TP53 c.163A>G ;(p.T55A)

Variant ID: 17-7579524-T-C

NM_000546.5(TP53):c.163A>G;(p.T55A)

This variant was identified in 12 publications

View GRCh38 version.




Publications:


Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: TP53: 163A>G
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



Analysis of conventional and alternative CRISPR/Cas9 genome editing to enhance a single-base pair knock-in mutation.

Bmc Biotechnology
Edmondson, Carina C; Zhou, Qi Q; Liu, Xuan X
Publication Date: 2021-07-27

Variant appearance in text: p53: T55A
PubMed Link: 34315458
Variant Present in the following documents:
  • Main text
  • 12896_2021_Article_707.pdf
View BVdb publication page



Use of Gene Therapy in Retinal Ganglion Cell Neuroprotection: Current Concepts and Future Directions.

Biomolecules
Rhee, Jess J; Shih, Kendrick Co KC
Publication Date: 2021-04-15

Variant appearance in text: p53: T55A
PubMed Link: 33920974
Variant Present in the following documents:
  • Main text
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A phosphorylation-dependent switch in the disordered p53 transactivation domain regulates DNA binding.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Sun, Xun X; Dyson, H Jane HJ; Wright, Peter E PE
Publication Date: 2021-01-05

Variant appearance in text: p53: T55A
PubMed Link: 33443163
Variant Present in the following documents:
  • Main text
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Thr55 phosphorylation of p21 by MPK38/MELK ameliorates defects in glucose, lipid, and energy metabolism in diet-induced obese mice.

Cell Death & Disease
Seong, Hyun-A HA; Ha, Hyunjung H
Publication Date: 2019-05-16

Variant appearance in text: p53: T55A
PubMed Link: 31097688
Variant Present in the following documents:
  • Main text
  • 41419_2019_Article_1616.pdf
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High glucose-induced p53 phosphorylation contributes to impairment of endothelial antioxidant system.

Biochimica Et Biophysica Acta. Molecular Basis Of Disease
Wu, Yong Y; Lee, Sangkyu S; Bobadilla, Selene S; Duan, Sheng Zhong SZ; Liu, Xuan X
Publication Date: 2017-09

Variant appearance in text: p53: T55A
PubMed Link: 28673515
Variant Present in the following documents:
  • Main text
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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: T55A
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
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p53 regulation upon genotoxic stress: intricacies and complexities.

Molecular & Cellular Oncology
Kumari, Rajni R; Kohli, Saishruti S; Das, Sanjeev S
Publication Date: 2014

Variant appearance in text: p53: T55A
PubMed Link: 27308356
Variant Present in the following documents:
  • Main text
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Characterization of the p300 Taz2-p53 TAD2 complex and comparison with the p300 Taz2-p53 TAD1 complex.

Biochemistry
Miller Jenkins, Lisa M LM; Feng, Hanqiao H; Durell, Stewart R SR; Tagad, Harichandra D HD; Mazur, Sharlyn J SJ; Tropea, Joseph E JE; Bai, Yawen Y; Appella, Ettore E
Publication Date: 2015-03-24

Variant appearance in text: p53: T55A
PubMed Link: 25753752
Variant Present in the following documents:
  • Main text
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Phosphorylation of p53 by TAF1 inactivates p53-dependent transcription in the DNA damage response.

Molecular Cell
Wu, Yong Y; Lin, Joy C JC; Piluso, Landon G LG; Dhahbi, Joseph M JM; Bobadilla, Selene S; Spindler, Stephen R SR; Liu, Xuan X
Publication Date: 2014-01-09

Variant appearance in text: p53: T55A
PubMed Link: 24289924
Variant Present in the following documents:
  • Main text
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G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis.

The Journal Of Biological Chemistry
Chen, Xiaoqing X; Zhu, Huiling H; Yuan, Man M; Fu, Jie J; Zhou, Yuqing Y; Ma, Lan L
Publication Date: 2010-04-23

Variant appearance in text: p53: T55A
PubMed Link: 20124405
Variant Present in the following documents:
  • Main text
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Inhibition of Thr-55 phosphorylation restores p53 nuclear localization and sensitizes cancer cells to DNA damage.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Cai, Xin X; Liu, Xuan X
Publication Date: 2008-11-04

Variant appearance in text: p53: T55A
PubMed Link: 18952844
Variant Present in the following documents:
  • Main text
View BVdb publication page