Variant ID: 17-7579472-G-C

NM_000546.5(TP53):c.215C>G;(p.Pro72Arg)

This variant was identified in 636 publications




Publications:


Molecular Bases of Mechanisms Accounting for Drug Resistance in Gastric Adenocarcinoma.

Cancers
JJG Marin, L Perez-Silva, RIR Macias, M Asensio, A Peleteiro-Vigil, A Sanchez-Martin, C Cives-Losada, P Sanchon-Sanchez, B Sanchez De Blas, E Herraez, O Briz, E Lozano
Publication Date: 2020-07-30

Variant appearance in text: N/A
PMID: 32751679
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Both p53 codon 72 Arg/Arg and pro/Arg genotypes in glioblastoma multiforme are associated with a better prognosis in bevacizumab treatment.

Bmc Cancer
CC Shen, WY Cheng, CH Lee, XJ Dai, MT Chiao, YJ Liang, WY Hsieh, TF Mao, GS Lin, SR Chen, BS Liu, JP Chen
Publication Date: 2020-07-29

Variant appearance in text: N/A
PMID: 32727419
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High-Throughput Sequencing of Gastric Cancer Patients: Unravelling Genetic Predispositions Towards an Early-Onset Subtype.

Cancers
J Machlowska, P Kapusta, J Baj, FHM Morsink, P Wołkow, R Maciejewski, GJA Offerhaus, R Sitarz
Publication Date: 2020-07-21

Variant appearance in text: N/A
PMID: 32708070
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Plasma circulating tumor DNA assessment reveals KMT2D as a potential poor prognostic factor in extranodal NK/T-cell lymphoma.

Biomarker Research
Q Li, W Zhang, J Li, J Xiong, J Liu, T Chen, Q Wen, Y Zeng, L Gao, L Gao, C Zhang, P Kong, X Peng, Y Liu, X Zhang, J Rao
Publication Date: 2020

Variant appearance in text: TP53: P72R
PMID: 32695399
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Somatic Mutation Profiling in Premalignant Lesions of Vulvar Squamous Cell Carcinoma.

International Journal Of Molecular Sciences
S Zięba, AW Pouwer, A Kowalik, K Zalewski, N Rusetska, E Bakuła-Zalewska, J Kopczyński, JMA Pijnenborg, JA de Hullu, M Kowalewska
Publication Date: 2020-07-10

Variant appearance in text: TP53: P72R
PMID: 32664330
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Novel Genetic Variations in Acute Myeloid Leukemia in Pakistani Population.

Frontiers In Genetics
S Shahid, M Shakeel, S Siddiqui, S Ahmed, M Sohail, IA Khan, A Abid, T Shamsi
Publication Date: 2020

Variant appearance in text: N/A
PMID: 32655615
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Beyond the HLA polymorphism: A complex pattern of genetic susceptibility to pemphigus.

Genetics And Molecular Biology
ML Petzl-Erler
Publication Date: 2020

Variant appearance in text: N/A
PMID: 32639508
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XAF1 as a modifier of p53 function and cancer susceptibility.

Science Advances
EM Pinto, BC Figueiredo, W Chen, HCR Galvao, MN Formiga, MCBV Fragoso, P Ashton-Prolla, EMSF Ribeiro, G Felix, TEB Costa, SA Savage, M Yeager, EI Palmero, S Volc, H Salvador, JL Fuster-Soler, C Lavarino, G Chantada, D Vaur, V Odone-Filho, L Brugières, T Else, EM Stoffel, KN Maxwell, MI Achatz, L Kowalski, KC de Andrade, A Pappo, E Letouze, AC Latronico, BB Mendonca, MQ Almeida, VB Brondani, CM Bittar, EWS Soares, C Mathias, CRN Ramos, M Machado, W Zhou, K Jones, A Vogt, PP Klincha, KM Santiago, H Komechen, MM Paraizo, IZS Parise, KV Hamilton, J Wang, E Rampersaud, MR Clay, AJ Murphy, E Lalli, KE Nichols, RC Ribeiro, C Rodriguez-Galindo, M Korbonits, J Zhang, MG Thomas, JP Connelly, S Pruett-Miller, Y Diekmann, G Neale, G Wu, GP Zambetti
Publication Date: 2020-06

Variant appearance in text: N/A
PMID: 32637605
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Pharmacogenomics and Pharmacogenetics in Osteosarcoma: Translational Studies and Clinical Impact.

International Journal Of Molecular Sciences
CM Hattinger, MP Patrizio, S Luppi, M Serra
Publication Date: 2020-06-30

Variant appearance in text: N/A
PMID: 32629971
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Mutation profiling of anaplastic ependymoma grade III by Ion Proton next generation DNA sequencing.

F1000Research
E Butt, S Alyami, T Nageeti, M Saeed, K AlQuthami, A Bouazzaoui, M Athar, Z Abduljaleel, F Al-Allaf, M Taher
Publication Date: 2019

Variant appearance in text: TP53: 215C>G; Pro72Arg; rs1042522
PMID: 32612806
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Single Nucleotide Variants Associated with Colorectal Cancer Among Iranian Patients: A Narrative Review.

