao G; Xu, Shifeng S; Liu, Junfeng J; Wang, Kai K; Wang, Minghui M
Publication Date: 2022-07-23

Variant appearance in text: TP53: M133T
PubMed Link: 35871175
Variant Present in the following documents:
  • 41467_2022_31780_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: TP53: 398T>C; L133P
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



The genetic heterogeneity and drug resistance mechanisms of relapsed refractory multiple myeloma.

Nature Communications
Vo, Josh N JN; Wu, Yi-Mi YM; Mishler, Jeanmarie J; Hall, Sarah S; Mannan, Rahul R; Wang, Lisha L; Ning, Yu Y; Zhou, Jin J; Hopkins, Alexander C AC; Estill, James C JC; Chan, Wallace K B WKB; Yesil, Jennifer J; Cao, Xuhong X; Rao, Arvind A; Tsodikov, Alexander A; Talpaz, Moshe M; Cole, Craig E CE; Ye, Jing C JC; , ; Bergsagel, P Leif PL; Auclair, Daniel D; Cho, Hearn Jay HJ; Robinson, Dan R DR; Chinnaiyan, Arul M AM
Publication Date: 2022-06-29

Variant appearance in text: TP53: 398T>C; Met133Thr; rs28934873
PubMed Link: 35768438
Variant Present in the following documents:
  • 41467_2022_31430_MOESM4_ESM.xlsx, sheet 1
View BVdb publication page



Snail Promotes Cancer Cell Proliferation via Its Interaction with the BIRC3.

Biomolecules & Therapeutics
Rho, Seung Bae SB; Byun, Hyun-Jung HJ; Kim, Boh-Ram BR; Lee, Chang Hoon CH
Publication Date: 2022-07-01

Variant appearance in text: TP53: M133T
PubMed Link: 35711139
Variant Present in the following documents:
  • Main text
  • bt-30-4-380.pdf
View BVdb publication page



Targeting AKT and CK2 represents a novel therapeutic strategy for SMO constitutive activation-driven medulloblastoma.

Cns Neuroscience & Therapeutics
Yao, Yue-Liang YL; Wang, Yan-Xia YX; Yang, Fei-Cheng FC; Wang, Chuan C; Mao, Min M; Gai, Qu-Jing QJ; He, Jiang J; Qin, Yan Y; Yao, Xiao-Xue XX; Lan, Xi X; Zhu, Jiang J; Lu, Hui-Min HM; Zeng, Hui H; Yao, Xiao-Hong XH; Bian, Xiu-Wu XW; Wang, Yan Y
Publication Date: 2022-07

Variant appearance in text: p53: M133T
PubMed Link: 35419951
Variant Present in the following documents:
  • CNS-28-1033-s002.pdf
View BVdb publication page



Are transient protein-protein interactions more dispensable?

Plos Computational Biology
Ghadie, Mohamed Ali MA; Xia, Yu Y
Publication Date: 2022-04

Variant appearance in text: TP53: 398T>C; Met133Thr
PubMed Link: 35404956
Variant Present in the following documents:
  • pcbi.1010013.s002.xlsx, sheet 4
View BVdb publication page



Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications
Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L
Publication Date: 2022-03-10

Variant appearance in text: TP53: 398T>C; M133T
PubMed Link: 35273153
Variant Present in the following documents:
  • 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data Set: An International Agency for Research on Cancer TP53 Database Analysis.

Jama Oncology
Kratz, Christian P CP; Freycon, Claire C; Maxwell, Kara N KN; Nichols, Kim E KE; Schiffman, Joshua D JD; Evans, D Gareth DG; Achatz, Maria I MI; Savage, Sharon A SA; Weitzel, Jeffrey N JN; Garber, Judy E JE; Hainaut, Pierre P; Malkin, David D
Publication Date: 2021-10-28

Variant appearance in text: TP53: M133T
PubMed Link: 34709361
Variant Present in the following documents:
  • Main text
View BVdb publication page



Analysis of the Li-Fraumeni Spectrum Based on an International Germline TP53 Variant Data Set: An International Agency for Research on Cancer TP53 Database Analysis.

Jama Oncology
Kratz, Christian P CP; Freycon, Claire C; Maxwell, Kara N KN; Nichols, Kim E KE; Schiffman, Joshua D JD; Evans, D Gareth DG; Achatz, Maria I MI; Savage, Sharon A SA; Weitzel, Jeffrey N JN; Garber, Judy E JE; Hainaut, Pierre P; Malkin, David D
Publication Date: 2021-12-01

Variant appearance in text: TP53: M133T
PubMed Link: 34709361
Variant Present in the following documents:
  • Main text
View BVdb publication page



Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition.

