A Genome-Wide Association Study Reveals a BDNF-Centered Molecular Network Associated with Alcohol Dependence and Related Clinical Measures.
Biomedicines
Levchenko, Anastasia A; Malov, Sergey S; Antonik, Alexey A; Protsvetkina, Anastasia A; Rybakova, Kseniya V KV; Kanapin, Alexander A; Yakovlev, Alexey N AN; Nenasteva, Anna Y AY; Nikolishin, Anton E AE; Cherkasov, Nikolay N; Chuprova, Natalia A NA; Blagonravova, Anna S AS; Sergeeva, Angelica V AV; Zhilyaeva, Tatyana V TV; Denisenko, Maria K MK; Gainetdinov, Raul R RR; Kibitov, Alexander O AO; Krupitsky, Evgeny M EM
TF and TCF4 gene polymorphisms are linked to autism spectrum disorder: a case-control study.
The Journal Of International Medical Research
Azmerin, Maria M; Hussain, Md Saddam MS; Aziz, Md Abdul MA; Barek, Md Abdul MA; Begum, Mobashera M; Sen, Niloy N; Rahman, Md Abdur MA; Shahriar, Mohammad M; Baeesa, Saleh Salem SS; Ashraf, Ghulam Md GM; Islam, Mohammad Safiqul MS
Neural mapping of prepulse-induced startle reflex modulation as indices of sensory information processing in healthy and clinical populations: A systematic review.
Human Brain Mapping
Naysmith, Laura F LF; Kumari, Veena V; Williams, Steven C R SCR
Neural mapping of prepulse-induced startle reflex modulation as indices of sensory information processing in healthy and clinical populations: A systematic review.
Human Brain Mapping
Naysmith, Laura F LF; Kumari, Veena V; Williams, Steven C R SCR
Population-Wide Genetic Risk Prediction of Complex Diseases: A Pilot Feasibility Study in Macau Population for Precision Public Healthcare Planning.
Scientific Reports
Tsui, Nancy B Y NBY; Cheng, Gregory G; Chung, Teresa T; Lam, Christopher W K CWK; Yee, Anita A; Chung, Peter K C PKC; Kwan, Tsz-Ki TK; Ko, Elaine E; He, Daihai D; Wong, Wing-Tak WT; Lau, Johnson Y N JYN; Lau, Lok Ting LT; Fok, Manson M
The schizophrenia- and autism-associated gene, transcription factor 4 regulates the columnar distribution of layer 2/3 prefrontal pyramidal neurons in an activity-dependent manner.
Molecular Psychiatry
Page, S C SC; Hamersky, G R GR; Gallo, R A RA; Rannals, M D MD; Calcaterra, N E NE; Campbell, M N MN; Mayfield, B B; Briley, A A; Phan, B N BN; Jaffe, A E AE; Maher, B J BJ
Tcf4 Regulates Synaptic Plasticity, DNA Methylation, and Memory Function.
Cell Reports
Kennedy, Andrew J AJ; Rahn, Elizabeth J EJ; Paulukaitis, Brynna S BS; Savell, Katherine E KE; Kordasiewicz, Holly B HB; Wang, Jing J; Lewis, John W JW; Posey, Jessica J; Strange, Sarah K SK; Guzman-Karlsson, Mikael C MC; Phillips, Scott E SE; Decker, Kyle K; Motley, S Timothy ST; Swayze, Eric E EE; Ecker, David J DJ; Michael, Todd P TP; Day, Jeremy J JJ; Sweatt, J David JD
No effect of schizophrenia risk genes MIR137, TCF4, and ZNF804A on macroscopic brain structure.
Schizophrenia Research
Cousijn, Helena H; Eissing, Marc M; Fernández, Guillén G; Fisher, Simon E SE; Franke, Barbara B; Zwiers, Marcel M; Harrison, Paul J PJ; Arias-Vásquez, Alejandro A
Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence?
Plos One
Sieradzka, Dominika D; Power, Robert A RA; Freeman, Daniel D; Cardno, Alastair G AG; McGuire, Philip P; Plomin, Robert R; Meaburn, Emma L EL; Dudbridge, Frank F; Ronald, Angelica A
Neurophysiologic effect of GWAS derived schizophrenia and bipolar risk variants.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Hall, Mei-Hua MH; Levy, Deborah L DL; Salisbury, Dean F DF; Haddad, Steve S; Gallagher, Patience P; Lohan, Mary M; Cohen, Bruce B; Ongür, Dost D; Smoller, Jordan W JW
A population-based study of genetic variation and psychotic experiences in adolescents.
Schizophrenia Bulletin
Zammit, Stanley S; Hamshere, Marian M; Dwyer, Sarah S; Georgiva, Lyudmila L; Timpson, Nic N; Moskvina, Valentina V; Richards, Alexander A; Evans, David M DM; Lewis, Glyn G; Jones, Peter P; Owen, Michael J MJ; O'Donovan, Michael C MC
A survey of rare coding variants in candidate genes in schizophrenia by deep sequencing.