Pharmacogenomics And Personalized Medicine
M Jamshidi, S Mohammadi Pour, MR Mahmoudian-Sani
Publication Date: 2020

Variant appearance in text: N/A
PMID: 32581566
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Ex vivo modelling of drug efficacy in a rare metastatic urachal carcinoma.

Bmc Cancer
R Mäkelä, A Arjonen, V Härmä, N Rintanen, L Paasonen, T Paprotka, K Rönsch, T Kuopio, J Kononen, JK Rantala
Publication Date: 2020-06-23

Variant appearance in text: TP53: P72R
PMID: 32576176
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A novel hotspot and rare somatic mutation p.A138V, at TP53 is associated with poor survival of pancreatic ductal and periampullary adenocarcinoma patients.

Molecular Medicine (Cambridge, Mass.)
G Saha, R Singh, A Mandal, S Das, E Chattopadhyay, P Panja, P Roy, N DeSarkar, S Gulati, S Ghatak, S Ghosh, S Banerjee, B Roy, S Ghosh, D Chaudhuri, N Arora, NK Biswas, N Sikdar
Publication Date: 2020-06-17

Variant appearance in text: N/A
PMID: 32552660
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Application of targeted next generation sequencing for the mutational profiling of patients with acute lymphoblastic leukemia.

Journal Of Medical Biochemistry
D Janic, J Peric, T Karan-Djurasevic, T Kostic, I Marjanovic, B Stanic, N Pejanovic, L Dokmanovic, J Lazic, N Krstovski, M Virijevic, D Tomin, A Vidovic, N Suvajdzic-Vukovic, S Pavlovic, N Tosic
Publication Date: 2020-01-10

Variant appearance in text: TP53: 215C>G; P72R; rs1042522
PMID: 32550823
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Case report for an adolescent with germline RET mutation and alveolar rhabdomyosarcoma.

Cold Spring Harbor Molecular Case Studies
KA Crawford, NE Berlow, J Tsay, M Lazich, M Mancini, C Noakes, T Huang, C Keller
Publication Date: 2020-06

Variant appearance in text: TP53: 215C>G; Pro72Arg; rs1042522
PMID: 32532875
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Association Analysis of TP53 rs1042522, MDM2 rs2279744, rs3730485, MDM4 rs4245739 Variants and Acute Myeloid Leukemia Susceptibility, Risk Stratification Scores, and Clinical Features: An Exploratory Study.

Journal Of Clinical Medicine
F Tripon, M Iancu, A Trifa, GA Crauciuc, A Boglis, B Balla, A Cosma, D Dima, M Candea, E Lazar, L Jimbu, C Banescu
Publication Date: 2020-06-01

Variant appearance in text: N/A
PMID: 32492903
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Unique insights from ClinicalTrials.gov by mining protein mutations and RSids in addition to applying the Human Phenotype Ontology.

Plos One
S Alag
Publication Date: 2020

Variant appearance in text: N/A
PMID: 32459809
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TP53 rs1042522 polymorphism and early-onset breast cancer.

Journal Of Research In Medical Sciences : The Official Journal Of Isfahan University Of Medical Sciences
I Icen-Taskin, S Irtegun-Kandemir, O Munzuroglu
Publication Date: 2020

Variant appearance in text: N/A
PMID: 32419782
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TP53 Arg72Pro polymorphism and neuroblastoma susceptibility in eastern Chinese children: a three-center case-control study.

Bioscience Reports
Y Fang, X Wu, L Li, J Zhu, H Wu, H Zhou, J He, Y Wang
Publication Date: 2020-05-14

Variant appearance in text: N/A
PMID: 32406493
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Adamantinomatous Craniopharyngioma in an Adult: A Case Report with NGS Analysis.

International Medical Case Reports Journal
RA Jastania, M Saeed, H Al-Khalidi, K AlQuthami, TH Nageeti, FA Al-Allaf, K Valerie, MM Taher
Publication Date: 2020

Variant appearance in text: TP53: 215C>G; Pro72Arg; rs1042522
PMID: 32368160
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Toxicity and Pharmacogenomic Biomarkers in Breast Cancer Chemotherapy.

Frontiers In Pharmacology
ZN Al-Mahayri, GP Patrinos, BR Ali
Publication Date: 2020

Variant appearance in text: N/A
PMID: 32351390
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Genetic Polymorphisms as non-modifiable susceptibility factors to Laryngeal cancer.

Bioscience Reports
P Escalante, T Barría, M Cancino, M Rahal, L Cerpa, C Sandoval, S Molina, M Suárez, M Martínez, D Cáceres, LA Quiñones, NM Varela
Publication Date: 2020-04-27

Variant appearance in text: TP53: 215C>G; rs1042522
PMID: 32338278
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Genetic trajectory and immune microenvironment of lung-specific oligometastatic colorectal cancer.

Cell Death & Disease
A Ottaiano, L Circelli, A Lombardi, S Scala, N Martucci, J Galon, M Buonanno, G Scognamiglio, G Botti, F Hermitte, G Savarese, L D'Amore, F Tatangelo, A Di Mauro, G Liguori, AM Trotta, M Napolitano, M Capozzi, S Tafuto, F Perri, A La Rocca, M Caraglia, G Nasti
Publication Date: 2020-04-24

Variant appearance in text: TP53: Pro72Arg
PMID: 32332709
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Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas.

