Beneficial effects of mifepristone treatment in breast cancer patients selected by the progesterone receptor isoform ratio: Results from the MIPRA trial.
Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Elía, Andrés A; Saldain, Leo L; Vanzulli, Silvia I SI; Helguero, Luisa A LA; Lamb, Caroline A CA; Fabris, Victoria V; Pataccini, Gabriela G; Martínez-Vazquez, Paula P; Burruchaga, Javier J; Caillet-Bois, Ines I; Spengler, Eunice E; Acosta Haab, Gabriela G; Liguori, Marcos M; Castets, Alejandra A; Lovisi, Silvia S; Abascal, María F MF; Novaro, Virginia V; Sánchez, Jana J; Muñoz, Javier J; Belizán, Jose M JM; Abba, Martín C MC; Gass, Hugo H; Rojas, Paola P; Lanari, Claudia C
Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control.
Diabetologia
Tremblay, Johanne J; Haloui, Mounsif M; Attaoua, Redha R; Tahir, Ramzan R; Hishmih, Camil C; Harvey, François F; Marois-Blanchet, François-Christophe FC; Long, Carole C; Simon, Paul P; Santucci, Lara L; Hizel, Candan C; Chalmers, John J; Marre, Michel M; Harrap, Stephen S; Cífková, Renata R; Krajčoviechová, Alena A; Matthews, David R DR; Williams, Bryan B; Poulter, Neil N; Zoungas, Sophia S; Colagiuri, Stephen S; Mancia, Giuseppe G; Grobbee, Diederick E DE; Rodgers, Anthony A; Liu, Liusheng L; Agbessi, Mawussé M; Bruat, Vanessa V; Favé, Marie-Julie MJ; Harwood, Michelle P MP; Awadalla, Philip P; Woodward, Mark M; Hussin, Julie G JG; Hamet, Pavel P
Exome-Wide Association Study Identifies FN3KRP and PGP as New Candidate Longevity Genes.
The Journals Of Gerontology. Series A, Biological Sciences And Medical Sciences
Torres, Guillermo G GG; Nygaard, Marianne M; Caliebe, Amke A; Blanché, Hélène H; Chantalat, Sophie S; Galan, Pilar P; Lieb, Wolfgang W; Christiansen, Lene L; Deleuze, Jean-François JF; Christensen, Kaare K; Strauch, Konstantin K; Müller-Nurasyid, Martina M; Peters, Annette A; Nöthen, Markus M MM; Hoffmann, Per P; Flachsbart, Friederike F; Schreiber, Stefan S; Ellinghaus, David D; Franke, Andre A; Dose, Janina J; Nebel, Almut A
FN3K expression in COPD: a potential comorbidity factor for cardiovascular disease.
Bmj Open Respiratory Research
Alderawi, Amr A; Caramori, Gaetano G; Baker, Emma H EH; Hitchings, Andrew William AW; Rahman, Irfan I; Rossios, Christos C; Adcock, Ian I; Cassolari, Paolo P; Papi, Alberto A; Ortega, Victor E VE; Curtis, Jeffrey L JL; Dunmore, Simon S; Kirkham, Paul P
Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program.
American Journal Of Human Genetics
Sarnowski, Chloé C; Leong, Aaron A; Raffield, Laura M LM; Wu, Peitao P; de Vries, Paul S PS; DiCorpo, Daniel D; Guo, Xiuqing X; Xu, Huichun H; Liu, Yongmei Y; Zheng, Xiuwen X; Hu, Yao Y; Brody, Jennifer A JA; Goodarzi, Mark O MO; Hidalgo, Bertha A BA; Highland, Heather M HM; Jain, Deepti D; Liu, Ching-Ti CT; Naik, Rakhi P RP; O'Connell, Jeffrey R JR; Perry, James A JA; Porneala, Bianca C BC; Selvin, Elizabeth E; Wessel, Jennifer J; Psaty, Bruce M BM; Curran, Joanne E JE; Peralta, Juan M JM; Blangero, John J; Kooperberg, Charles C; Mathias, Rasika R; Johnson, Andrew D AD; Reiner, Alexander P AP; Mitchell, Braxton D BD; Cupples, L Adrienne LA; Vasan, Ramachandran S RS; Correa, Adolfo A; Morrison, Alanna C AC; Boerwinkle, Eric E; Rotter, Jerome I JI; Rich, Stephen S SS; Manning, Alisa K AK; Dupuis, Josée J; Meigs, James B JB; , ; , ; , ; ,
Mendelian Randomization Analysis Support Causal Associations of HbA1c with Circulating Triglyceride, Total and Low-density Lipoprotein Cholesterol in a Chinese Population.
