TP53 c.58T>C ;(p.S20P)

Variant ID: 17-7579855-A-G

NM_000546.5(TP53):c.58T>C;(p.S20P)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


Analysis of single-nucleotide polymorphisms in genes associated with triple-negative breast cancer.

Frontiers In Genetics
G, Vigneshwaran V; Hasan, Qurratulain Annie QA; Kumar, Rahul R; Eranki, Avinash A
Publication Date: 2022

Variant appearance in text: rs876659913
PubMed Link: 36561320
Variant Present in the following documents:
  • Table2.xlsx, sheet 7
View BVdb publication page



Unique Growth Pattern Presentation of a Papillary Renal Cell Carcinoma.

Diagnostics (Basel, Switzerland)
Harich, Octavia Oana OO; Olteanu, Gheorghe-Emilian GE; Mihai, Ioana Maria IM; Benta, Marius M; Isabella, Gavriliuc Oana GO; Virgil, Paunescu P; Bojin, Florina Maria FM
Publication Date: 2022-08-06

Variant appearance in text: TP53: 58T>C; S20P
PubMed Link: 36010254
Variant Present in the following documents:
  • diagnostics-12-01904.pdf
View BVdb publication page



Scalable multiplex co-fractionation/mass spectrometry platform for accelerated protein interactome discovery.

Nature Communications
Havugimana, Pierre C PC; Goel, Raghuveera Kumar RK; Phanse, Sadhna S; Youssef, Ahmed A; Padhorny, Dzmitry D; Kotelnikov, Sergei S; Kozakov, Dima D; Emili, Andrew A
Publication Date: 2022-07-13

Variant appearance in text: TP53: 58T>C; Ser20Pro
PubMed Link: 35831314
Variant Present in the following documents:
  • 41467_2022_31809_MOESM8_ESM.xlsx, sheet 3
View BVdb publication page



A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports
Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM
Publication Date: 2021-07-12

Variant appearance in text: TP53: 58T>C; Ser20Pro
PubMed Link: 34253785
Variant Present in the following documents:
  • 41598_2021_93715_MOESM2_ESM.xlsx, sheet 8
View BVdb publication page



Plasma ctDNA is a tumor tissue surrogate and enables clinical-genomic stratification of metastatic bladder cancer.

Nature Communications
Vandekerkhove, Gillian G; Lavoie, Jean-Michel JM; Annala, Matti M; Murtha, Andrew J AJ; Sundahl, Nora N; Walz, Simon S; Sano, Takeshi T; Taavitsainen, Sinja S; Ritch, Elie E; Fazli, Ladan L; Hurtado-Coll, Antonio A; Wang, Gang G; Nykter, Matti M; Black, Peter C PC; Todenhöfer, Tilman T; Ost, Piet P; Gibb, Ewan A EA; Chi, Kim N KN; Eigl, Bernhard J BJ; Wyatt, Alexander W AW
Publication Date: 2021-01-08

Variant appearance in text: TP53: S20P
PubMed Link: 33420073
Variant Present in the following documents:
  • 41467_2020_20493_MOESM3_ESM.xlsx, sheet 7
View BVdb publication page



PhosphoEffect: Prioritizing Variants On or Adjacent to Phosphorylation Sites through Their Effect on Kinase Recognition Motifs.

Iscience
Cole, Stephen S; Prabakaran, Sudhakaran S
Publication Date: 2020-08-21

Variant appearance in text: p53: S20P
PubMed Link: 32712465
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



From uncertainty to pathogenicity: clinical and functional interrogation of a rare TP53 in-frame deletion.

