Publications:

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Whole-exome Sequencing of Nigerian Prostate Tumors from the Prostate Cancer Transatlantic Consortium (CaPTC) Reveals DNA Repair Genes Associated with African Ancestry.

Cancer Research Communications

White, Jason A JA; Kaninjing, Ernest T ET; Adeniji, Kayode A KA; Jibrin, Paul P; Obafunwa, John O JO; Ogo, Chidiebere N CN; Mohammed, Faruk F; Popoola, Ademola A; Fatiregun, Omolara A OA; Oluwole, Olabode P OP; Karanam, Balasubramanyam B; Elhussin, Isra I; Ambs, Stefan S; Tang, Wei W; Davis, Melissa M; Polak, Paz P; Campbell, Moray J MJ; Brignole, Kathryn R KR; Rotimi, Solomon O SO; Dean-Colomb, Windy W; Odedina, Folake T FT; Martin, Damali N DN; Yates, Clayton C

Publication Date: 2022-09

Variant appearance in text: TP53: P85S

PubMed Link: 36922933

Variant Present in the following documents:

• crc-22-0136-s01.xlsx, sheet 1

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: TP53: Pro85Ser

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: p53: 253C>T

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

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In-depth characterization of intratumoral heterogeneity in refractory B-cell non-Hodgkin lymphoma through the lens of a Research Autopsy Program.

Haematologica

Isaev, Keren K; Liu, Ting T; Bakhtiari, Mehran M; Tong, Kit K; Goswami, Rashmi R; Lam, Bernard B; Lungu, Ilinca I; Krzyzanowski, Paul M PM; Oza, Amit A; Dhani, Neesha N; Prica, Anca A; Crump, Michael M; Kridel, Robert R

Publication Date: 2022-06-23

Variant appearance in text: TP53: P85S

PubMed Link: 35734926

Variant Present in the following documents:

• Main text
• 108196.pdf

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Targeting PI3K/Akt signal transduction for cancer therapy.

Signal Transduction And Targeted Therapy

He, Yan Y; Sun, Miao Miao MM; Zhang, Guo Geng GG; Yang, Jing J; Chen, Kui Sheng KS; Xu, Wen Wen WW; Li, Bin B

Publication Date: 2021-12-16

Variant appearance in text: p53: p85s

PubMed Link: 34916492

Variant Present in the following documents:

• 41392_2021_Article_828.pdf

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The regulatory subunits of PI3K, p85α and p85β, differentially affect BRD7-mediated regulation of insulin signaling.

Journal Of Molecular Cell Biology

Lee, Junsik M JM; Liu, Renyan R; Park, Sang Won SW

Publication Date: 2021-11-09

Variant appearance in text: p53: p85s

PubMed Link: 34751372

Variant Present in the following documents:

• mjab073.pdf

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The regulatory subunits of PI3K, p85α and p85β, differentially affect BRD7-mediated regulation of insulin signaling.

Journal Of Molecular Cell Biology

Lee, Junsik M JM; Liu, Renyan R; Park, Sang Won SW

Publication Date: 2022-01-29

Variant appearance in text: p53: p85s

PubMed Link: 34751372

Variant Present in the following documents:

• mjab073.pdf

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Multi-omics profiling of primary small cell carcinoma of the esophagus reveals RB1 disruption and additional molecular subtypes.

Nature Communications

Li, Renda R; Yang, Zhenlin Z; Shao, Fei F; Cheng, Hong H; Wen, Yaru Y; Sun, Sijin S; Guo, Wei W; Li, Zitong Z; Zhang, Fan F; Xue, Liyan L; Bi, Nan N; Wang, Jie J; Sun, Yingli Y; Li, Yin Y; Tan, Fengwei F; Xue, Qi Q; Gao, Shugeng S; Shi, Susheng S; Gao, Yibo Y; He, Jie J

Publication Date: 2021-06-18

Variant appearance in text: TP53: 253C>T

PubMed Link: 34145257

Variant Present in the following documents:

• 41467_2021_24043_MOESM5_ESM.xlsx, sheet 1

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Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: TP53: 253C>T; P85S

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: TP53: 253C>T; P85S

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Emerging Roles of BRD7 in Pathophysiology.

