Publications:

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Molecular Bases of Mechanisms Accounting for Drug Resistance in Gastric Adenocarcinoma.

Cancers

JJG Marin, L Perez-Silva, RIR Macias, M Asensio, A Peleteiro-Vigil, A Sanchez-Martin, C Cives-Losada, P Sanchon-Sanchez, B Sanchez De Blas, E Herraez, O Briz, E Lozano

Publication Date: 2020-07-30

Variant appearance in text: N/A

PMID: 32751679

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Both p53 codon 72 Arg/Arg and pro/Arg genotypes in glioblastoma multiforme are associated with a better prognosis in bevacizumab treatment.

Bmc Cancer

CC Shen, WY Cheng, CH Lee, XJ Dai, MT Chiao, YJ Liang, WY Hsieh, TF Mao, GS Lin, SR Chen, BS Liu, JP Chen

Publication Date: 2020-07-29

Variant appearance in text: N/A

PMID: 32727419

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High-Throughput Sequencing of Gastric Cancer Patients: Unravelling Genetic Predispositions Towards an Early-Onset Subtype.

Cancers

J Machlowska, P Kapusta, J Baj, FHM Morsink, P Wołkow, R Maciejewski, GJA Offerhaus, R Sitarz

Publication Date: 2020-07-21

Variant appearance in text: N/A

PMID: 32708070

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Plasma circulating tumor DNA assessment reveals KMT2D as a potential poor prognostic factor in extranodal NK/T-cell lymphoma.

Biomarker Research

Q Li, W Zhang, J Li, J Xiong, J Liu, T Chen, Q Wen, Y Zeng, L Gao, L Gao, C Zhang, P Kong, X Peng, Y Liu, X Zhang, J Rao

Publication Date: 2020

Variant appearance in text: TP53: P72R

PMID: 32695399

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Somatic Mutation Profiling in Premalignant Lesions of Vulvar Squamous Cell Carcinoma.

International Journal Of Molecular Sciences

S Zięba, AW Pouwer, A Kowalik, K Zalewski, N Rusetska, E Bakuła-Zalewska, J Kopczyński, JMA Pijnenborg, JA de Hullu, M Kowalewska

Publication Date: 2020-07-10

Variant appearance in text: TP53: P72R

PMID: 32664330

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Novel Genetic Variations in Acute Myeloid Leukemia in Pakistani Population.

Frontiers In Genetics

S Shahid, M Shakeel, S Siddiqui, S Ahmed, M Sohail, IA Khan, A Abid, T Shamsi

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32655615

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Beyond the HLA polymorphism: A complex pattern of genetic susceptibility to pemphigus.

Genetics And Molecular Biology

ML Petzl-Erler

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32639508

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XAF1 as a modifier of p53 function and cancer susceptibility.

Science Advances

EM Pinto, BC Figueiredo, W Chen, HCR Galvao, MN Formiga, MCBV Fragoso, P Ashton-Prolla, EMSF Ribeiro, G Felix, TEB Costa, SA Savage, M Yeager, EI Palmero, S Volc, H Salvador, JL Fuster-Soler, C Lavarino, G Chantada, D Vaur, V Odone-Filho, L Brugières, T Else, EM Stoffel, KN Maxwell, MI Achatz, L Kowalski, KC de Andrade, A Pappo, E Letouze, AC Latronico, BB Mendonca, MQ Almeida, VB Brondani, CM Bittar, EWS Soares, C Mathias, CRN Ramos, M Machado, W Zhou, K Jones, A Vogt, PP Klincha, KM Santiago, H Komechen, MM Paraizo, IZS Parise, KV Hamilton, J Wang, E Rampersaud, MR Clay, AJ Murphy, E Lalli, KE Nichols, RC Ribeiro, C Rodriguez-Galindo, M Korbonits, J Zhang, MG Thomas, JP Connelly, S Pruett-Miller, Y Diekmann, G Neale, G Wu, GP Zambetti

Publication Date: 2020-06

Variant appearance in text: N/A

PMID: 32637605

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Pharmacogenomics and Pharmacogenetics in Osteosarcoma: Translational Studies and Clinical Impact.

International Journal Of Molecular Sciences

CM Hattinger, MP Patrizio, S Luppi, M Serra

Publication Date: 2020-06-30

Variant appearance in text: N/A

PMID: 32629971

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Mutation profiling of anaplastic ependymoma grade III by Ion Proton next generation DNA sequencing.

F1000Research

E Butt, S Alyami, T Nageeti, M Saeed, K AlQuthami, A Bouazzaoui, M Athar, Z Abduljaleel, F Al-Allaf, M Taher

Publication Date: 2019

Variant appearance in text: TP53: 215C>G; Pro72Arg; rs1042522

PMID: 32612806

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Single Nucleotide Variants Associated with Colorectal Cancer Among Iranian Patients: A Narrative Review.

Pharmacogenomics And Personalized Medicine

M Jamshidi, S Mohammadi Pour, MR Mahmoudian-Sani

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32581566

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Ex vivo modelling of drug efficacy in a rare metastatic urachal carcinoma.

