Publications:

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Pan-cancer clinical impact of latent drivers from double mutations.

Communications Biology

Yavuz, Bengi Ruken BR; Tsai, Chung-Jung CJ; Nussinov, Ruth R; Tuncbag, Nurcan N

Publication Date: 2023-02-20

Variant appearance in text: TP53: A78T

PubMed Link: 36808143

Variant Present in the following documents:

• 42003_2023_4519_MOESM3_ESM.xlsx, sheet 2

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: TP53: A78T

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: p53: 232G>A

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1
• mmc5.xlsx, sheet 1

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Identification of Prognosis-Related Molecular Subgroups and Construction of a Prognostic Prediction Model Using Immune-Related Genes in Pancreatic Cancer.

Journal Of Oncology

Fei, Xiang X; Kong, Lingming L; Shi, Chao C; Wang, Gang G; Liu, Chenhai C; Wang, Cheng C; Liu, Peng P; Tan, Xiaodong X

Publication Date: 2022

Variant appearance in text: TP53: A78T

PubMed Link: 35712127

Variant Present in the following documents:

• JO2022-7117014.pdf

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Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis.

Clinical And Translational Gastroenterology

Cowan, Robert W RW; Pratt, Erica D ED; Kang, Jin Muk JM; Zhao, Jun J; Wilhelm, Joshua J JJ; Abdulla, Muhamad M; Qiao, Edmund M EM; Brennan, Luke P LP; Ulintz, Peter J PJ; Bellin, Melena D MD; Rhim, Andrew D AD

Publication Date: 2021-11-18

Variant appearance in text: TP53: 232G>A; Ala78Thr

PubMed Link: 34797250

Variant Present in the following documents:

• ct9-12-e00431-s005.xlsx, sheet 1
• ct9-12-e00431-s006.xlsx, sheet 1

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PD-L1 targeting and subclonal immune escape mediated by PD-L1 mutations in metastatic colorectal cancer.

Journal For Immunotherapy Of Cancer

Stein, Alexander A; Simnica, Donjete D; Schultheiß, Christoph C; Scholz, Rebekka R; Tintelnot, Joseph J; Gökkurt, Eray E; von Wenserski, Lisa L; Willscher, Edith E; Paschold, Lisa L; Sauer, Markus M; Lorenzen, Sylvie S; Riera-Knorrenschild, Jorge J; Depenbusch, Reinhard R; Ettrich, Thomas J TJ; Dörfel, Steffen S; Al-Batran, Salah-Eddin SE; Karthaus, Meinolf M; Pelzer, Uwe U; Waberer, Lisa L; Hinke, Axel A; Bauer, Marcus M; Massa, Chiara C; Seliger, Barbara B; Wickenhauser, Claudia C; Bokemeyer, Carsten C; Hegewisch-Becker, Susanna S; Binder, Mascha M

Publication Date: 2021-07

Variant appearance in text: TP53: 232G>A

PubMed Link: 34315821

Variant Present in the following documents:

• jitc-2021-002844supp002.xlsx, sheet 1

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A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports

Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM

Publication Date: 2021-07-12

Variant appearance in text: TP53: 232G>A; Ala78Thr

PubMed Link: 34253785

Variant Present in the following documents:

• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 8

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Profiling of conditionally reprogrammed cell lines for in vitro chemotherapy response prediction of pancreatic cancer.

Ebiomedicine

Lee, Hee Seung HS; Kim, Eunyoung E; Lee, Jinyoung J; Park, Seung Joon SJ; Hwang, Ho Kyoung HK; Park, Chan Hee CH; Jo, Se-Young SY; Kang, Chang Moo CM; Hong, Seung-Mo SM; Kang, Huapyong H; Jo, Jung Hyun JH; Cho, In Rae IR; Chung, Moon Jae MJ; Park, Jeong Youp JY; Park, Seung Woo SW; Song, Si Young SY; Han, Jung Min JM; Kim, Sangwoo S; Bang, Seungmin S

Publication Date: 2021-03

Variant appearance in text: TP53: A78T

PubMed Link: 33639403

Variant Present in the following documents:

• mmc2.pdf

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High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants.

Nature Medicine

Razavi, Pedram P; Li, Bob T BT; Brown, David N DN; Jung, Byoungsok B; Hubbell, Earl E; Shen, Ronglai R; Abida, Wassim W; Juluru, Krishna K; De Bruijn, Ino I; Hou, Chenlu C; Venn, Oliver O; Lim, Raymond R; Anand, Aseem A; Maddala, Tara T; Gnerre, Sante S; Vijaya Satya, Ravi R; Liu, Qinwen Q; Shen, Ling L; Eattock, Nicholas N; Yue, Jeanne J; Blocker, Alexander W AW; Lee, Mark M; Sehnert, Amy A; Xu, Hui H; Hall, Megan P MP; Santiago-Zayas, Angie A; Novotny, William F WF; Isbell, James M JM; Rusch, Valerie W VW; Plitas, George G; Heerdt, Alexandra S AS; Ladanyi, Marc M; Hyman, David M DM; Jones, David R DR; Morrow, Monica M; Riely, Gregory J GJ; Scher, Howard I HI; Rudin, Charles M CM; Robson, Mark E ME; Diaz, Luis A LA; Solit, David B DB; Aravanis, Alexander M AM; Reis-Filho, Jorge S JS

Publication Date: 2019-12

Variant appearance in text: TP53: Ala78Thr

PubMed Link: 31768066

Variant Present in the following documents:

• NIHMS1541314-supplement-1541314_Sup_Tab.xlsx, sheet 5

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From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.