International Journal Of Molecular Sciences

Park, Sang Won SW; Lee, Junsik M JM

Publication Date: 2020-09-27

Variant appearance in text: p53: p85s

PubMed Link: 32992509

Variant Present in the following documents:

• Main text
• ijms-21-07127.pdf

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Class IA PI3K regulatory subunits: p110-independent roles and structures.

Biochemical Society Transactions

Fox, Millie M; Mott, Helen R HR; Owen, Darerca D

Publication Date: 2020-08-28

Variant appearance in text: p53: p85s

PubMed Link: 32677674

Variant Present in the following documents:

• Main text
• BST-48-1397.pdf

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: TP53: P85S

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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Decoding Somatic Driver Gene Mutations and Affected Signaling Pathways in Human Medulloblastoma Subgroups.

Journal Of Cancer

Robbins, Charles J CJ; Bou-Dargham, Mayassa J MJ; Sanchez, Kevin K; Rosen, Matthew C MC; Sang, Qing-Xiang Amy QA

Publication Date: 2018

Variant appearance in text: TP53: 253C>T

PubMed Link: 30588243

Variant Present in the following documents:

• jcav09p4596s2.xlsx, sheet 1

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Design and MinION testing of a nanopore targeted gene sequencing panel for chronic lymphocytic leukemia.

Scientific Reports

Orsini, Paola P; Minervini, Crescenzio F CF; Cumbo, Cosimo C; Anelli, Luisa L; Zagaria, Antonella A; Minervini, Angela A; Coccaro, Nicoletta N; Tota, Giuseppina G; Casieri, Paola P; Impera, Luciana L; Parciante, Elisa E; Brunetti, Claudia C; Giordano, Annamaria A; Specchia, Giorgina G; Albano, Francesco F

Publication Date: 2018-08-07

Variant appearance in text: TP53: P85S

PubMed Link: 30087429

Variant Present in the following documents:

• 41598_2018_30330_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Mutation allele frequency threshold does not affect prognostic analysis using next-generation sequencing in oral squamous cell carcinoma.

Bmc Cancer

Ma, Jie J; Fu, Yong Y; Tu, Yao-Yao YY; Liu, Ying Y; Tan, Yi-Ran YR; Ju, Wu-Tong WT; Pickering, Curtis R CR; Myers, Jeffrey N JN; Zhang, Zhi-Yuan ZY; Zhong, Lai-Ping LP

Publication Date: 2018-07-24

Variant appearance in text: p53: Pro85Ser

PubMed Link: 30041611

Variant Present in the following documents:

• Main text
• 12885_2018_Article_4481.pdf

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Random Mutagenesis, Clonal Events, and Embryonic or Somatic Origin Determine the mtDNA Variant Type and Load in Human Pluripotent Stem Cells.

Stem Cell Reports

Zambelli, Filippo F; Mertens, Joke J; Dziedzicka, Dominika D; Sterckx, Johan J; Markouli, Christina C; Keller, Alexander A; Tropel, Philippe P; Jung, Laura L; Viville, Stephane S; Van de Velde, Hilde H; Geens, Mieke M; Seneca, Sara S; Sermon, Karen K; Spits, Claudia C

Publication Date: 2018-07-10

Variant appearance in text: p53: P85S

PubMed Link: 29910126

Variant Present in the following documents:

• mmc1.pdf
• mmc2.pdf

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Germ-line and somatic EPHA2 coding variants in lens aging and cataract.

Plos One

Bennett, Thomas M TM; M'Hamdi, Oussama O; Hejtmancik, J Fielding JF; Shiels, Alan A

Publication Date: 2017

Variant appearance in text: TP53: P85S

PubMed Link: 29267365

Variant Present in the following documents:

• pone.0189881.s007.xlsx, sheet 1

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BRD7 regulates the insulin-signaling pathway by increasing phosphorylation of GSK3β.

Cellular And Molecular Life Sciences : Cmls

Golick, Lena L; Han, Youngah Y; Kim, Yoo Y; Park, Sang Won SW

Publication Date: 2018-05

Variant appearance in text: p53: p85s

PubMed Link: 29127434

Variant Present in the following documents:

• Main text

View BVdb publication page

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Aggregation and Prion-Like Properties of Misfolded Tumor Suppressors: Is Cancer a Prion Disease?