Bmc Cancer

R Mäkelä, A Arjonen, V Härmä, N Rintanen, L Paasonen, T Paprotka, K Rönsch, T Kuopio, J Kononen, JK Rantala

Publication Date: 2020-06-23

Variant appearance in text: TP53: P72R

PMID: 32576176

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A novel hotspot and rare somatic mutation p.A138V, at TP53 is associated with poor survival of pancreatic ductal and periampullary adenocarcinoma patients.

Molecular Medicine (Cambridge, Mass.)

G Saha, R Singh, A Mandal, S Das, E Chattopadhyay, P Panja, P Roy, N DeSarkar, S Gulati, S Ghatak, S Ghosh, S Banerjee, B Roy, S Ghosh, D Chaudhuri, N Arora, NK Biswas, N Sikdar

Publication Date: 2020-06-17

Variant appearance in text: N/A

PMID: 32552660

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Application of targeted next generation sequencing for the mutational profiling of patients with acute lymphoblastic leukemia.

Journal Of Medical Biochemistry

D Janic, J Peric, T Karan-Djurasevic, T Kostic, I Marjanovic, B Stanic, N Pejanovic, L Dokmanovic, J Lazic, N Krstovski, M Virijevic, D Tomin, A Vidovic, N Suvajdzic-Vukovic, S Pavlovic, N Tosic

Publication Date: 2020-01-10

Variant appearance in text: TP53: 215C>G; P72R; rs1042522

PMID: 32550823

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Case report for an adolescent with germline RET mutation and alveolar rhabdomyosarcoma.

Cold Spring Harbor Molecular Case Studies

KA Crawford, NE Berlow, J Tsay, M Lazich, M Mancini, C Noakes, T Huang, C Keller

Publication Date: 2020-06

Variant appearance in text: TP53: 215C>G; Pro72Arg; rs1042522

PMID: 32532875

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Association Analysis of TP53 rs1042522, MDM2 rs2279744, rs3730485, MDM4 rs4245739 Variants and Acute Myeloid Leukemia Susceptibility, Risk Stratification Scores, and Clinical Features: An Exploratory Study.

Journal Of Clinical Medicine

F Tripon, M Iancu, A Trifa, GA Crauciuc, A Boglis, B Balla, A Cosma, D Dima, M Candea, E Lazar, L Jimbu, C Banescu

Publication Date: 2020-06-01

Variant appearance in text: N/A

PMID: 32492903

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Unique insights from ClinicalTrials.gov by mining protein mutations and RSids in addition to applying the Human Phenotype Ontology.

Plos One

S Alag

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32459809

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TP53 rs1042522 polymorphism and early-onset breast cancer.

Journal Of Research In Medical Sciences : The Official Journal Of Isfahan University Of Medical Sciences

I Icen-Taskin, S Irtegun-Kandemir, O Munzuroglu

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32419782

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TP53 Arg72Pro polymorphism and neuroblastoma susceptibility in eastern Chinese children: a three-center case-control study.

Bioscience Reports

Y Fang, X Wu, L Li, J Zhu, H Wu, H Zhou, J He, Y Wang

Publication Date: 2020-05-14

Variant appearance in text: N/A

PMID: 32406493

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Adamantinomatous Craniopharyngioma in an Adult: A Case Report with NGS Analysis.

International Medical Case Reports Journal

RA Jastania, M Saeed, H Al-Khalidi, K AlQuthami, TH Nageeti, FA Al-Allaf, K Valerie, MM Taher

Publication Date: 2020

Variant appearance in text: TP53: 215C>G; Pro72Arg; rs1042522

PMID: 32368160

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Toxicity and Pharmacogenomic Biomarkers in Breast Cancer Chemotherapy.

Frontiers In Pharmacology

ZN Al-Mahayri, GP Patrinos, BR Ali

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32351390

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Genetic Polymorphisms as non-modifiable susceptibility factors to Laryngeal cancer.

Bioscience Reports

P Escalante, T Barría, M Cancino, M Rahal, L Cerpa, C Sandoval, S Molina, M Suárez, M Martínez, D Cáceres, LA Quiñones, NM Varela

Publication Date: 2020-04-27

Variant appearance in text: TP53: 215C>G; rs1042522

PMID: 32338278

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Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer.

Cell Death & Disease

A Ottaiano, L Circelli, A Lombardi, S Scala, N Martucci, J Galon, M Buonanno, G Scognamiglio, G Botti, F Hermitte, G Savarese, L D'Amore, F Tatangelo, A Di Mauro, G Liguori, AM Trotta, M Napolitano, M Capozzi, S Tafuto, F Perri, A La Rocca, M Caraglia, G Nasti

Publication Date: 2020-04-24

Variant appearance in text: TP53: Pro72Arg

PMID: 32332709

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Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas.

Aging

M Elshaer, AI ElManawy, A Hammad, A Namani, XJ Wang, X Tang

Publication Date: 2020-04-23

Variant appearance in text: N/A

PMID: 32327612

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Associations among smoking, MGMT hypermethylation, TP53-mutations, and relapse in head and neck squamous cell carcinoma.