Molecular & Cellular Proteomics : Mcp
Schmitt, Marisa M; Sinnberg, Tobias T; Bratl, Katrin K; Zittlau, Katharina K; Garbe, Claus C; Macek, Boris B; Nalpas, Nicolas C NC
Publication Date: 2021

Variant appearance in text: p53: M133T
PubMed Link: 34673281
Variant Present in the following documents:
  • mmc2.xlsx, sheet 4
  • mmc2.xlsx, sheet 6
View BVdb publication page



Proteogenomics Reveals Perturbed Signaling Networks in Malignant Melanoma Cells Resistant to BRAF Inhibition.

Molecular & Cellular Proteomics : Mcp
Schmitt, Marisa M; Sinnberg, Tobias T; Bratl, Katrin K; Zittlau, Katharina K; Garbe, Claus C; Macek, Boris B; Nalpas, Nicolas C NC
Publication Date: 2021-10-19

Variant appearance in text: p53: M133T
PubMed Link: 34673281
Variant Present in the following documents:
  • mmc2.xlsx, sheet 4
  • mmc2.xlsx, sheet 6
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: TP53: M133T
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



The landscape of driver mutations in cutaneous squamous cell carcinoma.

Npj Genomic Medicine
Chang, Darwin D; Shain, A Hunter AH
Publication Date: 2021-07-16

Variant appearance in text: TP53: M133T
PubMed Link: 34272401
Variant Present in the following documents:
  • 41525_2021_226_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports
Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM
Publication Date: 2021-07-12

Variant appearance in text: TP53: 398T>C; M133T
PubMed Link: 34253785
Variant Present in the following documents:
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 4
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 5
  • 41598_2021_93715_MOESM2_ESM.xlsx, sheet 7
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 6
  • 41598_2021_93715_MOESM2_ESM.xlsx, sheet 10
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 2
  • 41598_2021_93715_MOESM2_ESM.xlsx, sheet 9
View BVdb publication page



Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer
Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA
Publication Date: 2021-05

Variant appearance in text: TP53: 398T>C; M133T
PubMed Link: 33704917
Variant Present in the following documents:
  • TCA-12-1271-s003.xls, sheet 1
View BVdb publication page



Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications
Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q
Publication Date: 2021-01-04

Variant appearance in text: TP53: 398T>C; M133T
PubMed Link: 33397889
Variant Present in the following documents:
  • 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Post-radiation circulating tumor DNA as a prognostic factor in locally advanced esophageal squamous cell carcinoma.

Oncology Letters
Jia, Ru R; Zhao, Chuan-Hua CH; Li, Pan-Song PS; Liu, Rong-Rui RR; Zhang, Yun Y; Chen, Hai-E HE; Chang, Lian-Peng LP; Gong, Yu-Hua YH; Guan, Yan-Fang YF; Yi, Xin X; Xu, Jian-Ming JM
Publication Date: 2021-01

Variant appearance in text: TP53: 398T>C
PubMed Link: 33365079
Variant Present in the following documents:
  • Supplementary_Data3.xlsx, sheet 1
View BVdb publication page



Circulating tumour DNA in metastatic breast cancer to guide clinical trial enrolment and precision oncology: A cohort study.

Plos Medicine
Zivanovic Bujak, Andjelija A; Weng, Chen-Fang CF; Silva, Maria João MJ; Yeung, Miriam M; Lo, Louisa L; Ftouni, Sarah S; Litchfield, Cassandra C; Ko, Yi-An YA; Kuykhoven, Keilly K; Van Geelen, Courtney C; Chandrashekar, Sushma S; Dawson, Mark A MA; Loi, Sherene S; Wong, Stephen Q SQ; Dawson, Sarah-Jane SJ
Publication Date: 2020-10

Variant appearance in text: TP53: M133T
PubMed Link: 33001984
Variant Present in the following documents:
  • pmed.1003363.s013.xlsx, sheet 1
View BVdb publication page



Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports
Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA
Publication Date: 2020-09-21

Variant appearance in text: TP53: M133T
PubMed Link: 32958805
Variant Present in the following documents:
  • 41598_2020_72404_MOESM2_ESM.xlsx, sheet 2
View BVdb publication page



Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects.

