Publications:

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: TP53: A69D

PubMed Link: 36396655

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• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

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Reduction of H3K27cr Modification During DNA Damage in Colon Cancer.

Frontiers In Oncology

Liao, Meijian M; Chu, Weiwei W; Sun, Xiaolin X; Zheng, Wendan W; Gao, Shoucui S; Li, Danhua D; Pei, Dongsheng D

Publication Date: 2022

Variant appearance in text: p53: A69D

PubMed Link: 35936700

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• Table_10.xlsx, sheet 1

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Cyclophilin B overexpression predicts a poor prognosis and activates metastatic pathways in colon cancer.

Translational Cancer Research

Zhang, Xiaojing X; Tan, Jinjing J; Yang, Lei L; An, Guangyu G

Publication Date: 2020-05

Variant appearance in text: p53: A69D

PubMed Link: 35117721

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• tcr-09-05-3573.pdf

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Fibroblast growth factor (FGF), FGF receptor (FGFR), and cyclin D1 (CCND1) DNA methylation in head and neck squamous cell carcinomas is associated with transcriptional activity, gene amplification, human papillomavirus (HPV) status, and sensitivity to tyrosine kinase inhibitors.

Clinical Epigenetics

Bao, Yilin Y; Gabrielpillai, Jennis J; Dietrich, Jörn J; Zarbl, Romina R; Strieth, Sebastian S; Schröck, Friederike F; Dietrich, Dimo D

Publication Date: 2021-12-21

Variant appearance in text: TP53: A69D

PubMed Link: 34933671

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• Main text

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Do age, fitness and concomitant medications influence management and outcomes of CLL patients treated with ibrutinib?

Blood Advances

Tedeschi, Alessandra A; Frustaci, Anna Maria AM; Mauro, Francesca Romana FR; Chiarenza, Annalisa A; Coscia, Marta M; Ciolli, Stefania S; Reda, Gianluigi G; Laurenti, Luca L; Varettoni, Marzia M; Murru, Roberta R; Baratè, Claudia C; Sportoletti, Paolo P; Greco, Antonino A; Borella, Chiara C; Rossi, Valentina V; Deodato, Marina M; Biagi, Annalisa A; Zamprogna, Giulia G; Curto Pelle, Angelo A; Lapietra, Gianfranco G; Vitale, Candida C; Morelli, Francesca F; Cassin, Ramona R; Fresa, Alberto A; Cavalloni, Chiara C; Postorino, Massimiliano M; Ielo, Claudia C; Cairoli, Roberto R; Di Raimondo, Francesco F; Montillo, Marco M; Del Poeta, Giovanni G

Publication Date: 2021-09-15

Variant appearance in text: TP53: A69D

PubMed Link: 34525181

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• Main text

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Methylglyoxal induces p53 activation and inhibits mTORC1 in human umbilical vein endothelial cells.

Scientific Reports

Zhang, Xinmiao X; Rodriguez-Niño, Angelica A; Pastene, Diego O DO; Pallavi, Prama P; van den Born, Jacob J; Bakker, Stephan J L SJL; Krämer, Bernhard K BK; Yard, Benito A BA

Publication Date: 2021-04-13

Variant appearance in text: p53: A69D

PubMed Link: 33850227

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Matrix metalloproteinase-10 protects against acute kidney injury by augmenting epidermal growth factor receptor signaling.

Cell Death & Disease

Hu, Chengxiao C; Zuo, Yangyang Y; Ren, Qian Q; Sun, Xiaoli X; Zhou, Shan S; Liao, Jinlin J; Hong, Xue X; Miao, Jinhua J; Zhou, Lili L; Liu, Youhua Y

Publication Date: 2021-01-12

Variant appearance in text: p53: A69D

PubMed Link: 33436543

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Comprehensive analysis of partial epithelial mesenchymal transition-related genes in hepatocellular carcinoma.

Journal Of Cellular And Molecular Medicine

Lei, Yu Y; Yan, Wei W; Lin, Zhuoying Z; Liu, Jingmei J; Tian, Dean D; Han, Ping P

Publication Date: 2021-01

Variant appearance in text: p53: A69D

PubMed Link: 33215860

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Integrated molecular characterization reveals potential therapeutic strategies for pulmonary sarcomatoid carcinoma.

