Publications:

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Construction and validation of an immunoediting-based optimized neoantigen load (ioTNL) model to predict the response and prognosis of immune checkpoint therapy in various cancers.

Aging

Su, Xiaofan X; Jin, Haoxuan H; Wang, Jiaqian J; Lu, Huiping H; Gu, Tiantian T; Gao, Zhibo Z; Li, Manxiang M

Publication Date: 2022-05-25

Variant appearance in text: TP53: 79C>G; P27A

PubMed Link: 35613927

Variant Present in the following documents:

• aging-14-204101-s004.xlsx, sheet 1

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Cancer genomic profiling identified dihydropyrimidine dehydrogenase deficiency in bladder cancer promotes sensitivity to gemcitabine.

Scientific Reports

Tsukahara, Shigehiro S; Shiota, Masaki M; Takamatsu, Dai D; Nagakawa, Shohei S; Matsumoto, Takashi T; Kiyokoba, Ryo R; Yagi, Mikako M; Setoyama, Daiki D; Noda, Nozomi N; Matsumoto, Shinya S; Hayashi, Tetsutaro T; Contreras-Sanz, Alberto A; Black, Peter C PC; Inokuchi, Junichi J; Kohashi, Kenichi K; Oda, Yoshinao Y; Uchiumi, Takeshi T; Eto, Masatoshi M; Kang, Dongchon D

Publication Date: 2022-05-20

Variant appearance in text: TP53: Pro27Ala

PubMed Link: 35595780

Variant Present in the following documents:

• 41598_2022_12528_MOESM2_ESM.pdf

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Rational design of a helical peptide inhibitor targeting c-Myb-KIX interaction.

Scientific Reports

Suetaka, Shunji S; Oka, Yoshiki Y; Kunihara, Tomoko T; Hayashi, Yuuki Y; Arai, Munehito M

Publication Date: 2022-01-20

Variant appearance in text: p53: P27A

PubMed Link: 35058484

Variant Present in the following documents:

• Main text
• 41598_2021_Article_4497.pdf

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Rational design of a helical peptide inhibitor targeting c-Myb-KIX interaction.

Scientific Reports

Suetaka, Shunji S; Oka, Yoshiki Y; Kunihara, Tomoko T; Hayashi, Yuuki Y; Arai, Munehito M

Publication Date: 2022-01-20

Variant appearance in text: p53: P27A

PubMed Link: 35058484

Variant Present in the following documents:

• Main text
• 41598_2021_Article_4497.pdf

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Significant impact of circulating tumour DNA mutations on survival in metastatic breast cancer patients.

Scientific Reports

Muendlein, Axel A; Geiger, Kathrin K; Gaenger, Stella S; Dechow, Tobias T; Nonnenbroich, Christoph C; Leiherer, Andreas A; Drexel, Heinz H; Gaumann, Andreas A; Jagla, Wolfgang W; Winder, Thomas T; Mayer, Frank F; Decker, Thomas T

Publication Date: 2021-03-24

Variant appearance in text: TP53: 79C>G; Pro27Ala

PubMed Link: 33762647

Variant Present in the following documents:

• 41598_2021_86238_MOESM2_ESM.xlsx, sheet 1

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: TP53: 79C>G; P27A

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

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MuRF1/TRIM63, Master Regulator of Muscle Mass.

International Journal Of Molecular Sciences

Peris-Moreno, Dulce D; Taillandier, Daniel D; Polge, Cécile C

Publication Date: 2020-09-11

Variant appearance in text: p53: p27A

PubMed Link: 32933049

Variant Present in the following documents:

• Main text
• ijms-21-06663.pdf

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The Role of Toll-Like Receptors in Oncotherapy.

Oncology Research

Liu, Caiqi C; Han, Ci C; Liu, Jinfeng J

Publication Date: 2019-08-08

Variant appearance in text: p53: P27A

PubMed Link: 30940297

Variant Present in the following documents:

• OR-27-965.pdf

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Using NMR Chemical Shifts to Determine Residue-Specific Secondary Structure Populations for Intrinsically Disordered Proteins.

