Publications:

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Subclonal reconstruction of tumors by using machine learning and population genetics.

Nature Genetics

Caravagna, Giulio G; Heide, Timon T; Williams, Marc J MJ; Zapata, Luis L; Nichol, Daniel D; Chkhaidze, Ketevan K; Cross, William W; Cresswell, George D GD; Werner, Benjamin B; Acar, Ahmet A; Chesler, Louis L; Barnes, Chris P CP; Sanguinetti, Guido G; Graham, Trevor A TA; Sottoriva, Andrea A

Publication Date: 2020-09

Variant appearance in text: TP53: f54a

PubMed Link: 32879509

Variant Present in the following documents:

• EMS118434-supplement-Supplementary_Notes_and_Figures.pdf

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Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis.

Nature Communications

Emond, Stephane S; Petek, Maya M; Kay, Emily J EJ; Heames, Brennen B; Devenish, Sean R A SRA; Tokuriki, Nobuhiko N; Hollfelder, Florian F

Publication Date: 2020-07-10

Variant appearance in text: p53: F54a

PubMed Link: 32651386

Variant Present in the following documents:

• 41467_2020_17061_MOESM2_ESM.pdf

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Post-Transcriptional Dysregulation of microRNA and Alternative Polyadenylation in Colorectal Cancer.

Frontiers In Genetics

Mao, Zhanrui Z; Zhao, Hui H; Qin, Yulan Y; Wei, Jianming J; Sun, Jielin J; Zhang, Weiwei W; Kang, Yani Y

Publication Date: 2020

Variant appearance in text: TP53: F54A

PubMed Link: 32153636

Variant Present in the following documents:

• Main text

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Structural Basis for the Interaction between p53 Transactivation Domain and the Mediator Subunit MED25.

Molecules (Basel, Switzerland)

Lee, Min-Sung MS; Lim, Kyungeun K; Lee, Mi-Kyung MK; Chi, Seung-Wook SW

Publication Date: 2018-10-22

Variant appearance in text: p53: F54A

PubMed Link: 30360415

Variant Present in the following documents:

• Main text
• molecules-23-02726.pdf

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The complex binding mode of the peptide hormone H2 relaxin to its receptor RXFP1.

Nature Communications

Sethi, Ashish A; Bruell, Shoni S; Patil, Nitin N; Hossain, Mohammed Akhter MA; Scott, Daniel J DJ; Petrie, Emma J EJ; Bathgate, Ross A D RAD; Gooley, Paul R PR

Publication Date: 2016-04-18

Variant appearance in text: p53: F54A

PubMed Link: 27088579

Variant Present in the following documents:

• ncomms11344.pdf

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Dual-site interactions of p53 protein transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways.

The Journal Of Biological Chemistry

Ha, Ji-Hyang JH; Shin, Jae-Sun JS; Yoon, Mi-Kyung MK; Lee, Min-Sung MS; He, Fahu F; Bae, Kwang-Hee KH; Yoon, Ho Sup HS; Lee, Chong-Kil CK; Park, Sung Goo SG; Muto, Yutaka Y; Chi, Seung-Wook SW

Publication Date: 2013-03-08

Variant appearance in text: p53: F54A

PubMed Link: 23316052

Variant Present in the following documents:

• Main text

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Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Rajagopalan, Sridharan S; Andreeva, Antonina A; Rutherford, Trevor J TJ; Fersht, Alan R AR

Publication Date: 2010-05-11

Variant appearance in text: p53: F54A

PubMed Link: 20421506

Variant Present in the following documents:

• Main text

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Interaction between the transactivation domain of p53 and PC4 exemplifies acidic activation domains as single-stranded DNA mimics.

The Journal Of Biological Chemistry

Rajagopalan, Sridharan S; Andreeva, Antonina A; Teufel, Daniel P DP; Freund, Stefan M SM; Fersht, Alan R AR

Publication Date: 2009-08-07

Variant appearance in text: p53: F54A

PubMed Link: 19525231

Variant Present in the following documents:

• Main text
• zbc21728.pdf

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