Cold Spring Harbor Perspectives In Biology

Costa, Danielly C F DC; de Oliveira, Guilherme A P GA; Cino, Elio A EA; Soares, Iaci N IN; Rangel, Luciana P LP; Silva, Jerson L JL

Publication Date: 2016-10-03

Variant appearance in text: p53: P85S

PubMed Link: 27549118

Variant Present in the following documents:

• Main text

View BVdb publication page

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: P85S

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

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The role of BRD7 in embryo development and glucose metabolism.

Journal Of Cellular And Molecular Medicine

Kim, Yoo Y; Andrés Salazar Hernández, Mario M; Herrema, Hilde H; Delibasi, Tuncay T; Park, Sang Won SW

Publication Date: 2016-08

Variant appearance in text: p53: p85s

PubMed Link: 27444544

Variant Present in the following documents:

• Main text
• JCMM-20-1561.pdf

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Recurrent inactivating RASA2 mutations in melanoma.

Nature Genetics

Arafeh, Rand R; Qutob, Nouar N; Emmanuel, Rafi R; Keren-Paz, Alona A; Madore, Jason J; Elkahloun, Abdel A; Wilmott, James S JS; Gartner, Jared J JJ; Di Pizio, Antonella A; Winograd-Katz, Sabina S; Sindiri, Sivasish S; Rotkopf, Ron R; Dutton-Regester, Ken K; Johansson, Peter P; Pritchard, Antonia L AL; Waddell, Nicola N; Hill, Victoria K VK; Lin, Jimmy C JC; Hevroni, Yael Y; Rosenberg, Steven A SA; Khan, Javed J; Ben-Dor, Shifra S; Niv, Masha Y MY; Ulitsky, Igor I; Mann, Graham J GJ; Scolyer, Richard A RA; Hayward, Nicholas K NK; Samuels, Yardena Y

Publication Date: 2015-12

Variant appearance in text: p53: P85S

PubMed Link: 26502337

Variant Present in the following documents:

• NIHMS65345-supplement-Supplementary_table_3.xlsx, sheet 2

View BVdb publication page

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: TP53: P85S

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 1

View BVdb publication page

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Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer.

Frontiers In Oncology

de Oliveira, Guilherme A P GA; Rangel, Luciana P LP; Costa, Danielly C DC; Silva, Jerson L JL

Publication Date: 2015

Variant appearance in text: p53: P85S

PubMed Link: 25973395

Variant Present in the following documents:

• Main text
• fonc-05-00097.pdf

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: P85S

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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Astragalus saponins modulates colon cancer development by regulating calpain-mediated glucose-regulated protein expression.

Bmc Complementary And Alternative Medicine

Wang, Yue Y; Auyeung, Kathy K KK; Zhang, Xiaoyu X; Ko, Joshua K JK

Publication Date: 2014-10-15

Variant appearance in text: p53: p85s

PubMed Link: 25319833

Variant Present in the following documents:

• Main text
• 12906_2014_Article_1977.pdf

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BRD7 regulates XBP1s' activity and glucose homeostasis through its interaction with the regulatory subunits of PI3K.

Cell Metabolism

Park, Sang Won SW; Herrema, Hilde H; Salazar, Mario M; Cakir, Isin I; Cabi, Serkan S; Basibuyuk Sahin, Fatma F; Chiu, Yu-Hsin YH; Cantley, Lewis C LC; Ozcan, Umut U

Publication Date: 2014-07-01

Variant appearance in text: p53: p85s

PubMed Link: 24836559

Variant Present in the following documents:

• Main text

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Potential for therapeutic manipulation of the UPR in disease.

Seminars In Immunopathology

Park, Sang Won SW; Ozcan, Umut U

Publication Date: 2013-05

Variant appearance in text: p53: p85s

PubMed Link: 23572207

Variant Present in the following documents:

• Main text
• 281_2013_Article_370.pdf

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High frequency of complex TP53 mutations in CNS metastases from breast cancer.

British Journal Of Cancer

Lo Nigro, C C; Vivenza, D D; Monteverde, M M; Lattanzio, L L; Gojis, O O; Garrone, O O; Comino, A A; Merlano, M M; Quinlan, P R PR; Syed, N N; Purdie, C A CA; Thompson, A A; Palmieri, C C; Crook, T T

Publication Date: 2012-01-17

Variant appearance in text: TP53: Pro85Ser

PubMed Link: 22187033

Variant Present in the following documents:

• Main text
• bjc2011464a.pdf

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: TP53: P85S

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

View BVdb publication page

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