TP53 c.65T>G ;(p.L22R)

Variant ID: 17-7579848-A-C

NM_000546.5(TP53):c.65T>G;(p.L22R)

This variant was identified in 8 publications

View GRCh38 version.




Publications:


Identification of a Structural Determinant for Selective Targeting of HDMX.

Structure (London, England : 1993)
Ben-Nun, Yael Y; Seo, Hyuk-Soo HS; Harvey, Edward P EP; Hauseman, Zachary J ZJ; Wales, Thomas E TE; Newman, Catherine E CE; Cathcart, Ann M AM; Engen, John R JR; Dhe-Paganon, Sirano S; Walensky, Loren D LD
Publication Date: 2020-07-07

Variant appearance in text: p53: L22R
PubMed Link: 32359398
Variant Present in the following documents:
  • Main text
View BVdb publication page



AMLVaran: a software approach to implement variant analysis of targeted NGS sequencing data in an oncological care setting.

Bmc Medical Genomics
Wünsch, Christian C; Banck, Henrik H; Müller-Tidow, Carsten C; Dugas, Martin M
Publication Date: 2020-02-04

Variant appearance in text: TP53: 65T>G
PubMed Link: 32019565
Variant Present in the following documents:
  • 12920_2020_668_MOESM6_ESM.xls, sheet 1
View BVdb publication page



appreci8: a pipeline for precise variant calling integrating 8 tools.

Bioinformatics (Oxford, England)
Sandmann, Sarah S; Karimi, Mohsen M; de Graaf, Aniek O AO; Rohde, Christian C; Göllner, Stefanie S; Varghese, Julian J; Ernsting, Jan J; Walldin, Gunilla G; van der Reijden, Bert A BA; Müller-Tidow, Carsten C; Malcovati, Luca L; Hellström-Lindberg, Eva E; Jansen, Joop H JH; Dugas, Martin M
Publication Date: 2018-12-15

Variant appearance in text: TP53: 65T>G; Leu22Arg
PubMed Link: 29945233
Variant Present in the following documents:
  • bty518_supplementary_data_s2.xlsx, sheet 9
View BVdb publication page



The Transactivation Domains of the p53 Protein.

Cold Spring Harbor Perspectives In Medicine
Raj, Nitin N; Attardi, Laura D LD
Publication Date: 2017-01-03

Variant appearance in text: p53: L22R
PubMed Link: 27864306
Variant Present in the following documents:
  • Main text
View BVdb publication page



iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: L22R
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
View BVdb publication page



Interaction between transactivation domain of p53 and middle part of TBP-like protein (TLP) is involved in TLP-stimulated and p53-activated transcription from the p21 upstream promoter.

Plos One
Maeda, Ryo R; Suzuki, Hidefumi H; Tanaka, Yuta Y; Tamura, Taka-aki TA
Publication Date: 2014

Variant appearance in text: p53: L22R
PubMed Link: 24594805
Variant Present in the following documents:
  • Main text
  • pone.0090190.pdf
View BVdb publication page



The menin tumor suppressor protein is phosphorylated in response to DNA damage.

Plos One
Francis, Joshua J; Lin, Wenchu W; Rozenblatt-Rosen, Orit O; Meyerson, Matthew M
Publication Date: 2011-01-14

Variant appearance in text: p53: L22R
PubMed Link: 21264250
Variant Present in the following documents:
  • pone.0016119.pdf
View BVdb publication page



Identification of critical amino acid residues on human dihydrofolate reductase protein that mediate RNA recognition.

Nucleic Acids Research
Tai, Ningwen N; Ding, Yuyan Y; Schmitz, John C JC; Chu, Edward E
Publication Date: 2002-10-15

Variant appearance in text: p53: L22R
PubMed Link: 12384595
Variant Present in the following documents:
  • Main text
View BVdb publication page