TP53 c.150T>C ;(p.I50=)

Variant ID: 17-7579537-A-G

NM_000546.5(TP53):c.150T>C;(p.I50=)

This variant was identified in 13 publications

View GRCh38 version.




Publications:


Tirbanibulin for Actinic Keratosis: Insights into the Mechanism of Action.

Clinical, Cosmetic And Investigational Dermatology
Schlesinger, Todd T; Stockfleth, Eggert E; Grada, Ayman A; Berman, Brian B
Publication Date: 2022

Variant appearance in text: p53: I50=
PubMed Link: 36415541
Variant Present in the following documents:
  • ccid-15-2495.pdf
View BVdb publication page



JAK-STAT signaling in inflammatory breast cancer enables chemotherapy-resistant cell states.

Cancer Research
Stevens, Laura E LE; Peluffo, Guillermo G; Qiu, Xintao X; Temko, Daniel D; Fassl, Anne A; Li, Zheqi Z; Trinh, Anne A; Seehawer, Marco M; Jovanovic, Bojana B; Aleckovic, Masa M; Wilde, Callahan M CM; Geck, Renee C RC; Shu, Shaokun S; Kingston, Natalie L NL; Harper, Nicholas W NW; Almendro, Vanessa V; Pyke, Alanna L AL; Egri, Shawn B SB; Papanastasiou, Malvina M; Clement, Kendell K; Zhou, Ningxuan N; Walker, Sarah S; Salas, Jacqueline J; Park, So Yeon SY; Frank, David A DA; Meissner, Alexander A; Jaffe, Jacob D JD; Sicinski, Piotr P; Toker, Alex A; Michor, Franziska F; Long, Henry W HW; Overmoyer, Beth A BA; Polyak, Kornelia K
Publication Date: 2022-11-21

Variant appearance in text: TP53: I50I
PubMed Link: 36409824
Variant Present in the following documents:
  • can-22-0423_supplementary_table_s3_suppst3.xlsx, sheet 1
View BVdb publication page



Filtering of the Gene Signature as the Predictors of Cisplatin-Resistance in Ovarian Cancer.

Iranian Journal Of Biotechnology
Ataei, Atousa A; Arab, Seyed Shahriar SS; Zahiri, Javad J; Rajabpour, Azam A; Kletenkov, Konstantin K; Rizvanov, Albert A
Publication Date: 2021-07

Variant appearance in text: p53: I50=
PubMed Link: 34825010
Variant Present in the following documents:
  • Main text
  • IJB-19-e2643.pdf
View BVdb publication page



Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells.

Embo Molecular Medicine
Prieto-Garcia, Cristian C; Hartmann, Oliver O; Reissland, Michaela M; Braun, Fabian F; Fischer, Thomas T; Walz, Susanne S; Schülein-Völk, Christina C; Eilers, Ursula U; Ade, Carsten P CP; Calzado, Marco A MA; Orian, Amir A; Maric, Hans M HM; Münch, Christian C; Rosenfeldt, Mathias M; Eilers, Martin M; Diefenbacher, Markus E ME
Publication Date: 2020-04-07

Variant appearance in text: p53: I50=
PubMed Link: 32128997
Variant Present in the following documents:
  • EMMM-12-e11101.pdf
  • EMMM-12-e11101-s002.pdf
View BVdb publication page



Mutational processes shape the landscape of TP53 mutations in human cancer.

Nature Genetics
Giacomelli, Andrew O AO; Yang, Xiaoping X; Lintner, Robert E RE; McFarland, James M JM; Duby, Marc M; Kim, Jaegil J; Howard, Thomas P TP; Takeda, David Y DY; Ly, Seav Huong SH; Kim, Eejung E; Gannon, Hugh S HS; Hurhula, Brian B; Sharpe, Ted T; Goodale, Amy A; Fritchman, Briana B; Steelman, Scott S; Vazquez, Francisca F; Tsherniak, Aviad A; Aguirre, Andrew J AJ; Doench, John G JG; Piccioni, Federica F; Roberts, Charles W M CWM; Meyerson, Matthew M; Getz, Gad G; Johannessen, Cory M CM; Root, David E DE; Hahn, William C WC
Publication Date: 2018-10

Variant appearance in text: TP53: I50I
PubMed Link: 30224644
Variant Present in the following documents:
  • NIHMS1501645-supplement-4.xlsx, sheet 1
View BVdb publication page



Germ-line and somatic EPHA2 coding variants in lens aging and cataract.

