TP53 c.161T>C ;(p.F54S)

Variant ID: 17-7579526-A-G

NM_000546.5(TP53):c.161T>C;(p.F54S)

This variant was identified in 19 publications

View GRCh38 version.




Publications:


The Competition of Yin and Yang: Exploring the Role of Wild-Type and Mutant p53 in Tumor Progression.

Biomedicines
Cai, Bi-He BH; Sung, Yu-Te YT; Chen, Chia-Chi CC; Shaw, Jei-Fu JF; Hsin, I-Lun IL
Publication Date: 2023-04-17

Variant appearance in text: p53: F54S
PubMed Link: 37189810
Variant Present in the following documents:
  • Main text
  • biomedicines-11-01192.pdf
View BVdb publication page



Ferroptosis in Carcinoma: Regulatory Mechanisms and New Method for Cancer Therapy.

Oncotargets And Therapy
Shi, Zhi-Zhou ZZ; Fan, Ze-Wen ZW; Chen, Yun-Xia YX; Xie, Xiu-Feng XF; Jiang, Wen W; Wang, Wen-Jun WJ; Qiu, Yun-Tan YT; Bai, Jie J
Publication Date: 2019

Variant appearance in text: p53: F54S
PubMed Link: 31908494
Variant Present in the following documents:
  • Main text
  • ott-12-11291.pdf
View BVdb publication page



Gain-of-function mutant p53: history and speculation.

Journal Of Molecular Cell Biology
Bargonetti, Jill J; Prives, Carol C
Publication Date: 2019-07-19

Variant appearance in text: p53: F54S
PubMed Link: 31283823
Variant Present in the following documents:
  • Main text
  • mjz067.pdf
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: TP53: F54S
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



HPV16 E7 Genetic Conservation Is Critical to Carcinogenesis.

Cell
Mirabello, Lisa L; Yeager, Meredith M; Yu, Kai K; Clifford, Gary M GM; Xiao, Yanzi Y; Zhu, Bin B; Cullen, Michael M; Boland, Joseph F JF; Wentzensen, Nicolas N; Nelson, Chase W CW; Raine-Bennett, Tina T; Chen, Zigui Z; Bass, Sara S; Song, Lei L; Yang, Qi Q; Steinberg, Mia M; Burdett, Laurie L; Dean, Michael M; Roberson, David D; Mitchell, Jason J; Lorey, Thomas T; Franceschi, Silvia S; Castle, Philip E PE; Walker, Joan J; Zuna, Rosemary R; Kreimer, Aimée R AR; Beachler, Daniel C DC; Hildesheim, Allan A; Gonzalez, Paula P; Porras, Carolina C; Burk, Robert D RD; Schiffman, Mark M
Publication Date: 2017-09-07

Variant appearance in text: p53: F54S
PubMed Link: 28886384
Variant Present in the following documents:
  • Main text
View BVdb publication page



An extensive molecular cytogenetic characterization in high-risk chronic lymphocytic leukemia identifies karyotype aberrations and TP53 disruption as predictors of outcome and chemorefractoriness.

Oncotarget
Rigolin, Gian Matteo GM; Formigaro, Luca L; Cavallari, Maurizio M; Quaglia, Francesca Maria FM; Lista, Enrico E; Urso, Antonio A; Guardalben, Emanuele E; Martinelli, Sara S; Saccenti, Elena E; Bassi, Cristian C; Lupini, Laura L; Bardi, Maria Antonella MA; Volta, Eleonora E; Tammiso, Elisa E; Melandri, Aurora A; Negrini, Massimo M; Cavazzini, Francesco F; Cuneo, Antonio A
Publication Date: 2017-04-25

Variant appearance in text: TP53: F54S
PubMed Link: 28427204
Variant Present in the following documents:
  • oncotarget-08-28008-s003.xlsx, sheet 1
View BVdb publication page



Mutant p53 establishes targetable tumor dependency by promoting unscheduled replication.

The Journal Of Clinical Investigation
Singh, Shilpa S; Vaughan, Catherine A CA; Frum, Rebecca A RA; Grossman, Steven R SR; Deb, Sumitra S; Palit Deb, Swati S
Publication Date: 2017-05-01

Variant appearance in text: p53: F54S
PubMed Link: 28394262
Variant Present in the following documents:
  • Main text
View BVdb publication page



The Transactivation Domains of the p53 Protein.

Cold Spring Harbor Perspectives In Medicine
Raj, Nitin N; Attardi, Laura D LD
Publication Date: 2017-01-03

Variant appearance in text: p53: F54S
PubMed Link: 27864306
Variant Present in the following documents:
  • Main text
View BVdb publication page



Extensive next-generation sequencing analysis in chronic lymphocytic leukemia at diagnosis: clinical and biological correlations.

