Publications:

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Withaferin A: A Pleiotropic Anticancer Agent from the Indian Medicinal Plant Withania somnifera (L.) Dunal.

Pharmaceuticals (Basel, Switzerland)

Kumar, Suneel S; Mathew, Stephen O SO; Aharwal, Ravindra Prasad RP; Tulli, Hardeep Singh HS; Mohan, Chakrabhavi Dhananjaya CD; Sethi, Gautam G; Ahn, Kwang-Seok KS; Webber, Kassidy K; Sandhu, Sardul Singh SS; Bishayee, Anupam A

Publication Date: 2023-01-22

Variant appearance in text: p53: S46P

PubMed Link: 37259311

Variant Present in the following documents:

• Main text

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ESR1 gene amplification and MAP3K mutations are selected during adjuvant endocrine therapies in relapsing Hormone Receptor-positive, HER2-negative breast cancer (HR+ HER2- BC).

Plos Genetics

Ferrando, Lorenzo L; Vingiani, Andrea A; Garuti, Anna A; Vernieri, Claudio C; Belfiore, Antonino A; Agnelli, Luca L; Dagrada, Gianpaolo G; Ivanoiu, Diana D; Bonizzi, Giuseppina G; Munzone, Elisabetta E; Lippolis, Luana L; Dameri, Martina M; Ravera, Francesco F; Colleoni, Marco M; Viale, Giuseppe G; Magnani, Luca L; Ballestrero, Alberto A; Zoppoli, Gabriele G; Pruneri, Giancarlo G

Publication Date: 2023-01-03

Variant appearance in text: rs876659630

PubMed Link: 36595552

Variant Present in the following documents:

• pgen.1010563.s004.xlsx, sheet 1

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Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics

G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A

Publication Date: 2022

Variant appearance in text: rs876659630

PubMed Link: 36561320

Variant Present in the following documents:

• Table2.xlsx, sheet 7

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Coordination of the AMPK, Akt, mTOR, and p53 Pathways under Glucose Starvation.

International Journal Of Molecular Sciences

Zhou, Yifan Y; Liu, Feng F

Publication Date: 2022-11-29

Variant appearance in text: p53: S46P

PubMed Link: 36499271

Variant Present in the following documents:

• ijms-23-14945.pdf

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Comparative computational and experimental analyses of some natural small molecules to restore transcriptional activation function of p53 in cancer cells harbouring wild type and p53Ser46 mutant.

Current Research In Structural Biology

Shefrin, Seyad S; Sari, Anissa Nofita AN; Kumar, Vipul V; Zhang, Huayue H; Meidinna, Hazna Noor HN; Kaul, Sunil C SC; Wadhwa, Renu R; Sundar, Durai D

Publication Date: 2022

Variant appearance in text: p53: S46P

PubMed Link: 36164647

Variant Present in the following documents:

• Main text

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: p53: 136T>C

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

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Clinical relevance of molecular characteristics in Burkitt lymphoma differs according to age.

Nature Communications

Burkhardt, Birgit B; Michgehl, Ulf U; Rohde, Jonas J; Erdmann, Tabea T; Berning, Philipp P; Reutter, Katrin K; Rohde, Marius M; Borkhardt, Arndt A; Burmeister, Thomas T; Dave, Sandeep S; Tzankov, Alexandar A; Dugas, Martin M; Sandmann, Sarah S; Fend, Falko F; Finger, Jasmin J; Mueller, Stephanie S; Gökbuget, Nicola N; Haferlach, Torsten T; Kern, Wolfgang W; Hartmann, Wolfgang W; Klapper, Wolfram W; Oschlies, Ilske I; Richter, Julia J; Kontny, Udo U; Lutz, Mathias M; Maecker-Kolhoff, Britta B; Ott, German G; Rosenwald, Andreas A; Siebert, Reiner R; von Stackelberg, Arend A; Strahm, Brigitte B; Woessmann, Wilhelm W; Zimmermann, Martin M; Zapukhlyak, Myroslav M; Grau, Michael M; Lenz, Georg G