Aging
M Elshaer, AI ElManawy, A Hammad, A Namani, XJ Wang, X Tang
Publication Date: 2020-04-23

Variant appearance in text: N/A
PMID: 32327612
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Associations among smoking, MGMT hypermethylation, TP53-mutations, and relapse in head and neck squamous cell carcinoma.

Plos One
S Matsuda, A Mafune, N Kohda, T Hama, M Urashima
Publication Date: 2020

Variant appearance in text: TP53: P72R
PMID: 32324779
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Targeted next generation sequencing identifies somatic mutations in a cohort of Egyptian breast cancer patients.

Journal Of Advanced Research
A Nassar, M Abouelhoda, O Mansour, SA Loutfy, MM Hafez, M Gomaa, A Bahnassy, AS El-Din Youssef, MM Lotfy, H Ismail, OS Ahmed, AA Abou-Bakr, AN Zekri
Publication Date: 2020-07

Variant appearance in text: TP53: 215C>G; P72R
PMID: 32322420
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Germline mutation of MDM4, a major p53 regulator, in a familial syndrome of defective telomere maintenance.

Science Advances
E Toufektchan, V Lejour, R Durand, N Giri, I Draskovic, B Bardot, P Laplante, S Jaber, BP Alter, JA Londono-Vallejo, SA Savage, F Toledo
Publication Date: 2020-04

Variant appearance in text: N/A
PMID: 32300648
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Genetic Polymorphisms and Platinum-Based Chemotherapy-Induced Toxicities in Patients With Lung Cancer: A Systematic Review and Meta-Analysis.

Frontiers In Oncology
W Liu, Y Wang, J Luo, H Yuan, Z Luo
Publication Date: 2019

Variant appearance in text: N/A
PMID: 32257953
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Co-occurrence of PML-RARA gene fusion, chromosome 8 trisomy, and FLT3 ITD mutation in a young female patient with de novo acute myeloid leukemia and early death: A CARE case report.

Medicine
F Tripon, GA Crauciuc, A Bogliş, V Moldovan, J Sándor-Kéri, IJ Benedek, AP Trifa, C Bănescu
Publication Date: 2020-04

Variant appearance in text: TP53: 215C>G; rs1042522
PMID: 32243411
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Frequency of somatic mutations in TERT promoter, TP53 and CTNNB1 genes in patients with hepatocellular carcinoma from Southern Italy.

Oncology Letters
D Lombardo, C Saitta, D Giosa, FC Di Tocco, C Musolino, G Caminiti, V Chines, MS Franzè, A Alibrandi, G Navarra, G Raimondo, T Pollicino
Publication Date: 2020-03

Variant appearance in text: N/A
PMID: 32194736
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Jumping translocations of 1q in donor cell-derived myelodysplastic syndrome after cord blood transplantation: Case report and review of the literature.

Molecular And Clinical Oncology
T Kondo, T Tasaka, R Shimizu, K Hayashi, S Yamada, H Fukuda, T Hirose, A Takeuchi, F Sano, H Tokunaga, Y Matsuhashi, H Wada
Publication Date: 2020-04

Variant appearance in text: N/A
PMID: 32190321
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NOTCH3 T6746C and TP53 P72R Polymorphisms Are Associated with the Susceptibility to Diffuse Cutaneous Systemic Sclerosis.

Biomed Research International
S Zmorzyński, M Wojcierowska-Litwin, M Kowal, M Michalska-Jakubus, W Styk, AA Filip, I Walecka, D Krasowska
Publication Date: 2020

Variant appearance in text: TP53: P72R; rs1042522
PMID: 32185220
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A Multi-level Model to Understand Cervical Cancer Disparities in Appalachia.

Cancer Prevention Research (Philadelphia, Pa.)
ED Paskett, ML Pennell, MT Ruffin, CM Weghorst, B Lu, EM Hade, J Peng, BM Bernardo, ME Wewers
Publication Date: 2020-03

Variant appearance in text: N/A
PMID: 32132116
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Association of SNPs in CDKN2A (P14ARF) Tumour Suppressor Gene With Endometrial Cancer in Postmenopausal Women.

In Vivo (Athens, Greece)
W Wujcicka, A Zajac, K Szyllo, B Smolarz, H Romanowicz, G Stachowiak
Publication Date: 2020

Variant appearance in text: N/A
PMID: 32111808
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Biomarkers in retinoblastoma.

International Journal Of Ophthalmology
J Sun, HY Xi, Q Shao, QH Liu
Publication Date: 2020

Variant appearance in text: N/A
PMID: 32090044
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The association of miR34b/c and TP53 gene polymorphisms with Wilms tumor risk in Chinese children.

Bioscience Reports
J Wang, S Lou, X Huang, Y Mo, Z Wang, J Zhu, X Tian, J Shi, H Zhou, J He, J Ruan
Publication Date: 2020-02-21

Variant appearance in text: N/A
PMID: 32083300
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Characterizations of Gene Alterations in Melanoma Patients from Chinese Population.

Biomed Research International
Y Luo, Z Zhang, J Liu, L Li, X Xu, X Yao, Z Dai, X Wang, S Yang, H Wu, J Bu, Y Wu, T Xiang, X Li
Publication Date: 2020

Variant appearance in text: TP53: P72R
PMID: 32083130
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Combined Effect of HPV and Several Gene SNPs in Laryngeal Cancer.