Scientific Reports
Jia, Xu X; Hou, Yanan Y; Xu, Min M; Zhao, Zhiyun Z; Xuan, Liping L; Wang, Tiange T; Li, Mian M; Xu, Yu Y; Lu, Jieli J; Bi, Yufang Y; Wang, Weiqing W; Chen, Yuhong Y
Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study.
Diabetes
Loomis, Stephanie J SJ; Li, Man M; Maruthur, Nisa M NM; Baldridge, Abigail S AS; North, Kari E KE; Mei, Hao H; Morrison, Alanna A; Carson, April P AP; Pankow, James S JS; Boerwinkle, Eric E; Scharpf, Robert R; Rasmussen-Torvik, Laura J LJ; Coresh, Josef J; Duggal, Priya P; Köttgen, Anna A; Selvin, Elizabeth E
Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population.
European Journal Of Human Genetics : Ejhg
Appel, Emil V R EVR; Moltke, Ida I; Jørgensen, Marit E ME; Bjerregaard, Peter P; Linneberg, Allan A; Pedersen, Oluf O; Albrechtsen, Anders A; Hansen, Torben T; Grarup, Niels N
Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.
Plos Medicine
Wheeler, Eleanor E; Leong, Aaron A; Liu, Ching-Ti CT; Hivert, Marie-France MF; Strawbridge, Rona J RJ; Podmore, Clara C; Li, Man M; Yao, Jie J; Sim, Xueling X; Hong, Jaeyoung J; Chu, Audrey Y AY; Zhang, Weihua W; Wang, Xu X; Chen, Peng P; Maruthur, Nisa M NM; Porneala, Bianca C BC; Sharp, Stephen J SJ; Jia, Yucheng Y; Kabagambe, Edmond K EK; Chang, Li-Ching LC; Chen, Wei-Min WM; Elks, Cathy E CE; Evans, Daniel S DS; Fan, Qiao Q; Giulianini, Franco F; Go, Min Jin MJ; Hottenga, Jouke-Jan JJ; Hu, Yao Y; Jackson, Anne U AU; Kanoni, Stavroula S; Kim, Young Jin YJ; Kleber, Marcus E ME; Ladenvall, Claes C; Lecoeur, Cecile C; Lim, Sing-Hui SH; Lu, Yingchang Y; Mahajan, Anubha A; Marzi, Carola C; Nalls, Mike A MA; Navarro, Pau P; Nolte, Ilja M IM; Rose, Lynda M LM; Rybin, Denis V DV; Sanna, Serena S; Shi, Yuan Y; Stram, Daniel O DO; Takeuchi, Fumihiko F; Tan, Shu Pei SP; van der Most, Peter J PJ; Van Vliet-Ostaptchouk, Jana V JV; Wong, Andrew A; Yengo, Loic L; Zhao, Wanting W; Goel, Anuj A; Martinez Larrad, Maria Teresa MT; Radke, Dörte D; Salo, Perttu P; Tanaka, Toshiko T; van Iperen, Erik P A EPA; Abecasis, Goncalo G; Afaq, Saima S; Alizadeh, Behrooz Z BZ; Bertoni, Alain G AG; Bonnefond, Amelie A; Böttcher, Yvonne Y; Bottinger, Erwin P EP; Campbell, Harry H; Carlson, Olga D OD; Chen, Chien-Hsiun CH; Cho, Yoon Shin YS; Garvey, W Timothy WT; Gieger, Christian C; Goodarzi, Mark O MO; Grallert, Harald H; Hamsten, Anders A; Hartman, Catharina A CA; Herder, Christian C; Hsiung, Chao Agnes CA; Huang, Jie J; Igase, Michiya M; Isono, Masato M; Katsuya, Tomohiro T; Khor, Chiea-Chuen CC; Kiess, Wieland W; Kohara, Katsuhiko K; Kovacs, Peter P; Lee, Juyoung J; Lee, Wen-Jane WJ; Lehne, Benjamin