Science Advances
Lee, Sangsin S; Ding, Ning N; Sun, Yidi Y; Yuan, Tanglong T; Li, Jing J; Yuan, Qichen Q; Liu, Lizhong L; Yang, Jie J; Wang, Qian Q; Kolomeisky, Anatoly B AB; Hilton, Isaac B IB; Zuo, Erwei E; Gao, Xue X
Publication Date: 2020-07

Variant appearance in text: TP53: 398T>C; Met133Thr
PubMed Link: 32832622
Variant Present in the following documents:
  • aba1773_Data_file_S1.xlsx, sheet 2
View BVdb publication page



Defining relative mutational difficulty to understand cancer formation.

Cell Discovery
Shan, Lin L; Yu, Jiao J; He, Zhengjin Z; Chen, Shishuang S; Liu, Mingxian M; Ding, Hongyu H; Xu, Liang L; Zhao, Jie J; Yang, Ailing A; Jiang, Hai H
Publication Date: 2020

Variant appearance in text: p53: M133T
PubMed Link: 32704382
Variant Present in the following documents:
  • 41421_2020_177_MOESM5_ESM.xlsx, sheet 1
  • 41421_2020_177_MOESM6_ESM.xlsx, sheet 1
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: TP53: M133T
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery.

Oncotarget
Ye, Ling F LF; Reznik, Eduard E; Korn, Joshua M JM; Lin, Fallon F; Yang, Guizhi G; Malesky, Kimberly K; Gao, Hui H; Loo, Alice A; Pagliarini, Raymond R; Mikkelsen, Tom T; Lo, Donald C DC; deCarvalho, Ana C AC; Stockwell, Brent R BR
Publication Date: 2020-01-28

Variant appearance in text: p53: M133T
PubMed Link: 32064048
Variant Present in the following documents:
  • Main text
View BVdb publication page



Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma.

Cells
Flynt, Erin E; Bisht, Kamlesh K; Sridharan, Vinidhra V; Ortiz, María M; Towfic, Fadi F; Thakurta, Anjan A
Publication Date: 2020-01-24

Variant appearance in text: TP53: M133T
PubMed Link: 31991614
Variant Present in the following documents:
  • Main text
  • cells-09-00287.pdf
View BVdb publication page



p53-responsive TLR8 SNP enhances human innate immune response to respiratory syncytial virus.

The Journal Of Clinical Investigation
Menendez, Daniel D; Snipe, Joyce J; Marzec, Jacqui J; Innes, Cynthia L CL; Polack, Fernando P FP; Caballero, Mauricio T MT; Schurman, Shepherd H SH; Kleeberger, Steven R SR; Resnick, Michael A MA
Publication Date: 2019-11-01

Variant appearance in text: p53: M133T
PubMed Link: 31430261
Variant Present in the following documents:
  • Main text
View BVdb publication page



Estimating dispensable content in the human interactome.

Nature Communications
Ghadie, Mohamed M; Xia, Yu Y
Publication Date: 2019-07-19

Variant appearance in text: TP53: 398T>C; Met133Thr
PubMed Link: 31324802
Variant Present in the following documents:
  • 41467_2019_11180_MOESM6_ESM.xlsx, sheet 4
  • 41467_2019_11180_MOESM8_ESM.xlsx, sheet 4
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: TP53: M133T
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.

Cold Spring Harbor Molecular Case Studies
Quinn, Emily A EA; Maciaszek, Jamie L JL; Pinto, Emilia M EM; Phillips, Aaron H AH; Berdy, David D; Khandwala, Mohammad M; Upadhyaya, Santhosh A SA; Zambetti, Gerard P GP; Kriwacki, Richard W RW; Ellison, David W DW; Nichols, Kim E KE; Kesserwan, Chimene C
Publication Date: 2019-08

Variant appearance in text: TP53: 398T>C; M133T
PubMed Link: 30886117
Variant Present in the following documents:
  • supp_mcs.a003921_Supplemental_Table_1a.xlsx, sheet 1
  • supp_mcs.a003921_Supplemental_Table_2.xlsx, sheet 1
View BVdb publication page



Patterns of genomic evolution in advanced melanoma.

Nature Communications
Birkeland, E E; Zhang, S S; Poduval, D D; Geisler, J J; Nakken, S S; Vodak, D D; Meza-Zepeda, L A LA; Hovig, E E; Myklebost, O O; Knappskog, S S; Lønning, P E PE
Publication Date: 2018-07-10

Variant appearance in text: TP53: M133T
PubMed Link: 29991680
Variant Present in the following documents:
  • 41467_2018_5063_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells.

