GDF15 c.*70G>C

Variant ID: 19-18499815-G-C

NM_004864.2(GDF15):c.*70G>C

This variant was identified in 19 publications

View GRCh38 version.




Publications:


JAK-STAT signaling in inflammatory breast cancer enables chemotherapy-resistant cell states.

Cancer Research
Stevens, Laura E LE; Peluffo, Guillermo G; Qiu, Xintao X; Temko, Daniel D; Fassl, Anne A; Li, Zheqi Z; Trinh, Anne A; Seehawer, Marco M; Jovanovic, Bojana B; Aleckovic, Masa M; Wilde, Callahan M CM; Geck, Renee C RC; Shu, Shaokun S; Kingston, Natalie L NL; Harper, Nicholas W NW; Almendro, Vanessa V; Pyke, Alanna L AL; Egri, Shawn B SB; Papanastasiou, Malvina M; Clement, Kendell K; Zhou, Ningxuan N; Walker, Sarah S; Salas, Jacqueline J; Park, So Yeon SY; Frank, David A DA; Meissner, Alexander A; Jaffe, Jacob D JD; Sicinski, Piotr P; Toker, Alex A; Michor, Franziska F; Long, Henry W HW; Overmoyer, Beth A BA; Polyak, Kornelia K
Publication Date: 2022-11-21

Variant appearance in text: rs1054564
PubMed Link: 36409824
Variant Present in the following documents:
  • can-22-0423_supplementary_table_s3_suppst3.xlsx, sheet 1
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Rs6757 in microRNA-3976 binding site of CD147 confers risk of hepatocellular carcinoma in South Chinese population.

World Journal Of Surgical Oncology
Guo, Fenfen F; Li, Hong H; Wang, Lizhong L; Song, Xiaoping X; Wang, Jiangfeng J; Feng, Qingqing Q; Zong, Jinbao J
Publication Date: 2022-08-17

Variant appearance in text: rs1054564
PubMed Link: 35978360
Variant Present in the following documents:
  • 12957_2022_Article_2724.pdf
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Emerging roles of growth differentiation factor-15 in brain disorders (Review).

Experimental And Therapeutic Medicine
Jiang, Wei-Wei WW; Zhang, Zi-Zhen ZZ; He, Ping-Ping PP; Jiang, Li-Ping LP; Chen, Jin-Zhi JZ; Zhang, Xing-Ting XT; Hu, Mi M; Zhang, Yang-Kai YK; Ouyang, Xin-Ping XP
Publication Date: 2021-11

Variant appearance in text: rs1054564
PubMed Link: 34594407
Variant Present in the following documents:
  • Main text
  • etm-22-05-10705.pdf
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Disseminated Talaromyces marneffei Infection in a Non-HIV Infant With a Homozygous Private Variant of RELB.

Frontiers In Cellular And Infection Microbiology
Ding, Xiaofang X; Huang, Han H; Zhong, Lili L; Chen, Min M; Peng, Fang F; Zhang, Bing B; Cui, Xinyu X; Yang, Xiu-An XA
Publication Date: 2021

Variant appearance in text: rs1054564
PubMed Link: 33791233
Variant Present in the following documents:
  • Table_2.xlsx, sheet 1
View BVdb publication page



Assessing the Associations of Growth Differentiation Factor 15 with Rheumatic Diseases Using Genetic Data.

Clinical Epidemiology
Ye, Ding D; Liu, Bin B; He, Zhixing Z; Huang, Lin L; Qian, Yu Y; Shao, Keding K; Wen, Chengping C; Mao, Yingying Y
Publication Date: 2021

Variant appearance in text: rs1054564
PubMed Link: 33790654
Variant Present in the following documents:
  • Main text
  • clep-13-245.pdf
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The impact of growth differentiation factor 15 on the risk of cardiovascular diseases: two-sample Mendelian randomization study.

Bmc Cardiovascular Disorders
Wang, Zhuo Z; Yang, Fangkun F; Ma, Menghuai M; Bao, Qinyi Q; Shen, Jinlian J; Ye, Feiming F; Xie, Xiaojie X
Publication Date: 2020-10-28

Variant appearance in text: rs1054564
PubMed Link: 33115406
Variant Present in the following documents:
  • Main text
  • 12872_2020_Article_1744.pdf
View BVdb publication page



Growth differentiation factor 15 in adverse cardiac remodelling: from biomarker to causal player.

Esc Heart Failure
Wesseling, Marian M; de Poel, Julius H C JHC; de Jager, Saskia C A SCA
Publication Date: 2020-08

Variant appearance in text: rs1054564
PubMed Link: 32424982
Variant Present in the following documents:
  • Main text
View BVdb publication page



GDF15: A Hormone Conveying Somatic Distress to the Brain.

Endocrine Reviews
Lockhart, Samuel M SM; Saudek, Vladimir V; O'Rahilly, Stephen S
Publication Date: 2020-08-01

Variant appearance in text: rs1054564
PubMed Link: 32310257
Variant Present in the following documents:
  • Main text
View BVdb publication page



HNRNPA2/B1 is upregulated in endocrine-resistant LCC9 breast cancer cells and alters the miRNA transcriptome when overexpressed in MCF-7 cells.

Scientific Reports
Klinge, Carolyn M CM; Piell, Kellianne M KM; Tooley, Christine Schaner CS; Rouchka, Eric C EC
Publication Date: 2019-07-01

Variant appearance in text: rs1054564
PubMed Link: 31263129
Variant Present in the following documents:
  • 41598_2019_Article_45636.pdf
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Evaluation of GDF15 as a therapeutic target of cardiometabolic diseases in human: A Mendelian randomization study.