B; Li, Huaixing H; Liu, Jianjun J; Lobbens, Stephane S; Luan, Jian'an J; Lyssenko, Valeriya V; Meitinger, Thomas T; Miki, Tetsuro T; Miljkovic, Iva I; Moon, Sanghoon S; Mulas, Antonella A; Müller, Gabriele G; Müller-Nurasyid, Martina M; Nagaraja, Ramaiah R; Nauck, Matthias M; Pankow, James S JS; Polasek, Ozren O; Prokopenko, Inga I; Ramos, Paula S PS; Rasmussen-Torvik, Laura L; Rathmann, Wolfgang W; Rich, Stephen S SS; Robertson, Neil R NR; Roden, Michael M; Roussel, Ronan R; Rudan, Igor I; Scott, Robert A RA; Scott, William R WR; Sennblad, Bengt B; Siscovick, David S DS; Strauch, Konstantin K; Sun, Liang L; Swertz, Morris M; Tajuddin, Salman M SM; Taylor, Kent D KD; Teo, Yik-Ying YY; Tham, Yih Chung YC; Tönjes, Anke A; Wareham, Nicholas J NJ; Willemsen, Gonneke G; Wilsgaard, Tom T; Hingorani, Aroon D AD; , ; , ; , ; Egan, Josephine J; Ferrucci, Luigi L; Hovingh, G Kees GK; Jula, Antti A; Kivimaki, Mika M; Kumari, Meena M; Njølstad, Inger I; Palmer, Colin N A CNA; Serrano Ríos, Manuel M; Stumvoll, Michael M; Watkins, Hugh H; Aung, Tin T; Blüher, Matthias M; Boehnke, Michael M; Boomsma, Dorret I DI; Bornstein, Stefan R SR; Chambers, John C JC; Chasman, Daniel I DI; Chen, Yii-Der Ida YI; Chen, Yduan-Tsong YT; Cheng, Ching-Yu CY; Cucca, Francesco F; de Geus, Eco J C EJC; Deloukas, Panos P; Evans, Michele K MK; Fornage, Myriam M; Friedlander, Yechiel Y; Froguel, Philippe P; Groop, Leif L; Gross, Myron D MD; Harris, Tamara B TB; Hayward, Caroline C; Heng, Chew-Kiat CK; Ingelsson, Erik E; Kato, Norihiro N; Kim, Bong-Jo BJ; Koh, Woon-Puay WP; Kooner, Jaspal S JS; Körner, Antje A; Kuh, Diana D; Kuusisto, Johanna J; Laakso, Markku M; Lin, Xu X; Liu, Yongmei Y; Loos, Ruth J F RJF; Magnusson, Patrik K E PKE; März, Winfried W; McCarthy, Mark I MI; Oldehinkel, Albertine J AJ; Ong, Ken K KK; Pedersen, Nancy L NL; Pereira, Mark A MA; Peters, Annette A; Ridker, Paul M PM; Sabanayagam, Charumathi C; Sale, Michele M; Saleheen, Danish D; Saltevo, Juha J; Schwarz, Peter Eh PE; Sheu, Wayne H H WHH; Snieder, Harold H; Spector, Timothy D TD; Tabara, Yasuharu Y; Tuomilehto, Jaakko J; van Dam, Rob M RM; Wilson, James G JG; Wilson, James F JF; Wolffenbuttel, Bruce H R BHR; Wong, Tien Yin TY; Wu, Jer-Yuarn JY; Yuan, Jian-Min JM; Zonderman, Alan B AB; Soranzo, Nicole N; Guo, Xiuqing X; Roberts, David J DJ; Florez, Jose C JC; Sladek, Robert R; Dupuis, Josée J; Morris, Andrew P AP; Tai, E-Shyong ES; Selvin, Elizabeth E; Rotter, Jerome I JI; Langenberg, Claudia C; Barroso, Inês I; Meigs, James B JB
A Mendelian randomization study of the effect of type-2 diabetes on coronary heart disease.
