TP53 c.109T>C ;(p.S37P)

Variant ID: 17-7579578-A-G

NM_000546.5(TP53):c.109T>C;(p.S37P)

This variant was identified in 15 publications

View GRCh38 version.




Publications:


Combination CDC-like kinase inhibition (CLK)/Dual-specificity tyrosine-regulated kinase (DYRK) and taxane therapy in CTNNB1 -mutated endometrial cancer.

Biorxiv : The Preprint Server For Biology
Corr, Bradley R BR; Moroney, Marisa R MR; Woodruff, Elizabeth E; Watson, Zachary L ZL; Jordan, Kimberly R KR; Danhorn, Thomas T; Bailey, Courtney C; Wolsky, Rebecca J RJ; Bitler, Benjamin G BG
Publication Date: 2023-04-06

Variant appearance in text: TP53: S37P
PubMed Link: 37066339
Variant Present in the following documents:
  • media-2.xlsx, sheet 1
View BVdb publication page



Plasma ctDNA increases tissue NGS-based detection of therapeutically targetable mutations in lung cancers.

Bmc Cancer
Xie, Jianjiang J; Yao, Weishen W; Chen, Lingxiu L; Zhu, Wenjun W; Liu, Qiang Q; Geng, Geng G; Fang, Jing J; Zhao, Yang Y; Xiao, Li L; Huang, Zhenhua Z; Zhao, Jing J
Publication Date: 2023-03-31

Variant appearance in text: TP53: Ser37Pro
PubMed Link: 37004022
Variant Present in the following documents:
  • 12885_2023_10674_MOESM3_ESM.xlsx, sheet 1
View BVdb publication page



The GSK-3β-FBXL21 Axis Contributes to Circadian TCAP Degradation and Skeletal Muscle Function.

Cell Reports
Wirianto, Marvin M; Yang, Jiah J; Kim, Eunju E; Gao, Song S; Paudel, Keshav Raj KR; Choi, Jong Min JM; Choe, Jeehwan J; Gloston, Gabrielle F GF; Ademoji, Precious P; Parakramaweera, Randika R; Jin, Jianping J; Esser, Karyn A KA; Jung, Sung Yun SY; Geng, Yong-Jian YJ; Lee, Hyun Kyoung HK; Chen, Zheng Z; Yoo, Seung-Hee SH
Publication Date: 2020-09-15

Variant appearance in text: p53: S37p
PubMed Link: 32937135
Variant Present in the following documents:
  • nihms-1629510.pdf
View BVdb publication page



Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology
Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR
Publication Date: 2019-04

Variant appearance in text: TP53: S37P
PubMed Link: 31034466
Variant Present in the following documents:
  • pcbi.1006981.s010.xlsx, sheet 1
View BVdb publication page



Germ-line and somatic EPHA2 coding variants in lens aging and cataract.

Plos One
Bennett, Thomas M TM; M'Hamdi, Oussama O; Hejtmancik, J Fielding JF; Shiels, Alan A
Publication Date: 2017

Variant appearance in text: TP53: S37P
PubMed Link: 29267365
Variant Present in the following documents:
  • pone.0189881.s007.xlsx, sheet 2
  • pone.0189881.s007.xlsx, sheet 3
  • pone.0189881.s007.xlsx, sheet 4
  • pone.0189881.s007.xlsx, sheet 1
View BVdb publication page



The whole-genome landscape of medulloblastoma subtypes.

Nature
Northcott, Paul A PA; Buchhalter, Ivo I; Morrissy, A Sorana AS; Hovestadt, Volker V; Weischenfeldt, Joachim J; Ehrenberger, Tobias T; Gröbner, Susanne S; Segura-Wang, Maia M; Zichner, Thomas T; Rudneva, Vasilisa A VA; Warnatz, Hans-Jörg HJ; Sidiropoulos, Nikos N; Phillips, Aaron H AH; Schumacher, Steven S; Kleinheinz, Kortine K; Waszak, Sebastian M SM; Erkek, Serap S; Jones, David T W DTW; Worst, Barbara C BC; Kool, Marcel M; Zapatka, Marc M; Jäger, Natalie N; Chavez, Lukas L; Hutter, Barbara B; Bieg, Matthias M; Paramasivam, Nagarajan N; Heinold, Michael M; Gu, Zuguang Z; Ishaque, Naveed N; Jäger-Schmidt, Christina C; Imbusch, Charles D CD; Jugold, Alke A; Hübschmann, Daniel D; Risch, Thomas T; Amstislavskiy, Vyacheslav V; Gonzalez, Francisco German Rodriguez FGR; Weber, Ursula D UD; Wolf, Stephan S; Robinson, Giles W GW; Zhou, Xin X; Wu, Gang G; Finkelstein, David D; Liu, Yanling Y; Cavalli, Florence M G FMG; Luu, Betty B; Ramaswamy, Vijay V; Wu, Xiaochong X; Koster, Jan J; Ryzhova, Marina M; Cho, Yoon-Jae YJ; Pomeroy, Scott L SL; Herold-Mende, Christel C; Schuhmann, Martin M; Ebinger, Martin M; Liau, Linda M LM; Mora, Jaume J; McLendon, Roger E RE; Jabado, Nada N; Kumabe, Toshihiro T; Chuah, Eric E; Ma, Yussanne Y; Moore, Richard A RA; Mungall, Andrew J AJ; Mungall, Karen L KL; Thiessen, Nina N; Tse, Kane K; Wong, Tina T; Jones, Steven J M SJM; Witt, Olaf O; Milde, Till T; Von Deimling, Andreas A; Capper, David D; Korshunov, Andrey A; Yaspo, Marie-Laure ML; Kriwacki, Richard R; Gajjar, Amar A; Zhang, Jinghui J; Beroukhim, Rameen R; Fraenkel, Ernest E; Korbel, Jan O JO; Brors, Benedikt B; Schlesner, Matthias M; Eils, Roland R; Marra, Marco A MA; Pfister, Stefan M SM; Taylor, Michael D MD; Lichter, Peter P
Publication Date: 2017-07-19

