Publications:

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Synthesis of Amino Acids Bearing Halodifluoromethyl Moieties and Their Application to p53-Derived Peptides Binding to Mdm2/Mdm4.

Drug Design, Development And Therapy

Vaas, Sebastian S; Zimmermann, Markus O MO; Klett, Theresa T; Boeckler, Frank M FM

Publication Date: 2023

Variant appearance in text: p53: Lys24Asn

PubMed Link: 37128274

Variant Present in the following documents:

• Main text
• dddt-17-1247.pdf

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The Elephant Evolved p53 Isoforms that Escape MDM2-Mediated Repression and Cancer.

Molecular Biology And Evolution

Padariya, Monikaben M; Jooste, Mia-Lyn ML; Hupp, Ted T; Fåhraeus, Robin R; Vojtesek, Borek B; Vollrath, Fritz F; Kalathiya, Umesh U; Karakostis, Konstantinos K

Publication Date: 2022-07-02

Variant appearance in text: p53: K24N

PubMed Link: 35792674

Variant Present in the following documents:

• Main text
• msac149.pdf

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A High-Throughput Screening System Based on Fluorescence-Activated Cell Sorting for the Directed Evolution of Chitinase A.

International Journal Of Molecular Sciences

Menghiu, Gheorghita G; Ostafe, Vasile V; Prodanović, Radivoje R; Fischer, Rainer R; Ostafe, Raluca R

Publication Date: 2021-03-16

Variant appearance in text: p53: K24N

PubMed Link: 33809788

Variant Present in the following documents:

• ijms-22-03041.pdf

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Implementation of adaptive integration method for free energy calculations in molecular systems.

Peerj. Computer Science

Mirabzadeh, Christopher A CA; Ytreberg, F Marty FM

Publication Date: 2020

Variant appearance in text: p53: K24N

PubMed Link: 33457645

Variant Present in the following documents:

• peerj-cs-06-264.pdf

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Modulation of p53 Transactivation Domain Conformations by Ligand Binding and Cancer-Associated Mutations.

Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing

Liu, Xiaorong X; Chen, Jianhan J

Publication Date: 2020

Variant appearance in text: p53: K24N

PubMed Link: 31797597

Variant Present in the following documents:

• Main text
• nihms-1061356.pdf

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Sequence specificity despite intrinsic disorder: How a disease-associated Val/Met polymorphism rearranges tertiary interactions in a long disordered protein.

Plos Computational Biology

Lohia, Ruchi R; Salari, Reza R; Brannigan, Grace G

Publication Date: 2019-10

Variant appearance in text: p53: K24N

PubMed Link: 31626641

Variant Present in the following documents:

• pcbi.1007390.pdf

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Residual Structures and Transient Long-Range Interactions of p53 Transactivation Domain: Assessment of Explicit Solvent Protein Force Fields.

Journal Of Chemical Theory And Computation

Liu, Xiaorong X; Chen, Jianhan J

Publication Date: 2019-08-13

Variant appearance in text: p53: K24N

PubMed Link: 31241933

Variant Present in the following documents:

• Main text

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Finding driver mutations in cancer: Elucidating the role of background mutational processes.

Plos Computational Biology

Brown, Anna-Leigh AL; Li, Minghui M; Goncearenco, Alexander A; Panchenko, Anna R AR

Publication Date: 2019-04

Variant appearance in text: TP53: K24N

PubMed Link: 31034466

Variant Present in the following documents:

• pcbi.1006981.s010.xlsx, sheet 1

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Detecting protein variants by mass spectrometry: a comprehensive study in cancer cell-lines.

Genome Medicine

Alfaro, Javier A JA; Ignatchenko, Alexandr A; Ignatchenko, Vladimir V; Sinha, Ankit A; Boutros, Paul C PC; Kislinger, Thomas T

Publication Date: 2017-07-18

Variant appearance in text: p53: K24N

PubMed Link: 28716134

Variant Present in the following documents:

• 13073_2017_454_MOESM6_ESM.xlsx, sheet 1

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Residue-Specific Interactions of an Intrinsically Disordered Protein with Silica Nanoparticles and their Quantitative Prediction.

The Journal Of Physical Chemistry. C, Nanomaterials And Interfaces

Xie, Mouzhe M; Hansen, Alexandar L AL; Yuan, Jiaqi J; Brüschweiler, Rafael R

Publication Date: 2016-10-27

Variant appearance in text: p53: K24N

PubMed Link: 28337243

Variant Present in the following documents:

• Main text

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Digested disorder, Quarterly intrinsic disorder digest (October-November-December, 2013).

Intrinsically Disordered Proteins

DeForte, Shelly S; Reddy, Krishna D KD; Uversky, Vladimir N VN

Publication Date: 2015

Variant appearance in text: p53: K24N

PubMed Link: 28293487

Variant Present in the following documents:

• Main text

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Transcriptional Activation of p53 during Cold Induced Torpor in the 13-Lined Ground Squirrel Ictidomys tridecemlineatus.

Biochemistry Research International

Hefler, Joshua J; Wu, Cheng-Wei CW; Storey, Kenneth B KB

Publication Date: 2015

Variant appearance in text: p53: K24N

PubMed Link: 26843984

Variant Present in the following documents:

• Main text

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GESPA: classifying nsSNPs to predict disease association.

Bmc Bioinformatics

Khurana, Jay K JK; Reeder, Jay E JE; Shrimpton, Antony E AE; Thakar, Juilee J

Publication Date: 2015-07-25

Variant appearance in text: TP53: K24N

PubMed Link: 26206375

Variant Present in the following documents:

• 12859_2015_673_MOESM1_ESM.xls, sheet 1

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Modulation of the disordered conformational ensembles of the p53 transactivation domain by cancer-associated mutations.

Plos Computational Biology

Ganguly, Debabani D; Chen, Jianhan J

Publication Date: 2015-04

Variant appearance in text: p53: K24N

PubMed Link: 25897952

Variant Present in the following documents:

• Main text
• pcbi.1004247.pdf

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Benchmarking mutation effect prediction algorithms using functionally validated cancer-related missense mutations.

Genome Biology

Martelotto, Luciano G LG; Ng, Charlotte Ky CK; De Filippo, Maria R MR; Zhang, Yan Y; Piscuoglio, Salvatore S; Lim, Raymond S RS; Shen, Ronglai R; Norton, Larry L; Reis-Filho, Jorge S JS; Weigelt, Britta B

Publication Date: 2014-10-28

Variant appearance in text: TP53: K24N

PubMed Link: 25348012

Variant Present in the following documents:

• 13059_2014_484_MOESM2_ESM.xlsx, sheet 1

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Impact of the K24N mutation on the transactivation domain of p53 and its binding to murine double-minute clone 2.

Proteins

Zhan, Yingqian Ada YA; Wu, Hongwei H; Powell, Anne T AT; Daughdrill, Gary W GW; Ytreberg, F Marty FM

Publication Date: 2013-10

Variant appearance in text: p53: K24N

PubMed Link: 23609977

Variant Present in the following documents:

• Main text

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The (1-63) region of the p53 transactivation domain aggregates in vitro into cytotoxic amyloid assemblies.

Biophysical Journal

Rigacci, Stefania S; Bucciantini, Monica M; Relini, Annalisa A; Pesce, Alessandra A; Gliozzi, Alessandra A; Berti, Andrea A; Stefani, Massimo M

Publication Date: 2008-05-01

Variant appearance in text: p53: K24N

PubMed Link: 18199664

Variant Present in the following documents:

• Main text

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