TP53 c.148_149delinsGC ;(p.I50A)

Variant ID: 17-7579538-AT-GC

NM_000546.5(TP53):c.148_149delinsGC;(p.I50A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Structural Basis for the Interaction between p53 Transactivation Domain and the Mediator Subunit MED25.

Molecules (Basel, Switzerland)
Lee, Min-Sung MS; Lim, Kyungeun K; Lee, Mi-Kyung MK; Chi, Seung-Wook SW
Publication Date: 2018-10-22

Variant appearance in text: p53: I50A
PubMed Link: 30360415
Variant Present in the following documents:
  • Main text
  • molecules-23-02726.pdf
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Adaptive patterns in the p53 protein sequence of the hypoxia- and cancer-tolerant blind mole rat Spalax.

Bmc Evolutionary Biology
Domankevich, Vered V; Opatowsky, Yarden Y; Malik, Assaf A; Korol, Abraham B AB; Frenkel, Zeev Z; Manov, Irena I; Avivi, Aaron A; Shams, Imad I
Publication Date: 2016-09-02

Variant appearance in text: p53: I50A
PubMed Link: 27590526
Variant Present in the following documents:
  • Main text
  • 12862_2016_Article_743.pdf
View BVdb publication page



Quality control in oocytes by p63 is based on a spring-loaded activation mechanism on the molecular and cellular level.

Elife
Coutandin, Daniel D; Osterburg, Christian C; Srivastav, Ratnesh Kumar RK; Sumyk, Manuela M; Kehrloesser, Sebastian S; Gebel, Jakob J; Tuppi, Marcel M; Hannewald, Jens J; Schäfer, Birgit B; Salah, Eidarus E; Mathea, Sebastian S; Müller-Kuller, Uta U; Doutch, James J; Grez, Manuel M; Knapp, Stefan S; Dötsch, Volker V
Publication Date: 2016-03-14

Variant appearance in text: p53: I50A
PubMed Link: 27021569
Variant Present in the following documents:
  • Main text
  • elife-13909.pdf
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Characterization of the p300 Taz2-p53 TAD2 complex and comparison with the p300 Taz2-p53 TAD1 complex.

Biochemistry
Miller Jenkins, Lisa M LM; Feng, Hanqiao H; Durell, Stewart R SR; Tagad, Harichandra D HD; Mazur, Sharlyn J SJ; Tropea, Joseph E JE; Bai, Yawen Y; Appella, Ettore E
Publication Date: 2015-03-24

Variant appearance in text: p53: I50A
PubMed Link: 25753752
Variant Present in the following documents:
  • Main text
View BVdb publication page



Mapping the physical and functional interactions between the tumor suppressors p53 and BRCA2.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Rajagopalan, Sridharan S; Andreeva, Antonina A; Rutherford, Trevor J TJ; Fersht, Alan R AR
Publication Date: 2010-05-11

Variant appearance in text: p53: I50A
PubMed Link: 20421506
Variant Present in the following documents:
  • Main text
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Interaction between the transactivation domain of p53 and PC4 exemplifies acidic activation domains as single-stranded DNA mimics.

The Journal Of Biological Chemistry
Rajagopalan, Sridharan S; Andreeva, Antonina A; Teufel, Daniel P DP; Freund, Stefan M SM; Fersht, Alan R AR
Publication Date: 2009-08-07

Variant appearance in text: p53: I50A
PubMed Link: 19525231
Variant Present in the following documents:
  • Main text
  • zbc21728.pdf
View BVdb publication page