Cold Spring Harbor Molecular Case Studies
Quinn, Emily A EA; Maciaszek, Jamie L JL; Pinto, Emilia M EM; Phillips, Aaron H AH; Berdy, David D; Khandwala, Mohammad M; Upadhyaya, Santhosh A SA; Zambetti, Gerard P GP; Kriwacki, Richard W RW; Ellison, David W DW; Nichols, Kim E KE; Kesserwan, Chimene C
Publication Date: 2019-08

Variant appearance in text: TP53: 58T>C; Ser20Pro
PubMed Link: 30886117
Variant Present in the following documents:
  • supp_mcs.a003921_Supplemental_Table_1a.xlsx, sheet 1
View BVdb publication page



appreci8: a pipeline for precise variant calling integrating 8 tools.

Bioinformatics (Oxford, England)
Sandmann, Sarah S; Karimi, Mohsen M; de Graaf, Aniek O AO; Rohde, Christian C; Göllner, Stefanie S; Varghese, Julian J; Ernsting, Jan J; Walldin, Gunilla G; van der Reijden, Bert A BA; Müller-Tidow, Carsten C; Malcovati, Luca L; Hellström-Lindberg, Eva E; Jansen, Joop H JH; Dugas, Martin M
Publication Date: 2018-12-15

Variant appearance in text: TP53: 58T>C; Ser20Pro
PubMed Link: 29945233
Variant Present in the following documents:
  • bty518_supplementary_data_s2.xlsx, sheet 8
View BVdb publication page



iFish: predicting the pathogenicity of human nonsynonymous variants using gene-specific/family-specific attributes and classifiers.

Scientific Reports
Wang, Meng M; Wei, Liping L
Publication Date: 2016-08-16

Variant appearance in text: TP53: S20P
PubMed Link: 27527004
Variant Present in the following documents:
  • srep31321-s5.xls, sheet 1
View BVdb publication page



B'-protein phosphatase 2A is a functional binding partner of delta-retroviral integrase.

Nucleic Acids Research
Maertens, Goedele N GN
Publication Date: 2016-01-08

Variant appearance in text: p53: S20P
PubMed Link: 26657642
Variant Present in the following documents:
  • Main text
  • gkv1347.pdf
View BVdb publication page



Negative Regulation of p21Waf1/Cip1 by Human INO80 Chromatin Remodeling Complex Is Implicated in Cell Cycle Phase G2/M Arrest and Abnormal Chromosome Stability.

Plos One
Cao, Lingling L; Ding, Jian J; Dong, Liguo L; Zhao, Jiayao J; Su, Jiaming J; Wang, Lingyao L; Sui, Yi Y; Zhao, Tong T; Wang, Fei F; Jin, Jingji J; Cai, Yong Y
Publication Date: 2015

Variant appearance in text: p53: S20p
PubMed Link: 26340092
Variant Present in the following documents:
  • Main text
  • pone.0137411.pdf
View BVdb publication page



Interaction between transactivation domain of p53 and middle part of TBP-like protein (TLP) is involved in TLP-stimulated and p53-activated transcription from the p21 upstream promoter.

Plos One
Maeda, Ryo R; Suzuki, Hidefumi H; Tanaka, Yuta Y; Tamura, Taka-aki TA
Publication Date: 2014

Variant appearance in text: p53: S20P
PubMed Link: 24594805
Variant Present in the following documents:
  • Main text
  • pone.0090190.pdf
View BVdb publication page



Radiation-induced phosphorylation of Chk1 at S345 is associated with p53-dependent cell cycle arrest pathways.

Neoplasia (New York, N.Y.)
Tian, Hui H; Faje, Alexander T AT; Lee, Siu Lan SL; Jorgensen, Timothy J TJ
Publication Date: 2002

Variant appearance in text: p53: S20p
PubMed Link: 11896572
Variant Present in the following documents:
  • Main text
View BVdb publication page



Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53.

Genes & Development
Chehab, N H NH; Malikzay, A A; Appel, M M; Halazonetis, T D TD
Publication Date: 2000-02-01

Variant appearance in text: p53: S20p
PubMed Link: 10673500
Variant Present in the following documents:
  • Main text
View BVdb publication page