TP53 c.80C>G ;(p.P27R)

Variant ID: 17-7579716-G-C

NM_000546.5(TP53):c.80C>G;(p.P27R)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Preclinical Head and Neck Squamous Cell Carcinoma Models for Combined Targeted Therapy Approaches.

Cancers
Schoenwaelder, Nina N; Krause, Mareike M; Freitag, Thomas T; Schneider, Björn B; Zonnur, Sarah S; Zimpfer, Annette A; Becker, Anne Sophie AS; Salewski, Inken I; Strüder, Daniel Fabian DF; Lemcke, Heiko H; Grosse-Thie, Christina C; Junghanss, Christian C; Maletzki, Claudia C
Publication Date: 2022-05-18

Variant appearance in text: TP53: P27R
PubMed Link: 35626088
Variant Present in the following documents:
  • Main text
  • cancers-14-02484.pdf
View BVdb publication page



p53 Mediates GnRH Secretion via Lin28/let-7 System in GT1-7 Cells.

Diabetes, Metabolic Syndrome And Obesity : Targets And Therapy
Chen, Ting T; Wu, Haiying H; Chen, Xiuli X; Xie, Rongrong R; Wang, Fengyun F; Sun, Hui H; Chen, Linqi L
Publication Date: 2020

Variant appearance in text: p53: P27R
PubMed Link: 33299335
Variant Present in the following documents:
  • Main text
  • dmso-13-4681.pdf
View BVdb publication page



Genetic predisposition to neural crest-derived tumors: revisiting the role of KIF1B.

Endocrine Connections
Cardot Bauters, Catherine C; Leteurtre, Emmanuelle E; Carnaille, Bruno B; Do Cao, Christine C; Espiard, Stéphanie S; Penven, Malo M; Destailleur, Evelyne E; Szuster, Isabelle I; Lovecchio, Tonio T; Leclerc, Julie J; Frénois, Fredéric F; Esquivel, Emmanuel E; Dahia, Patricia L M PLM; Ait-Yahya, Emilie E; Crépin, Michel M; Pigny, Pascal P
Publication Date: 2020-10

Variant appearance in text: TP53: 80C>G; P27R
PubMed Link: 33112832
Variant Present in the following documents:
  • Main text
  • EC-20-0460.pdf
View BVdb publication page



Promising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts.

International Journal Of Molecular Sciences
Lee, Hye Won HW; Son, Eunju E; Lee, Kyoungmin K; Lee, Yeri Y; Kim, Yejin Y; Lee, Jae-Chul JC; Lim, Yangmi Y; Hur, Minkyu M; Kim, Donggeon D; Nam, Do-Hyun DH
Publication Date: 2019-11-24

Variant appearance in text: TP53: P27R
PubMed Link: 31771279
Variant Present in the following documents:
  • Main text
  • ijms-20-05894.pdf
View BVdb publication page



iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: P27R
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
View BVdb publication page



The indole-3-carbinol cyclic tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines.

Breast Cancer Research : Bcr
De Santi, Mauro M; Galluzzi, Luca L; Lucarini, Simone S; Paoletti, Maria Filomena MF; Fraternale, Alessandra A; Duranti, Andrea A; De Marco, Cinzia C; Fanelli, Mirco M; Zaffaroni, Nadia N; Brandi, Giorgio G; Magnani, Mauro M
Publication Date: 2011-03-24

Variant appearance in text: p53: p27R
PubMed Link: 21435243
Variant Present in the following documents:
  • Main text
  • bcr2855.pdf
View BVdb publication page



Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors.

Plos One
Algar, Elizabeth M EM; Muscat, Andrea A; Dagar, Vinod V; Rickert, Christian C; Chow, C W CW; Biegel, Jaclyn A JA; Ekert, Paul G PG; Saffery, Richard R; Craig, Jeff J; Johnstone, Ricky W RW; Ashley, David M DM
Publication Date: 2009

Variant appearance in text: p53: p27R
PubMed Link: 19221586
Variant Present in the following documents:
  • Main text
  • pone.0004482.pdf
View BVdb publication page