TP53 c.280T>G ;(p.S94A)

Variant ID: 17-7579407-A-C

NM_000546.5(TP53):c.280T>G;(p.S94A)

This variant was identified in 12 publications

View GRCh38 version.




Publications:


Weight-bearing activity impairs nuclear membrane and genome integrity via YAP activation in plantar melanoma.

Nature Communications
Seo, Jimyung J; Kim, HyunSeok H; Min, Kyoung Il KI; Kim, Changgon C; Kwon, Yongsoo Y; Zheng, Zhenlong Z; Kim, Yusung Y; Park, Hyung-Soon HS; Ju, Young Seok YS; Roh, Mi Ryung MR; Chung, Kee Yang KY; Kim, Joon J
Publication Date: 2022-04-25

Variant appearance in text: TP53: S94A
PubMed Link: 35468978
Variant Present in the following documents:
  • Main text
  • 41467_2022_Article_29925.pdf
View BVdb publication page



Prevalence and variation of CHIP in patients with aggressive lymphomas undergoing CD19-directed CAR T-cell treatment.

Blood Advances
Teipel, Raphael R; Kroschinsky, Frank F; Kramer, Michael M; Kretschmann, Theresa T; Egger-Heidrich, Katharina K; Krüger, Thomas T; Ruhnke, Leo L; Herold, Sylvia S; Stasik, Sebastian S; Sockel, Katja K; Middeke, Jan M JM; Trautmann-Grill, Karolin K; Bornhäuser, Martin M; Thiede, Christian C; von Bonin, Malte M
Publication Date: 2022-03-22

Variant appearance in text: TP53: 280T>G; Ser94Ala
PubMed Link: 35008107
Variant Present in the following documents:
  • advancesADV2021005747-suppl1.pdf
View BVdb publication page



A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports
Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM
Publication Date: 2021-07-12

Variant appearance in text: TP53: S94A
PubMed Link: 34253785
Variant Present in the following documents:
  • 41598_2021_93715_MOESM3_ESM.xlsx, sheet 6
View BVdb publication page



appreci8: a pipeline for precise variant calling integrating 8 tools.

Bioinformatics (Oxford, England)
Sandmann, Sarah S; Karimi, Mohsen M; de Graaf, Aniek O AO; Rohde, Christian C; Göllner, Stefanie S; Varghese, Julian J; Ernsting, Jan J; Walldin, Gunilla G; van der Reijden, Bert A BA; Müller-Tidow, Carsten C; Malcovati, Luca L; Hellström-Lindberg, Eva E; Jansen, Joop H JH; Dugas, Martin M
Publication Date: 2018-12-15

Variant appearance in text: TP53: 280T>G; Ser94Ala
PubMed Link: 29945233
Variant Present in the following documents:
  • bty518_supplementary_data_s2.xlsx, sheet 8
  • bty518_supplementary_data_s2.xlsx, sheet 9
  • bty518_supplementary_data_s6.xlsx, sheet 9
  • bty518_supplementary_data_s3.xlsx, sheet 9
View BVdb publication page



Expression of cell cycle regulators and frequency of TP53 mutations in high risk gastrointestinal stromal tumors prior to adjuvant imatinib treatment.

Plos One
Ihle, Michaela Angelika MA; Huss, Sebastian S; Jeske, Wiebke W; Hartmann, Wolfgang W; Merkelbach-Bruse, Sabine S; Schildhaus, Hans-Ulrich HU; Büttner, Reinhard R; Sihto, Harri H; Sundby Hall, Kirsten K; Eriksson, Mikael M; Reichardt, Peter P; Joensuu, Heikki H; Wardelmann, Eva E
Publication Date: 2018

Variant appearance in text: p53: S94A
PubMed Link: 29451912
Variant Present in the following documents:
  • Main text
  • pone.0193048.pdf
View BVdb publication page



High mobility group protein B1 controls liver cancer initiation through yes-associated protein -dependent aerobic glycolysis.

Hepatology (Baltimore, Md.)
Chen, Ruochan R; Zhu, Shan S; Fan, Xue-Gong XG; Wang, Haichao H; Lotze, Michael T MT; Zeh, Herbert J HJ; Billiar, Timothy R TR; Kang, Rui R; Tang, Daolin D
Publication Date: 2018-05

Variant appearance in text: p53: S94A
PubMed Link: 29149457
Variant Present in the following documents:
  • Main text
View BVdb publication page



Preparation of 6/8/11-Amino/Chloro-Oxoisoaporphine and Group-10 Metal Complexes and Evaluation of Their in Vitro and in Vivo Antitumor Activity.

Scientific Reports
Qin, Qi-Pin QP; Qin, Jiao-Lan JL; Meng, Ting T; Yang, Gui-Ai GA; Wei, Zu-Zhuang ZZ; Liu, Yan-Cheng YC; Liang, Hong H; Chen, Zhen-Feng ZF
Publication Date: 2016-11-29

Variant appearance in text: TP53: S94A
PubMed Link: 27898051
Variant Present in the following documents:
  • Main text
  • srep37644.pdf
View BVdb publication page



iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: S94A
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
View BVdb publication page



Yes-associated protein (YAP) increases chemosensitivity of hepatocellular carcinoma cells by modulation of p53.

Cancer Biology & Therapy
Bai, Nan N; Zhang, Chunyan C; Liang, Ning N; Zhang, Zhuhong Z; Chang, Antao A; Yin, Jing J; Li, Zongjin Z; Luo, Na N; Tan, Xiaoyue X; Luo, Na N; Luo, Yunping Y; Xiang, Rong R; Li, Xiru X; Reisfeld, Ralph A RA; Stupack, Dwayne D; Lv, Dan D; Liu, Chenghu C
Publication Date: 2013-06

Variant appearance in text: p53: S94A
PubMed Link: 23760493
Variant Present in the following documents:
  • Main text
View BVdb publication page



Dimerization and direct membrane interaction of Nup53 contribute to nuclear pore complex assembly.

The Embo Journal
Vollmer, Benjamin B; Schooley, Allana A; Sachdev, Ruchika R; Eisenhardt, Nathalie N; Schneider, Anna M AM; Sieverding, Cornelia C; Madlung, Johannes J; Gerken, Uwe U; Macek, Boris B; Antonin, Wolfram W
Publication Date: 2012-10-17

Variant appearance in text: p53: S94A
PubMed Link: 22960634
Variant Present in the following documents:
  • emboj2012256s1.pdf
View BVdb publication page



α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1.

Science Signaling
Silvis, Mark R MR; Kreger, Bridget T BT; Lien, Wen-Hui WH; Klezovitch, Olga O; Rudakova, G Marianna GM; Camargo, Fernando D FD; Lantz, Dan M DM; Seykora, John T JT; Vasioukhin, Valeri V
Publication Date: 2011-05-24

Variant appearance in text: p53: S94A
PubMed Link: 21610251
Variant Present in the following documents:
  • Main text
View BVdb publication page



Androgen receptor signalling in prostate cancer: the functional consequences of acetylation.

Journal Of Biomedicine & Biotechnology
Lavery, Derek N DN; Bevan, Charlotte L CL
Publication Date: 2011

Variant appearance in text: p53: S94A
PubMed Link: 21274273
Variant Present in the following documents:
  • Main text
  • JBB2011-862125.pdf
View BVdb publication page