Medicina (Kaunas, Lithuania)
A Stumbrytė-Kaminskienė, Ž Gudlevičienė, D Dabkevičienė, I Mackevičienė
Publication Date: 2020-02-17

Variant appearance in text: N/A
PMID: 32079256
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An NRAS mutation in primary malignant melanoma of the lung: a case report.

Diagnostic Pathology
T Hibiya, M Tanaka, M Matsumura, A Aoki, T Ikegami, K Okudela, N Kawano, K Ohashi
Publication Date: 2020-02-07

Variant appearance in text: TP53: P72R
PMID: 32028967
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Synthetic Lethal Targeting of Mitotic Checkpoints in HPV-Negative Head and Neck Cancer.

Cancers
AY Deneka, MB Einarson, J Bennett, AS Nikonova, M Elmekawy, Y Zhou, JW Lee, BA Burtness, EA Golemis
Publication Date: 2020-01-28

Variant appearance in text: TP53: P72R
PMID: 32012873
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Heterogeneity in the distribution of 159 drug-response related SNPs in world populations and their genetic relatedness.

Plos One
T Ahsan, NJ Urmi, AA Sajib
Publication Date: 2020

Variant appearance in text: N/A
PMID: 31971968
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Carcinosarcoma colliding osteosarcoma of the pancreas: a rare case report of multiple clonal originated pancreatic tumors.

International Journal Of Clinical And Experimental Pathology
X Zhou, M Li, P Wang, X Teng, L Sun, J Chen, Z Jia
Publication Date: 2018

Variant appearance in text: p53: 215C>G
PMID: 31938279
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Inter-laboratory proficiency testing scheme for tumour next-generation sequencing in Ontario: a pilot study.

Current Oncology (Toronto, Ont.)
T Spence, N Stickle, C Yu, H Chow, H Feilotter, B Lo, E McCready, B Sadikovic, LL Siu, PL Bedard, TL Stockley
Publication Date: 2019-12

Variant appearance in text: TP53: 215C>G; P72R
PMID: 31896942
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The role of myoglobin in epithelial cancers: Insights from transcriptomics.

International Journal Of Molecular Medicine
A Bicker, T Nauth, D Gerst, MA Aboouf, J Fandrey, G Kristiansen, TA Gorr, T Hankeln
Publication Date: 2019-12-18

Variant appearance in text: p53: Pro72Arg
PMID: 31894249
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Carcinogen Metabolism Pathway and Tumor Suppressor Gene Polymorphisms and Gallbladder Cancer Risk in North Indians: A Hospital-Based Case-Control Study.

Asian Pacific Journal Of Cancer Prevention : Apjcp
T Asai, Y Tsuchiya, K Mishra, A Behari, P Shukla, T Ikoma, VK Kapoor, K Nakamura
Publication Date: 2019-12-01

Variant appearance in text: N/A
PMID: 31870105
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Recommendations for the collection and use of multiplexed functional data for clinical variant interpretation.

Genome Medicine
H Gelman, JN Dines, J Berg, AH Berger, S Brnich, FM Hisama, RG James, AF Rubin, J Shendure, B Shirts, DM Fowler, LM Starita,
Publication Date: 2019-12-20

Variant appearance in text: TP53: Pro72Arg
PMID: 31862013
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Human papillomavirus type 18 oncoproteins exert their oncogenicity in esophageal and tongue squamous cell carcinoma cell lines distinctly.

Bmc Cancer
SS Boon, Z Chen, J Li, KYC Lee, L Cai, R Zhong, PKS Chan
Publication Date: 2019-12-12

Variant appearance in text: p53: P72R
PMID: 31830929
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Two Functional TP53 Genetic Variants and Predisposition to Keloid Scarring in Caucasians.

Dermatology Research And Practice
A Dmytrzak, A Boroń, B Łoniewska, K Lewandowska, I Gorący, M Kaczmarczyk, A Ciechanowicz
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31827503
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Systematic meta-analyses, field synopsis and global assessment of the evidence of genetic association studies in colorectal cancer.

Gut
Z Montazeri, X Li, C Nyiraneza, X Ma, M Timofeeva, V Svinti, X Meng, Y He, Y Bo, S Morgan, S Castellví-Bel, C Ruiz-Ponte, C Fernández-Rozadilla, Á Carracedo, A Castells, T Bishop, D Buchanan, MA Jenkins, TO Keku, A Lindblom, FJB van Duijnhoven, A Wu, SM Farrington, MG Dunlop, H Campbell, E Theodoratou, W Zheng, J Little
Publication Date: 2019-12-09

Variant appearance in text: N/A
PMID: 31818908
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The Role of Single-Nucleotide Polymorphisms in Pituitary Adenomas Tumorigenesis.

Cancers
SS Shah, MK Aghi
Publication Date: 2019-12-09

Variant appearance in text: N/A
PMID: 31818039
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KRAS and ERBB-family genetic alterations affect response to PD-1 inhibitors in metastatic nonsquamous NSCLC.

