Publications:

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Base editing sensor libraries for high-throughput engineering and functional analysis of cancer-associated single nucleotide variants.

Nature Biotechnology

Sánchez-Rivera, Francisco J FJ; Diaz, Bianca J BJ; Kastenhuber, Edward R ER; Schmidt, Henri H; Katti, Alyna A; Kennedy, Margaret M; Tem, Vincent V; Ho, Yu-Jui YJ; Leibold, Josef J; Paffenholz, Stella V SV; Barriga, Francisco M FM; Chu, Kevan K; Goswami, Sukanya S; Wuest, Alexandra N AN; Simon, Janelle M JM; Tsanov, Kaloyan M KM; Chakravarty, Debyani D; Zhang, Hongxin H; Leslie, Christina S CS; Lowe, Scott W SW; Dow, Lukas E LE

Publication Date: 2022-06

Variant appearance in text: TP53: E51K

PubMed Link: 35165384

Variant Present in the following documents:

• NIHMS1760571-supplement-Supplementary_Table_S7.xlsx, sheet 5

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: E51K

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

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Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis.

Plos Medicine

Natrajan, Rachael R; Sailem, Heba H; Mardakheh, Faraz K FK; Arias Garcia, Mar M; Tape, Christopher J CJ; Dowsett, Mitch M; Bakal, Chris C; Yuan, Yinyin Y

Publication Date: 2016-02

Variant appearance in text: TP53: 151G>A

PubMed Link: 26881778

Variant Present in the following documents:

• pmed.1001961.s013.pdf

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Dual-site interactions of p53 protein transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways.

The Journal Of Biological Chemistry

Ha, Ji-Hyang JH; Shin, Jae-Sun JS; Yoon, Mi-Kyung MK; Lee, Min-Sung MS; He, Fahu F; Bae, Kwang-Hee KH; Yoon, Ho Sup HS; Lee, Chong-Kil CK; Park, Sung Goo SG; Muto, Yutaka Y; Chi, Seung-Wook SW

Publication Date: 2013-03-08

Variant appearance in text: p53: E51K

PubMed Link: 23316052

Variant Present in the following documents:

• Main text

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Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Rajagopalan, Sridharan S; Andreeva, Antonina A; Rutherford, Trevor J TJ; Fersht, Alan R AR

Publication Date: 2010-05-11

Variant appearance in text: p53: E51K

PubMed Link: 20421506

Variant Present in the following documents:

• Main text

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Interaction between the transactivation domain of p53 and PC4 exemplifies acidic activation domains as single-stranded DNA mimics.

The Journal Of Biological Chemistry

Rajagopalan, Sridharan S; Andreeva, Antonina A; Teufel, Daniel P DP; Freund, Stefan M SM; Fersht, Alan R AR

Publication Date: 2009-08-07

Variant appearance in text: p53: E51K

PubMed Link: 19525231

Variant Present in the following documents:

• Main text
• zbc21728.pdf

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