Publications:

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Synthesis of Amino Acids Bearing Halodifluoromethyl Moieties and Their Application to p53-Derived Peptides Binding to Mdm2/Mdm4.

Drug Design, Development And Therapy

Vaas, Sebastian S; Zimmermann, Markus O MO; Klett, Theresa T; Boeckler, Frank M FM

Publication Date: 2023

Variant appearance in text: p53: Lys24Arg

PubMed Link: 37128274

Variant Present in the following documents:

• Main text
• dddt-17-1247.pdf

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Identification of a Structural Determinant for Selective Targeting of HDMX.

Structure (London, England : 1993)

Ben-Nun, Yael Y; Seo, Hyuk-Soo HS; Harvey, Edward P EP; Hauseman, Zachary J ZJ; Wales, Thomas E TE; Newman, Catherine E CE; Cathcart, Ann M AM; Engen, John R JR; Dhe-Paganon, Sirano S; Walensky, Loren D LD

Publication Date: 2020-07-07

Variant appearance in text: p53: K24R

PubMed Link: 32359398

Variant Present in the following documents:

• Main text

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Crotonylation at serine 46 impairs p53 activity.

Biochemical And Biophysical Research Communications

Liao, Peng P; Bhattarai, Nimisha N; Cao, Bo B; Zhou, Xiang X; Jung, Ji Hoon JH; Damera, Krishna K; Fuselier, Taylor T TT; Thareja, Suresh S; Wimley, William C WC; Wang, Binghe B; Zeng, Shelya X SX; Lu, Hua H

Publication Date: 2020-04-09

Variant appearance in text: p53: K24R

PubMed Link: 32035620

Variant Present in the following documents:

• Main text

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Protein lysine 43 methylation by EZH1 promotes AML1-ETO transcriptional repression in leukemia.

Nature Communications

Dou, Liping L; Yan, Fei F; Pang, Jiuxia J; Zheng, Dehua D; Li, Dandan D; Gao, Li L; Wang, Lijun L; Xu, Yihan Y; Shi, Jinlong J; Wang, Qian Q; Zhou, Lei L; Shen, Na N; Singh, Puja P; Wang, Lili L; Li, Yonghui Y; Gao, Yvchi Y; Liu, Tao T; Chen, Chongjian C; Al-Kali, Aref A; Litzow, Mark R MR; Chi, Young-In YI; Bode, Ann M AM; Liu, Chunhui C; Huang, Haojie H; Liu, Daihong D; Marcucci, Guido G; Liu, Shujun S; Yu, Li L

Publication Date: 2019-11-07

Variant appearance in text: p53: K24R

PubMed Link: 31699991

Variant Present in the following documents:

• Main text

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Unique Neoantigens Arise from Somatic Mutations in Patients with Gastrointestinal Cancers.

Cancer Discovery

Parkhurst, Maria R MR; Robbins, Paul F PF; Tran, Eric E; Prickett, Todd D TD; Gartner, Jared J JJ; Jia, Li L; Ivey, Gabriel G; Li, Yong F YF; El-Gamil, Mona M; Lalani, Almin A; Crystal, Jessica S JS; Sachs, Abraham A; Groh, Eric E; Ray, Satyajit S; Ngo, Lien T LT; Kivitz, Scott S; Pasetto, Anna A; Yossef, Rami R; Lowery, Frank J FJ; Goff, Stephanie L SL; Lo, Winifred W; Cafri, Gal G; Deniger, Drew C DC; Malekzadeh, Parisa P; Ahmadzadeh, Mojgan M; Wunderlich, John R JR; Somerville, Robert P T RPT; Rosenberg, Steven A SA

Publication Date: 2019-08

Variant appearance in text: TP53: K24R

PubMed Link: 31164343

Variant Present in the following documents:

• Main text

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appreci8: a pipeline for precise variant calling integrating 8 tools.

Bioinformatics (Oxford, England)

Sandmann, Sarah S; Karimi, Mohsen M; de Graaf, Aniek O AO; Rohde, Christian C; Göllner, Stefanie S; Varghese, Julian J; Ernsting, Jan J; Walldin, Gunilla G; van der Reijden, Bert A BA; Müller-Tidow, Carsten C; Malcovati, Luca L; Hellström-Lindberg, Eva E; Jansen, Joop H JH; Dugas, Martin M

Publication Date: 2018-12-15

Variant appearance in text: TP53: 71A>G; Lys24Arg

PubMed Link: 29945233

Variant Present in the following documents:

• bty518_supplementary_data_s2.xlsx, sheet 8

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USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells.

Nature Communications

Padmanabhan, Achuth A; Candelaria, Nicholes N; Wong, Kwong-Kwok KK; Nikolai, Bryan C BC; Lonard, David M DM; O'Malley, Bert W BW; Richards, JoAnne S JS

Publication Date: 2018-03-28

Variant appearance in text: p53: K24R

PubMed Link: 29593334

Variant Present in the following documents:

• 41467_2018_3599_MOESM1_ESM.pdf

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TRAF6 Restricts p53 Mitochondrial Translocation, Apoptosis, and Tumor Suppression.