Therapeutic Advances In Medical Oncology
M Cinausero, N Laprovitera, G Maglio, L Gerratana, M Riefolo, M Macerelli, M Fiorentino, E Porcellini, V Buoro, F Gelsomino, A Squadrilli, G Fasola, M Negrini, M Tiseo, M Ferracin, A Ardizzoni
Publication Date: 2019

Variant appearance in text: TP53: P72R
PMID: 31798692
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p53 protein expression affected by TP53 polymorphism is associated with the biological behavior and prognosis of low rectal cancer.

Oncology Letters
G Zhang, Q Xu, Z Wang, L Sun, Z Lv, J Liu, C Xing, Y Yuan
Publication Date: 2019-12

Variant appearance in text: N/A
PMID: 31788124
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Mutational spectrum of tobacco associated oral squamous carcinoma and its therapeutic significance.

World Journal Of Surgical Oncology
N Batta, M Pandey
Publication Date: 2019-11-27

Variant appearance in text: TP53: 215C>G
PMID: 31775759
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The genetic association study of TP53 polymorphisms in Saudi obese patients.

Saudi Journal Of Biological Sciences
JSM Sabir, A El Omri, NA Shaik, B Banaganapalli, NH Hajrah, H Zrelli, L Arfaoui, ZA Awan, AM Shaikh Omar, A Mohammed, MG Alharbi, AM Alhebshi, RK Jansen, M Khan
Publication Date: 2019-11

Variant appearance in text: p53: Pro72Arg; rs1042522
PMID: 31762593
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P21 Ser31Arg and FGFR2 rs2981582 Polymorphisms as Risk Factors for Early Onset of Breast Cancer in Yogyakarta, Indonesia.

Asian Pacific Journal Of Cancer Prevention : Apjcp
D Purnomosari, C Raharjo, AS Kalim, R Herviastuti, M Yushan, RA Fajar, KK Harris, A Wahyono
Publication Date: 2019-11-01

Variant appearance in text: p53: Pro72Arg; rs1042522
PMID: 31759353
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New frontiers to cure Alport syndrome: COL4A3 and COL4A5 gene editing in podocyte-lineage cells.

European Journal Of Human Genetics : Ejhg
S Daga, F Donati, K Capitani, S Croci, R Tita, A Giliberti, F Valentino, E Benetti, C Fallerini, F Niccheri, M Baldassarri, MA Mencarelli, E Frullanti, S Furini, SG Conticello, A Renieri, AM Pinto
Publication Date: 2019-11-21

Variant appearance in text: p53: 215C>G
PMID: 31754267
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TP53 alterations in relapsed childhood acute lymphoblastic leukemia.

Cancer Science
CH Yu, WT Chang, ST Jou, TK Lin, YH Chang, CY Lin, KH Lin, MY Lu, SH Chen, KH Wu, SC Wang, HH Chang, YN Su, CC Hung, DT Lin, HY Chen, YL Yang
Publication Date: 2019-11-14

Variant appearance in text: TP53: P72R
PMID: 31729120
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Childhood adrenocortical tumor: A clinical and immunohistochemical study of 13 cases.

Medicine
X Wu, J Xu, J Wang, W Gu, C Zou
Publication Date: 2019-11

Variant appearance in text: TP53: Pro72Arg
PMID: 31725643
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The Dilemma of TP53 Codon 72 Polymorphism (rs1042522) and Breast Cancer Risk: A Case-Control Study and Meta-Analysis in The Iranian Population.

Cell Journal
F Afzaljavan, N Chaeichi Tehrani, M Rivandi, S Zarif Ghasemian, E Vahednia, R Khayami, M Abavisani, A Pasdar
Publication Date: 2020-07

Variant appearance in text: N/A
PMID: 31721533
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Analysis of polymorphisms, promoter methylation, and mRNA expression profile of maternal and placental P53 and P21 genes in preeclamptic and normotensive pregnant women.

Journal Of Biomedical Science
M Harati-Sadegh, L Kohan, B Teimoori, M Mehrabani, S Salimi
Publication Date: 2019-11-08

Variant appearance in text: TP53: P72R; rs1042522
PMID: 31703578
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Tissue-specific microRNA expression alters cancer susceptibility conferred by a TP53 noncoding variant.

Nature Communications
Q Deng, H Hu, X Yu, S Liu, L Wang, W Chen, C Zhang, Z Zeng, Y Cao, ZY Xu-Monette, L Li, M Zhang, S Rosenfeld, S Bao, E Hsi, KH Young, Z Lu, Y Li
Publication Date: 2019-11-07

Variant appearance in text: TP53: P72R
PMID: 31699989
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Nucleotide variations of TP53 exon 4 found in intracranial meningioma and in silico prediction of their significance.

Molecular And Clinical Oncology
A Bukovac, A Kafka, R Hrašćan, T Vladušić, N Pećina-Šlaus
Publication Date: 2019-12

Variant appearance in text: N/A
PMID: 31692929
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Landscape of Germline Mutations in DNA Repair Genes for Breast Cancer in Latin America: Opportunities for PARP-Like Inhibitors and Immunotherapy.