Molecular Psychiatry
Hu, X X; Zhang, B B; Liu, W W; Paciga, S S; He, W W; Lanz, T A TA; Kleiman, R R; Dougherty, B B; Hall, S K SK; McIntosh, A M AM; Lawrie, S M SM; Power, A A; John, S L SL; Blackwood, D D; St Clair, D D; Brandon, N J NJ
Knockdown of human TCF4 affects multiple signaling pathways involved in cell survival, epithelial to mesenchymal transition and neuronal differentiation.
Plos One
Forrest, Marc P MP; Waite, Adrian J AJ; Martin-Rendon, Enca E; Blake, Derek J DJ
TCF4 sequence variants and mRNA levels are associated with neurodevelopmental characteristics in psychotic disorders.
Translational Psychiatry
Wirgenes, K V KV; Sønderby, I E IE; Haukvik, U K UK; Mattingsdal, M M; Tesli, M M; Athanasiu, L L; Sundet, K K; Røssberg, J I JI; Dale, A M AM; Brown, A A AA; Agartz, I I; Melle, I I; Djurovic, S S; Andreassen, O A OA
Evidence for the involvement of ZNF804A in cognitive processes of relevance to reading and spelling.
Translational Psychiatry
Becker, J J; Czamara, D D; Hoffmann, P P; Landerl, K K; Blomert, L L; Brandeis, D D; Vaessen, A A; Maurer, U U; Moll, K K; Ludwig, K U KU; Müller-Myhsok, B B; Nöthen, M M MM; Schulte-Körne, G G; Schumacher, J J
Schizophrenia risk polymorphisms in the TCF4 gene interact with smoking in the modulation of auditory sensory gating.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Quednow, Boris B BB; Brinkmeyer, Jürgen J; Mobascher, Arian A; Nothnagel, Michael M; Musso, Francesco F; Gründer, Gerhard G; Savary, Noah N; Petrovsky, Nadine N; Frommann, Ingo I; Lennertz, Leonhard L; Spreckelmeyer, Katja N KN; Wienker, Thomas F TF; Dahmen, Norbert N; Thuerauf, Norbert N; Clepce, Marion M; Kiefer, Falk F; Majic, Tomislav T; Mössner, Rainald R; Maier, Wolfgang W; Gallinat, Jürgen J; Diaz-Lacava, Amalia A; Toliat, Mohammad R MR; Thiele, Holger H; Nürnberg, Peter P; Wagner, Michael M; Winterer, Georg G
Genome-wide association study of Alzheimer's disease with psychotic symptoms.
Molecular Psychiatry
Hollingworth, P P; Sweet, R R; Sims, R R; Harold, D D; Russo, G G; Abraham, R R; Stretton, A A; Jones, N N; Gerrish, A A; Chapman, J J; Ivanov, D D; Moskvina, V V; Lovestone, S S; Priotsi, P P; Lupton, M M; Brayne, C C; Gill, M M; Lawlor, B B; Lynch, A A; Craig, D D; McGuinness, B B; Johnston, J J; Holmes, C C; Livingston, G G; Bass, N J NJ; Gurling, H H; McQuillin, A A; , ; , ; Holmans, P P; Jones, L L; Devlin, B B; Klei, L L; Barmada, M M MM; Demirci, F Y FY; DeKosky, S T ST; Lopez, O L OL; Passmore, P P; Owen, M J MJ; O'Donovan, M C MC; Mayeux, R R; Kamboh, M I MI; Williams, J J
Association between TCF4 and schizophrenia does not exert its effect by common nonsynonymous variation or by influencing cis-acting regulation of mRNA expression in adult human brain.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Williams, Hywel J HJ; Moskvina, Valentina V; Smith, Rhodri L RL; Dwyer, Sarah S; Russo, Giancarlo G; Owen, Michael J MJ; O'Donovan, Michael C MC
Common variants at VRK2 and TCF4 conferring risk of schizophrenia.