Plos One

S Matsuda, A Mafune, N Kohda, T Hama, M Urashima

Publication Date: 2020

Variant appearance in text: TP53: P72R

PMID: 32324779

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Targeted next generation sequencing identifies somatic mutations in a cohort of Egyptian breast cancer patients.

Journal Of Advanced Research

A Nassar, M Abouelhoda, O Mansour, SA Loutfy, MM Hafez, M Gomaa, A Bahnassy, AS El-Din Youssef, MM Lotfy, H Ismail, OS Ahmed, AA Abou-Bakr, AN Zekri

Publication Date: 2020-07

Variant appearance in text: TP53: 215C>G; P72R

PMID: 32322420

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Germline mutation of MDM4, a major p53 regulator, in a familial syndrome of defective telomere maintenance.

Science Advances

E Toufektchan, V Lejour, R Durand, N Giri, I Draskovic, B Bardot, P Laplante, S Jaber, BP Alter, JA Londono-Vallejo, SA Savage, F Toledo

Publication Date: 2020-04

Variant appearance in text: N/A

PMID: 32300648

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Genetic Polymorphisms and Platinum-Based Chemotherapy-Induced Toxicities in Patients With Lung Cancer: A Systematic Review and Meta-Analysis.

Frontiers In Oncology

W Liu, Y Wang, J Luo, H Yuan, Z Luo

Publication Date: 2019

Variant appearance in text: N/A

PMID: 32257953

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Co-occurrence of PML-RARA gene fusion, chromosome 8 trisomy, and FLT3 ITD mutation in a young female patient with de novo acute myeloid leukemia and early death: A CARE case report.

Medicine

F Tripon, GA Crauciuc, A Bogliş, V Moldovan, J Sándor-Kéri, IJ Benedek, AP Trifa, C Bănescu

Publication Date: 2020-04

Variant appearance in text: TP53: 215C>G; rs1042522

PMID: 32243411

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Frequency of somatic mutations in TERT promoter, TP53 and CTNNB1 genes in patients with hepatocellular carcinoma from Southern Italy.

Oncology Letters

D Lombardo, C Saitta, D Giosa, FC Di Tocco, C Musolino, G Caminiti, V Chines, MS Franzè, A Alibrandi, G Navarra, G Raimondo, T Pollicino

Publication Date: 2020-03

Variant appearance in text: N/A

PMID: 32194736

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Jumping translocations of 1q in donor cell-derived myelodysplastic syndrome after cord blood transplantation: Case report and review of the literature.

Molecular And Clinical Oncology

T Kondo, T Tasaka, R Shimizu, K Hayashi, S Yamada, H Fukuda, T Hirose, A Takeuchi, F Sano, H Tokunaga, Y Matsuhashi, H Wada

Publication Date: 2020-04

Variant appearance in text: N/A

PMID: 32190321

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NOTCH3 T6746C and TP53 P72R Polymorphisms Are Associated with the Susceptibility to Diffuse Cutaneous Systemic Sclerosis.

Biomed Research International

S Zmorzyński, M Wojcierowska-Litwin, M Kowal, M Michalska-Jakubus, W Styk, AA Filip, I Walecka, D Krasowska

Publication Date: 2020

Variant appearance in text: TP53: P72R; rs1042522

PMID: 32185220

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A Multi-level Model to Understand Cervical Cancer Disparities in Appalachia.

Cancer Prevention Research (Philadelphia, Pa.)

ED Paskett, ML Pennell, MT Ruffin, CM Weghorst, B Lu, EM Hade, J Peng, BM Bernardo, ME Wewers

Publication Date: 2020-03

Variant appearance in text: N/A

PMID: 32132116

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Association of SNPs in CDKN2A (P14ARF) Tumour Suppressor Gene With Endometrial Cancer in Postmenopausal Women.

In Vivo (Athens, Greece)

W Wujcicka, A Zajac, K Szyllo, B Smolarz, H Romanowicz, G Stachowiak

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32111808

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Biomarkers in retinoblastoma.

International Journal Of Ophthalmology

J Sun, HY Xi, Q Shao, QH Liu

Publication Date: 2020

Variant appearance in text: N/A

PMID: 32090044

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The association of miR34b/c and TP53 gene polymorphisms with Wilms tumor risk in Chinese children.

Bioscience Reports

J Wang, S Lou, X Huang, Y Mo, Z Wang, J Zhu, X Tian, J Shi, H Zhou, J He, J Ruan

Publication Date: 2020-02-21

Variant appearance in text: N/A

PMID: 32083300

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Characterizations of Gene Alterations in Melanoma Patients from Chinese Population.

Biomed Research International

Y Luo, Z Zhang, J Liu, L Li, X Xu, X Yao, Z Dai, X Wang, S Yang, H Wu, J Bu, Y Wu, T Xiang, X Li

Publication Date: 2020

Variant appearance in text: TP53: P72R

PMID: 32083130

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Combined Effect of HPV and Several Gene SNPs in Laryngeal Cancer.