Genes
LK Urbina-Jara, A Rojas-Martinez, E Martinez-Ledesma, D Aguilar, C Villarreal-Garza, R Ortiz-Lopez
Publication Date: 2019-10-10

Variant appearance in text: TP53: 215C>G; rs1042522
PMID: 31658756
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Clinico-Pathological Characteristics and Mutational Analysis of Gastrointestinal Stromal Tumors from India: A Single Institution Experience.

Asian Pacific Journal Of Cancer Prevention : Apjcp
S Minhas, S Bhalla, M Jauhri, M Ganvir, S Aggarwal
Publication Date: 2019-10-01

Variant appearance in text: TP53: Pro72Arg
PMID: 31653154
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The complementary effect of rs1042522 in TP53 and rs1805007 in MC1R is associated with an elevated risk of cutaneous melanoma in Latvian population.

Oncology Letters
A Ozola, D Ruklisa, D Pjanova
Publication Date: 2019-11

Variant appearance in text: TP53: 215C>G; Pro72Arg; rs1042522
PMID: 31612033
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Clonal Evolution of TP53 c.375+1G>A Mutation in Pre- and Post- Neo-Adjuvant Chemotherapy (NACT) Tumor Samples in High-Grade Serous Ovarian Cancer (HGSOC).

Cells
M Garziera, E Cecchin, G Giorda, R Sorio, S Scalone, E De Mattia, R Roncato, S Gagno, E Poletto, L Romanato, F Ecca, V Canzonieri, G Toffoli
Publication Date: 2019-10-01

Variant appearance in text: TP53: 215C>G; rs1042522
PMID: 31581548
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DNA sequencing of cytopathologically inconclusive EUS-FNA from solid pancreatic lesions suspicious for malignancy confirms EUS diagnosis.

Endoscopic Ultrasound
JI Plougmann, P Klausen, A Toxvaerd, AA Abedi, B Kovacevic, JG Karstensen, TS Poulsen, E Kalaitzakis, E Høgdall, P Vilmann
Publication Date: 2019-09-25

Variant appearance in text: TP53: P72R
PMID: 31552911
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Correlation between Candidate Single Nucleotide Variants and Several Clinicopathological Risk Factors Related to Breast Cancer in Jordanian Women: A Genotype-Phenotype Study.

Journal Of Cancer
LN Al-Eitan, DM Rababa'h, MA Alghamdi, RH Khasawneh
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31528229
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Case report of rhabdomyosarcomatous transformation of a primary gastrointestinal stromal tumor (GIST).

Bmc Cancer
L Li, M Khalili, G Johannes, P Baratam, WF Morano, M Styler, WB Bowne, JS Hou
Publication Date: 2019-09-13

Variant appearance in text: TP53: Pro72Arg
PMID: 31514735
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Cancer Panel Assay for Precision Oncology Clinic: Results from a 1-Year Study.

Translational Oncology
D Kwon, B Kim, HC Shin, EJ Kim, SY Ha, KT Jang, ST Kim, J Lee, WK Kang, JO Park, KM Kim
Publication Date: 2019-11

Variant appearance in text: TP53: Pro72Arg
PMID: 31442744
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Haplotype and linkage disequilibrium of TP53-WRAP53 locus in Iranian-Azeri women with breast cancer.

Plos One
N Pouladi, S Abdolahi, D Farajzadeh, MA Hosseinpour Feizi
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31387111
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Germline and somatic mutations in patients with multiple primary melanomas: a next generation sequencing study.

Bmc Cancer
M Casula, P Paliogiannis, F Ayala, V De Giorgi, I Stanganelli, M Mandalà, M Colombino, A Manca, MC Sini, C Caracò, PA Ascierto, RR Satta, , A Lissia, A Cossu, G Palmieri,
Publication Date: 2019-08-05

Variant appearance in text: TP53: P72R
PMID: 31382929
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TP53 codon 72 polymorphism is associated with FGFR3 and RAS mutation in non-muscle-invasive bladder cancer.

Plos One
T Kawahara, T Kojima, S Kandori, M Kurobe, T Yoshino, T Kimura, Y Nagumo, R Ishituka, K Mitsuzuka, S Narita, T Kobayashi, Y Matsui, O Ogawa, M Sugimoto, J Miyazaki, H Nishiyama
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31369573
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Association of miR-34b/c rs4938723 and TP53 Arg72Pro Polymorphisms with Neuroblastoma Susceptibility: Evidence from Seven Centers.

Translational Oncology
L Li, J Zhu, T Lu, W Liu, J Tang, J Zhang, Y Wang, Y Li, S Li, H Zhou, H Xia, J He, J Cheng
Publication Date: 2019-10

Variant appearance in text: N/A
PMID: 31325764
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Gene Expression Analyses in Non Muscle Invasive Bladder Cancer Reveals a Role for Alternative Splicing and Tp53 Status.

Scientific Reports
M Dueñas, A Pérez-Figueroa, C Oliveira, C Suárez-Cabrera, A Sousa, P Oliveira, F Villacampa, JM Paramio, M Martínez-Fernández
Publication Date: 2019-07-17

Variant appearance in text: N/A
PMID: 31316092
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Association of the TP53 rs1042522 C>G polymorphism and hepatoblastoma risk in Chinese children.