Variant appearance in text: TP53: S37P
PubMed Link: 28726821
Variant Present in the following documents:
  • 41586_2017_Article_BFnature22973.pdf
View BVdb publication page



iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: S37P
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
View BVdb publication page



Mutational analysis of single circulating tumor cells by next generation sequencing in metastatic breast cancer.

Oncotarget
De Luca, Francesca F; Rotunno, Giada G; Salvianti, Francesca F; Galardi, Francesca F; Pestrin, Marta M; Gabellini, Stefano S; Simi, Lisa L; Mancini, Irene I; Vannucchi, Alessandro Maria AM; Pazzagli, Mario M; Di Leo, Angelo A; Pinzani, Pamela P
Publication Date: 2016-05-03

Variant appearance in text: TP53: S37P
PubMed Link: 27034166
Variant Present in the following documents:
  • Main text
View BVdb publication page



GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics
Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J
Publication Date: 2015-07-25

Variant appearance in text: TP53: S37P
PubMed Link: 26206375
Variant Present in the following documents:
  • 12859_2015_673_MOESM1_ESM.xls, sheet 1
View BVdb publication page



Clinical Grade "SNaPshot" Genetic Mutation Profiling in Multiple Myeloma.

Ebiomedicine
O'Donnell, Elizabeth E; Mahindra, Anuj A; Yee, Andrew J AJ; Nardi, Valentina V; Birrer, Nicole N; Horick, Nora N; Borger, Darrell D; Finkelstein, Dianne D; Iafrate, John A JA; Raje, Noopur N
Publication Date: 2015-01

Variant appearance in text: TP53: 109T>C; Ser37Pro
PubMed Link: 26137536
Variant Present in the following documents:
  • mmc1.pdf
View BVdb publication page



Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology
Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B
Publication Date: 2014-10-28

Variant appearance in text: TP53: S37P
PubMed Link: 25348012
Variant Present in the following documents:
  • 13059_2014_484_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page



High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.

Nature Communications
Nault, Jean Charles JC; Mallet, Maxime M; Pilati, Camilla C; Calderaro, Julien J; Bioulac-Sage, Paulette P; Laurent, Christophe C; Laurent, Alexis A; Cherqui, Daniel D; Balabaud, Charles C; Zucman-Rossi, Jessica J; Zucman Rossi, Jessica J
Publication Date: 2013

Variant appearance in text: TP53: 109T>C; Ser37Pro
PubMed Link: 23887712
Variant Present in the following documents:
  • ncomms3218-s1.pdf
View BVdb publication page



Loss of BubR1 acetylation causes defects in spindle assembly checkpoint signaling and promotes tumor formation.

The Journal Of Cell Biology
Park, Inai I; Lee, Hae-ock HO; Choi, Eunhee E; Lee, Yoo-Kyung YK; Kwon, Mi-Sun MS; Min, Jaewon J; Park, Pil-Gu PG; Lee, Seonju S; Kong, Young-Yun YY; Gong, Gyungyub G; Lee, Hyunsook H
Publication Date: 2013-07-22

Variant appearance in text: p53: 109T>C
PubMed Link: 23878276
Variant Present in the following documents:
  • Main text
View BVdb publication page



Aurora A mediates cross-talk between N- and C-terminal post-translational modifications of p53.

Cancer Biology & Therapy
Warnock, Lorna Jane LJ; Raines, Sally Anne SA; Milner, Jo J
Publication Date: 2011-12-15

Variant appearance in text: p53: S37P
PubMed Link: 22157150
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tip60 and p400 are both required for UV-induced apoptosis but play antagonistic roles in cell cycle progression.

The Embo Journal
Tyteca, Sandrine S; Vandromme, Marie M; Legube, Gaëlle G; Chevillard-Briet, Martine M; Trouche, Didier D
Publication Date: 2006-04-19

Variant appearance in text: p53: S37P
PubMed Link: 16601686
Variant Present in the following documents:
  • Main text
View BVdb publication page