Publication Date: 2022-07-06

Variant appearance in text: TP53: 136T>C

PubMed Link: 35794096

Variant Present in the following documents:

• 41467_2022_31355_MOESM5_ESM.xlsx, sheet 2

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A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports

Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM

Publication Date: 2021-07-12

Variant appearance in text: TP53: S46P; rs876659630

PubMed Link: 34253785

Variant Present in the following documents:

• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 4
• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 6
• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 8
• 41598_2021_93715_MOESM3_ESM.xlsx, sheet 2

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Defining relative mutational difficulty to understand cancer formation.

Cell Discovery

Shan, Lin L; Yu, Jiao J; He, Zhengjin Z; Chen, Shishuang S; Liu, Mingxian M; Ding, Hongyu H; Xu, Liang L; Zhao, Jie J; Yang, Ailing A; Jiang, Hai H

Publication Date: 2020

Variant appearance in text: p53: S46P

PubMed Link: 32704382

Variant Present in the following documents:

• 41421_2020_177_MOESM4_ESM.xlsx, sheet 1

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N6-methyladenosine mediates arsenite-induced human keratinocyte transformation by suppressing p53 activation.

Environmental Pollution (Barking, Essex : 1987)

Zhao, Tianhe T; Sun, Donglei D; Zhao, Manyu M; Lai, Yanhao Y; Liu, Yuan Y; Zhang, Zunzhen Z

Publication Date: 2020-04

Variant appearance in text: p53: S46P

PubMed Link: 31931413

Variant Present in the following documents:

• Main text

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From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.

Cold Spring Harbor Molecular Case Studies

Quinn, Emily A EA; Maciaszek, Jamie L JL; Pinto, Emilia M EM; Phillips, Aaron H AH; Berdy, David D; Khandwala, Mohammad M; Upadhyaya, Santhosh A SA; Zambetti, Gerard P GP; Kriwacki, Richard W RW; Ellison, David W DW; Nichols, Kim E KE; Kesserwan, Chimene C

Publication Date: 2019-08

Variant appearance in text: TP53: 136T>C; Ser46Pro

PubMed Link: 30886117

Variant Present in the following documents:

• supp_mcs.a003921_Supplemental_Table_1a.xlsx, sheet 1

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HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription.

Retrovirology

Ivanov, Andrey A; Lin, Xionghao X; Ammosova, Tatiana T; Ilatovskiy, Andrey V AV; Kumari, Namita N; Lassiter, Hatajai H; Afangbedji, Nowah N; Niu, Xiaomei X; Petukhov, Michael G MG; Nekhai, Sergei S

Publication Date: 2018-05-23

Variant appearance in text: p53: S46P

PubMed Link: 29792216

Variant Present in the following documents:

• Main text
• 12977_2018_Article_422.pdf

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CDK16 Phosphorylates and Degrades p53 to Promote Radioresistance and Predicts Prognosis in Lung Cancer.

Theranostics

Xie, Jie J; Li, Yan Y; Jiang, Ke K; Hu, Kaishun K; Zhang, Sheng S; Dong, Xiaorong X; Dai, Xiaofang X; Liu, Li L; Zhang, Tao T; Yang, Kunyu K; Huang, Kai K; Chen, Junjie J; Shi, Shaojun S; Zhang, Yu Y; Wu, Gang G; Xu, Shuangbing S

Publication Date: 2018

Variant appearance in text: p53: S46P

PubMed Link: 29344296

Variant Present in the following documents:

• Main text
• thnov08p0650.pdf

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Otub1 stabilizes MDMX and promotes its proapoptotic function at the mitochondria.