Journal Of Cancer
T Yang, Y Wen, J Li, J Yang, T Tan, J Pan, C Hu, J Zhang, Y Xin, S Li, H Xia, J He, Y Zou
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31293648
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The 45th Annual Meeting of the European Society for Blood and Marrow Transplantation: Physicians - Poster Session.

Bone Marrow Transplantation
.
Publication Date: 2019-07

Variant appearance in text: TP53: P72R
PMID: 31270396
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Establishment and characterization of patient-derived organoids from a young patient with cervical clear cell carcinoma.

Cancer Science
Y Maru, N Tanaka, K Ebisawa, A Odaka, T Sugiyama, M Itami, Y Hippo
Publication Date: 2019-09

Variant appearance in text: N/A
PMID: 31265190
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Phase 1b study of the MDM2 inhibitor AMG 232 with or without trametinib in relapsed/refractory acute myeloid leukemia.

Blood Advances
HP Erba, PS Becker, PJ Shami, MR Grunwald, DL Flesher, M Zhu, E Rasmussen, HA Henary, AA Anderson, ES Wang
Publication Date: 2019-07-09

Variant appearance in text: TP53: Pro72Arg
PMID: 31253596
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A case of biliary adenofibroma of the liver with malignant transformation: a morphomolecular case report and review of the literature.

Surgical Case Reports
AK Sturm, T Welsch, C Meissner, DE Aust, G Baretton
Publication Date: 2019-06-24

Variant appearance in text: TP53: 215C>G
PMID: 31236706
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Association between TP53 gene codon72 polymorphism and prostate cancer risk: A systematic review and meta-analysis.

Medicine
PZ Han, DH Cao, XL Zhang, ZJ Ren, Q Wei
Publication Date: 2019-06

Variant appearance in text: N/A
PMID: 31232967
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Molecular characterization of carcinosarcomas arising in the uterus and ovaries.

Oncotarget
M Brunetti, A Agostini, J Staurseth, B Davidson, S Heim, F Micci
Publication Date: 2019-06-04

Variant appearance in text: TP53: 215C>G
PMID: 31217897
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Laying the foundation for genomically-based risk assessment in chronic myeloid leukemia.

Leukemia
S Branford, DDH Kim, JF Apperley, CA Eide, S Mustjoki, ST Ong, G Nteliopoulos, T Ernst, C Chuah, C Gambacorti-Passerini, MJ Mauro, BJ Druker, DW Kim, FX Mahon, J Cortes, JP Radich, A Hochhaus, TP Hughes,
Publication Date: 2019-08

Variant appearance in text: TP53: 215C>G; Pro72Arg
PMID: 31209280
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Five P53 SNPs Involved in Low Rectal Cancer Risk and Prognosis in a Chinese Population.

Journal Of Cancer
G Zhang, Q Xu, J Liu, Z Lv, Y Lu, H Yang, L Sun, C Xing, Y Yuan
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31205533
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Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis.

Cell Stem Cell
M Huang, J Tailor, Q Zhen, AH Gillmor, ML Miller, H Weishaupt, J Chen, T Zheng, EK Nash, LK McHenry, Z An, F Ye, Y Takashima, J Clarke, H Ayetey, FMG Cavalli, B Luu, BS Moriarity, S Ilkhanizadeh, L Chavez, C Yu, KM Kurian, T Magnaldo, N Sevenet, P Koch, SM Pollard, P Dirks, MP Snyder, DA Largaespada, YJ Cho, JJ Phillips, FJ Swartling, AS Morrissy, M Kool, SM Pfister, MD Taylor, A Smith, WA Weiss
Publication Date: 2019-09-05

Variant appearance in text: TP53: P72R; rs1042522
PMID: 31204176
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Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy.

Cancer Cell
Y Fang, DJ McGrail, C Sun, M Labrie, X Chen, D Zhang, Z Ju, CP Vellano, Y Lu, Y Li, KJ Jeong, Z Ding, J Liang, SW Wang, H Dai, S Lee, N Sahni, I Mercado-Uribe, TB Kim, K Chen, SY Lin, G Peng, SN Westin, J Liu, MJ O'Connor, TA Yap, GB Mills
Publication Date: 2019-06-10

Variant appearance in text: TP53: P72R
PMID: 31185210
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Common genetic variants in the TP53 pathway and their impact on cancer.

Journal Of Molecular Cell Biology
T Barnoud, JLD Parris, ME Murphy
Publication Date: 2019-07-19

Variant appearance in text: p53: Pro72Arg; rs1042522
PMID: 31152665
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Establishment of Highly Transplantable Cholangiocarcinoma Cell Lines from a Patient-Derived Xenograft Mouse Model.

Cells
K Vaeteewoottacharn, C Pairojkul, R Kariya, K Muisuk, K Imtawil, Y Chamgramol, V Bhudhisawasdi, N Khuntikeo, A Pugkhem, OT Saeseow, A Silsirivanit, C Wongkham, S Wongkham, S Okada
Publication Date: 2019-05-23

Variant appearance in text: TP53: P72R
PMID: 31126020
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Esophageal cancer genetics in South Africa.

Clinical And Experimental Gastroenterology
M Alaouna, R Hull, C Penny, Z Dlamini
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31114287
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p53 polymorphism and association of human papillomavirus in oral submucous fibrosis and oral squamous cell carcinoma: A case-control study.

