TP53 c.144del ;(p.D48Efs*75)

Variant ID: 17-7579543-CG-C

NM_000546.5(TP53):c.144del;(p.D48Efs*75)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Molecular Testing in Patients With Castration-Resistant Prostate Cancer and Its Impact on Clinical Decision Making.

Jco Precision Oncology
Tao, Derrick L DL; Bailey, Shawna S; Beer, Tomasz M TM; Foss, Erik E; Beckett, Brooke B; Fung, Alice A; Foster, Bryan R BR; Guimaraes, Alexander A; Cetnar, Jeremy P JP; Graff, Julie N JN; Eilers, Kristine M KM; Small, Eric J EJ; Corless, Christopher L CL; Thomas, George V GV; Alumkal, Joshi J JJ
Publication Date: 2017

Variant appearance in text: TP53: D48fs*75
PubMed Link: 31650098
Variant Present in the following documents:
  • Main text
View BVdb publication page



NOTCH, ASCL1, p53 and RB alterations define an alternative pathway driving neuroendocrine and small cell lung carcinomas.

International Journal Of Cancer
Meder, Lydia L; König, Katharina K; Ozretić, Luka L; Schultheis, Anne M AM; Ueckeroth, Frank F; Ade, Carsten P CP; Albus, Kerstin K; Boehm, Diana D; Rommerscheidt-Fuss, Ursula U; Florin, Alexandra A; Buhl, Theresa T; Hartmann, Wolfgang W; Wolf, Jürgen J; Merkelbach-Bruse, Sabine S; Eilers, Martin M; Perner, Sven S; Heukamp, Lukas C LC; Buettner, Reinhard R
Publication Date: 2016-02-15

Variant appearance in text: TP53: 144delC; D48fs
PubMed Link: 26340530
Variant Present in the following documents:
  • IJC-138-927-s005.xlsx, sheet 2
  • IJC-138-927-s005.xlsx, sheet 1
View BVdb publication page



Aurora kinase-C-T191D is constitutively active mutant.

Bmc Cell Biology
Khan, Jabbar J; Khan, Sanaullah S; Attaullah, Sobia S; Ali, Ijaz I; Khan, Shahid Niaz SN
Publication Date: 2012-03-26

Variant appearance in text: p53: 144delC
PubMed Link: 22443468
Variant Present in the following documents:
  • 1471-2121-13-8.pdf
View BVdb publication page