Nature Communications

Yang, Zhenlin Z; Xu, Jiachen J; Li, Lin L; Li, Renda R; Wang, Yalong Y; Tian, Yanhua Y; Guo, Wei W; Wang, Zhijie Z; Tan, Fengwei F; Ying, Jianming J; Jiao, Yuchen Y; Gao, Shugeng S; Wang, Jie J; Gao, Yibo Y; He, Jie J

Publication Date: 2020-09-28

Variant appearance in text: TP53: A69D

PubMed Link: 32985499

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20(S)-Protopanaxatriol promotes the binding of P53 and DNA to regulate the antitumor network via multiomic analysis.

Acta Pharmaceutica Sinica. B

Wang, Zhihua Z; Wu, Wenbo W; Guan, Xiangchen X; Guo, Shuang S; Li, Chaowen C; Niu, Ruixue R; Gao, Jie J; Jiang, Min M; Bai, Liping L; Leung, Elaine Laihan EL; Hou, Yuanyuan Y; Jiang, Zhihong Z; Bai, Gang G

Publication Date: 2020-06

Variant appearance in text: TP53: A69D

PubMed Link: 32642409

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Construction of an integrated prognostic classifier model for predicting the efficacy of immune checkpoint inhibitor therapy in non-small cell lung cancer.

Cancer Communications (London, England)

Lin, Zhihuan Z; Zhang, Yaxiong Y; Zhang, Li L

Publication Date: 2020-08

Variant appearance in text: TP53: A69D

PubMed Link: 32639662

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Examining multiple cellular pathways at once using multiplex hextuple luciferase assaying.

Nature Communications

Sarrion-Perdigones, Alejandro A; Chang, Lyra L; Gonzalez, Yezabel Y; Gallego-Flores, Tatiana T; Young, Damian W DW; Venken, Koen J T KJT

Publication Date: 2019-12-13

Variant appearance in text: p53: A69D

PubMed Link: 31836712

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Identification of predictors of drug sensitivity using patient-derived models of esophageal squamous cell carcinoma.

Nature Communications

Su, Dan D; Zhang, Dadong D; Jin, Jiaoyue J; Ying, Lisha L; Han, Miao M; Chen, Kaiyan K; Li, Bin B; Wu, Junzhou J; Xie, Zhenghua Z; Zhang, Fanrong F; Lin, Yihui Y; Cheng, Guoping G; Li, Jing-Yu JY; Huang, Minran M; Wang, Jinchao J; Wang, Kailai K; Zhang, Jianjun J; Li, Fugen F; Xiong, Lei L; Futreal, Andrew A; Mao, Weimin W

Publication Date: 2019-11-07

Variant appearance in text: TP53: 206C>A

PubMed Link: 31700061

Variant Present in the following documents:

• 41467_2019_12846_MOESM6_ESM.xlsx, sheet 1

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Massive computational identification of somatic variants in exonic splicing enhancers using The Cancer Genome Atlas.

Cancer Medicine

Tanimoto, Kousuke K; Muramatsu, Tomoki T; Inazawa, Johji J

Publication Date: 2019-12

Variant appearance in text: TP53: A69D

PubMed Link: 31631560

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• CAM4-8-7372-s007.xlsx, sheet 1

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Long-term effects of maternal choline supplementation on CA1 pyramidal neuron gene expression in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.

Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology

Alldred, Melissa J MJ; Chao, Helen M HM; Lee, Sang Han SH; Beilin, Judah J; Powers, Brian E BE; Petkova, Eva E; Strupp, Barbara J BJ; Ginsberg, Stephen D SD

Publication Date: 2019-09

Variant appearance in text: TP53: A69D

PubMed Link: 31180719

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: TP53: A69D

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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Parsimonious Gene Correlation Network Analysis (PGCNA): a tool to define modular gene co-expression for refined molecular stratification in cancer.

Npj Systems Biology And Applications

Care, Matthew A MA; Westhead, David R DR; Tooze, Reuben M RM

Publication Date: 2019

Variant appearance in text: TP53: A69D

PubMed Link: 30993001

Variant Present in the following documents:

• 41540_2019_90_MOESM2_ESM.pdf

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The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma.