Medicina (Kaunas, Lithuania)

A Stumbrytė-Kaminskienė, Ž Gudlevičienė, D Dabkevičienė, I Mackevičienė

Publication Date: 2020-02-17

Variant appearance in text: N/A

PMID: 32079256

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An NRAS mutation in primary malignant melanoma of the lung: a case report.

Diagnostic Pathology

T Hibiya, M Tanaka, M Matsumura, A Aoki, T Ikegami, K Okudela, N Kawano, K Ohashi

Publication Date: 2020-02-07

Variant appearance in text: TP53: P72R

PMID: 32028967

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Synthetic Lethal Targeting of Mitotic Checkpoints in HPV-Negative Head and Neck Cancer.

Cancers

AY Deneka, MB Einarson, J Bennett, AS Nikonova, M Elmekawy, Y Zhou, JW Lee, BA Burtness, EA Golemis

Publication Date: 2020-01-28

Variant appearance in text: TP53: P72R

PMID: 32012873

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Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness.

Plos One

T Ahsan, NJ Urmi, AA Sajib

Publication Date: 2020

Variant appearance in text: N/A

PMID: 31971968

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Carcinosarcoma colliding osteosarcoma of the pancreas: a rare case report of multiple clonal originated pancreatic tumors.

International Journal Of Clinical And Experimental Pathology

X Zhou, M Li, P Wang, X Teng, L Sun, J Chen, Z Jia

Publication Date: 2018

Variant appearance in text: p53: 215C>G

PMID: 31938279

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Inter-laboratory proficiency testing scheme for tumour next-generation sequencing in Ontario: a pilot study.

Current Oncology (Toronto, Ont.)

T Spence, N Stickle, C Yu, H Chow, H Feilotter, B Lo, E McCready, B Sadikovic, LL Siu, PL Bedard, TL Stockley

Publication Date: 2019-12

Variant appearance in text: TP53: 215C>G; P72R

PMID: 31896942

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The role of myoglobin in epithelial cancers: Insights from transcriptomics.

International Journal Of Molecular Medicine

A Bicker, T Nauth, D Gerst, MA Aboouf, J Fandrey, G Kristiansen, TA Gorr, T Hankeln

Publication Date: 2019-12-18

Variant appearance in text: p53: Pro72Arg

PMID: 31894249

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Carcinogen Metabolism Pathway and Tumor Suppressor Gene Polymorphisms and Gallbladder Cancer Risk in North Indians: A Hospital-Based Case-Control Study.

Asian Pacific Journal Of Cancer Prevention : Apjcp

T Asai, Y Tsuchiya, K Mishra, A Behari, P Shukla, T Ikoma, VK Kapoor, K Nakamura

Publication Date: 2019-12-01

Variant appearance in text: N/A

PMID: 31870105

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Recommendations for the collection and use of multiplexed functional data for clinical variant interpretation.

Genome Medicine

H Gelman, JN Dines, J Berg, AH Berger, S Brnich, FM Hisama, RG James, AF Rubin, J Shendure, B Shirts, DM Fowler, LM Starita,

Publication Date: 2019-12-20

Variant appearance in text: TP53: Pro72Arg

PMID: 31862013

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Human papillomavirus type 18 oncoproteins exert their oncogenicity in esophageal and tongue squamous cell carcinoma cell lines distinctly.

Bmc Cancer

SS Boon, Z Chen, J Li, KYC Lee, L Cai, R Zhong, PKS Chan

Publication Date: 2019-12-12

Variant appearance in text: p53: P72R

PMID: 31830929

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Two Functional TP53 Genetic Variants and Predisposition to Keloid Scarring in Caucasians.

Dermatology Research And Practice

A Dmytrzak, A Boroń, B Łoniewska, K Lewandowska, I Gorący, M Kaczmarczyk, A Ciechanowicz

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31827503

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Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

Gut

Z Montazeri, X Li, C Nyiraneza, X Ma, M Timofeeva, V Svinti, X Meng, Y He, Y Bo, S Morgan, S Castellví-Bel, C Ruiz-Ponte, C Fernández-Rozadilla, Á Carracedo, A Castells, T Bishop, D Buchanan, MA Jenkins, TO Keku, A Lindblom, FJB van Duijnhoven, A Wu, SM Farrington, MG Dunlop, H Campbell, E Theodoratou, W Zheng, J Little

Publication Date: 2019-12-09

Variant appearance in text: N/A

PMID: 31818908

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The Role of Single-Nucleotide Polymorphisms in Pituitary Adenomas Tumorigenesis.

Cancers

SS Shah, MK Aghi

Publication Date: 2019-12-09

Variant appearance in text: N/A

PMID: 31818039

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KRAS and ERBB-family genetic alterations affect response to PD-1 inhibitors in metastatic nonsquamous NSCLC.

Therapeutic Advances In Medical Oncology

M Cinausero, N Laprovitera, G Maglio, L Gerratana, M Riefolo, M Macerelli, M Fiorentino, E Porcellini, V Buoro, F Gelsomino, A Squadrilli, G Fasola, M Negrini, M Tiseo, M Ferracin, A Ardizzoni

Publication Date: 2019

Variant appearance in text: TP53: P72R

PMID: 31798692

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p53 protein expression affected by TP53 polymorphism is associated with the biological behavior and prognosis of low rectal cancer.