Plos One
Bennett, Thomas M TM; M'Hamdi, Oussama O; Hejtmancik, J Fielding JF; Shiels, Alan A
Publication Date: 2017

Variant appearance in text: TP53: I50I
PubMed Link: 29267365
Variant Present in the following documents:
  • pone.0189881.s008.xlsx, sheet 1
View BVdb publication page



Succinamide derivatives of melampomagnolide B and their anti-cancer activities.

Bioorganic & Medicinal Chemistry
Janganati, Venumadhav V; Ponder, Jessica J; Thakkar, Shraddha S; Jordan, Craig T CT; Crooks, Peter A PA
Publication Date: 2017-07-15

Variant appearance in text: p53: I50=
PubMed Link: 28545815
Variant Present in the following documents:
  • Main text
View BVdb publication page



Characterization of the Indirubin Derivative LDD970 as a Small Molecule Aurora Kinase A Inhibitor in Human Colorectal Cancer Cells.

Immune Network
Ndolo, Karyn Muzinga KM; Park, Kyeong Ryang KR; Lee, Hyo Jeong HJ; Yoon, Kyoung Bin KB; Kim, Yong-Chul YC; Han, Sun-Young SY
Publication Date: 2017-04

Variant appearance in text: p53: I50=
PubMed Link: 28458622
Variant Present in the following documents:
  • in-17-110.pdf
View BVdb publication page



Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11.

Nature Chemical Biology
Li, Jing J; Yakushi, Tanya T; Parlati, Francesco F; Mackinnon, Andrew L AL; Perez, Christian C; Ma, Yuyong Y; Carter, Kyle P KP; Colayco, Sharon S; Magnuson, Gavin G; Brown, Brock B; Nguyen, Kevin K; Vasile, Stefan S; Suyama, Eigo E; Smith, Layton H LH; Sergienko, Eduard E; Pinkerton, Anthony B AB; Chung, Thomas D Y TDY; Palmer, Amy E AE; Pass, Ian I; Hess, Sonja S; Cohen, Seth M SM; Deshaies, Raymond J RJ
Publication Date: 2017-05

Variant appearance in text: p53: I50=
PubMed Link: 28244987
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecules that target nucleophosmin for cancer treatment: an update.

Oncotarget
Di Matteo, Adele A; Franceschini, Mimma M; Chiarella, Sara S; Rocchio, Serena S; Travaglini-Allocatelli, Carlo C; Federici, Luca L
Publication Date: 2016-07-12

Variant appearance in text: p53: I50=
PubMed Link: 27058426
Variant Present in the following documents:
  • Main text
View BVdb publication page



Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia.

Oncotarget
Sun, Haibo H; Lin, De-Chen DC; Guo, Xiao X; Kharabi Masouleh, Behzad B; Gery, Sigal S; Cao, Qi Q; Alkan, Serhan S; Ikezoe, Takayuki T; Akiba, Chie C; Paquette, Ronald R; Chien, Wenwen W; Müller-Tidow, Carsten C; Jing, Yang Y; Agelopoulos, Konstantin K; Müschen, Markus M; Koeffler, H Phillip HP
Publication Date: 2016-04-05

Variant appearance in text: p53: I50=
PubMed Link: 26934650
Variant Present in the following documents:
  • oncotarget-07-18736.pdf
View BVdb publication page



Aurora kinases in childhood acute leukemia: the promise of aurora B as therapeutic target.

Leukemia
Hartsink-Segers, S A SA; Zwaan, C M CM; Exalto, C C; Luijendijk, M W J MW; Calvert, V S VS; Petricoin, E F EF; Evans, W E WE; Reinhardt, D D; de Haas, V V; Hedtjärn, M M; Hansen, B R BR; Koch, T T; Caron, H N HN; Pieters, R R; Den Boer, M L ML
Publication Date: 2013-03

Variant appearance in text: p53: I50=
PubMed Link: 22940834
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular mechanisms of action and prediction of response to oxaliplatin in colorectal cancer cells.

British Journal Of Cancer
Arango, D D; Wilson, A J AJ; Shi, Q Q; Corner, G A GA; Arañes, M J MJ; Nicholas, C C; Lesser, M M; Mariadason, J M JM; Augenlicht, L H LH
Publication Date: 2004-11-29

Variant appearance in text: p53: I50=
PubMed Link: 15545975
Variant Present in the following documents:
  • 91-6602215a.pdf
View BVdb publication page