Oncotarget

Chen, Yingxiao Y; Wang, Yue-Gang YG; Li, Yuhuang Y; Sun, Xiao-Xin XX; Dai, Mu-Shui MS

Publication Date: 2017-02-14

Variant appearance in text: p53: S46P

PubMed Link: 28035068

Variant Present in the following documents:

• Main text
• oncotarget-08-11053.pdf

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: S46P

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

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Negative Regulation of p21Waf1/Cip1 by Human INO80 Chromatin Remodeling Complex Is Implicated in Cell Cycle Phase G2/M Arrest and Abnormal Chromosome Stability.

Plos One

Cao, Lingling L; Ding, Jian J; Dong, Liguo L; Zhao, Jiayao J; Su, Jiaming J; Wang, Lingyao L; Sui, Yi Y; Zhao, Tong T; Wang, Fei F; Jin, Jingji J; Cai, Yong Y

Publication Date: 2015

Variant appearance in text: p53: S46p

PubMed Link: 26340092

Variant Present in the following documents:

• Main text
• pone.0137411.pdf

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: TP53: S46P

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 1

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Whole-genome resequencing analyses of five pig breeds, including Korean wild and native, and three European origin breeds.

Dna Research : An International Journal For Rapid Publication Of Reports On Genes And Genomes

Choi, Jung-Woo JW; Chung, Won-Hyong WH; Lee, Kyung-Tai KT; Cho, Eun-Seok ES; Lee, Si-Woo SW; Choi, Bong-Hwan BH; Lee, Sang-Heon SH; Lim, Wonjun W; Lim, Dajeong D; Lee, Yun-Gyeong YG; Hong, Joon-Ki JK; Kim, Doo-Wan DW; Jeon, Hyeon-Jeong HJ; Kim, Jiwoong J; Kim, Namshin N; Kim, Tae-Hun TH

Publication Date: 2015-08

Variant appearance in text: p53: S46P

PubMed Link: 26117497

Variant Present in the following documents:

• supp_dsv011_dsv011supp_table2.xlsx, sheet 2

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Genetic diversity of newly diagnosed follicular lymphoma.

Blood Cancer Journal

Asmann, Y W YW; Maurer, M J MJ; Wang, C C; Sarangi, V V; Ansell, S M SM; Feldman, A L AL; Nowakowski, G S GS; Manske, M M; Price-Troska, T T; Yang, Z-Z ZZ; Slager, S L SL; Habermann, T M TM; Cerhan, J R JR; Novak, A J AJ

Publication Date: 2014-10-31

Variant appearance in text: TP53: 136T>C

PubMed Link: 25360902

Variant Present in the following documents:

• bcj201480x6.xls, sheet 1

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: S46P

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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Interaction between transactivation domain of p53 and middle part of TBP-like protein (TLP) is involved in TLP-stimulated and p53-activated transcription from the p21 upstream promoter.

Plos One

Maeda, Ryo R; Suzuki, Hidefumi H; Tanaka, Yuta Y; Tamura, Taka-aki TA

Publication Date: 2014

Variant appearance in text: p53: S46P

PubMed Link: 24594805

Variant Present in the following documents:

• Main text
• pone.0090190.pdf

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Predicting the functional impact of protein mutations: application to cancer genomics.

Nucleic Acids Research

Reva, Boris B; Antipin, Yevgeniy Y; Sander, Chris C

Publication Date: 2011-09-01

Variant appearance in text: TP53: S46P

PubMed Link: 21727090

Variant Present in the following documents:

• supp_gkr407_Supplement2_Table_SM1_COSMIC_mutations.xls, sheet 1

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Pharmacological activation of a novel p53-dependent S-phase checkpoint involving CHK-1.

Cell Death & Disease

Ahmed, A A; Yang, J J; Maya-Mendoza, A A; Jackson, D A DA; Ashcroft, M M

Publication Date: 2011-05-19

Variant appearance in text: p53: S46P

PubMed Link: 21593792

Variant Present in the following documents:

• Main text

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