Nature Communications
Ahmad, Omar S OS; Morris, John A JA; Mujammami, Muhammad M; Forgetta, Vincenzo V; Leong, Aaron A; Li, Rui R; Turgeon, Maxime M; Greenwood, Celia M T CM; Thanassoulis, George G; Meigs, James B JB; Sladek, Robert R; Richards, J Brent JB
Mapping eQTLs in the Norfolk Island genetic isolate identifies candidate genes for CVD risk traits.
American Journal Of Human Genetics
Benton, Miles C MC; Lea, Rod A RA; Macartney-Coxson, Donia D; Carless, Melanie A MA; Göring, Harald H HH; Bellis, Claire C; Hanna, Michelle M; Eccles, David D; Chambers, Geoffrey K GK; Curran, Joanne E JE; Harper, Jacquie L JL; Blangero, John J; Griffiths, Lyn R LR
A study assessing the association of glycated hemoglobin A1C (HbA1C) associated variants with HbA1C, chronic kidney disease and diabetic retinopathy in populations of Asian ancestry.
Plos One
Chen, Peng P; Ong, Rick Twee-Hee RT; Tay, Wan-Ting WT; Sim, Xueling X; Ali, Mohammad M; Xu, Haiyan H; Suo, Chen C; Liu, Jianjun J; Chia, Kee-Seng KS; Vithana, Eranga E; Young, Terri L TL; Aung, Tin T; Lim, Wei-Yen WY; Khor, Chiea-Chuen CC; Cheng, Ching-Yu CY; Wong, Tien-Yin TY; Teo, Yik-Ying YY; Tai, E-Shyong ES
Association of ketone body levels with hyperglycemia and type 2 diabetes in 9,398 Finnish men.
Diabetes
Mahendran, Yuvaraj Y; Vangipurapu, Jagadish J; Cederberg, Henna H; Stancáková, Alena A; Pihlajamäki, Jussi J; Soininen, Pasi P; Kangas, Antti J AJ; Paananen, Jussi J; Civelek, Mete M; Saleem, Niyas K NK; Pajukanta, Päivi P; Lusis, Aldons J AJ; Bonnycastle, Lori L LL; Morken, Mario A MA; Collins, Francis S FS; Mohlke, Karen L KL; Boehnke, Michael M; Ala-Korpela, Mika M; Kuusisto, Johanna J; Laakso, Markku M
Race-ethnic differences in the association of genetic loci with HbA1c levels and mortality in U.S. adults: the third National Health and Nutrition Examination Survey (NHANES III).
Bmc Medical Genetics
Grimsby, Jonna L JL; Porneala, Bianca C BC; Vassy, Jason L JL; Yang, Quanhe Q; Florez, José C JC; Dupuis, Josée J; Liu, Tiebin T; Yesupriya, Ajay A; Chang, Man-Huei MH; Ned, Renee M RM; Dowling, Nicole F NF; Khoury, Muin J MJ; Meigs, James B JB; ,
Genome-wide analysis of genetic susceptibility to language impairment in an isolated Chilean population.
European Journal Of Human Genetics : Ejhg
Villanueva, Pia P; Newbury, Dianne F DF; Jara, Lilian L; De Barbieri, Zulema Z; Mirza, Ghazala G; Palomino, Hernán M HM; Fernández, María Angélica MA; Cazier, Jean-Baptiste JB; Monaco, Anthony P AP; Palomino, Hernán H
Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways.