Cell Chemical Biology
Shimada, Kenichi K; Reznik, Eduard E; Stokes, Michael E ME; Krishnamoorthy, Lakshmi L; Bos, Pieter H PH; Song, Yuyu Y; Quartararo, Christine E CE; Pagano, Nen C NC; Carpizo, Darren R DR; deCarvalho, Ana C AC; Lo, Donald C DC; Stockwell, Brent R BR
Publication Date: 2018-05-17

Variant appearance in text: TP53: M133T
PubMed Link: 29576531
Variant Present in the following documents:
  • Main text
View BVdb publication page



Pan-urologic cancer genomic subtypes that transcend tissue of origin.

Nature Communications
Chen, Fengju F; Zhang, Yiqun Y; Bossé, Dominick D; Lalani, Aly-Khan A AA; Hakimi, A Ari AA; Hsieh, James J JJ; Choueiri, Toni K TK; Gibbons, Don L DL; Ittmann, Michael M; Creighton, Chad J CJ
Publication Date: 2017-08-04

Variant appearance in text: TP53: 398T>C; M133T
PubMed Link: 28775315
Variant Present in the following documents:
  • 41467_2017_289_MOESM7_ESM.xlsx, sheet 1
View BVdb publication page



Ligand dependent restoration of human TLR3 signaling and death in p53 mutant cells.

Oncotarget
Menendez, Daniel D; Lowe, Julie M JM; Snipe, Joyce J; Resnick, Michael A MA
Publication Date: 2016-09-20

Variant appearance in text: p53: M133T
PubMed Link: 27533082
Variant Present in the following documents:
  • Main text
  • oncotarget-07-61630-s001.pdf
  • oncotarget-07-61630-s002.xlsx, sheet 1
  • oncotarget-07-61630.pdf
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Reproducible Analysis of Post-Translational Modifications in Proteomes--Application to Human Mutations.

Plos One
Holehouse, Alex S AS; Naegle, Kristen M KM
Publication Date: 2015

Variant appearance in text: rs28934873
PubMed Link: 26659599
Variant Present in the following documents:
  • pone.0144692.s002.xlsx, sheet 1
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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics
Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J
Publication Date: 2015-07-25

Variant appearance in text: TP53: M133T
PubMed Link: 26206375
Variant Present in the following documents:
  • 12859_2015_673_MOESM1_ESM.xls, sheet 1
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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: TP53: M133T
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
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Computational screening and molecular dynamic simulation of breast cancer associated deleterious non-synonymous single nucleotide polymorphisms in TP53 gene.

Plos One
Chitrala, Kumaraswamy Naidu KN; Yeguvapalli, Suneetha S
Publication Date: 2014

Variant appearance in text: TP53: M133T; rs28934873
PubMed Link: 25105660
Variant Present in the following documents:
  • Main text
  • pone.0104242.pdf
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Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss.

Nature Genetics
Gross, Andrew M AM; Orosco, Ryan K RK; Shen, John P JP; Egloff, Ann Marie AM; Carter, Hannah H; Hofree, Matan M; Choueiri, Michel M; Coffey, Charles S CS; Lippman, Scott M SM; Hayes, D Neil DN; Cohen, Ezra E EE; Grandis, Jennifer R JR; Nguyen, Quyen T QT; Ideker, Trey T
Publication Date: 2014-09

Variant appearance in text: rs28934873
PubMed Link: 25086664
Variant Present in the following documents:
  • NIHMS612904-supplement-2.xlsx, sheet 8
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Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups.

Nature Communications
,
Publication Date: 2013

Variant appearance in text: TP53: 398T>C; rs28934873
PubMed Link: 24292195
Variant Present in the following documents:
  • ncomms3873-s2.xls, sheet 1
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Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells.

Oncogene
Zaganjor, E E; Osborne, J K JK; Weil, L M LM; Diaz-Martinez, L A LA; Gonzales, J X JX; Singel, S M SM; Larsen, J E JE; Girard, L L; Minna, J D JD; Cobb, M H MH
Publication Date: 2014-11-20

Variant appearance in text: p53: M133T
PubMed Link: 24240690
Variant Present in the following documents:
  • Main text
  • nihms550264.pdf
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Heritable one-hit events defining cancer prevention?