Oncology Letters

G Zhang, Q Xu, Z Wang, L Sun, Z Lv, J Liu, C Xing, Y Yuan

Publication Date: 2019-12

Variant appearance in text: N/A

PMID: 31788124

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Mutational spectrum of tobacco associated oral squamous carcinoma and its therapeutic significance.

World Journal Of Surgical Oncology

N Batta, M Pandey

Publication Date: 2019-11-27

Variant appearance in text: TP53: 215C>G

PMID: 31775759

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The genetic association study of TP53 polymorphisms in Saudi obese patients.

Saudi Journal Of Biological Sciences

JSM Sabir, A El Omri, NA Shaik, B Banaganapalli, NH Hajrah, H Zrelli, L Arfaoui, ZA Awan, AM Shaikh Omar, A Mohammed, MG Alharbi, AM Alhebshi, RK Jansen, M Khan

Publication Date: 2019-11

Variant appearance in text: p53: Pro72Arg; rs1042522

PMID: 31762593

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P21 Ser31Arg and FGFR2 rs2981582 Polymorphisms as Risk Factors for Early Onset of Breast Cancer in Yogyakarta, Indonesia.

Asian Pacific Journal Of Cancer Prevention : Apjcp

D Purnomosari, C Raharjo, AS Kalim, R Herviastuti, M Yushan, RA Fajar, KK Harris, A Wahyono

Publication Date: 2019-11-01

Variant appearance in text: p53: Pro72Arg; rs1042522

PMID: 31759353

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New frontiers to cure Alport syndrome: COL4A3 and COL4A5 gene editing in podocyte-lineage cells.

European Journal Of Human Genetics : Ejhg

S Daga, F Donati, K Capitani, S Croci, R Tita, A Giliberti, F Valentino, E Benetti, C Fallerini, F Niccheri, M Baldassarri, MA Mencarelli, E Frullanti, S Furini, SG Conticello, A Renieri, AM Pinto

Publication Date: 2019-11-21

Variant appearance in text: p53: 215C>G

PMID: 31754267

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TP53 alterations in relapsed childhood acute lymphoblastic leukemia.

Cancer Science

CH Yu, WT Chang, ST Jou, TK Lin, YH Chang, CY Lin, KH Lin, MY Lu, SH Chen, KH Wu, SC Wang, HH Chang, YN Su, CC Hung, DT Lin, HY Chen, YL Yang

Publication Date: 2019-11-14

Variant appearance in text: TP53: P72R

PMID: 31729120

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Childhood adrenocortical tumor: A clinical and immunohistochemical study of 13 cases.

Medicine

X Wu, J Xu, J Wang, W Gu, C Zou

Publication Date: 2019-11

Variant appearance in text: TP53: Pro72Arg

PMID: 31725643

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The Dilemma of TP53 Codon 72 Polymorphism (rs1042522) and Breast Cancer Risk: A Case-Control Study and Meta-Analysis in The Iranian Population.

Cell Journal

F Afzaljavan, N Chaeichi Tehrani, M Rivandi, S Zarif Ghasemian, E Vahednia, R Khayami, M Abavisani, A Pasdar

Publication Date: 2020-07

Variant appearance in text: N/A

PMID: 31721533

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Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women.

Journal Of Biomedical Science

M Harati-Sadegh, L Kohan, B Teimoori, M Mehrabani, S Salimi

Publication Date: 2019-11-08

Variant appearance in text: TP53: P72R; rs1042522

PMID: 31703578

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Tissue-specific microRNA expression alters cancer susceptibility conferred by a TP53 noncoding variant.

Nature Communications

Q Deng, H Hu, X Yu, S Liu, L Wang, W Chen, C Zhang, Z Zeng, Y Cao, ZY Xu-Monette, L Li, M Zhang, S Rosenfeld, S Bao, E Hsi, KH Young, Z Lu, Y Li

Publication Date: 2019-11-07

Variant appearance in text: TP53: P72R

PMID: 31699989

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Nucleotide variations of TP53 exon 4 found in intracranial meningioma and in silico prediction of their significance.

Molecular And Clinical Oncology

A Bukovac, A Kafka, R Hrašćan, T Vladušić, N Pećina-Šlaus

Publication Date: 2019-12

Variant appearance in text: N/A

PMID: 31692929

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Landscape of Germline Mutations in DNA Repair Genes for Breast Cancer in Latin America: Opportunities for PARP-Like Inhibitors and Immunotherapy.

Genes

LK Urbina-Jara, A Rojas-Martinez, E Martinez-Ledesma, D Aguilar, C Villarreal-Garza, R Ortiz-Lopez

Publication Date: 2019-10-10

Variant appearance in text: TP53: 215C>G; rs1042522

PMID: 31658756

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Clinico-Pathological Characteristics and Mutational Analysis of Gastrointestinal Stromal Tumors from India: A Single Institution Experience.