Bmc Medical Genetics

Fedorova, Maria S MS; Krasnov, George S GS; Lukyanova, Elena N EN; Zaretsky, Andrew R AR; Dmitriev, Alexey A AA; Melnikova, Nataliya V NV; Moskalev, Alexey A AA; Kharitonov, Sergey L SL; Pudova, Elena A EA; Guvatova, Zulfiya G ZG; Kobelyatskaya, Anastasiya A AA; Ishina, Irina A IA; Slavnova, Elena N EN; Lipatova, Anastasia V AV; Chernichenko, Maria A MA; Sidorov, Dmitry V DV; Popov, Anatoly Y AY; Kiseleva, Marina V MV; Kaprin, Andrey D AD; Snezhkina, Anastasiya V AV; Kudryavtseva, Anna V AV

Publication Date: 2019-04-09

Variant appearance in text: TP53: A69D

PubMed Link: 30967137

Variant Present in the following documents:

• 12881_2019_771_MOESM2_ESM.xlsx, sheet 2

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Whole-exon sequencing of human myeloma cell lines shows mutations related to myeloma patients at relapse with major hits in the DNA regulation and repair pathways.

Journal Of Hematology & Oncology

Tessoulin, Benoît B; Moreau-Aubry, Agnès A; Descamps, Géraldine G; Gomez-Bougie, Patricia P; Maïga, Sophie S; Gaignard, Alban A; Chiron, David D; Ménoret, Emmanuelle E; Le Gouill, Steven S; Moreau, Philippe P; Amiot, Martine M; Pellat-Deceunynck, Catherine C

Publication Date: 2018-12-13

Variant appearance in text: TP53: Ala69Asp

PubMed Link: 30545397

Variant Present in the following documents:

• 13045_2018_679_MOESM2_ESM.xlsx, sheet 1

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Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.

The Journal Of Pathology

Temko, Daniel D; Van Gool, Inge C IC; Rayner, Emily E; Glaire, Mark M; Makino, Seiko S; Brown, Matthew M; Chegwidden, Laura L; Palles, Claire C; Depreeuw, Jeroen J; Beggs, Andrew A; Stathopoulou, Chaido C; Mason, John J; Baker, Ann-Marie AM; Williams, Marc M; Cerundolo, Vincenzo V; Rei, Margarida M; Taylor, Jenny C JC; Schuh, Anna A; Ahmed, Ahmed A; Amant, Frédéric F; Lambrechts, Diether D; Smit, Vincent Thbm VT; Bosse, Tjalling T; Graham, Trevor A TA; Church, David N DN; Tomlinson, Ian I

Publication Date: 2018-07

Variant appearance in text: TP53: A69D

PubMed Link: 29604063

Variant Present in the following documents:

• PATH-245-283-s022.xlsx, sheet 1

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HIT'nDRIVE: patient-specific multidriver gene prioritization for precision oncology.

Genome Research

Shrestha, Raunak R; Hodzic, Ermin E; Sauerwald, Thomas T; Dao, Phuong P; Wang, Kendric K; Yeung, Jake J; Anderson, Shawn S; Vandin, Fabio F; Haffari, Gholamreza G; Collins, Colin C CC; Sahinalp, S Cenk SC

Publication Date: 2017-09

Variant appearance in text: TP53: A69D

PubMed Link: 28768687

Variant Present in the following documents:

• supp_gr.221218.117_Supplemental_Table_S21.xlsx, sheet 1

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: A69D

PubMed Link: 27527004

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• srep31321-s5.xls, sheet 1

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: TP53: A69D

PubMed Link: 26206375

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• 12859_2015_673_MOESM1_ESM.xls, sheet 1

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: A69D

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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Network-based identification of key proteins involved in apoptosis and cell cycle regulation.

Cell Proliferation

Wu, L L; Zhou, N N; Sun, R R; Chen, X D XD; Feng, S C SC; Zhang, B B; Bao, J K JK

Publication Date: 2014-08

Variant appearance in text: p53: A69D

PubMed Link: 24889965

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