Journal Of Hematology & Oncology
Rigolin, Gian Matteo GM; Saccenti, Elena E; Bassi, Cristian C; Lupini, Laura L; Quaglia, Francesca Maria FM; Cavallari, Maurizio M; Martinelli, Sara S; Formigaro, Luca L; Lista, Enrico E; Bardi, Maria Antonella MA; Volta, Eleonora E; Tammiso, Elisa E; Melandri, Aurora A; Urso, Antonio A; Cavazzini, Francesco F; Negrini, Massimo M; Cuneo, Antonio A
Publication Date: 2016-09-15

Variant appearance in text: TP53: F54S
PubMed Link: 27633522
Variant Present in the following documents:
  • 13045_2016_320_MOESM1_ESM.xlsx, sheet 1
View BVdb publication page



iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: F54S
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
View BVdb publication page



Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses.

Cell Cycle (Georgetown, Tex.)
Jiang, Le L; Hickman, Justin H JH; Wang, Shang-Jui SJ; Gu, Wei W
Publication Date: 2015

Variant appearance in text: p53: F54S
PubMed Link: 26218928
Variant Present in the following documents:
  • Main text
View BVdb publication page



Characterization of the p300 Taz2-p53 TAD2 complex and comparison with the p300 Taz2-p53 TAD1 complex.

Biochemistry
Miller Jenkins, Lisa M LM; Feng, Hanqiao H; Durell, Stewart R SR; Tagad, Harichandra D HD; Mazur, Sharlyn J SJ; Tropea, Joseph E JE; Bai, Yawen Y; Appella, Ettore E
Publication Date: 2015-03-24

Variant appearance in text: p53: F54S
PubMed Link: 25753752
Variant Present in the following documents:
  • Main text
View BVdb publication page



p53 suppresses muscle differentiation at the myogenin step in response to genotoxic stress.

Cell Death And Differentiation
Yang, Z J P ZJ; Broz, D Kenzelmann DK; Noderer, W L WL; Ferreira, J P JP; Overton, K W KW; Spencer, S L SL; Meyer, T T; Tapscott, S J SJ; Attardi, L D LD; Wang, C L CL
Publication Date: 2015-04

Variant appearance in text: p53: F54S
PubMed Link: 25501595
Variant Present in the following documents:
  • Main text
View BVdb publication page



Guilty as CHARGED: p53's expanding role in disease.

Cell Cycle (Georgetown, Tex.)
Van Nostrand, Jeanine L JL; Attardi, Laura D LD
Publication Date: 2014

Variant appearance in text: p53: F54S
PubMed Link: 25483057
Variant Present in the following documents:
  • Main text
View BVdb publication page



Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: TP53: F54S
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



Unravelling mechanisms of p53-mediated tumour suppression.

Nature Reviews. Cancer
Bieging, Kathryn T KT; Mello, Stephano Spano SS; Attardi, Laura D LD
Publication Date: 2014-05

Variant appearance in text: p53: F54S
PubMed Link: 24739573
Variant Present in the following documents:
  • Main text
View BVdb publication page



Illuminating p53 function in cancer with genetically engineered mouse models.

Seminars In Cell & Developmental Biology
Garcia, Patty B PB; Attardi, Laura D LD
Publication Date: 2014-03

Variant appearance in text: p53: F54S
PubMed Link: 24394915
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway.

Cell
Freed-Pastor, William A WA; Mizuno, Hideaki H; Zhao, Xi X; Langerød, Anita A; Moon, Sung-Hwan SH; Rodriguez-Barrueco, Ruth R; Barsotti, Anthony A; Chicas, Agustin A; Li, Wencheng W; Polotskaia, Alla A; Bissell, Mina J MJ; Osborne, Timothy F TF; Tian, Bin B; Lowe, Scott W SW; Silva, Jose M JM; Børresen-Dale, Anne-Lise AL; Levine, Arnold J AJ; Bargonetti, Jill J; Prives, Carol C
Publication Date: 2012-01-20

Variant appearance in text: p53: F54S
PubMed Link: 22265415
Variant Present in the following documents:
  • Main text
View BVdb publication page



Multivalent binding of p53 to the STAGA complex mediates coactivator recruitment after UV damage.

Molecular And Cellular Biology
Gamper, Armin M AM; Roeder, Robert G RG
Publication Date: 2008-04

Variant appearance in text: p53: F54S
PubMed Link: 18250150
Variant Present in the following documents:
  • Main text
View BVdb publication page