Molecular Cell

Zhang, Xian X; Li, Chien-Feng CF; Zhang, Ling L; Wu, Ching-Yuan CY; Han, Lixia L; Jin, Guoxiang G; Rezaeian, Abdol Hossein AH; Han, Fei F; Liu, Chunfang C; Xu, Chuan C; Xu, Xiaohong X; Huang, Chih-Yang CY; Tsai, Fuu-Jen FJ; Tsai, Chang-Hai CH; Watabe, Kounosuke K; Lin, Hui-Kuan HK

Publication Date: 2016-11-17

Variant appearance in text: p53: K24R

PubMed Link: 27818144

Variant Present in the following documents:

• Main text

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iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports

Wang, Meng M; Wei, Liping L

Publication Date: 2016-08-16

Variant appearance in text: TP53: K24R

PubMed Link: 27527004

Variant Present in the following documents:

• srep31321-s5.xls, sheet 1

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Double Strain-Promoted Macrocyclization for the Rapid Selection of Cell-Active Stapled Peptides.

Angewandte Chemie (International Ed. In English)

Lau, Yu Heng YH; Wu, Yuteng Y; Rossmann, Maxim M; Tan, Ban Xiong BX; de Andrade, Peterson P; Tan, Yaw Sing YS; Verma, Chandra C; McKenzie, Grahame J GJ; Venkitaraman, Ashok R AR; Hyvönen, Marko M; Spring, David R DR

Publication Date: 2015-12-14

Variant appearance in text: p53: K24R

PubMed Link: 26768531

Variant Present in the following documents:

• Main text

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SUMOylation Confers Posttranslational Stability on NPM-ALK Oncogenic Protein.

Neoplasia (New York, N.Y.)

Vishwamitra, Deeksha D; Curry, Choladda V CV; Shi, Ping P; Alkan, Serhan S; Amin, Hesham M HM

Publication Date: 2015-09

Variant appearance in text: p53: K24R

PubMed Link: 26476082

Variant Present in the following documents:

• main.pdf

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The leukemogenicity of AML1-ETO is dependent on site-specific lysine acetylation.

Science (New York, N.Y.)

Wang, Lan L; Gural, Alexander A; Sun, Xiao-Jian XJ; Zhao, Xinyang X; Perna, Fabiana F; Huang, Gang G; Hatlen, Megan A MA; Vu, Ly L; Liu, Fan F; Xu, Haiming H; Asai, Takashi T; Xu, Hao H; Deblasio, Tony T; Menendez, Silvia S; Voza, Francesca F; Jiang, Yanwen Y; Cole, Philip A PA; Zhang, Jinsong J; Melnick, Ari A; Roeder, Robert G RG; Nimer, Stephen D SD

Publication Date: 2011-08-05

Variant appearance in text: p53: K24R

PubMed Link: 21764752

Variant Present in the following documents:

• Main text

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E3 ubiquitin ligase Hades negatively regulates the exonuclear function of p53.

Cell Death And Differentiation

Jung, J H JH; Bae, S S; Lee, J Y JY; Woo, S R SR; Cha, H J HJ; Yoon, Y Y; Suh, K-S KS; Lee, S-J SJ; Park, I-C IC; Jin, Y-W YW; Lee, K-H KH; An, S S; Lee, J H JH

Publication Date: 2011-12

Variant appearance in text: p53: K24R

PubMed Link: 21597459

Variant Present in the following documents:

• Main text

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Adenovirus E1B 55-kilodalton protein is a p53-SUMO1 E3 ligase that represses p53 and stimulates its nuclear export through interactions with promyelocytic leukemia nuclear bodies.

Journal Of Virology

Pennella, Mario A MA; Liu, Yue Y; Woo, Jennifer L JL; Kim, Chongwoo A CA; Berk, Arnold J AJ

Publication Date: 2010-12

Variant appearance in text: p53: K24R

PubMed Link: 20861261

Variant Present in the following documents:

• Main text

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Acetylation/deacetylation modulates the stability of DNA replication licensing factor Cdt1.

The Journal Of Biological Chemistry

Glozak, Michele A MA; Seto, Edward E

Publication Date: 2009-04-24

Variant appearance in text: p53: K24R

PubMed Link: 19276081

Variant Present in the following documents:

• Main text

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Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway.

Oncogene

Busso, C S CS; Iwakuma, T T; Izumi, T T

Publication Date: 2009-04-02

Variant appearance in text: p53: K24R

PubMed Link: 19219073

Variant Present in the following documents:

• Main text
• nihms85002.pdf

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Sumoylation of nucleophosmin/B23 regulates its subcellular localization, mediating cell proliferation and survival.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Liu, Xia X; Liu, Zhixue Z; Jang, Sung-Wuk SW; Ma, Zhiyong Z; Shinmura, Kazuya K; Kang, Sumin S; Dong, Shaozhong S; Chen, Jing J; Fukasawa, Kenji K; Ye, Keqiang K

Publication Date: 2007-06-05

Variant appearance in text: p53: K24R

PubMed Link: 17535915

Variant Present in the following documents:

• Main text

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Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide.

Journal Of The American Chemical Society

Bernal, Federico F; Tyler, Andrew F AF; Korsmeyer, Stanley J SJ; Walensky, Loren D LD; Verdine, Gregory L GL

Publication Date: 2007-03-07

Variant appearance in text: p53: K24R

PubMed Link: 17284038

Variant Present in the following documents:

• Main text

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