Asian Pacific Journal Of Cancer Prevention : Apjcp

S Minhas, S Bhalla, M Jauhri, M Ganvir, S Aggarwal

Publication Date: 2019-10-01

Variant appearance in text: TP53: Pro72Arg

PMID: 31653154

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The complementary effect of rs1042522 in TP53 and rs1805007 in MC1R is associated with an elevated risk of cutaneous melanoma in Latvian population.

Oncology Letters

A Ozola, D Ruklisa, D Pjanova

Publication Date: 2019-11

Variant appearance in text: TP53: 215C>G; Pro72Arg; rs1042522

PMID: 31612033

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Clonal Evolution of TP53 c.375+1G>A Mutation in Pre- and Post- Neo-Adjuvant Chemotherapy (NACT) Tumor Samples in High-Grade Serous Ovarian Cancer (HGSOC).

Cells

M Garziera, E Cecchin, G Giorda, R Sorio, S Scalone, E De Mattia, R Roncato, S Gagno, E Poletto, L Romanato, F Ecca, V Canzonieri, G Toffoli

Publication Date: 2019-10-01

Variant appearance in text: TP53: 215C>G; rs1042522

PMID: 31581548

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DNA sequencing of cytopathologically inconclusive EUS-FNA from solid pancreatic lesions suspicious for malignancy confirms EUS diagnosis.

Endoscopic Ultrasound

JI Plougmann, P Klausen, A Toxvaerd, AA Abedi, B Kovacevic, JG Karstensen, TS Poulsen, E Kalaitzakis, E Høgdall, P Vilmann

Publication Date: 2019-09-25

Variant appearance in text: TP53: P72R

PMID: 31552911

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Correlation between Candidate Single Nucleotide Variants and Several Clinicopathological Risk Factors Related to Breast Cancer in Jordanian Women: A Genotype-Phenotype Study.

Journal Of Cancer

LN Al-Eitan, DM Rababa'h, MA Alghamdi, RH Khasawneh

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31528229

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Case report of rhabdomyosarcomatous transformation of a primary gastrointestinal stromal tumor (GIST).

Bmc Cancer

L Li, M Khalili, G Johannes, P Baratam, WF Morano, M Styler, WB Bowne, JS Hou

Publication Date: 2019-09-13

Variant appearance in text: TP53: Pro72Arg

PMID: 31514735

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Cancer Panel Assay for Precision Oncology Clinic: Results from a 1-Year Study.

Translational Oncology

D Kwon, B Kim, HC Shin, EJ Kim, SY Ha, KT Jang, ST Kim, J Lee, WK Kang, JO Park, KM Kim

Publication Date: 2019-11

Variant appearance in text: TP53: Pro72Arg

PMID: 31442744

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Haplotype and linkage disequilibrium of TP53-WRAP53 locus in Iranian-Azeri women with breast cancer.

Plos One

N Pouladi, S Abdolahi, D Farajzadeh, MA Hosseinpour Feizi

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31387111

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Germline and somatic mutations in patients with multiple primary melanomas: a next generation sequencing study.

Bmc Cancer

M Casula, P Paliogiannis, F Ayala, V De Giorgi, I Stanganelli, M Mandalà, M Colombino, A Manca, MC Sini, C Caracò, PA Ascierto, RR Satta, , A Lissia, A Cossu, G Palmieri,

Publication Date: 2019-08-05

Variant appearance in text: TP53: P72R

PMID: 31382929

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TP53 codon 72 polymorphism is associated with FGFR3 and RAS mutation in non-muscle-invasive bladder cancer.

Plos One

T Kawahara, T Kojima, S Kandori, M Kurobe, T Yoshino, T Kimura, Y Nagumo, R Ishituka, K Mitsuzuka, S Narita, T Kobayashi, Y Matsui, O Ogawa, M Sugimoto, J Miyazaki, H Nishiyama

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31369573

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Association of miR-34b/c rs4938723 and TP53 Arg72Pro Polymorphisms with Neuroblastoma Susceptibility: Evidence from Seven Centers.

Translational Oncology

L Li, J Zhu, T Lu, W Liu, J Tang, J Zhang, Y Wang, Y Li, S Li, H Zhou, H Xia, J He, J Cheng

Publication Date: 2019-10

Variant appearance in text: N/A

PMID: 31325764

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Gene Expression Analyses in Non Muscle Invasive Bladder Cancer Reveals a Role for Alternative Splicing and Tp53 Status.

Scientific Reports

M Dueñas, A Pérez-Figueroa, C Oliveira, C Suárez-Cabrera, A Sousa, P Oliveira, F Villacampa, JM Paramio, M Martínez-Fernández

Publication Date: 2019-07-17

Variant appearance in text: N/A

PMID: 31316092

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Association of the TP53 rs1042522 C>G polymorphism and hepatoblastoma risk in Chinese children.

Journal Of Cancer

T Yang, Y Wen, J Li, J Yang, T Tan, J Pan, C Hu, J Zhang, Y Xin, S Li, H Xia, J He, Y Zou

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31293648

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The 45th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians - Poster Session.

Bone Marrow Transplantation

.