Methods In Enzymology

Borcherds, Wade M WM; Daughdrill, Gary W GW

Publication Date: 2018

Variant appearance in text: p53: P27A

PubMed Link: 30471686

Variant Present in the following documents:

• Main text

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Bridging Microscopic and Macroscopic Mechanisms of p53-MDM2 Binding with Kinetic Network Models.

Biophysical Journal

Zhou, Guangfeng G; Pantelopulos, George A GA; Mukherjee, Sudipto S; Voelz, Vincent A VA

Publication Date: 2017-08-22

Variant appearance in text: p53: P27A

PubMed Link: 28834715

Variant Present in the following documents:

• Main text

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Conserved Helix-Flanking Prolines Modulate Intrinsically Disordered Protein:Target Affinity by Altering the Lifetime of the Bound Complex.

Biochemistry

Crabtree, Michael D MD; Borcherds, Wade W; Poosapati, Anusha A; Shammas, Sarah L SL; Daughdrill, Gary W GW; Clarke, Jane J

Publication Date: 2017-05-09

Variant appearance in text: p53: P27A

PubMed Link: 28425697

Variant Present in the following documents:

• Main text
• bi7b00179.pdf

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Using chemical shifts to generate structural ensembles for intrinsically disordered proteins with converged distributions of secondary structure.

Intrinsically Disordered Proteins

Ytreberg, F Marty FM; Borcherds, Wade W; Wu, Hongwei H; Daughdrill, Gary W GW

Publication Date: 2015

Variant appearance in text: p53: P27A

PubMed Link: 28232883

Variant Present in the following documents:

• Main text

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: P27A

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

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Loss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos.

Plos One

Hu, Zhilian Z; Holzschuh, Jochen J; Driever, Wolfgang W

Publication Date: 2015

Variant appearance in text: p53: p27a

PubMed Link: 26225764

Variant Present in the following documents:

• Main text

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Structural basis of how stress-induced MDMX phosphorylation activates p53.

Oncogene

Chen, X X; Gohain, N N; Zhan, C C; Lu, W-Y WY; Pazgier, M M; Lu, W W

Publication Date: 2016-04-14

Variant appearance in text: p53: P27A

PubMed Link: 26148237

Variant Present in the following documents:

• Main text

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Molecular dynamic simulation insights into the normal state and restoration of p53 function.

International Journal Of Molecular Sciences

Fu, Ting T; Min, Hanyi H; Xu, Yong Y; Chen, Jianzhong J; Li, Guohui G

Publication Date: 2012

Variant appearance in text: p53: P27A

PubMed Link: 22949826

Variant Present in the following documents:

• Main text
• ijms-13-09709.pdf

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Molecular dynamic simulation insights into the normal state and restoration of p53 function.

International Journal Of Molecular Sciences

Fu, Ting T; Min, Hanyi H; Xu, Yong Y; Chen, Jianzhong J; Li, Guohui G

Publication Date: 2012

Variant appearance in text: p53: P27A

PubMed Link: 22949826

Variant Present in the following documents:

• Main text
• ijms-13-09709.pdf

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C-terminal substitution of MDM2 interacting peptides modulates binding affinity by distinctive mechanisms.

Plos One

Brown, Christopher J CJ; Dastidar, Shubhra G SG; Quah, Soo T ST; Lim, Annie A; Chia, Brian B; Verma, Chandra S CS

Publication Date: 2011

Variant appearance in text: p53: P27A

PubMed Link: 21904608

Variant Present in the following documents:

• Main text
• pone.0024122.pdf

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Systematic mutational analysis of peptide inhibition of the p53-MDM2/MDMX interactions.

Journal Of Molecular Biology

Li, Chong C; Pazgier, Marzena M; Li, Changqing C; Yuan, Weirong W; Liu, Min M; Wei, Gang G; Lu, Wei-Yue WY; Lu, Wuyuan W

Publication Date: 2010-04-30

Variant appearance in text: p53: P27A

PubMed Link: 20226197

Variant Present in the following documents:

• Main text

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