TP53 c.79_80delinsTT ;(p.P27F)

Variant ID: 17-7579716-GG-AA

NM_000546.5(TP53):c.79_80delinsTT;(p.P27F)

This variant was identified in 2 publications

View GRCh38 version.




Publications:


The indole-3-carbinol cyclic tetrameric derivative CTet inhibits cell proliferation via overexpression of p21/CDKN1A in both estrogen receptor-positive and triple-negative breast cancer cell lines.

Breast Cancer Research : Bcr
De Santi, Mauro M; Galluzzi, Luca L; Lucarini, Simone S; Paoletti, Maria Filomena MF; Fraternale, Alessandra A; Duranti, Andrea A; De Marco, Cinzia C; Fanelli, Mirco M; Zaffaroni, Nadia N; Brandi, Giorgio G; Magnani, Mauro M
Publication Date: 2011-03-24

Variant appearance in text: p53: p27F
PubMed Link: 21435243
Variant Present in the following documents:
  • Main text
  • bcr2855.pdf
View BVdb publication page



Imprinted CDKN1C is a tumor suppressor in rhabdoid tumor and activated by restoration of SMARCB1 and histone deacetylase inhibitors.

Plos One
Algar, Elizabeth M EM; Muscat, Andrea A; Dagar, Vinod V; Rickert, Christian C; Chow, C W CW; Biegel, Jaclyn A JA; Ekert, Paul G PG; Saffery, Richard R; Craig, Jeff J; Johnstone, Ricky W RW; Ashley, David M DM
Publication Date: 2009

Variant appearance in text: p53: p27F
PubMed Link: 19221586
Variant Present in the following documents:
  • Main text
  • pone.0004482.pdf
View BVdb publication page