Cell Cycle (Georgetown, Tex.)
Kopelovich, Levy L; Shea-Herbert, Brittney B
Publication Date: 2013-08-15

Variant appearance in text: p53: M133T
PubMed Link: 23907126
Variant Present in the following documents:
  • Main text
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Assessment of computational methods for predicting the effects of missense mutations in human cancers.

Bmc Genomics
Gnad, Florian F; Baucom, Albion A; Mukhyala, Kiran K; Manning, Gerard G; Zhang, Zemin Z
Publication Date: 2013

Variant appearance in text: TP53: M133T
PubMed Link: 23819521
Variant Present in the following documents:
  • 1471-2164-14-S3-S7-S1.xlsx, sheet 1
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A targeted RNAi screen of the breast cancer genome identifies KIF14 and TLN1 as genes that modulate docetaxel chemosensitivity in triple-negative breast cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Singel, Stina Mui SM; Cornelius, Crystal C; Batten, Kimberly K; Fasciani, Gail G; Wright, Woodring E WE; Lum, Lawrence L; Shay, Jerry W JW
Publication Date: 2013-04-15

Variant appearance in text: p53: M133T
PubMed Link: 23479679
Variant Present in the following documents:
  • Main text
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The human TLR innate immune gene family is differentially influenced by DNA stress and p53 status in cancer cells.

Cancer Research
Shatz, Maria M; Menendez, Daniel D; Resnick, Michael A MA
Publication Date: 2012-08-15

Variant appearance in text: p53: M133T
PubMed Link: 22673234
Variant Present in the following documents:
  • Main text
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Comparable frequency of BRCA1, BRCA2 and TP53 germline mutations in a multi-ethnic Asian cohort suggests TP53 screening should be offered together with BRCA1/2 screening to early-onset breast cancer patients.

Breast Cancer Research : Bcr
Lee, Daphne S C DS; Yoon, Sook-Yee SY; Looi, Lai Meng LM; Kang, Peter P; Kang, In Nee IN; Sivanandan, Kavitta K; Ariffin, Hany H; Thong, Meow Keong MK; Chin, Kin Fah KF; Mohd Taib, Nur Aishah NA; Yip, Cheng-Har CH; Teo, Soo-Hwang SH
Publication Date: 2012-04-16

Variant appearance in text: TP53: M133T
PubMed Link: 22507745
Variant Present in the following documents:
  • Main text
  • bcr3172.pdf
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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research
Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C
Publication Date: 2011-09-01

Variant appearance in text: TP53: M133T
PubMed Link: 21727090
Variant Present in the following documents:
  • supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1
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A new therapeutic basis for treating Li-Fraumeni Syndrome breast tumors expressing mutated TP53.

Oncotarget
Glazer, Robert I RI
Publication Date: 2010-11

Variant appearance in text: TP53: M133T
PubMed Link: 21317445
Variant Present in the following documents:
  • Main text
  • oncotarget-01-470.pdf
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A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers.

Oncotarget
Herbert, Brittney-Shea BS; Chanoux, Rebecca A RA; Liu, Yunlong Y; Baenziger, Peter H PH; Goswami, Chirayu P CP; McClintick, Jeanette N JN; Edenberg, Howard J HJ; Pennington, Robert E RE; Lipkin, Steven M SM; Kopelovich, Levy L
Publication Date: 2010-10

Variant appearance in text: TP53: M133T
PubMed Link: 21311097
Variant Present in the following documents:
  • Main text
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Immortalization of epithelial progenitor cells mediated by resveratrol.

Oncogene
Pearce, V P VP; Sherrell, J J; Lou, Z Z; Kopelovich, L L; Wright, W E WE; Shay, J W JW
Publication Date: 2008-04-10

Variant appearance in text: p53: Met133Thr
PubMed Link: 17968319
Variant Present in the following documents:
  • Main text
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A cancer-associated PCNA expressed in breast cancer has implications as a potential biomarker.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Malkas, Linda H LH; Herbert, Brittney Shea BS; Abdel-Aziz, Waleed W; Dobrolecki, Lacey E LE; Liu, Yang Y; Agarwal, Beamon B; Hoelz, Derek D; Badve, Sunil S; Schnaper, Lauren L; Arnold, Randy J RJ; Mechref, Yehia Y; Novotny, Milos V MV; Loehrer, Patrick P; Goulet, Robert J RJ; Hickey, Robert J RJ
Publication Date: 2006-12-19

Variant appearance in text: p53: M133T
PubMed Link: 17159154
Variant Present in the following documents:
  • Main text
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