Publication Date: 2019-07

Variant appearance in text: TP53: P72R

PMID: 31270396

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Establishment and characterization of patient-derived organoids from a young patient with cervical clear cell carcinoma.

Cancer Science

Y Maru, N Tanaka, K Ebisawa, A Odaka, T Sugiyama, M Itami, Y Hippo

Publication Date: 2019-09

Variant appearance in text: N/A

PMID: 31265190

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Phase 1b study of the MDM2 inhibitor AMG 232 with or without trametinib in relapsed/refractory acute myeloid leukemia.

Blood Advances

HP Erba, PS Becker, PJ Shami, MR Grunwald, DL Flesher, M Zhu, E Rasmussen, HA Henary, AA Anderson, ES Wang

Publication Date: 2019-07-09

Variant appearance in text: TP53: Pro72Arg

PMID: 31253596

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A case of biliary adenofibroma of the liver with malignant transformation: a morphomolecular case report and review of the literature.

Surgical Case Reports

AK Sturm, T Welsch, C Meissner, DE Aust, G Baretton

Publication Date: 2019-06-24

Variant appearance in text: TP53: 215C>G

PMID: 31236706

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Association between TP53 gene codon72 polymorphism and prostate cancer risk: A systematic review and meta-analysis.

Medicine

PZ Han, DH Cao, XL Zhang, ZJ Ren, Q Wei

Publication Date: 2019-06

Variant appearance in text: N/A

PMID: 31232967

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Molecular characterization of carcinosarcomas arising in the uterus and ovaries.

Oncotarget

M Brunetti, A Agostini, J Staurseth, B Davidson, S Heim, F Micci

Publication Date: 2019-06-04

Variant appearance in text: TP53: 215C>G

PMID: 31217897

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Laying the foundation for genomically-based risk assessment in chronic myeloid leukemia.

Leukemia

S Branford, DDH Kim, JF Apperley, CA Eide, S Mustjoki, ST Ong, G Nteliopoulos, T Ernst, C Chuah, C Gambacorti-Passerini, MJ Mauro, BJ Druker, DW Kim, FX Mahon, J Cortes, JP Radich, A Hochhaus, TP Hughes,

Publication Date: 2019-08

Variant appearance in text: TP53: 215C>G; Pro72Arg

PMID: 31209280

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Five P53 SNPs Involved in Low Rectal Cancer Risk and Prognosis in a Chinese Population.

Journal Of Cancer

G Zhang, Q Xu, J Liu, Z Lv, Y Lu, H Yang, L Sun, C Xing, Y Yuan

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31205533

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Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.

Cell Stem Cell

M Huang, J Tailor, Q Zhen, AH Gillmor, ML Miller, H Weishaupt, J Chen, T Zheng, EK Nash, LK McHenry, Z An, F Ye, Y Takashima, J Clarke, H Ayetey, FMG Cavalli, B Luu, BS Moriarity, S Ilkhanizadeh, L Chavez, C Yu, KM Kurian, T Magnaldo, N Sevenet, P Koch, SM Pollard, P Dirks, MP Snyder, DA Largaespada, YJ Cho, JJ Phillips, FJ Swartling, AS Morrissy, M Kool, SM Pfister, MD Taylor, A Smith, WA Weiss

Publication Date: 2019-09-05

Variant appearance in text: TP53: P72R; rs1042522

PMID: 31204176

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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy.

Cancer Cell

Y Fang, DJ McGrail, C Sun, M Labrie, X Chen, D Zhang, Z Ju, CP Vellano, Y Lu, Y Li, KJ Jeong, Z Ding, J Liang, SW Wang, H Dai, S Lee, N Sahni, I Mercado-Uribe, TB Kim, K Chen, SY Lin, G Peng, SN Westin, J Liu, MJ O'Connor, TA Yap, GB Mills

Publication Date: 2019-06-10

Variant appearance in text: TP53: P72R

PMID: 31185210

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Common genetic variants in the TP53 pathway and their impact on cancer.

Journal Of Molecular Cell Biology

T Barnoud, JLD Parris, ME Murphy

Publication Date: 2019-07-19

Variant appearance in text: p53: Pro72Arg; rs1042522

PMID: 31152665

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Establishment of Highly Transplantable Cholangiocarcinoma Cell Lines from a Patient-Derived Xenograft Mouse Model.

Cells

K Vaeteewoottacharn, C Pairojkul, R Kariya, K Muisuk, K Imtawil, Y Chamgramol, V Bhudhisawasdi, N Khuntikeo, A Pugkhem, OT Saeseow, A Silsirivanit, C Wongkham, S Wongkham, S Okada

Publication Date: 2019-05-23

Variant appearance in text: TP53: P72R

PMID: 31126020

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Esophageal cancer genetics in South Africa.

Clinical And Experimental Gastroenterology

M Alaouna, R Hull, C Penny, Z Dlamini

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31114287

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p53 polymorphism and association of human papillomavirus in oral submucous fibrosis and oral squamous cell carcinoma: A case-control study.

Journal Of Oral And Maxillofacial Pathology : Jomfp

K Hallikeri, K Burde, V Anehosur, BB Kulkarni, SV Hiremath

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31110424

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Polymorphisms of ADME-related genes and their implications for drug safety and efficacy in Amazonian Amerindians.