Diabetes
Soranzo, Nicole N; Sanna, Serena S; Wheeler, Eleanor E; Gieger, Christian C; Radke, Dörte D; Dupuis, Josée J; Bouatia-Naji, Nabila N; Langenberg, Claudia C; Prokopenko, Inga I; Stolerman, Elliot E; Sandhu, Manjinder S MS; Heeney, Matthew M MM; Devaney, Joseph M JM; Reilly, Muredach P MP; Ricketts, Sally L SL; Stewart, Alexandre F R AF; Voight, Benjamin F BF; Willenborg, Christina C; Wright, Benjamin B; Altshuler, David D; Arking, Dan D; Balkau, Beverley B; Barnes, Daniel D; Boerwinkle, Eric E; Böhm, Bernhard B; Bonnefond, Amélie A; Bonnycastle, Lori L LL; Boomsma, Dorret I DI; Bornstein, Stefan R SR; Böttcher, Yvonne Y; Bumpstead, Suzannah S; Burnett-Miller, Mary Susan MS; Campbell, Harry H; Cao, Antonio A; Chambers, John J; Clark, Robert R; Collins, Francis S FS; Coresh, Josef J; de Geus, Eco J C EJ; Dei, Mariano M; Deloukas, Panos P; Döring, Angela A; Egan, Josephine M JM; Elosua, Roberto R; Ferrucci, Luigi L; Forouhi, Nita N; Fox, Caroline S CS; Franklin, Christopher C; Franzosi, Maria Grazia MG; Gallina, Sophie S; Goel, Anuj A; Graessler, Jürgen J; Grallert, Harald H; Greinacher, Andreas A; Hadley, David D; Hall, Alistair A; Hamsten, Anders A; Hayward, Caroline C; Heath, Simon S; Herder, Christian C; Homuth, Georg G; Hottenga, Jouke-Jan JJ; Hunter-Merrill, Rachel R; Illig, Thomas T; Jackson, Anne U AU; Jula, Antti A; Kleber, Marcus M; Knouff, Christopher W CW; Kong, Augustine A; Kooner, Jaspal J; Köttgen, Anna A; Kovacs, Peter P; Krohn, Knut K; Kühnel, Brigitte B; Kuusisto, Johanna J; Laakso, Markku M; Lathrop, Mark M; Lecoeur, Cécile C; Li, Man M; Li, Mingyao M; Loos, Ruth J F RJ; Luan, Jian'an J; Lyssenko, Valeriya V; Mägi, Reedik R; Magnusson, Patrik K E PK; Mälarstig, Anders A; Mangino, Massimo M; Martínez-Larrad, María Teresa MT; März, Winfried W; McArdle, Wendy L WL; McPherson, Ruth R; Meisinger, Christa C; Meitinger, Thomas T; Melander, Olle O; Mohlke, Karen L KL; Mooser, Vincent E VE; Morken, Mario A MA; Narisu, Narisu N; Nathan, David M DM; Nauck, Matthias M; O'Donnell, Chris C; Oexle, Konrad K; Olla, Nazario N; Pankow, James S JS; Payne, Felicity F; Peden, John F JF; Pedersen, Nancy L NL; Peltonen, Leena L; Perola, Markus M; Polasek, Ozren O; Porcu, Eleonora E; Rader, Daniel J DJ; Rathmann, Wolfgang W; Ripatti, Samuli S; Rocheleau, Ghislain G; Roden, Michael M; Rudan, Igor I; Salomaa, Veikko V; Saxena, Richa R; Schlessinger, David D; Schunkert, Heribert H; Schwarz, Peter P; Seedorf, Udo U; Selvin, Elizabeth E; Serrano-Ríos, Manuel M; Shrader, Peter P; Silveira, Angela A; Siscovick, David D; Song, Kjioung K; Spector, Timothy D TD; Stefansson, Kari K; Steinthorsdottir, Valgerdur V; Strachan, David P DP; Strawbridge, Rona R; Stumvoll, Michael M; Surakka, Ida I; Swift, Amy J AJ; Tanaka, Toshiko T; Teumer, Alexander A; Thorleifsson, Gudmar G; Thorsteinsdottir, Unnur U; Tönjes, Anke A; Usala, Gianluca G; Vitart, Veronique V; Völzke, Henry H; Wallaschofski, Henri H; Waterworth, Dawn M DM; Watkins, Hugh H; Wichmann, H-Erich HE; Wild, Sarah H SH; Willemsen, Gonneke G; Williams, Gordon H GH; Wilson, James F JF; Winkelmann, Juliane J; Wright, Alan F AF; , ; Zabena, Carina C; Zhao, Jing Hua JH; Epstein, Stephen E SE; Erdmann, Jeanette J; Hakonarson, Hakon H HH; Kathiresan, Sekar S; Khaw, Kay-Tee KT; Roberts, Robert R; Samani, Nilesh J NJ; Fleming, Mark D MD; Sladek, Robert R; Abecasis, Gonçalo G; Boehnke, Michael M; Froguel, Philippe P; Groop, Leif L; McCarthy, Mark I MI; Kao, W H Linda WH; Florez, Jose C JC; Uda, Manuela M; Wareham, Nicholas J NJ; Barroso, Inês I; Meigs, James B JB