Human Molecular Genetics
Steinberg, Stacy S; de Jong, Simone S; , ; Andreassen, Ole A OA; Werge, Thomas T; Børglum, Anders D AD; Mors, Ole O; Mortensen, Preben B PB; Gustafsson, Omar O; Costas, Javier J; Pietiläinen, Olli P H OP; Demontis, Ditte D; Papiol, Sergi S; Huttenlocher, Johanna J; Mattheisen, Manuel M; Breuer, René R; Vassos, Evangelos E; Giegling, Ina I; Fraser, Gillian G; Walker, Nicholas N; Tuulio-Henriksson, Annamari A; Suvisaari, Jaana J; Lönnqvist, Jouko J; Paunio, Tiina T; Agartz, Ingrid I; Melle, Ingrid I; Djurovic, Srdjan S; Strengman, Eric E; , ; Jürgens, Gesche G; Glenthøj, Birte B; Terenius, Lars L; Hougaard, David M DM; Ørntoft, Torben T; Wiuf, Carsten C; Didriksen, Michael M; Hollegaard, Mads V MV; Nordentoft, Merete M; van Winkel, Ruud R; Kenis, Gunter G; Abramova, Lilia L; Kaleda, Vasily V; Arrojo, Manuel M; Sanjuán, Julio J; Arango, Celso C; Sperling, Swetlana S; Rossner, Moritz M; Ribolsi, Michele M; Magni, Valentina V; Siracusano, Alberto A; Christiansen, Claus C; Kiemeney, Lambertus A LA; Veldink, Jan J; van den Berg, Leonard L; Ingason, Andres A; Muglia, Pierandrea P; Murray, Robin R; Nöthen, Markus M MM; Sigurdsson, Engilbert E; Petursson, Hannes H; Thorsteinsdottir, Unnur U; Kong, Augustine A; Rubino, I Alex IA; De Hert, Marc M; Réthelyi, János M JM; Bitter, István I; Jönsson, Erik G EG; Golimbet, Vera V; Carracedo, Angel A; Ehrenreich, Hannelore H; Craddock, Nick N; Owen, Michael J MJ; O'Donovan, Michael C MC; , ; Ruggeri, Mirella M; Tosato, Sarah S; Peltonen, Leena L; Ophoff, Roel A RA; Collier, David A DA; St Clair, David D; Rietschel, Marcella M; Cichon, Sven S; Stefansson, Hreinn H; Rujescu, Dan D; Stefansson, Kari K
The schizophrenia risk allele C of the TCF4 rs9960767 polymorphism disrupts sensorimotor gating in schizophrenia spectrum and healthy volunteers.
The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience
Quednow, Boris B BB; Ettinger, Ulrich U; Mössner, Rainald R; Rujescu, Dan D; Giegling, Ina I; Collier, David A DA; Schmechtig, Anne A; Kühn, Kai-Uwe KU; Möller, Hans-Jürgen HJ; Maier, Wolfgang W; Wagner, Michael M; Kumari, Veena V
Dysfunctional gene splicing as a potential contributor to neuropsychiatric disorders.
American Journal Of Medical Genetics. Part B, Neuropsychiatric Genetics : The Official Publication Of The International Society Of Psychiatric Genetics
Glatt, Stephen J SJ; Cohen, Ori S OS; Faraone, Stephen V SV; Tsuang, Ming T MT
The Machado-Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability.
Human Molecular Genetics
Durcan, Thomas M TM; Kontogiannea, Maria M; Thorarinsdottir, Thorhildur T; Fallon, Lara L; Williams, Aislinn J AJ; Djarmati, Ana A; Fantaneanu, Tadeu T; Paulson, Henry L HL; Fon, Edward A EA
Stefansson, Hreinn H; Ophoff, Roel A RA; Steinberg, Stacy S; Andreassen, Ole A OA; Cichon, Sven S; Rujescu, Dan D; Werge, Thomas T; Pietiläinen, Olli P H OP; Mors, Ole O; Mortensen, Preben B PB; Sigurdsson, Engilbert E; Gustafsson, Omar O; Nyegaard, Mette M; Tuulio-Henriksson, Annamari A; Ingason, Andres A; Hansen, Thomas T; Suvisaari, Jaana J; Lonnqvist, Jouko J; Paunio, Tiina T; Børglum, Anders D AD; Hartmann, Annette A; Fink-Jensen, Anders A; Nordentoft, Merete M; Hougaard, David D; Norgaard-Pedersen, Bent B; Böttcher, Yvonne Y; Olesen, Jes J; Breuer, René R; Möller, Hans-Jürgen HJ; Giegling, Ina I; Rasmussen, Henrik B HB; Timm, Sally S; Mattheisen, Manuel M; Bitter, István I; Réthelyi, János M JM; Magnusdottir, Brynja B BB; Sigmundsson, Thordur T; Olason, Pall P; Masson, Gisli G; Gulcher, Jeffrey R JR; Haraldsson, Magnus M; Fossdal, Ragnheidur R; Thorgeirsson, Thorgeir E TE; Thorsteinsdottir, Unnur U; Ruggeri, Mirella M; Tosato, Sarah S; Franke, Barbara B; Strengman, Eric E; Kiemeney, Lambertus A LA; , ; Melle, Ingrid I; Djurovic, Srdjan S; Abramova, Lilia L; Kaleda, Vasily V; Sanjuan, Julio J; de Frutos, Rosa R; Bramon, Elvira E; Vassos, Evangelos E; Fraser, Gillian G; Ettinger, Ulrich U; Picchioni, Marco M; Walker, Nicholas N; Toulopoulou, Timi T; Need, Anna C AC; Ge, Dongliang D; Yoon, Joeng Lim JL; Shianna, Kevin V KV; Freimer, Nelson B NB; Cantor, Rita M RM; Murray, Robin R; Kong, Augustine A; Golimbet, Vera V; Carracedo, Angel A; Arango, Celso C; Costas, Javier J; Jönsson, Erik G EG; Terenius, Lars L; Agartz, Ingrid I; Petursson, Hannes H; Nöthen, Markus M MM; Rietschel, Marcella M; Matthews, Paul M PM; Muglia, Pierandrea P; Peltonen, Leena L; St Clair, David D; Goldstein, David B DB; Stefansson, Kari K; Collier, David A DA