Scientific Reports

JCG Rodrigues, MR Fernandes, JF Guerreiro, ALDC da Silva, Â Ribeiro-Dos-Santos, S Santos, NPCD Santos

Publication Date: 2019-05-10

Variant appearance in text: N/A

PMID: 31076604

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Impact of MDM2, TP53 and P14ARF Polymorphisms on Endometrial Cancer Risk and Onset.

In Vivo (Athens, Greece)

W Wujcicka, A Zając, G Stachowiak

Publication Date: 2019

Variant appearance in text: N/A

PMID: 31028217

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miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma.

Molecular Therapy. Nucleic Acids

G Misso, MR Zarone, A Lombardi, A Grimaldi, AM Cossu, C Ferri, M Russo, DC Vuoso, A Luce, H Kawasaki, MT Di Martino, A Virgilio, A Festa, A Galeone, G De Rosa, C Irace, M Donadelli, A Necas, E Amler, P Tagliaferri, P Tassone, M Caraglia

Publication Date: 2019-06-07

Variant appearance in text: TP53: P72R

PMID: 31009917

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Defining the genetic profile of endometriosis.

Experimental And Therapeutic Medicine

L Vassilopoulou, M Matalliotakis, MI Zervou, C Matalliotaki, K Krithinakis, I Matalliotakis, DA Spandidos, GN Goulielmos

Publication Date: 2019-05

Variant appearance in text: N/A

PMID: 30988702

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New Chondrosarcoma Cell Lines with Preserved Stem Cell Properties to Study the Genomic Drift During In Vitro/In Vivo Growth.

Journal Of Clinical Medicine

V Rey, ST Menendez, O Estupiñan, A Rodriguez, L Santos, J Tornin, L Martinez-Cruzado, D Castillo, GR Ordoñez, S Costilla, C Alvarez-Fernandez, A Astudillo, A Braña, R Rodriguez

Publication Date: 2019-04-04

Variant appearance in text: TP53: P72R

PMID: 30987403

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Mechanistic insights into environmental and genetic risk factors for systemic lupus erythematosus.

American Journal Of Translational Research

Q Pan, J Chen, L Guo, X Lu, S Liao, C Zhao, S Wang, H Liu

Publication Date: 2019

Variant appearance in text: N/A

PMID: 30972159

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Genetic Susceptibility in Head and Neck Squamous Cell Carcinoma in a Spanish Population.

Cancers

J Fernández-Mateos, R Seijas-Tamayo, JC Adansa Klain, M Pastor Borgoñón, E Pérez-Ruiz, R Mesía, E Del Barco, C Salvador Coloma, A Rueda Dominguez, J Caballero Daroqui, E Fernández Ruiz, A Ocana, R González-Sarmiento, JJ Cruz-Hernández

Publication Date: 2019-04-07

Variant appearance in text: TP53: 215C>G; rs1042522

PMID: 30959967

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Alternative transcript annotations:

Transcript	cDNA	Protein	Consequence	Exon	Intron
ENST00000269305.4	c.215C>G	p.Pro72Arg	missense_variant	4/11	-
ENST00000359597.4	c.215C>G	p.Pro72Arg	missense_variant	3/9	-
ENST00000413465.2	c.215C>G	p.Pro72Arg	missense_variant	3/7	-
ENST00000420246.2	c.215C>G	p.Pro72Arg	missense_variant	4/12	-
ENST00000445888.2	c.215C>G	p.Pro72Arg	missense_variant	4/11	-
ENST00000455263.2	c.215C>G	p.Pro72Arg	missense_variant	4/12	-
ENST00000503591.1	c.215C>G	p.Pro72Arg	missense_variant	5/6	-
ENST00000505014.1	n.471C>G	-	non_coding_transcript_exon_variant	3/5	-
ENST00000508793.1	c.215C>G	p.Pro72Arg	missense_variant	4/5	-
ENST00000509690.1	c.-21-918C>G	-	intron_variant	-	1/5
ENST00000514944.1	c.96+228C>G	-	intron_variant	-	3/5
ENST00000604348.1	c.215C>G	p.Pro72Arg	missense_variant	4/5	-
NM_000546.5	c.215C>G	p.Pro72Arg	missense_variant	4/11	-
NM_001126112.2	c.215C>G	p.Pro72Arg	missense_variant	4/11	-
NM_001126113.2	c.215C>G	p.Pro72Arg	missense_variant	4/12	-
NM_001126114.2	c.215C>G	p.Pro72Arg	missense_variant	4/12	-
NM_001126118.1	c.98C>G	p.Pro33Arg	missense_variant	3/10	-
NM_001276695.2	c.98C>G	p.Pro33Arg	missense_variant	4/12	-
NM_001276696.2	c.98C>G	p.Pro33Arg	missense_variant	4/12	-
NM_001276760.2	c.98C>G	p.Pro33Arg	missense_variant	4/11	-
NM_001276761.2	c.98C>G	p.Pro33Arg	missense_variant	4/11	-