Ebiomedicine
Cheung, Ching-Lung CL; Tan, Kathryn C B KCB; Au, Philip C M PCM; Li, Gloria H Y GHY; Cheung, Bernard M Y BMY
Publication Date: 2019-03

Variant appearance in text: rs1054564
PubMed Link: 30772304
Variant Present in the following documents:
  • Main text
View BVdb publication page



Evidence GDF15 Plays a Role in Familial and Recurrent Hyperemesis Gravidarum.

Geburtshilfe Und Frauenheilkunde
Fejzo, Marlena S MS; Arzy, Daria D; Tian, Rayna R; MacGibbon, Kimber W KW; Mullin, Patrick M PM
Publication Date: 2018-09

Variant appearance in text: rs1054564
PubMed Link: 30258246
Variant Present in the following documents:
  • Main text
View BVdb publication page



A Meta-Analysis of Genome-Wide Association Studies of Growth Differentiation Factor-15 Concentration in Blood.

Frontiers In Genetics
Jiang, Jiyang J; Thalamuthu, Anbupalam A; Ho, Jennifer E JE; Mahajan, Anubha A; Ek, Weronica E WE; Brown, David A DA; Breit, Samuel N SN; Wang, Thomas J TJ; Gyllensten, Ulf U; Chen, Ming-Huei MH; Enroth, Stefan S; Januzzi, James L JL; Lind, Lars L; Armstrong, Nicola J NJ; Kwok, John B JB; Schofield, Peter R PR; Wen, Wei W; Trollor, Julian N JN; Johansson, Åsa Å; Morris, Andrew P AP; Vasan, Ramachandran S RS; Sachdev, Perminder S PS; Mather, Karen A KA
Publication Date: 2018

Variant appearance in text: rs1054564
PubMed Link: 29628937
Variant Present in the following documents:
  • Main text
  • fgene-09-00097.pdf
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A GDF15 3' UTR variant, rs1054564, results in allele-specific translational repression of GDF15 by hsa-miR-1233-3p.

Plos One
Teng, Ming-Sheng MS; Hsu, Lung-An LA; Juan, Shu-Hui SH; Lin, Wen-Chi WC; Lee, Ming-Cheng MC; Su, Cheng-Wen CW; Wu, Semon S; Ko, Yu-Lin YL
Publication Date: 2017

Variant appearance in text: rs1054564
PubMed Link: 28806401
Variant Present in the following documents:
  • Main text
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Growth Differentiation Factor 15 May Predict Mortality of Peripheral and Coronary Artery Diseases and Correlate with Their Risk Factors.

Mediators Of Inflammation
Hsu, Lung-An LA; Wu, Semon S; Juang, Jyh-Ming Jimmy JJ; Chiang, Fu-Tien FT; Teng, Ming-Sheng MS; Lin, Jeng-Feng JF; Huang, Hsuan-Li HL; Ko, Yu-Lin YL
Publication Date: 2017

Variant appearance in text: rs1054564
PubMed Link: 28798540
Variant Present in the following documents:
  • Main text
  • 9398401.f1.pdf
  • MI2017-9398401.pdf
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Whole-exome sequencing analysis of Waardenburg syndrome in a Chinese family.

Human Genome Variation
Chen, Dezhong D; Zhao, Na N; Wang, Jing J; Li, Zhuoyu Z; Wu, Changxin C; Fu, Jie J; Xiao, Han H
Publication Date: 2017

Variant appearance in text: rs1054564
PubMed Link: 28690861
Variant Present in the following documents:
  • hgv201727-s1.xls, sheet 1
View BVdb publication page



Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15.

Human Molecular Genetics
Ek, Weronica E WE; Hedman, Åsa K ÅK; Enroth, Stefan S; Morris, Andrew P AP; Lindgren, Cecilia M CM; Mahajan, Anubha A; Gustafsson, Stefan S; Gyllensten, Ulf U; Lind, Lars L; Johansson, Åsa Å
Publication Date: 2016-02-15

Variant appearance in text: rs1054564
PubMed Link: 26681806
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical and genetic correlates of growth differentiation factor 15 in the community.

Clinical Chemistry
Ho, Jennifer E JE; Mahajan, Anubha A; Chen, Ming-Huei MH; Larson, Martin G MG; McCabe, Elizabeth L EL; Ghorbani, Anahita A; Cheng, Susan S; Johnson, Andrew D AD; Lindgren, Cecilia M CM; Kempf, Tibor T; Lind, Lars L; Ingelsson, Erik E; Vasan, Ramachandran S RS; Januzzi, James J; Wollert, Kai C KC; Morris, Andrew P AP; Wang, Thomas J TJ
Publication Date: 2012-11

Variant appearance in text: rs1054564
PubMed Link: 22997280
Variant Present in the following documents:
  • Main text
View BVdb publication page



Macrophage inhibitory cytokine 1: a new prognostic marker in prostate cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Brown, David A DA; Lindmark, Fredrik F; Stattin, Pär P; Bälter, Katarina K; Adami, Hans-Olov HO; Zheng, Sigun L SL; Xu, Jianfeng J; Isaacs, William B WB; Grönberg, Henrik H; Breit, Samuel N SN; Wiklund, Fredrik E FE
Publication Date: 2009-11-01

Variant appearance in text: rs1054564
PubMed Link: 19843661
Variant Present in the following documents:
  • Main text
View BVdb publication page