TP53 c.146A>C ;(p.D49A)

Variant ID: 17-7579541-T-G

NM_000546.5(TP53):c.146A>C;(p.D49A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: D49A
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
View BVdb publication page



Structure of the E6/E6AP/p53 complex required for HPV-mediated degradation of p53.

Nature
Martinez-Zapien, Denise D; Ruiz, Francesc Xavier FX; Poirson, Juline J; Mitschler, André A; Ramirez, Juan J; Forster, Anne A; Cousido-Siah, Alexandra A; Masson, Murielle M; Vande Pol, Scott S; Podjarny, Alberto A; Travé, Gilles G; Zanier, Katia K
Publication Date: 2016-01-28

Variant appearance in text: p53: D49A
PubMed Link: 26789255
Variant Present in the following documents:
  • Main text
  • nihms740729.pdf
View BVdb publication page



Dual-site interactions of p53 protein transactivation domain with anti-apoptotic Bcl-2 family proteins reveal a highly convergent mechanism of divergent p53 pathways.

The Journal Of Biological Chemistry
Ha, Ji-Hyang JH; Shin, Jae-Sun JS; Yoon, Mi-Kyung MK; Lee, Min-Sung MS; He, Fahu F; Bae, Kwang-Hee KH; Yoon, Ho Sup HS; Lee, Chong-Kil CK; Park, Sung Goo SG; Muto, Yutaka Y; Chi, Seung-Wook SW
Publication Date: 2013-03-08

Variant appearance in text: p53: D49A
PubMed Link: 23316052
Variant Present in the following documents:
  • Main text
View BVdb publication page



Protein L-isoaspartyl methyltransferase regulates p53 activity.

Nature Communications
Lee, Jae-Cheol JC; Kang, Sung-Ung SU; Jeon, Yeji Y; Park, Jong Woo JW; You, Jueng-Soo JS; Ha, Shin-Won SW; Bae, Narkhyun N; Lubec, Gert G; Kwon, So Hee SH; Lee, Ju-Seog JS; Cho, Eun-Jung EJ; Han, Jeung-Whan JW
Publication Date: 2012-06-26

Variant appearance in text: p53: D49A
PubMed Link: 22735455
Variant Present in the following documents:
  • Main text
  • ncomms1933.pdf
View BVdb publication page



Structure of the p53 transactivation domain in complex with the nuclear receptor coactivator binding domain of CREB binding protein.

Biochemistry
Lee, Chul Won CW; Martinez-Yamout, Maria A MA; Dyson, H Jane HJ; Wright, Peter E PE
Publication Date: 2010-11-23

Variant appearance in text: p53: D49A
PubMed Link: 20961098
Variant Present in the following documents:
  • Main text
View BVdb publication page



Human papillomaviruses activate caspases upon epithelial differentiation to induce viral genome amplification.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Moody, Cary A CA; Fradet-Turcotte, Amelie A; Archambault, Jacques J; Laimins, Laimonis A LA
Publication Date: 2007-12-04

Variant appearance in text: p53: D49A
PubMed Link: 18048335
Variant Present in the following documents:
  • Main text
View BVdb publication page