Journal Of Oral And Maxillofacial Pathology : Jomfp
K Hallikeri, K Burde, V Anehosur, BB Kulkarni, SV Hiremath
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31110424
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Polymorphisms of ADME-related genes and their implications for drug safety and efficacy in Amazonian Amerindians.

Scientific Reports
JCG Rodrigues, MR Fernandes, JF Guerreiro, ALDC da Silva, Â Ribeiro-Dos-Santos, S Santos, NPCD Santos
Publication Date: 2019-05-10

Variant appearance in text: N/A
PMID: 31076604
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Impact of MDM2, TP53 and P14ARF Polymorphisms on Endometrial Cancer Risk and Onset.

In Vivo (Athens, Greece)
W Wujcicka, A Zając, G Stachowiak
Publication Date: 2019

Variant appearance in text: N/A
PMID: 31028217
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miR-125b Upregulates miR-34a and Sequentially Activates Stress Adaption and Cell Death Mechanisms in Multiple Myeloma.

Molecular Therapy. Nucleic Acids
G Misso, MR Zarone, A Lombardi, A Grimaldi, AM Cossu, C Ferri, M Russo, DC Vuoso, A Luce, H Kawasaki, MT Di Martino, A Virgilio, A Festa, A Galeone, G De Rosa, C Irace, M Donadelli, A Necas, E Amler, P Tagliaferri, P Tassone, M Caraglia
Publication Date: 2019-06-07

Variant appearance in text: TP53: P72R
PMID: 31009917
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Defining the genetic profile of endometriosis.

Experimental And Therapeutic Medicine
L Vassilopoulou, M Matalliotakis, MI Zervou, C Matalliotaki, K Krithinakis, I Matalliotakis, DA Spandidos, GN Goulielmos
Publication Date: 2019-05

Variant appearance in text: N/A
PMID: 30988702
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New Chondrosarcoma Cell Lines with Preserved Stem Cell Properties to Study the Genomic Drift During In Vitro/In Vivo Growth.

Journal Of Clinical Medicine
V Rey, ST Menendez, O Estupiñan, A Rodriguez, L Santos, J Tornin, L Martinez-Cruzado, D Castillo, GR Ordoñez, S Costilla, C Alvarez-Fernandez, A Astudillo, A Braña, R Rodriguez
Publication Date: 2019-04-04

Variant appearance in text: TP53: P72R
PMID: 30987403
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Mechanistic insights into environmental and genetic risk factors for systemic lupus erythematosus.

American Journal Of Translational Research
Q Pan, J Chen, L Guo, X Lu, S Liao, C Zhao, S Wang, H Liu
Publication Date: 2019

Variant appearance in text: N/A
PMID: 30972159
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Genetic Susceptibility in Head and Neck Squamous Cell Carcinoma in a Spanish Population.

Cancers
J Fernández-Mateos, R Seijas-Tamayo, JC Adansa Klain, M Pastor Borgoñón, E Pérez-Ruiz, R Mesía, E Del Barco, C Salvador Coloma, A Rueda Dominguez, J Caballero Daroqui, E Fernández Ruiz, A Ocana, R González-Sarmiento, JJ Cruz-Hernández
Publication Date: 2019-04-07

Variant appearance in text: TP53: 215C>G; rs1042522
PMID: 30959967
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Alternative transcript annotations:

Transcript cDNA Protein Consequence Exon Intron
ENST00000269305.4 c.215C>G p.Pro72Arg missense_variant 4/11 -
ENST00000359597.4 c.215C>G p.Pro72Arg missense_variant 3/9 -
ENST00000413465.2 c.215C>G p.Pro72Arg missense_variant 3/7 -
ENST00000420246.2 c.215C>G p.Pro72Arg missense_variant 4/12 -
ENST00000445888.2 c.215C>G p.Pro72Arg missense_variant 4/11 -
ENST00000455263.2 c.215C>G p.Pro72Arg missense_variant 4/12 -
ENST00000503591.1 c.215C>G p.Pro72Arg missense_variant 5/6 -
ENST00000505014.1 n.471C>G - non_coding_transcript_exon_variant 3/5 -
ENST00000508793.1 c.215C>G p.Pro72Arg missense_variant 4/5 -
ENST00000509690.1 c.-21-918C>G - intron_variant - 1/5
ENST00000514944.1 c.96+228C>G - intron_variant - 3/5
ENST00000604348.1 c.215C>G p.Pro72Arg missense_variant 4/5 -
NM_000546.5 c.215C>G p.Pro72Arg missense_variant 4/11 -
NM_001126112.2 c.215C>G p.Pro72Arg missense_variant 4/11 -
NM_001126113.2 c.215C>G p.Pro72Arg missense_variant 4/12 -
NM_001126114.2 c.215C>G p.Pro72Arg missense_variant 4/12 -
NM_001126118.1 c.98C>G p.Pro33Arg missense_variant 3/10 -
NM_001276695.2 c.98C>G p.Pro33Arg missense_variant 4/12 -
NM_001276696.2 c.98C>G p.Pro33Arg missense_variant 4/12 -
NM_001276760.2 c.98C>G p.Pro33Arg missense_variant 4/11 -
NM_001276761.2 c.98C>G p.Pro33Arg missense_variant 4/11 -