Publications:

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: TP53: K120A

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: TP53: K120A

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53.

Bmc Biology

Wong, Jin Huei JH; Alfatah, Mohammad M; Sin, Mei Fang MF; Sim, Hong May HM; Verma, Chandra S CS; Lane, David P DP; Arumugam, Prakash P

Publication Date: 2017-11-09

Variant appearance in text: p53: K120A

PubMed Link: 29121928

Variant Present in the following documents:

• Main text

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EBNA3C regulates p53 through induction of Aurora kinase B.

Oncotarget

Jha, Hem C HC; Yang, Karren K; El-Naccache, Darine W DW; Sun, Zhiguo Z; Robertson, Erle S ES

Publication Date: 2015-03-20

Variant appearance in text: p53: K120A

PubMed Link: 25691063

Variant Present in the following documents:

• Main text
• oncotarget-06-5788.pdf

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: K120A

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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Delivery of a monomeric p53 subdomain with mitochondrial targeting signals from pro-apoptotic Bak or Bax.

Pharmaceutical Research

Matissek, Karina J KJ; Okal, Abood A; Mossalam, Mohanad M; Lim, Carol S CS

Publication Date: 2014-09

Variant appearance in text: p53: K120A

PubMed Link: 24633417

Variant Present in the following documents:

• Main text

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Mapping the structural and dynamical features of multiple p53 DNA binding domains: insights into loop 1 intrinsic dynamics.

Plos One

Lukman, Suryani S; Lane, David P DP; Verma, Chandra S CS

Publication Date: 2013

Variant appearance in text: p53: K120A

PubMed Link: 24324553

Variant Present in the following documents:

• Main text
• pone.0080221.pdf

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Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Arbely, Eyal E; Natan, Eviatar E; Brandt, Tobias T; Allen, Mark D MD; Veprintsev, Dmitry B DB; Robinson, Carol V CV; Chin, Jason W JW; Joerger, Andreas C AC; Fersht, Alan R AR

Publication Date: 2011-05-17

Variant appearance in text: p53: K120A

PubMed Link: 21525412

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• Main text

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The tumor suppressor p53: from structures to drug discovery.

Cold Spring Harbor Perspectives In Biology

Joerger, Andreas C AC; Fersht, Alan R AR

Publication Date: 2010-06

Variant appearance in text: p53: K120A

PubMed Link: 20516128

Variant Present in the following documents:

• Main text

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Two mammalian MOF complexes regulate transcription activation by distinct mechanisms.

Molecular Cell

Li, Xiangzhi X; Wu, Lipeng L; Corsa, Callie Ann Sprunger CA; Kunkel, Steve S; Dou, Yali Y

Publication Date: 2009-10-23

Variant appearance in text: p53: K120A

PubMed Link: 19854137

Variant Present in the following documents:

• Main text

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Crystal structure of a p53 core tetramer bound to DNA.

Oncogene

Malecka, K A KA; Ho, W C WC; Marmorstein, R R

Publication Date: 2009-01-22

Variant appearance in text: p53: K120A

PubMed Link: 18978813

Variant Present in the following documents:

• Main text
• nihms71263.pdf

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Functional role of NF-IL6beta and its sumoylation and acetylation modifications in promoter activation of cyclooxygenase 2 gene.

Nucleic Acids Research

Wang, Ju-Ming JM; Ko, Chiung-Yuan CY; Chen, Lei-Chin LC; Wang, Wen-Lin WL; Chang, Wen-Chang WC

Publication Date: 2006

Variant appearance in text: p53: K120A

PubMed Link: 16397300

Variant Present in the following documents:

• Main text
• gkj422.pdf

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Proteolytic cleavage of p53 mutants in response to mismatched DNA.

British Journal Of Cancer

Mee, T T; Okorokov, A L AL; Metcalfe, S S; Milner, J J

Publication Date: 1999-09

Variant appearance in text: p53: K120A

PubMed Link: 10496344

Variant Present in the following documents:

• 81-6690679a.pdf

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