TP53 c.337_338delinsGC ;(p.F113A)

Variant ID: 17-7579349-AA-GC

NM_000546.5(TP53):c.337_338delinsGC;(p.F113A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Mitotic CDK1 and 4E-BP1 I: Loss of 4E-BP1 serine 82 phosphorylation promotes proliferative polycystic disease and lymphoma in aged or sublethally irradiated mice.

Plos One
Sun, Rui R; Guo, Siying S; Shuda, Yoko Y; Chakka, Anish B AB; Rigatti, Lora H LH; Zhao, Guangyi G; Ali, Mohammed A E MAE; Park, Christopher Y CY; Chandran, Uma U; Yu, Jian J; Bakkenist, Christopher J CJ; Shuda, Masahiro M; Moore, Patrick S PS; Chang, Yuan Y
Publication Date: 2023

Variant appearance in text: p53: F113A
PubMed Link: 37145994
Variant Present in the following documents:
  • Main text
View BVdb publication page



Improving Molecular Therapy in the Kidney.

Molecular Diagnosis & Therapy
Rubin, Jeffrey D JD; Barry, Michael A MA
Publication Date: 2020-08

Variant appearance in text: p53: F113A
PubMed Link: 32323260
Variant Present in the following documents:
  • Main text
View BVdb publication page



A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of protein-protein interactions identifies a novel putative Mdm2-binding site in p53.

Bmc Biology
Wong, Jin Huei JH; Alfatah, Mohammad M; Sin, Mei Fang MF; Sim, Hong May HM; Verma, Chandra S CS; Lane, David P DP; Arumugam, Prakash P
Publication Date: 2017-11-09

Variant appearance in text: p53: F113A
PubMed Link: 29121928
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multisite aggregation of p53 and implications for drug rescue.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Wang, GuoZhen G; Fersht, Alan R AR
Publication Date: 2017-03-28

Variant appearance in text: p53: F113A
PubMed Link: 28292898
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Novel In Vitro CypD-Mediated p53 Aggregation Assay Suggests a Model for Mitochondrial Permeability Transition by Chaperone Systems.

Journal Of Molecular Biology
Lebedev, Ivan I; Nemajerova, Alice A; Foda, Zachariah H ZH; Kornaj, Maja M; Tong, Michael M; Moll, Ute M UM; Seeliger, Markus A MA
Publication Date: 2016-10-09

Variant appearance in text: p53: F113A
PubMed Link: 27515399
Variant Present in the following documents:
  • Main text
View BVdb publication page



Novel mutations target distinct subgroups of medulloblastoma.

Nature
Robinson, Giles G; Parker, Matthew M; Kranenburg, Tanya A TA; Lu, Charles C; Chen, Xiang X; Ding, Li L; Phoenix, Timothy N TN; Hedlund, Erin E; Wei, Lei L; Zhu, Xiaoyan X; Chalhoub, Nader N; Baker, Suzanne J SJ; Huether, Robert R; Kriwacki, Richard R; Curley, Natasha N; Thiruvenkatam, Radhika R; Wang, Jianmin J; Wu, Gang G; Rusch, Michael M; Hong, Xin X; Becksfort, Jared J; Gupta, Pankaj P; Ma, Jing J; Easton, John J; Vadodaria, Bhavin B; Onar-Thomas, Arzu A; Lin, Tong T; Li, Shaoyi S; Pounds, Stanley S; Paugh, Steven S; Zhao, David D; Kawauchi, Daisuke D; Roussel, Martine F MF; Finkelstein, David D; Ellison, David W DW; Lau, Ching C CC; Bouffet, Eric E; Hassall, Tim T; Gururangan, Sridharan S; Cohn, Richard R; Fulton, Robert S RS; Fulton, Lucinda L LL; Dooling, David J DJ; Ochoa, Kerri K; Gajjar, Amar A; Mardis, Elaine R ER; Wilson, Richard K RK; Downing, James R JR; Zhang, Jinghui J; Gilbertson, Richard J RJ
Publication Date: 2012-08-02

Variant appearance in text: TP53: F113A
PubMed Link: 22722829
Variant Present in the following documents:
  • NIHMS374717-supplement-info.pdf
View BVdb publication page