Cold Spring Harbor Molecular Case Studies

Quinn, Emily A EA; Maciaszek, Jamie L JL; Pinto, Emilia M EM; Phillips, Aaron H AH; Berdy, David D; Khandwala, Mohammad M; Upadhyaya, Santhosh A SA; Zambetti, Gerard P GP; Kriwacki, Richard W RW; Ellison, David W DW; Nichols, Kim E KE; Kesserwan, Chimene C

Publication Date: 2019-08

Variant appearance in text: TP53: 232G>A; Ala78Thr

PubMed Link: 30886117

Variant Present in the following documents:

• supp_mcs.a003921_Supplemental_Table_1a.xlsx, sheet 1

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Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma.

Hepatology (Baltimore, Md.)

Goeppert, Benjamin B; Toth, Reka R; Singer, Stephan S; Albrecht, Thomas T; Lipka, Daniel B DB; Lutsik, Pavlo P; Brocks, David D; Baehr, Marion M; Muecke, Oliver O; Assenov, Yassen Y; Gu, Lei L; Endris, Volker V; Stenzinger, Albrecht A; Mehrabi, Arianeb A; Schirmacher, Peter P; Plass, Christoph C; Weichenhan, Dieter D; Roessler, Stephanie S

Publication Date: 2019-05

Variant appearance in text: TP53: A78T

PubMed Link: 30615206

Variant Present in the following documents:

• HEP-69-2091-s001.pdf

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Comprehensive Validation of Snapback Primer-Based Melting Curve Analysis to Detect Nucleotide Variation in the Codon 12 and 13 of KRAS Gene.

Biomed Research International

Zhang, Qunfeng Q; Du, Yiqiao Y; Zhang, Xinju X; Kang, Zhihua Z; Guan, Ming M; Wu, Zhiyuan Z

Publication Date: 2018

Variant appearance in text: TP53: A78T

PubMed Link: 30406144

Variant Present in the following documents:

• Main text

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Mitochondrial Dysfunctions in Type I Endometrial Carcinoma: Exploring Their Role in Oncogenesis and Tumor Progression.

International Journal Of Molecular Sciences

Musicco, Clara C; Cormio, Gennaro G; Pesce, Vito V; Loizzi, Vera V; Cicinelli, Ettore E; Resta, Leonardo L; Ranieri, Girolamo G; Cormio, Antonella A

Publication Date: 2018-07-17

Variant appearance in text: TP53: A78T

PubMed Link: 30018222

Variant Present in the following documents:

• Main text

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Somatic mutations in salivary duct carcinoma and potential therapeutic targets.

Oncotarget

Khoo, Timothy K TK; Yu, Bing B; Smith, Joel A JA; Clarke, Angus J AJ; Luk, Peter P PP; Selinger, Christina I CI; Mahon, Kate L KL; Kraitsek, Spiridoula S; Palme, Carsten C; Boyer, Michael J MJ; Dinger, Marcel E ME; Cowley, Mark J MJ; O'Toole, Sandra A SA; Clark, Jonathan R JR; Gupta, Ruta R

Publication Date: 2017-09-29

Variant appearance in text: TP53: 232G>A

PubMed Link: 29100278

Variant Present in the following documents:

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Biochemical and genetic predictors of overall survival in patients with metastatic pancreatic cancer treated with capecitabine and nab-paclitaxel.

Scientific Reports

Bianconi, Daniela D; Heller, Gerwin G; Spies, Daniel D; Herac, Merima M; Gleiss, Andreas A; Liebmann-Reindl, Sandra S; Unseld, Matthias M; Kieler, Markus M; Scheithauer, Werner W; Streubel, Berthold B; Zielinski, Christoph C CC; Prager, Gerald W GW

Publication Date: 2017-07-07

Variant appearance in text: TP53: A78T

PubMed Link: 28687745

Variant Present in the following documents:

• 41598_2017_4743_MOESM1_ESM.pdf

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TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions.

Elife

Shirole, Nitin H NH; Pal, Debjani D; Kastenhuber, Edward R ER; Senturk, Serif S; Boroda, Joseph J; Pisterzi, Paola P; Miller, Madison M; Munoz, Gustavo G; Anderluh, Marko M; Ladanyi, Marc M; Lowe, Scott W SW; Sordella, Raffaella R

Publication Date: 2016-10-19

Variant appearance in text: p53: A78T

PubMed Link: 27759562

Variant Present in the following documents:

• elife-17929-supp2.xlsx, sheet 1

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: A78T

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

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REGene: a literature-based knowledgebase of animal regeneration that bridge tissue regeneration and cancer.

Scientific Reports

Zhao, Min M; Rotgans, Bronwyn B; Wang, Tianfang T; Cummins, S F SF

Publication Date: 2016-03-15

Variant appearance in text: TP53: A78T

PubMed Link: 26975833

Variant Present in the following documents:

• srep23167-s9.xls, sheet 1

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High frequency of complex TP53 mutations in CNS metastases from breast cancer.

British Journal Of Cancer

Lo Nigro, C C; Vivenza, D D; Monteverde, M M; Lattanzio, L L; Gojis, O O; Garrone, O O; Comino, A A; Merlano, M M; Quinlan, P R PR; Syed, N N; Purdie, C A CA; Thompson, A A; Palmieri, C C; Crook, T T

Publication Date: 2012-01-17

Variant appearance in text: TP53: Ala78Thr

PubMed Link: 22187033

Variant Present in the following documents:

• Main text
• bjc2011464a.pdf

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